Clinical trials: Stratification
ST Elevation (STEMI) Myocardial Infarction, Non ST Elevation Myocardial Infarction (NSTEMI)
Clinical Characteristics, Frailty, and Prognostic Predictors in Patients Aged 75 and Older With Acute Coronary Syndrome
This study will evaluate clinical characteristics, frailty, and predictors of prognosis in patients aged 75 years and older who are hospitalized with acute coronary syndrome (ACS).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Non ST Elevation Myocardial Infarction (NSTEMI), Unstable Angina Pectoris
- Trial name
- NCT07366684
- Testing
- Percutaneous Coronary Intervention (PCI), Conservative Medical Therapy
- Where
- Serbia
- Volunteers
- 550 people
- Sponsor
- Clinical Center Niš
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Soluble TREM-1 in Diabetes-Associated Cardiovascular Complications
Cardiovascular disease is the leading cause of illness and death among individuals with type 2 diabetes mellitus (T2DM). Chronic low-grade inflammation contributes significantly to blood vessel damage, atherosclerosis, and…
- Conditions
- Type 2 Diabetes Mellitus, Cardiovascular Diseases, Coronary Artery Disease, Heart Failure
- Trial name
- NCT07847112
- Volunteers
- 85 people
- Sponsor
- Assiut University
Metabolism and Nutrition Disorder, Obesity
Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes
This trial is conducted in Africa, Asia, Europe, Oceania, North America and South America. The aim of this clinical trial is to evaluate the potential of liraglutide to induce and maintain weight loss over 56 weeks in obese…
- Trial name
- NCT01272219
- Testing
- liraglutide
- Where
- 226 sites in United States, Argentina and 27 more
- Volunteers
- 3,731 people
- Sponsor
- Novo Nordisk A/S
Heart Failure With Reduced Ejection Fraction (HFrEF), Ventricular Tachycardia (VT)
Metabolomic Profiling in Ischemic and Non-Ischemic Cardiomyopathy Patients With Ventricular Arrhythmias
This single-center prospective observational study aims to evaluate differences in metabolomic pathways between patients with ischemic and non-ischemic cardiomyopathy with reduced left ventricular ejection fraction and documented…
- Conditions
- Heart Failure With Reduced Ejection Fraction (HFrEF), Ventricular Tachycardia (VT), Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy
- Trial name
- MET-CMP (NCT07507539)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Muhammed Heja Geçit
Cardiovascular Diseases
Cardiovascular Disease Population Risk Tool
The purpose of this study is to develop, evaluate, and apply a predictive algorithm for assessing CVD risk in the community setting: the Cardiovascular Disease Population Risk Tool (CVDPoRT).
- Trial name
- CVDPoRT (NCT02267447)
- Volunteers
- 104,219 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Lung Cancer
Observational Study That Will Analyse the Spread and Stratification of Lung Cancer Risk Using Artificial Intelligence
Observational cohort study involving individuals of both sexes with a history of smoking, residing in municipalities in the state of Bahia and attended by the mobile unit, with the aim of evaluating the integration of artificial…
- Trial name
- ANASTASIA (NCT07617636)
- Where
- Brazil
- Volunteers
- 1,500 people
- Sponsor
- AstraZeneca
Syncope
SW-RCT Implementation of Canadian Syncope Risk Score Based Practice Recommendations
Syncope is a common reason for emergency department (ED) presentation. While often benign, some patients have serious and life-threatening underlying causes, both cardiac and non-cardiac, which may or may not be apparent at the…
- Trial name
- NCT04972071
- Testing
- Knowledge translation (KT) of the CSRS based practice recommendations
- Where
- 15 sites in Canada
- Volunteers
- 14,400 people
- Sponsor
- Ottawa Hospital Research Institute
Cardiovascular Diseases, Healthy
"Multifactorial Risk Stratification in Acute and Chronic Cardiovascular Disease"
The aim of this study is to develop risk prediction models for the early detection of high-risk patients with structural, rhythmological or inflammatory cardiovascular diseases.
- Trial name
- riskINN (NCT05472207)
- Where
- 2 sites in Austria
- Volunteers
- 5,000 people
- Sponsor
- Medical University Innsbruck
Chronic Limb-Threatening Ischemia, Surgery-Complications
Use of CPETarm for Risk Stratification of Patients With CLTI
This is a prospective cohort study of patients undergoing surgery for chronic limb threatening ischaemia. Prior to surgery, patients will undergo CardioPulmonary Exercise testing (CPET) using an arm ergometer.
- Trial name
- NCT06404229
- Testing
- CardioPulmonary Exercise Testing
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Manchester
Endometriosis
Preoperative Staging of Endometriosis With MRI
The purpose of the study is to evaluate the value of MRI in preoperative stratification of endometriosis patients needing surgical approach by gynaecologists only or multidisciplinary approach by gynaecologists, urologists or/and…
- Trial name
- IDEAL (NCT01939535)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Solid Tumor, Leukemia
MoleculAr Profiling for Pediatric and Young Adult Cancer Treatment Stratification 2
FMG2025 continues the previous efforts to propose treatment for patients based on the molecular characteristics of their tumor at treatment failure in cancer precision medicine trials within standard of care in France.
- Trial name
- MAPPYACTS2 (NCT05691608)
- Testing
- Solid tumor and CT DNA
- Where
- 29 sites in France
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Idiopathic Pulmonary Fibrosis
Validation of the Risk Stratification Score in Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is characterized by a poor prognosis, with a progressive decline in lung function and a considerable variability in the disease's natural history.
- Trial name
- NCT02632123
- Where
- 2 sites in Canada, Italy
- Volunteers
- 260 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Worsening Chronic Heart Failure, Diabetic Nephropathy
A Study to Learn How Finerenone (BAY94-8862) Moves Into, Through and Out of the Body, How it Affects the Body, and How Safe it is in Adult Participants With Different Degrees of Reduced Liver Function and in Healthy Participants With Similar Age, Weight and Gender Distribution
Researchers are looking for a better way to treat people who have worsening of chronic heart failure, a long-term condition where the heart does not pump blood as well as it should, as well as to treat patients who have diabetic…
- Trial name
- NCT04881994
- Testing
- Finerenone (BAY94-8862)
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Bayer
Carotid Artery Atheroma, Cardiovascular Risk Stratification
Randomized Controlled Trial on Carotid Atherosclerosis Screening in Asymptomatic Smokers and Hypertensive Adults: Prevalence and Impact on Cardiovascular Prevention
Title of the study: Carotid Atherosclerosis Screening: Epidemiological Profile and Preventive Intervention. Objective: The main objective of this study is to characterize and identify the prevalence of carotid atherosclerosis in…
- Trial name
- CAROTID-CARE (NCT06848283)
- Testing
- Carotid ultrasonography
- Volunteers
- 4,780 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Covid19
Risk Stratification of COVID-19 Patients Discharged From the Emergency Department
Risk stratification of COVID-19 patients is essential to define their appropriate treatment setting. So far, available studies have focused on morbidity and mortality prediction in patients admitted to hospital.
- Trial name
- CODED (NCT04629183)
- Testing
- integrated clinical evaluation
- Where
- 7 sites in Italy
- Volunteers
- 742 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Cervical Cancer, Radiotherapy
A Predictive Model for Early Metastasis in Cervical Cancer Patients After Radiotherapy
This study aims to help to screen out appropriate cases for consolidation therapy and more intensive follow up.
- Conditions
- Cervical Cancer, Radiotherapy, Distant Metastasis, Prognostic Model
- Trial name
- NCT06101966
- Testing
- external pelvic beam radiotherapy (EBRT) followed by individualized high-dose-rate intracavitary brachytherapy (HDR-ICBT)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Fujian Cancer Hospital
Overweight or Obesity, Physical Activities
An Innovative Care Model Integrating Mobile Health Support to Promote Weight Management in Adults With Overweight or Obesity
The objective of this clinical trial is to evaluate whether an innovative care model integrating mobile health (mHealth) support improves weight management in adults with overweight or obesity.
- Conditions
- Overweight or Obesity, Physical Activities, Healthy Diet, Weight Change
- Trial name
- NCT06996431
- Testing
- EMA-based weight management intervention, Minimal Intervention
- Where
- 3 sites in Hong Kong
- Volunteers
- 876 people
- Sponsor
- The University of Hong Kong
Fluid Volume Disorder
Risk Stratification and Goal-directed Volume Therapy
It is difficulte to evaluate risk patients and to find the ideal intraoperative volume management. It seems to be that ill patients benefit of a goal directed volume management.
- Trial name
- NCT01456702
- Testing
- risk stratification group
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Charite University, Berlin, Germany
Cerebrovascular Accident
Transient Ischemic Attack (TIA) Triage and Evaluation of Stroke Risk
Transient ischemic attack (TIA) is a transient neurological deficit (speech disturbance, weakness…), caused by temporary occlusion of a brain vessel by a blood clot that leaves no lasting effect.
- Trial name
- NCT01423201
- Where
- 3 sites in United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Stanford University
Ovarian Cancer
CADx - Radiomics to Distinguish the Origin of Ovarian Tumors
In women with an ovarian tumor, it is often unclear whether the tumor is benign or malignant. To differentiate, tumor markers (CA125 and CEA), a transvaginal ultrasound and, depending on the ultrasound image and the CA125…
- Trial name
- CADx (NCT05174377)
- Testing
- CT-scan algorithm
- Where
- 5 sites in Netherlands
- Volunteers
- 600 people
- Sponsor
- Gynaecologisch Oncologisch Centrum Zuid