Clinical trials: Strain
Myocardial Dysfunction
Effects of L-arginine on Myocardial Energetic Efficiency and Global Longitudinal Strain
The study is designed to evaluate the effects of L-arginine on myocardial structure and function and circulating microRNAs in patients with arterial hypertension.
- Trial name
- BIOCARDIO (NCT04626375)
- Testing
- Bioarginine
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Federico II University
Hamstring Muscle Strain, Skeletal Muscle Injury
BPC 157 for Acute Hamstring Muscle Strain Repair
This randomized, double-blind, placebo-controlled Phase 2 study evaluates whether pentadecapeptide BPC 157 (BPC-157), an investigational peptide, can speed structural healing and functional recovery after an acute grade II…
- Trial name
- BPC-HAMSTR (NCT07437547)
- Testing
- Pentadecapeptide BPC 157
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hudson Biotech
Antibiotic Resistant Infection, Antibiotic Resistant Strain
ESBL in Patients Returning to Sweden With Traveller's Diarrhoea
Patients with traveller's diarrhoea frequently harbour Extended Spectrum Betalactamase (ESBL)-producing Enterobacteriaceae (EPE) returning from EPE-endemic areas.
- Conditions
- Antibiotic Resistant Infection, Antibiotic Resistant Strain, Traveler's Diarrhea
- Trial name
- NCT03866291
- Testing
- No intervention, observational
- Where
- Sweden
- Volunteers
- 305 people
- Sponsor
- Lund University
Heat Exposure, Healthy
Safe Indoor Temperature Limit for Fans
Extreme heat events are a significant global threat to health and wellbeing, and result in more morbidity and mortality than all other natural disasters combined.
- Conditions
- Heat Exposure, Healthy, Young Adults, Fans
- Trial name
- NCT06584903
- Testing
- Temperature Ramp Protocol
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Arrhythmogenic Cardiomyopathy
Statin Effect on Arrhythmogenic Cardiomyopathy Disease Progression (SEARCH)
The goal of this clinical trial is to learn if Atorvastatin 80 mg is effective to avoid functional right ventricular deterioration in patients affected by Arrhythmogenic Cardiomyopathy.
- Trial name
- SEARCH (NCT06922994)
- Testing
- Atorvastatin 80 mg/day
- Where
- 5 sites in Italy
- Volunteers
- 102 people
- Sponsor
- Centro Cardiologico Monzino
Heart Failure, Atrial Fibrillation
Statins in Reducing Events in the Elderly (STAREE) Heart Sub-study
The STAREE-HEART sub-study will examine the effect of statin treatment over a 3-year period compared with placebo on markers of cardiac ageing (myocardial dysfunction).
- Conditions
- Heart Failure, Atrial Fibrillation, Healthy Ageing, Hypercholesterolemia
- Trial name
- STAREE-HEART (NCT04536870)
- Testing
- Echocardiography, ECG screening
- Where
- 2 sites in Australia
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Monash University
Ulcerative Colitis in Remission
Evaluation of ProLife 10 FORTE on Gut Microbiota Composition in UC Patients
This clinical trial aims to learn if the probiotic Prolife 10 Forte could improve the Gut Microbiota composition of Ulcerative colitis patients during the remission phase.
- Trial name
- ProZ-UC (NCT06642883)
- Testing
- Prolife
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Padova
Aortic Valve Disorder
2D Strain of Right Ventricle in Peroperative of Cardiac Surgery
Evaluation of the right ventricle (RV) deformation (strain) with 2D speckle tracking technics obtained by echocardiographies (TEE) in peroperative period of cardiac surgery .
- Trial name
- NCT03298932
- Testing
- Aortic valve surgery
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Constipation
Efficacy of Lacticaseibacillus Paracasei Strain Shirota on Clinical Manifestation of Functional Constipation in Mexican Adults
Chronic functional constipation is a gastrointestinal disorder with an approximate prevalence of 14% of the Mexican population, which is characterized by difficult or incomplete defecation and/or infrequent bowel movements, with…
- Trial name
- FC (NCT06432608)
- Testing
- fermented milk, Yakult
- Volunteers
- 50 people
- Sponsor
- University of Guadalajara
Underweight, Paediatrics
Impact of Bi-26 Supplementation on Weight Gain in Underweight Infants
The burden of disease experienced by underweight children is significant, particularly in low- and middle-income countries. Gut dysbiosis, an imbalance in microbial composition, is thought to play a role in nutrient malabsorption…
- Trial name
- NCT05952076
- Testing
- B. infantis Bi-26
- Where
- 5 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Gates Medical Research Institute
Muscle Strain, Neuromuscular Diseases
Posterior Chain EMG Patterns in Athletes With and Without Hamstring Injury
This cross-sectional observational study investigated posterior chain muscle activation patterns in football players with and without a history of hamstring strain injury.
- Conditions
- Muscle Strain, Neuromuscular Diseases, Athletic Injuries
- Trial name
- NCT07171385
- Testing
- Nordic Hamstring Curl (NHC), Kettlebell Swing (KS), Supine Sliding Single-Leg Curl (SSLC)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Dry Eye
Bilberry-containing Capsules for Dry Eye Mitigation
This study investigates whether the oral intake of a bilberry capsule product may relieve dry eye symptoms. Participants will be aged between 20 - 65 years of age, with confirmed diagnosis of dry eye status.
- Trial name
- NCT05737108
- Testing
- Bilberry capsule product
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chung Shan Medical University
Right Ventricular Failure, Pulmonary Embolism
Quantitative Assessment of RV Strain Using cMRI Following Catheter Intervention on PE
Acute pulmonary embolism (PE) is a condition in which the vessels carrying blood to the lungs become suddenly blocked, usually by a blood clot.
- Trial name
- RVEF (NCT03341208)
- Testing
- Cardiac Magnetic Resonance Imaging
- Volunteers
- 10 people
- Sponsor
- University of Arizona
Poliomyelitis
Consistency Study for Three Commercial Lots of Inactivated Poliomyelitis Vaccine Made From Sabin Strain
A randomized and blind clinical consistency study for three commercial batches of Inactivated Poliomyelitis Vaccine Made From Sabin Strain (sIPV) for immunogenicity and safety evaluation.
- Trial name
- NCT04224519
- Testing
- sIPV batch 1, sIPV batch 2, sIPV batch 3
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Sprain, Strain
Efficacy and Safety of Ketoprofen Topical Patch 20% in the Treatment of Pain Associated With Ankle Sprain or Strain
The purpose of this study is to evaluate the effect of a ketoprofen topical patch on the pain associated with ankle sprain or strain.
- Trial name
- NCT00351104
- Testing
- Ketoprofen Topical Patch 20%
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Alkemira SA
SARS-CoV-2 Infection
Dose, Safety and Pathogenicity of SARS-CoV-2 (COVID-19) Omicron Virus (BA.5)
An Exploratory Study to Establish the Dose, Safety and Pathogenicity of a SARS-CoV-2 Omicron Challenge Strain (BA.5) in Healthy Participants 18 to 40 Years of Age
- Trial name
- NCT06492564
- Testing
- SARS-CoV-2 omicron virus dose arm 1, SARS-CoV-2 omicron virus dose arm 2, SARS-CoV-2 omicron virus dose arm 3
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hvivo
Anterior Pelvic Tilt, Sprint Kinematics
"Ecological Program Changes Pelvic Kinematics in Soccer Players: Pilot Study on Hamstring Injury Implications"
The present pilot study aimed to investigate whether a 6-week multicomponent intervention, comprising a structural lumbopelvic and sprint technique program, could reduce anterior pelvic tilt in soccer players who regularly…
- Trial name
- NCT06551532
- Testing
- Multicomponent program
- Where
- Spain
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- RX2 Sports and Health
Ischemic Heart Disease, Valvular Heart Disease
Milrinone on Right Ventricular Strain in Cardiac Surgery
The purpose of this study is to analyze the changes in right ventricular strain before and after milrinone administration in order to find out whether milrinone improves RV systolic performance in patients undergoing cardiac…
- Trial name
- NCT06077721
- Testing
- Milrinone
- Where
- South Korea
- Volunteers
- 41 people
- Sponsor
- Konkuk University Medical Center
Escherichia Infection
Efficacy Study of IM Administered CssBA+dmLT Against Moderate-severe Diarrhea in Human Infection Model With ETEC Strain B7A in Healthy Adults
The study is designed to evaluate the safety, immunogenicity, and efficacy of the intramuscular administration of a CS6 based vaccine (CssBA) against ETEC co-administered with double mutant labile toxin (dmLT) in preventing…
- Trial name
- NCT06692907
- Testing
- B7A (ETEC challenge strain), CssBA, dmLT
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Gastrointestinal Symptoms
Effect of Bifidobacterium Lactis HN019 on Colonic Transit Time and Digestive Symptoms
The purpose of this study was to investigate the dose response effect of Bifidobacterium lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms.
- Trial name
- NCT01171014
- Testing
- Bifidobacterium lactis HN019
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fonterra Research Centre