Clinical trials: Stratification
Crohn Disease (CD), Colitis Ulcerative
Characterization of Colorectal Dysplasic Lesions and Stratification of Their Evolving Risk in Inflammatory Bowel Disease Patients: a Prospective, Observational and Multicenter Study
Inflammatory Bowel Disease (IBD) patients have an increased risk of ColoRectal Cancer (CRC). The cumulative risk of CRC development is estimated at 1% after 10 years of disease progression, 2% after 20 years, and 5% after more…
- Trial name
- IB DYSPLASIA (NCT07719426)
- Volunteers
- 800 people
- Sponsor
- Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Diabetes
RetroMASTER - Retrospective Cohort MRC ABPI STratification and Extreme Response Mechanism in Diabetes
This study will examine extreme responders to second- and third-line Type 2 Diabetes (T2D) therapy using a retrospective approach and patients with slow or fast diabetes progression.
- Trial name
- RetroMASTER (NCT02109978)
- Where
- 3 sites in United Kingdom
- Volunteers
- 562 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Invasive Ventilation
Prediction of PaO2 Values Using the PRoPERLy II Database
Four prospective observational studies of ventilation in critically ill patients were harmonized and pooled.
- Trial name
- PRoPERLy-II (NCT06589427)
- Testing
- Invasive ventilation.
- Where
- Netherlands
- Volunteers
- 8,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Coronary Artery Bypass
A Retrospective Analysis of the Predictive Potential of Pre-operative
Roughly thirty percent of people that undergo open heart surgery get an abnormal heart beat afterwards known as atrial fibrillation (AF).
- Trial name
- NCT00321282
- Testing
- Atrial Fibrillation
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Emory University
Type 2 Diabetes, Diabetes Related Complications
Time-In-Range Based Risk Stratification of Type 2 Diabetes Microvascular Complications
The goal of this observational study is to learn about the role of Time-in-Range to stratify the risk of micro vascular complications in adults with type 2 diabetes. The main questions it aims to answer are: 1.
- Conditions
- Type 2 Diabetes, Diabetes Related Complications, Diabetes; Retinopathy (Manifestation), Diabetes; Neuropathy, Polyneuropathy (Manifestation)
- Trial name
- TRACK2 (NCT05787990)
- Testing
- Diabetes Microvascular Complication Tests
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- Singapore General Hospital
Solid Neoplasms, Non-Small Cell Lung Cancer
PET/CT-Based Intratumoral Heterogeneity and Multimodal Imaging for Tumor Diagnosis and Prognosis
Background \& Rationale: Intratumoral heterogeneity (ITH) is a recognized hallmark and critical driver of therapeutic resistance, rapid disease progression, and poor survival across solid malignancies, notably advanced…
- Trial name
- NCT07906158
- Testing
- This is an observational study with no intervention.
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Shengjing Hospital
Leukemia, Myeloid
ELN 2022 in MENAFC ( Middle Eastern or North Coast of Africa ) Patients With Newly AML
"In daily clinical practice, 2022 ELN guidelines were used to predict response to conventional treatment and to guide the need for allogenic stem cell transplantation.
- Trial name
- NCT06512610
- Testing
- Middle Eastern or North Coast of Africa patients with newly AML
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cardiomyopathy, Hypertrophic
The Chinese Hypertrophic Cardiomyopathy Study(CHCS)
Hypertrophic cardiomyopathy (HCM) is one of the most common inherited cardiac diseases, with a prevalence of ∼0.2%. Sudden cardiac death (SCD), heart failure and stroke are the major poor outcomes of HCM.
- Trial name
- CHCS (NCT02696135)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
Acute Coronary Syndrome, Chest Pain
Cardiac Magnetic Resonance Imaging Strategy for the Management of Patients With Acute Chest Pain and Detectable to Elevated Troponin
The broad, long-term objective is to improve outcomes by optimizing healthcare delivery processes for patients with detectable to elevated serum troponin.
- Trial name
- CMR-IMPACT (NCT01931852)
- Testing
- Cardiac MRI, ACC/AHA Guideline adherent care
- Where
- 4 sites in United States
- Volunteers
- 312 people
- Sponsor
- Wake Forest University Health Sciences
Acute Coronary Syndrome, Non-ST-Elevation Myocardial Infarction
Risk Stratification of Non ST Elevation ACS With Computed Tomographic Angiography (REACT)
The purpose of this project is to examine the effectiveness of computed tomographic angiography (CTA) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS).
- Conditions
- Acute Coronary Syndrome, Non-ST-Elevation Myocardial Infarction, Unstable Angina
- Trial name
- NCT00449826
- Testing
- Computed Tomographic Angiography
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Renal Insufficiency, Acute
Determination of the "Tissue Transit Time" (TTT)
Determination of Tissue Transit Time (TTT) as a parameter with high prognostic value to predict the functional course of the differential renal function and the development of the differential renal function after pyeloplasty
- Trial name
- NCT03311256
- Testing
- Tissue Transit Time
- Where
- 9 sites in Germany, Switzerland
- Volunteers
- 119 people
- Sponsor
- University Hospital Tuebingen
Gastrointestinal Vascular Malformation
the Efficiency of Endoscopic Treatment for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation
Gastrointestinal vascular malformation (GIVM), which is an important cause of acute or chronic gastrointestinal bleeding, consequently is in dire of effective treatment.
- Trial name
- NCT02716545
- Testing
- balloon assisted enteroscopy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Nasopharyngeal Carcinoma
tReatment Individualisation By EBV stratificatiON in Nasopharyngeal Carcinoma: an Umbrella Platform Study (RIBBON-Umbrella)
This is a prospective platform study that will investigate the outcomes of patients with locoregionally-advanced nasopharyngeal carcinoma (LA-NPC) or recurrent-metastatic nasopharyngeal carcinoma (RM-NPC) who are assigned to…
- Trial name
- NCT05517135
- Testing
- Arm 1, Arm 2, Arm 3
- Where
- Singapore
- Volunteers
- 1,000 people
- Sponsor
- National Cancer Centre, Singapore