Clinical trials: Stress
Metabolic Syndrome X, Overweight
Chloroquine to Treat People With Metabolic Syndrome Aim2 (ARCH-MS)
Metabolic syndrome consists of a group of co-occuring conditions that increase an individual's risk of developing heart disease, stroke, and diabetes.
- Conditions
- Metabolic Syndrome X, Overweight, Hypertension, Dyslipidemias
- Trial name
- ARCH-MS (NCT00455325)
- Testing
- Active Comparator: Second Intervention (3 weeks), Active Comparator: Third Intervention (3 weeks), Active Comparator: Fourth Intervention (3 weeks)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Washington University School of Medicine
Asthma
Breathe With Ease: A Unique Approach to Managing Stress (BEAMS)
Uncontrolled asthma in at-risk youth responds well to guideline-based therapy when patients remain adherent to their management plans.
- Trial name
- NCT02374138
- Testing
- Parental stress management, Usual Care
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- Stephen J. Teach, MD, MPH
Urinary Incontinence, Stress, Urinary Incontinence, Urge
Group Learning Achieves Decreased Incidents of Lower Urinary Symptoms
This three-site randomized controlled trial compares the effectiveness and cost-effectiveness of a group-administered behavioral treatment program to no treatment.
- Trial name
- Gladiolus (NCT02001714)
- Testing
- Group Behavioral Treatment
- Where
- 4 sites in United States
- Volunteers
- 463 people
- Sponsor
- Ananias Diokno
Healthy Pregnant Women
Effect of Omega-3 Supplementation During Pregnancy on Regulation of Stress
This will be the first study of the effect of essential fatty acid supplementation in pregnant women living in inner-city poverty on the stress response system during pregnancy.
- Trial name
- NAPS (NCT01158976)
- Testing
- Docosahexanoic Acid
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Professional Fulfillment, Professional Identity Formation
A Professional Development Programme (ProDeveloP) for Newly Graduated Nurses
This clinical study aims to implement and evaluate a professional development programme (ProDeveloP) designed to facilitate the transition of newly graduated nurses (NGNs) into their new roles.
- Conditions
- Professional Fulfillment, Professional Identity Formation, Professional Quality of Life, Support Program
- Trial name
- NCT06742047
- Testing
- Professional development programme
- Where
- Sweden
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Mälardalen University
Oxidative Stress
The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels
Glutathione is a powerful protective substance found within every cell in the body. It has been shown that glutathione levels go down as a person gets older, which makes a person more likely to get heart disease, high blood sugar…
- Trial name
- NCT01251315
- Testing
- N Acetyl cysteine, 600mg (low dose), Proimmune 200 (FT061452) 3000mg low dose, N Acetyl cysteine, 1200mg (high dose)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Schizophrenia, Schizoaffective Disorder
Withania Somnifera: an Immunomodulator and Anti-inflammatory Agent for Schizophrenia
Withania somnifera (WSE; Ashwagandha in Ayurveda) extracts have been used as an adaptogen or to build resistance to stress or diseases in indigenous medical systems in India for centuries.
- Trial name
- NCT01793935
- Testing
- Sensoril®
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- K.N. Roy Chengappa
Stress Disorders, Post-Traumatic
Wildlife and Wellbeing: An Animal-Assisted Intervention for Veterans With PTSD
This study investigates a novel approach to animal-assisted interventions through a series of wildlife immersion activities (wildlife observation, wildlife rehabilitation and bird feeding/watching) for veterans who have suffered…
- Trial name
- NCT04116489
- Testing
- Forest walk, Wildlife rehabilitation, Wildlife sanctuary observation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Massachusetts, Worcester
PTSD, Cardiac Arrest
Acceptance and Mindfulness Based Exposure Therapy for Survivors of Cardiac Arrest
The primary goal of this uncontrolled pilot trial is to examine feasibility, acceptability, safety, and preliminary efficacy of a new behavioral treatment for survivors of sudden cardiac arrest with clinically elevated symptoms…
- Trial name
- AMBET (NCT04596891)
- Testing
- Psychotherapy
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Emotional Distress, Burnout, Professional
A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers
This is a pilot randomized waitlist control trial assessing if the feasibility of using a mobile mindfulness app to treat emotional distress and burnout amongst nurses taking care of COVID-19 patients.
- Conditions
- Emotional Distress, Burnout, Professional, Stress, Job, Anxiety
- Trial name
- LIFT-HCW (NCT04816708)
- Testing
- LIFT Mindfulness
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Duke University
Body Temperature Changes
Cooling Vest May Reduce Heat Stress During Surgery
The investigators will propose a randomized cross-over trial using a uniform and strongly balanced 4-period design in which will include four operations for each surgeon.
- Trial name
- NCT04511208
- Testing
- Cooling Vest, Without cooling vest
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Leukemia, Lymphoma
Mindfulness Interventions to Improve Health Activation, Coping, and Stress Among Childhood Cancer Survivors
This study will explore feasibility and acceptability of using a daily mobile mindfulness app to cope with stress. In addition, feasibility of digital health data collection procedures including wrist-worn devices and ecological…
- Conditions
- Leukemia, Lymphoma, Childhood Cancer
- Trial name
- NCT06053268
- Testing
- Headspace
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- St. Jude Children's Research Hospital
Coronary Artery Disease (CAD)
A Study of Regadenoson in Subjects Undergoing Stress Myocardial Perfusion Imaging (MPI) Using Multidetector Computed Tomography (MDCT) Compared to Single Photon Emission Computed Tomography (SPECT)
The purpose of this study is to compare Multidetector Computed Tomography (MDCT) and Single Photon Emission Computed Tomography (SPECT) stress myocardial perfusion imaging (MPI) with regadenoson in order to detect the presence or…
- Trial name
- NCT01334918
- Testing
- regadenoson, technetium Tc99m sestamibi /technetium Tc99m tetrafosmin, Contrast
- Where
- 11 sites in United States
- Volunteers
- 124 people
- Sponsor
- Astellas Pharma Inc
Tobacco Dependence, PTSD
Behavioral Activation for Smoking Cessation in PTSD
The purpose of this study is to examine whether behavioral activation as an adjuvant to standard smoking cessation treatment improves smoking cessation outcomes among veterans with PTSD relative to a comparably intense…
- Trial name
- NCT01995123
- Testing
- Behavioral Activation Therapy, Health and Smoking Education, Standard Smoking Cessation Therapy
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment, Caregiver Burnout
Improving Physical Activity With Cognitive Impairment
Individuals with mild cognitive impairment are often physically inactive and at risk for progressing to dementia. Physical inactivity is considered a modifiable risk factor for dementia.
- Trial name
- NCT05370118
- Testing
- Telerehabilitation physical activity behavioral (TPAB) intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Creighton University
Heart Diseases, Stroke
The HARMONY Study: A Intervention to Reduce Cardiometabolic Risk in African American Women
This study will test whether a culturally-tailored nutrition and exercise intervention designed for African-American women will lead to sustained improvements in exercise and healthy eating through improvements in self-management…
- Conditions
- Heart Diseases, Stroke, Pre-diabetes, Hypertension
- Trial name
- NCT04705779
- Testing
- HARMONY, Nutrition and Exercise Education (NEEW)
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of North Carolina, Chapel Hill
Stress Urinary Incontinence
Pippa Pessary Study (Clinical Trial)
This is an open label, interventional, single arm, multi-clinic study where each adult female participant with stress urinary incontinence (SUI) serves as her own control (vaginal pessary use vs. no vaginal pessary).
- Trial name
- NCT05611970
- Testing
- Vaginal pessary
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Liv Labs Inc.
Post Traumatic Stress Disorder, Mild Traumatic Brain Injury, Concussion
Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI
One of the most pressing concerns within the VA currently is the provision of interventions that address the cognitive as well as emotional problems faced by Veterans with concurrent mild TBI and PTSD.
- Trial name
- NCT01921179
- Testing
- GOALS (Goal-Oriented Attentional Regulation), EDU (Brain Health Education)
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Alcohol Use
CBT Texts for PTSD & Hazardous Drinking (Project Better)
The research study seeks to refine and test a brief, self-directed, intervention for individuals from the general public with PTSD and co-occurring HD that can be delivered via text-messaging.
- Trial name
- NCT05372042
- Testing
- CBT Text Messages
- Where
- United States
- Volunteers
- 505 people
- Sponsor
- University of Washington
Hyperglycemia
Sitagliptin in Non-Diabetic Patients Undergoing General Surgery
The purpose of this study is to compare sitagliptin with a placebo for the prevention of high glucose after general surgery.
- Trial name
- NCT02741687
- Testing
- Sitagliptin, Supplemental insulin (insulin lispro), Supplemental insulin (insulin aspart)
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Emory University
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