Clinical trials: Stratification
Syncope
Comparison Between Standard and Ultrasound Integrated Approach for Risk Stratification of Syncope in the Emergency Department
This is a observational prospective study. For patients presenting to the Emergency Department with loss of consciousness, emergency physicians will be asked to screen the real syncope without an evident and immediate cause for…
- Trial name
- NCT02781207
- Where
- Italy
- Volunteers
- 196 people
- Sponsor
- University of Turin, Italy
Acute Myocardial Infarction
SILVER-AMI: Outcomes in Older Persons With Heart Attacks
SILVER-AMI is a research study of older persons who are admitted to the hospital with a heart attack. Patients will be interviewed in the hospital and again 6 months later.
- Trial name
- SILVER-AMI (NCT01755052)
- Where
- 81 sites in United States
- Volunteers
- 3,042 people
- Sponsor
- Yale University
Papillary Thyroid Carcinoma, Recurrence Free Survival
Clinicopathological Predictors of Recurrence in Papillary Thyroid Carcinoma
The goal of this observational study is to identify demographic and clinicopathological factors associated with disease recurrence in adults with histologically confirmed papillary thyroid carcinoma (PTC) who achieved an initial…
- Trial name
- NCT07695974
- Where
- Italy
- Volunteers
- 1,113 people
- Sponsor
- University of Roma La Sapienza
Preventive Cardiology, Respiration Disorders
"ADEN Platform: Pilot Clinical Validation for Chronic Disease Risk Stratification in Colombia"
This protocol describes a 90-day prospective pilot study designed to validate the capacity of the ADEN clinical intelligence platform to stratify early chronic disease risk across six priority public health profiles in Colombia.
- Conditions
- Preventive Cardiology, Respiration Disorders, Oncologic Disease, Autoimmune
- Trial name
- VALIDATES (NCT07727915)
- Testing
- Molecular Target
- Where
- Colombia
- Volunteers
- 120 people
- Sponsor
- Unidad de Investigación Genética Molecular
Pituitary Adenoma
Pre-operative Surgical Difficulty Stratification Using Predicted Tumor Perfusion and Consistency
Pituitary adenomas (PAs) are among the most prevalent lesions of the sella turcica, accounting for 10%-25% of all intracranial neoplasms. Pituitary macroadenomas (PMAs) are defined with a maximum diameter of over 1 cm.
- Trial name
- NCT06664190
- Testing
- Advanced sequences, such as arterial spin labeling (ASL) and diffusion-weighted imaging (DWI)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Huashan Hospital
Opioid Use
Opioid Use in Shoulder Arthroplasty Patients: A Stratification and Algorithm
The investigators aim to better understand opioid use in patients undergoing elective shoulder surgery. The investigators will prospectively determine actual postoperative opioid use, while evaluating whether implementation of an…
- Trial name
- NCT03808025
- Testing
- opioid education
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Advanced Chronic Liver Disease, Surgery--Complications
Non-invasive Methods and Surgical Risk Stratification in Cirrhotics Undergoing Elective Extrahepatic Surgery
The ELASTO-SURGERY study aims to evaluate the prognostic role of portal hypertension evaluated by non-invasive methods in predicting post-operative morbidity (at 90 days) and mortality (at 365 days) in patients with advanced…
- Trial name
- NCT04615091
- Where
- 37 sites in United States, Austria and 10 more
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Hematologic Tests
Risk Stratification in Acutely Admitted Medical Patients
The study has three main parts. 1. To see if we can develop a riskstratification tool that can be used to asses the risk for acutely admitted medical patients for inhospital death, admission to the ICU and death within 30 days of…
- Trial name
- NCT00768547
- Where
- Denmark
- Volunteers
- 5,900 people
- Sponsor
- Ribe County Hospital
Intrahepatic Cholangiocarcinoma
Next Generation Sequencing in Intrahepatic Cholangiocarcinoma
The aim of the present study is to perform a comprehensive molecular characterization of intrahepatic cholangiocarcinoma (ICC) in patients exposed to well-known or putative risk factors (such as asbestos) for this malignancy, in…
- Trial name
- EtherBil (NCT02184871)
- Testing
- exposure to different risk factors and molecular assessment
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- University of Bologna
Perioperative Care
Validation of B-type Natriuretic Peptide With N-terminal Pro B-type Natriuretic Peptide in Perioperative Risk Assessment
This is a single-centre, prospective study to determine the correlation and comparative thresholds between N-terminal pro-brain natriuretic peptide (NT ProBNP, Roche) and brain natriuretic peptide (BNP, Abbott) tests.
- Trial name
- NCT05352698
- Testing
- NT ProBNP (Roche)
- Where
- Canada
- Volunteers
- 466 people
- Sponsor
- Jordan Leitch
Ischemia, Myocardial, Ischemic Heart Disease
Coronary Flow Reserve (CFR) in Cardiovascular Risk Stratification
CFR has been studied for few years using 82 Rubidium PET (positron emission tomography) /CT. CFR has shown to be correlated with cardiovascular events occurring in the 10 following years.
- Trial name
- CFR-OR (NCT03586492)
- Testing
- CZT SPECT acquisition
- Where
- 2 sites in France
- Volunteers
- 137 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Inflammatory Bowel Disease, Inflammatory Bowel Disease (IBD)
Automated Clinical Pathway for Inflammatory Bowel Disease Care
Pragmatic randomized controlled trial to evaluate the effect of an electronic medical record-based tool on improving on-time follow up and its effects on inflammatory bowel disease outcomes
- Trial name
- NCT07167836
- Testing
- Electronic medical record-based care pathway
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Ventricular Arrhythmias, Implantable Defibrillator User
Scandinavian Multicenter Study to Advance Risk Stratification in Heart Disease- Ventricular Arrhythmias
The purpose of this study is to identify markers of increased risk for incident ventricular arrhythmias and cardiovascular events in patients already being treated with an implantable cardioverter-defibrillator (ICD) by exploring…
- Conditions
- Ventricular Arrhythmias, Implantable Defibrillator User, Biological Markers, Heart Disease
- Trial name
- SMASH 1 (NCT02864771)
- Where
- Norway
- Volunteers
- 504 people
- Sponsor
- University Hospital, Akershus
Acute Coronary Syndrome
Early Risk Stratification in ED Chest Pain Patients
In the management of adult chest pain patients presenting to an Emergency Department (ED) with suspected acute coronary syndrome (ACS), we aimed to evaluate the diagnostic accuracy of the combined use of a modified Thrombolysis…
- Trial name
- NCT02364271
- Testing
- Thrombolysis in myocardial infarction score, routine blood test for hs-cTnT, HEART score
- Where
- China
- Volunteers
- 602 people
- Sponsor
- Chinese University of Hong Kong
Endometrial Cancer
Individualised Endometrial Cancer Risk Stratification by Bayesian Prediction Model (ENDORISK), Optimizing Clinical Implementation
Rationale: Preoperative identification of patients at risk for lymph node metastasis (LNM) is challenging in endometrial cancer (EC).
- Trial name
- ENDORISK-I (NCT07200466)
- Testing
- ENDORISK personalized risk assesment for lymph node metastases in endometrial cancer.
- Where
- 14 sites in Netherlands
- Volunteers
- 735 people
- Sponsor
- Radboud University Medical Center
Lung Cancer Screening
LUNG-07: Advancing Precision-Based Lung Cancer Screening: Implementation, AI-Guided Risk Stratification, and Biomarker Integration (CREST AI)
This research study aims to investigate methods for enhancing lung cancer screening. The study will investigate whether an artificial intelligence (AI) tool, known as Sybil, can aid in predicting the risk of lung cancer.
- Trial name
- NCT07408531
- Testing
- Sybil Artificial Intelligence (AI) screening
- Where
- 2 sites in United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Infection
NEWS2+Procalcitonin Association in Patients With Infection and Its Significance in Oncological Patients
This observational study aims to evaluate the prognostic significance of the combination of a clinical score (specifically, a score obtained through the measurement of multiple parameters such as blood pressure, body temperature…
- Trial name
- NCT06761118
- Where
- Italy
- Volunteers
- 1,041 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Toxic Encephalopathy, Diquat Poisoning
Risk Stratification and Heterogeneity for Organ Damage in Acute Diquat Poisoning
This ambispective cohort study aims to characterize the relationship between plasma diquat concentrations and organ damage risk.
- Trial name
- NCT06798142
- Testing
- extracorporeal treatment
- Where
- China
- Volunteers
- 193 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Sleep Apnea, Sudden Cardiac Death
European Sleep Apnea and Sudden CArdiac Death ProjEct
The objective of ESCAPE-SCD Study is assessment of the effect of sleep apnea on sudden cardiac death risk and cardiovascular outcomes in patients with ischemic cardiomyopathy.
- Conditions
- Sleep Apnea, Sudden Cardiac Death, Heart Failure, Ischemic Cardiomyopathy
- Trial name
- ESCAPE-SCD (NCT02506166)
- Testing
- Positive Airway Pressure Therapy
- Volunteers
- 900 people
- Sponsor
- University Hospital Olomouc
Diabetes Mellitus, Type 2, PreDiabetes
Prediabetes Stratification by Multi-omics Profile After Food Intake
1 in 3 adults have prediabetes in the United States, and many of them will eventually develop diabetes, which has significant public health and economic costs.
- Trial name
- NCT06005051
- Testing
- Dietary intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University