Clinical trials: Stress Biomarkers
Gout
Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout
There is a mounting and clear association between hyperuricaemia, gout and the presence of traditional cardiovascular (CV) risk factors and CV event-equivalent conditions such as chronic kidney disease, metabolic syndrome, and…
- Trial name
- FORWARD (NCT02500641)
- Testing
- Febuxostat 80/120mg/day, Allopurinol 100 up to 600mg/day, Colchicine
- Where
- 26 sites in Germany, Italy and 4 more
- Volunteers
- 196 people
- Sponsor
- Menarini International Operations Luxembourg SA
Post Traumatic Stress Disorder
A Pilot Dose-Response Biomarker Study of Brexpiprazole Treatment in PTSD
Determine if brexpiprazole treatment will be associated with a dose-dependent reduction in resting pupil diameter as a reflection of locus coeruleus (LC) norepinephrine (NE) neuron target engagement in a group of subjects with…
- Trial name
- NCT02934932
- Testing
- Brexpiprazole
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Duke University
Oxidative Stress, Inflammation
Organic Diet Intervention in Primary School Children
The study aims to evaluate the hypothesized benefits of a systematic organic diet for children, over those of a conventional diet.
- Trial name
- ORGANIKO (NCT02998203)
- Testing
- Organic diet
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Cyprus University of Technology
Osteoarthritis
A Biomarker Stress Test for Detection of Early Osteoarthritis
Veterans have much higher risk of osteoarthritis (OA) then the general population. Knee OA is common among Veterans and is a leading cause of disability.
- Trial name
- NCT02593864
- Testing
- Variable-Stiffness Shoe
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- VA Palo Alto Health Care System
Posttraumatic Stress Disorder
Neurosteroids in PTSD - Biomarkers to Therapeutics
The purpose of this research is to determine if a study medication called Dehydroepiandrosterone (DHEA) helps to reduce PTSD symptoms in OEF/OIF/OND Veterans.
- Trial name
- NCT03491007
- Testing
- DHEA
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development