Clinical trials: Stratification
Gastric Cancer
CT Body Composition Enhances Survival Risk Stratification
Gastric carcinoma remains the fifth most common malignancy and the second leading cause of cancer-related mortality worldwide. For patients with locally advanced disease, standard treatment includes radical gastrectomy followed…
- Trial name
- NCT07109271
- Where
- Taiwan
- Volunteers
- 227 people
- Sponsor
- Chang Gung Memorial Hospital
Neuroblastoma, Ganglioneuroma
Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors Stratification
Surgery plays significant role in treatment of neurogenic tumors, both for benign ganglioneuroma and for high risk neuroblastoma.
- Conditions
- Neuroblastoma, Ganglioneuroma, Ganglioneuroblastoma
- Trial name
- ANLAP-R (NCT06296732)
- Testing
- Duration of surgery intervention
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Chest Pain, Acute Coronary Syndrome
HEART Pathway Implementation
The purpose of this study is to determine the effectiveness of the HEART Pathway, a clinical decision aid for the care of patients with chest pain, in a "real-world" clinical setting.
- Conditions
- Chest Pain, Acute Coronary Syndrome, Chest Pain Atypical Syndrome, Chest Pain Rule Out Myocardial Infarction
- Trial name
- NCT02056964
- Where
- United States
- Volunteers
- 14,717 people
- Sponsor
- Wake Forest University Health Sciences
Perioperative Myocardial Injury
Perioperative Copeptin: Predictive Value and Risk Stratification in Patients Undergoing Major Surgery
Observational cohort study examining the perioperative course of copeptin in patients undergoing elevated-risk surgery.
- Trial name
- NCT02687776
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 517 people
- Sponsor
- University Hospital, Basel, Switzerland
Pregnancy, High Risk
Validation of a Non-invasive Hemoglobin Measurement Device in Pregnancy and Postpartum in Kenya, Pakistan, and Zambia
Accurate, precise, and comparable hemoglobin measurements is of great importance, both for clinical value in diagnosing anemia and ensuring pregnant women receive appropriate treatment.
- Trial name
- NCT05656352
- Testing
- Masimo Total Hemoglobin SpHb® Continuous Non-invasive Hemoglobin Monitoring Device, Complete Blood Count
- Where
- 4 sites in Kenya, Pakistan and 1 more
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- George Washington University
Fatty Liver, NAFLD - Non-Alcoholic Fatty Liver Disease
Detecting Liver Fibrosis in Patients At-risk
The project will establish a research cohort (called STELIR; STEatotisk Liver-risk In Rogaland) based on a biobank with an associated health register.
- Conditions
- Fatty Liver, NAFLD - Non-Alcoholic Fatty Liver Disease, Nash, MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease)
- Trial name
- STELIR (NCT07775638)
- Testing
- Routine study procedure
- Where
- Norway
- Volunteers
- 1,200 people
- Sponsor
- Helse Stavanger HF
Hepotacellular Carcinoma
Multimodal Deep Learning for Postoperative Liver Cancer Risk Stratification and Intervention
This study is for patients with early-stage liver cancer who are planning to have surgery. The goal of this research is to see if a personalized treatment plan, guided by a computer model (an artificial intelligence tool), can…
- Trial name
- NCT07282184
- Testing
- Neoadjuvant HAIC + Lenvatinib + PD-1 Inhibitor, Curative Liver Resection, Multimodal AI Risk Stratification
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Tongji Hospital
Stroke, Cardiac Disease
Multifactorial Risk Stratification in Stroke Patients With Cardiac Disease
Prospective registry for multifactorial risk factor assessment, enrolling consecutive ischemic stroke/transient ischemic attack patients with structural, inflammatory, or arrhythmogenic cardiac disease, who are admitted to our…
- Trial name
- NCT04352790
- Volunteers
- 878 people
- Sponsor
- University Hospital Tuebingen
Cardiovascular Primary Prevention
Cardiovascular Risk Stratification of Ambulatory Patients in Primary Prevention
This is an observational, cross-sectional, national multicenter study, trying to obtain local data about the global cardiovascular risk profile of patients attending ambulatory offices of general practitioners and cardiologists.
- Trial name
- RISK (NCT01889030)
- Where
- Argentina
- Volunteers
- 516 people
- Sponsor
- AstraZeneca
Lung Cancer Screening
LUNG-07: Advancing Precision-Based Lung Cancer Screening: Implementation, AI-Guided Risk Stratification, and Biomarker Integration (CREST AI)
This research study aims to investigate methods for enhancing lung cancer screening. The study will investigate whether an artificial intelligence (AI) tool, known as Sybil, can aid in predicting the risk of lung cancer.
- Trial name
- NCT07408531
- Testing
- Sybil Artificial Intelligence (AI) screening
- Where
- 2 sites in United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
COVID, Coronavirus Infection
Point Of Care UltraSonography for Risk-stratification of COVID-19 Patients
COVID-19 pandemic has developed worldwide in less than 4 months. While most patients have a mild or uncomplicated disease (80%), approximately 15% need hospital care and 5% intensive care.
- Trial name
- POCUSCO (NCT04338100)
- Testing
- Follow-up at 14 days
- Where
- 11 sites in Belgium, France
- Volunteers
- 307 people
- Sponsor
- University Hospital, Angers
Colorectal Cancer
Evaluation of Somatic Mutation Spectrum as Biomarker for Survival Outcome in Chinese CRC
By analyse the tissue/blood variant spectrum model using NGS, the present clinical trial aims to elucidate the genetic basis of CRC in Chinese; to establish of CRC genetic map in Chinese patients; to identification new genetic…
- Trial name
- NCT04228614
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Sun Yat-sen University
Stroke
AI-assisted Continuous Stratification in Neurorehabilitation of Stroke Using Personalized Digital Twins
The goal of this clinical trial is to learn if a rehabilitation application on a smartphone, an app, can be used by adults who have had a stroke.
- Trial name
- STRATIF-AI (NCT07488143)
- Testing
- Smartphone rehabilitation application "app"
- Volunteers
- 30 people
- Sponsor
- University of Leeds
Heart Failure, Cardiomyopathies
Validation of the Prognostic Impact of a Retinal Photograph-based Cardiovascular Disease Risk Stratification System in de Novo HFrEF
"Despite significant advances in pharmacologic and device-based therapies, heart failure (HF) remains a major public health burden, with persistently high rates of hospitalization, impaired quality of life, and excess…
- Conditions
- Heart Failure, Cardiomyopathies, Retinal Photograph, Deep Learning
- Trial name
- NCT06978998
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Multiple Organ Failure
Feasibility Study of MicroKine Dx System in Critically-ill Pediatric Patients.
This study will enroll approximately 25 pediatric patients to assess the performance and real-world feasibility of multi-biomarker based prognostic and predictive algorithms to aid in the clinical management of pediatric…
- Trial name
- NCT04295278
- Testing
- MicroKine Dx system
- Volunteers
- 25 people
- Sponsor
- PreDxion Bio, Inc.
Psoriatic Arthritis, Osteoarthitis
CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry
CARTIZ is a prospective observational clinical registry of adults in Mexico receiving tirzepatide (a dual GLP-1/GIP receptor agonist) under an independent clinical indication - typically type 2 diabetes, insulin resistance…
- Conditions
- Psoriatic Arthritis, Osteoarthitis, Knee, Diabetes (DM)
- Trial name
- CARTIZ (NCT07567378)
- Testing
- Tirzepatide
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- JULIO GRANADOS MONTIEL
Stroke, Acute
Validation of Aspiration Risk Assessment in Stroke Units
The purpose of the study is to test the validity of a modified Daniels swallow test. The original test serves as reference method, the swallow endoscopy (FEES) as "gold standard".
- Trial name
- ARAS (NCT06162910)
- Testing
- Daniels Water Swallow Test, Flexible Endoscopic Evaluation of Swallowing
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Giessen
Type2diabetes, Heart Failure
N-terminal Pro-B-type Natriuretic Peptide (NT-proBNP) in Type 2 Diabetes Mellitus
More than 400 million people have type 2 diabetes (T2D) globally, and the burden of diabetes-related cardiovascular complications is increasing.
- Conditions
- Type2diabetes, Heart Failure, Cardiovascular Complication
- Trial name
- PISCES (NCT05745090)
- Where
- Singapore
- Volunteers
- 1,200 people
- Sponsor
- Singapore General Hospital
Acute Coronary Syndrome, Chest Pain
Efficacy Evaluation of the HEART Pathway in Emergency Department Patients With Acute Chest Pain
Our research will examine a chest pain care strategy, called the HEART pathway, which is designed to correctly identify Emergency Department patients at high-risk for cardiovascular events, likely to benefit from further testing…
- Trial name
- HEART Pathway (NCT01665521)
- Testing
- HEART Pathway
- Where
- United States
- Volunteers
- 282 people
- Sponsor
- Wake Forest University Health Sciences
Copd Exacerbation Acute, Readmission
Identification of Patients Admitted With COPD Exacerbations and Predicting Readmission Risk Using Machine Learning
Patients with Chronic Obstructive Pulmonary Disease (COPD) who are admitted to hospital are at high risk of readmission. While therapies have improved and there are evidence-based guidelines to reduce readmissions, there are…
- Conditions
- Copd Exacerbation Acute, Readmission, Machine Learning, Natural Language Processing
- Trial name
- NCT04192175
- Where
- Canada
- Volunteers
- 65,000 people
- Sponsor
- University Health Network, Toronto