Clinical trials: Stratification
Lung Cancer (Diagnosis)
Blood Based Risk Evaluation With AI for Targeted Primary Health Care in Early Lung Cancer Detection
The study is a prospective, non-randomized feasibility study evaluating blood sample and machine learning-based risk stratification for lung cancer in patients with COPD (chronic obstructive pulmonary disease).
- Trial name
- BREATHE (NCT07552584)
- Testing
- Risk stratification
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people
- Sponsor
- Vejle Hospital
Lung Cancer
Risk Stratification for Patients With Hospital-diagnosed Advanced Lung Cancer
This study explores whether supportive care interventions that might reduce rehospitalization could be implemented and feasible, in subjects within a high-risk group of subjects with newly diagnosed hospitalized advanced lung…
- Trial name
- NCT05722847
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Healthy
Gut Microbial Metabolism of Polyphenols and Cardiovascular Health (StratiPol) (Stratification Study)
There is increasing interest in the effects of various food derived polyphenols on cardiovascular health. Several studies have demonstrated improvements in vascular function after intake of polyphenol rich foods.
- Trial name
- StratiPol (NCT03573414)
- Testing
- raspberry powder, milled flaxseed and soy milk
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- King's College London
Bundle-Branch Block, Left, Cardiac Failure
Prognosis of Patients With Compete Left Bundle Branch Block
The investigators sought to evaluate the morphological and functional changes, risk stratification and prognosis of patients of participants with compete left bundle branch block (CLBBB).
- Conditions
- Bundle-Branch Block, Left, Cardiac Failure, ICD/Pacemaker Implantation, Cardiovascular Magnetic Resonance Imaging
- Trial name
- NCT03096678
- Testing
- Cardiac Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Acute Coronary Syndrome, Angina Pectoris
Mersey Acute Coronary Syndrome Rule-Out Using High Sensitive Troponin
The aim of this observational study is twofold. The primary hypothesis being tested is that initial(first) high sensitivity Tn <5ng/l (limit of detection) combined with an ECG with no ischaemic changes is superior as an…
- Conditions
- Acute Coronary Syndrome, Angina Pectoris, Cardiovascular Diseases, Chest Pain
- Trial name
- MACROS (NCT02581540)
- Volunteers
- 3,054 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Cardiovascular Diseases, Cardiovascular Risk Factor
Stratification Protocols and Clinical, Physical and Biochemical Parameters to Forecast Cardiovascular Intercurrences.
Introduction: Despite the various beneficial effects, cardiovascular rehabilitation programs (CVRP) have been associated with the appearance of signs and symptoms.
- Trial name
- NCT03446742
- Testing
- Cardiovascular rehabilitation
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Valvular Heart Disease Stenosis and Regurgitation
Natriuretic Peptides as a Prognostic and Risk Stratification Tool in Assessment of Valvular Heart Disease
NPs can be used To detect subset of asymptomatic with subtle LV dysfunction for further evaluation and earlier referral for intervention and its correlation with echocardiographic finding.
- Trial name
- NCT05439369
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension
Chinese PE Multimodality Imaging Artificial Intelligence Study
The CHinese pulmOnary Embolism Multimodality Imaging-artifiCial intelligencE Study (CHOICE) is a prospective observational multi-center study that will collect imaging text data and raw data of patients with pulmonary embolism…
- Conditions
- Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Disease
- Trial name
- NCT06526468
- Testing
- Artificial Intelligence
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- China-Japan Friendship Hospital
Covid19
Risk Stratification and Early Alerting Regarding COVID-19 Hospitalization
The purpose of this research is to remotely monitor individuals who have tested positive for COVID-19 to learn more about progression and recovery from the disease.
- Trial name
- RiskSEARCH (NCT04709068)
- Testing
- Current Health
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Current Health
Perioperative Cardiovascular Risk, Postoperative Complications (Cardiopulmonary)
AI-ECG for Preoperative Cardiovascular Risk Stratification Before General Surgery
This randomized controlled trial evaluates whether an artificial intelligence-enhanced electrocardiography (AI-ECG)-based strategy for preoperative cardiovascular risk stratification is noninferior to usual care in patients…
- Conditions
- Perioperative Cardiovascular Risk, Postoperative Complications (Cardiopulmonary), Preoperative Care
- Trial name
- NCT07774689
- Testing
- AI-ECG-based preoperative risk stratification (ECG Buddy)
- Where
- South Korea
- Volunteers
- 3,200 people
- Sponsor
- Seoul National University Bundang Hospital
Drug-Induced Liver Injury, Anti-Tuberculous Drug Reaction
Assessing Antibiotic Induced Liver Injury for Stratification of Tuberculosis Patients
A panel of highly sensitive circulating biomarkers for acute liver injury have been identified and demonstrated to identify liver injury on first presentation to hospital before standard tests are elevated in patients with…
- Conditions
- Drug-Induced Liver Injury, Anti-Tuberculous Drug Reaction, Tuberculosis
- Trial name
- ALISTER (NCT03211208)
- Where
- United Kingdom
- Volunteers
- 194 people
- Sponsor
- University of Edinburgh
Syncope, Presyncope
Practical Approaches to Care in Emergency Syncope
Syncope, or transient loss of consciousness, is a common reason for visit to the Emergency Department and often leads to extensive testing and hospitalization.
- Trial name
- PACES (NCT04533425)
- Where
- 5 sites in United States
- Volunteers
- 1,297 people
- Sponsor
- Columbia University
Endometrial Cancer, Adjuvant Radiotherapy
Study of Early Stage Endometrial Cancer Based on Molecular Classification and Traditional Risk Stratification to Guide Adjuvant Radiotherapy Decisions
The purpose of this study is to compare the efficacy and toxicity of early stage endometrial cancer based on molecular classification and conventional risk stratification adjuvant therapy decision-making, and to provide…
- Conditions
- Endometrial Cancer, Adjuvant Radiotherapy, Molecular Classification
- Trial name
- NCT05524389
- Testing
- Vaginal brachytherapy, Pelvic external beam radiotherapy, Observation
- Volunteers
- 624 people
- Sponsor
- Peking Union Medical College Hospital
Osteosarcoma
ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities
Post-authorization, observational, multicenter and prospective study in patients between 2 and 30 years old diagnosed with non-metastatic high-grade osteosarcoma of the extremities.
- Trial name
- NCT04383288
- Where
- 17 sites in Spain
- Volunteers
- 115 people
- Sponsor
- Grupo Espanol de Investigacion en Sarcomas
Gastrointestinal Hemorrhage
Artificial Intelligent Clinical Decision Support System Simulation Center Study for Technology Acceptance
The purpose of this research study is to measure the effect on of a large language model interface on the usability, attitudes, and provider trust when using a machine learning algorithm-based clinical decision support system in…
- Trial name
- NCT05816473
- Testing
- LLM
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Colorectal Neoplasms, Mass Screening
Preventing Early-Onset Colorectal Cancer in the VA
Colorectal cancer is a leading cause of cancer death among Veterans. The starting age for colorectal cancer screening has been lowered from 50 to 45 years in response to the rising incidence of early-onset colorectal cancer…
- Trial name
- PRECISE (NCT07071454)
- Testing
- Patient intervention, PCP intervention
- Where
- United States
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Lung Diseases, Obstructive, Postoperative Complications
Preoperative Self-assessment for Cardio-pulmonary Risk Stratification
This prospective study intends to development and validation a patient self-assessment questionnaire. The aim of the self-assessment, by questionnaire, is to estimate the risk of postoperative pulmonary complications (PPC).
- Conditions
- Lung Diseases, Obstructive, Postoperative Complications, Cardiac Event
- Trial name
- PRESELECT (NCT04156594)
- Where
- Germany
- Volunteers
- 5,500 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Heart Failure
Improving Risk Stratification of Emergency Department Patients With Acute Heart Failure
The primary goal is to build and test a previously developed and validated risk model and clinical decision support tool embedded within the electronic health record to improve risk stratification of emergency department (ED)…
- Trial name
- NCT06065761
- Testing
- Comprehensive ED heart failure management tool
- Where
- 21 sites in United States
- Volunteers
- 17,459 people
- Sponsor
- Kaiser Permanente
Covid19
Risk Stratification of COVID-19 Patients Discharged From the Emergency Department
Risk stratification of COVID-19 patients is essential to define their appropriate treatment setting. So far, available studies have focused on morbidity and mortality prediction in patients admitted to hospital.
- Trial name
- CODED (NCT04629183)
- Testing
- integrated clinical evaluation
- Where
- 7 sites in Italy
- Volunteers
- 742 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Systemic Mycosis
Optimized Diagnostics for Improved Therapy Stratification in Invasive Fungal Infections
Invasive fungal infections (IFI) in immunocompromised patients pose a major challenge for diagnostics designed to permit timely onset of appropriate treatment.
- Trial name
- FUNGITECT (NCT02492594)
- Testing
- Peripheral blood sampling
- Where
- 7 sites in Austria, Netherlands and 1 more
- Volunteers
- 244 people
- Sponsor
- St. Anna Kinderkrebsforschung