Clinical trials: Stratification
Chronic Kidney Disease
The Role of P-cresol and Related Protein Fermentation Metabolites in Chronic Kidney Disease Patients
Study on the natural history of uremic retention solutes in patients with mild-to-moderate chronic kidney disease
- Trial name
- NCT00441623
- Testing
- observational
- Where
- Belgium
- Volunteers
- 499 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stem Cell Transplantation, Pediatric Cancer
Feasibility Neurocognitive Outcome After Transplant
This pilot study will primarily be evaluated by feasibility and adherence to an iPad-based neurocognitive intervention program. It will secondarily be evaluated by performance on the neurocognitive testing post-transplant and…
- Conditions
- Stem Cell Transplantation, Pediatric Cancer, Acute Lymphoblastic Leukemia
- Trial name
- NCT02300961
- Testing
- Cognitive rehabilitation program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Stanford University
Non-severe Pulmonary Embolism, Pulmonary Embolism
Interest of the Chair Lift Test in the Prognostic Evaluation of Pulmonary Embolism: a Single-center Open Prospective Study
The objective of the study is to evaluate the prognostic performance of the chair lift test in the initial assessment of the severity of non-severe pulmonary embolism in hospitalized patients, in comparison with the current…
- Conditions
- Non-severe Pulmonary Embolism, Pulmonary Embolism, Non-high-risk Pulmonary Embolism, Pulmonary Embolism Acute
- Trial name
- SIT-EP (NCT06166329)
- Testing
- chair lift test
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Rouen
Surgical Site Infection (SSI), Central Nervous System Tumor
A Clinical Prediction Model for Surgical Site Infection After Central Nervous System Tumor Surgery
1. Study Background For patients undergoing brain or spinal tumor surgery, postoperative surgical wound infection (known as "surgical site infection," SSI) is a recognized risk.
- Trial name
- NCT07378683
- Testing
- ML-Based Enhanced Intervention Package for SSI Prevention, Standard Postoperative Care
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ming Yang
Aortic Aneurysm, Abdominal, Arterial Occlusive Diseases
The Use of Cardiovascular Biomarkers in Abdominal Aortic Surgery
The aim of the present study is the evaluation of cardiovascular biomarkers in patients with abdominal aortic aneurysms (AAA) or abdominal aortic occlusive disease AOD) undergoing open (OR) or endovascular aortic repair (EVAR)…
- Trial name
- BIAS (NCT02122497)
- Testing
- abdominal aortic surgery
- Where
- Austria
- Volunteers
- 500 people
- Sponsor
- Prim PD Dr Afshin Assadian
Histologically Confirmed Metastatic or Locally Advanced Breast Cancer With no Radical Topical Treatment Available, If There is Liver Metastasis, Which the Researcher Believes Will be Difficult to Evaluate the Response Accurately With Bone Metastasis or CT
FDG PET-CT in Advanced Breast Cancer
This study is a prospective cohort study comparing metabolic response evaluation by F-18 FDG PET-CT versus conventional imaging for outcome stratification in patients with advanced breast cancer receiving first-line systemic…
- Trial name
- PET-000 (NCT07173868)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Multiple Sclerosis
Prospective Stratification of Infectious Risks in Multiple Sclerosis
This monocentric study is to identify factors that increase the susceptibility for infections and establish a questionnaire-based infection score that allows a prospective stratification for infectious risks in patients with…
- Trial name
- InRIMS (NCT04036097)
- Testing
- MS-adapted AWIS questionnaire (MS-AWIS), infection diary (MS-AWIS diary)
- Where
- Switzerland
- Volunteers
- 298 people
- Sponsor
- University Hospital, Basel, Switzerland
Infectious Disease, Febrile Illness
A Rapid Triage Test to Improve Risk-stratification of Febrile Children (EChiLiBRiST, Clinical Trial 1, Outpatients)
The overall aim of the study is to provide evidence that introducing novel biomarkers evaluation at triaging (first clinical assessment), in combination with IMCI-based guidelines (SoC), is a viable strategy to enhance rapid and…
- Conditions
- Infectious Disease, Febrile Illness, Child, Only
- Trial name
- NCT06422338
- Testing
- IMCI-enhanced by suPAR levels (SoC + suPAR POC)
- Where
- 2 sites in Gabon, Mozambique
- Volunteers
- 5,212 people
- Sponsor
- Barcelona Institute for Global Health
Heart Failure, Diastolic, Multicenter Study
Diagnosis and OutcoMes evaluAtIoN of Multicenter Patients With HFpEF Using Multimodality Imaging
The incidence of Heart failure with preserved ejection fraction (HFpEF) in Heart failure patients increases rapidly. However, the current clinical awareness is insufficient, and the cardiac structural and functional injury are…
- Trial name
- NCT04602338
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Disease
Plaque Stratification Using Ccta in Coronary ARtery Disease (PoSTCARD)
Develop time-to-event prediction and plaque phenotype classification models for patients with known or suspected coronary artery disease.
- Trial name
- PoSTCARD (NCT04439643)
- Testing
- vascuCAP
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Elucid Bioimaging Inc.
Coronary Artery Calcification, HIV Infections
French CAC-HIV Cohort Study
Clinical study: Methods: observational transversal two-arm cohort study including adults living with HIV (PLHIV) and HIV negative subjects (HIV-) at intermediate cardiovascular risk.
- Trial name
- CAC-HIV (NCT05563116)
- Testing
- Computed tomography coronary artery calcium (CAC) score (part of routine workup)
- Volunteers
- 689 people
- Sponsor
- Franck Boccara
Acute Myocardial Infarction
CARISMA : Cardiac Arrhythmias and Risk Stratification After MyoCardial Infarction
The purpose of this study is to assess the incidence of tachy- and bradyarrhythmic episodes in patients with acute myocardial infarction with depressed ventricular function and to determine the predictive value of several…
- Trial name
- NCT00145119
- Where
- Netherlands
- Volunteers
- 312 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Biomarkers, ST Segment Elevation Myocardial Infarction
Biomarkers for Risk Stratification After STEMI
Despite modern reperfusion strategies, myocardial infarction leads to deleterious processes resulting in left ventricular remodelling (LVR) and heart failure (HF). Several biomarkers i.e.
- Conditions
- Biomarkers, ST Segment Elevation Myocardial Infarction, Primary Percutaneous Coronary Intervention, Heart Diseases
- Trial name
- NCT03735719
- Where
- Poland
- Volunteers
- 136 people
- Sponsor
- Medical University of Warsaw
Acute Coronary Syndromes (ACS)
Association Between SYNTAX Score and Leukoglycemic Index In Patients Wiht Acute Coronary Syndrome
This study looks at people who come to the hospital with acute coronary syndrome, a serious heart condition. When these patients first arrive, doctors take routine blood tests.
- Trial name
- NCT07276256
- Testing
- leukoglycemic index calculation
- Where
- Turkey (Türkiye)
- Volunteers
- 552 people
- Sponsor
- Kırıkkale University
Brugada Syndrome, Cardiac Arrest
Feasibility of Improving Risk Stratification in Brugada Syndrome
Feasibility of Improving Risk Stratification in Brugada Syndrome (BrS), retrospective cohort study To study the reproducibility and specificity of V-CoS for activation heterogeneities predisposing to VT/VF in a larger series of…
- Conditions
- Brugada Syndrome, Cardiac Arrest, Athletes Heart, Atrial Fibrillation
- Trial name
- FIRST-BrS (NCT03992677)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Imperial College London
CIDP, Chronic Inflammation
Ultrasound-driven Stratification in CIDP
Chronic inflammatory demyelinating polyradiculoneuritis (CIDP) is a rare autoimmune neuropathy characterized by significant clinical and therapeutic heterogeneity.
- Conditions
- CIDP, Chronic Inflammation, Demyelinating Polyneuropathy
- Trial name
- TAILOR-CIDP (NCT07719153)
- Testing
- Refractory CIDP, Standard-of-care treatment for CIDP
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
ST Elevation (STEMI) Myocardial Infarction, Non ST Elevation Myocardial Infarction (NSTEMI)
Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome
This study will evaluate clinical characteristics, frailty, and predictors of prognosis in patients aged 75 years and older who are hospitalized with acute coronary syndrome (ACS).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Non ST Elevation Myocardial Infarction (NSTEMI), Unstable Angina Pectoris
- Trial name
- NCT07366684
- Testing
- Percutaneous Coronary Intervention (PCI), Conservative Medical Therapy
- Where
- Serbia
- Volunteers
- 550 people
- Sponsor
- Clinical Center Niš
Thyroid Cancer, Atypia of Undetermined Significance
The Risk Stratification of Papillary Thyroid Cancer With AUS/FLUS by FNA
Purpose: To investigate the clinical characteristics of papillary thyroid cancer (PTC) with Bethesda category III (AUS/FLUS) by fine needle aspiration (FNA) and to assisted the precision treatment.
- Conditions
- Thyroid Cancer, Atypia of Undetermined Significance, FLUS
- Trial name
- NCT04601298
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Shanghai 10th People's Hospital
Atrial Fibrillation
Thromboembolic and Bleeding Risk Stratification in Patients With Non-valvular Atrial Fibrillation
The aim of the present prospective study is to further develop and validate a composite risk score predicting both ischemic and bleeding risk, based on epidemiologic, clinical, biological, and/or morphologic complementary data.
- Trial name
- FASTRHAC (NCT02741349)
- Where
- 4 sites in France
- Volunteers
- 825 people
- Sponsor
- Saint Antoine University Hospital
HEART FAILURE
Heart Failure STratification and OutcomeS
Background: Heart failure (HF) is in many cases the final way for coronary heart diseases. In older than 65 years is the most important cause of hospitalization.
- Trial name
- HEFESTOS (NCT02444676)
- Testing
- Stratification and outcomes
- Where
- Spain
- Volunteers
- 560 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina