Clinical trials: Stress Disorder
Depression, Postpartum, Anxiety Disorders
Inhaled Oxytocin and HPA Axis Reactivity
Mothers who were enrolled in the Mood, Mother and Infant study will be eligible to participate in the 6-year follow-up maternal visit.
- Conditions
- Depression, Postpartum, Anxiety Disorders, Stress, Psychological
- Trial name
- NCT03593473
- Testing
- Intranasal Oxytocin
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of North Carolina, Chapel Hill
Alzheimer's Disease, Oxidative Stress
Fish Oil and Alpha Lipoic Acid in Treating Alzheimer's Disease
The purpose of this study is to determine the effect of fish oil and the antioxidant alpha lipoic acid on factors in the blood that are associated with the progression of Alzheimer's Disease (AD).
- Conditions
- Alzheimer's Disease, Oxidative Stress, Dementia, Hyperlipidemia
- Trial name
- NCT00090402
- Testing
- Fish Oil, Lipoic Acid
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Oregon Health and Science University
Prolapse, Urinary Incontinence
Long-term Effectiveness of Abdominal Sacrocolpopexy for the Treatment of Pelvic Organ Prolapse
The Colpopexy and Urinary Reduction Effort (CARE) trial is a research study designed to evaluate whether the addition of a second surgical procedure in addition to a procedure for female pelvic organ prolapse (POP) affects the…
- Trial name
- E-CARE (NCT00099372)
- Where
- 8 sites in United States
- Volunteers
- 215 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Cancer, Quality of Life
The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer
Multi-Site Randomized Controlled Trial testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults with Advanced Cancer
- Conditions
- Cancer, Quality of Life, Anxiety, Depression
- Trial name
- PRISM-AC (NCT03668223)
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- 5 sites in United States
- Volunteers
- 269 people
- Sponsor
- Dana-Farber Cancer Institute
Post-Traumatic Stress Disorder, Depression
Evaluation of Two Community-based Mental Health Interventions for Violence-Displaced Afro-Descendants in Colombia.
This study is a community prevention randomized trial with three parallel groups: two intervention groups and one control group in Buenaventura and Quibdó.
- Conditions
- Post-Traumatic Stress Disorder, Depression, Anxiety, Violence
- Trial name
- ACOPLE (NCT01856673)
- Testing
- Common Elements Treatment Approach, Narrative Community Group Therapy, Standby group
- Where
- 2 sites in Colombia
- Volunteers
- 521 people
- Sponsor
- Universidad del Valle, Colombia
Cardiovascular Disease (CVD), Hypertension
Veteran Peer Coaches Optimizing and Advancing Cardiac Health
The purpose of this study is to test if having a Veteran peer health coach will improve blood pressure control among Veterans with high blood pressure and at least one other Cardiovascular disease (CVD) risk factor.
- Conditions
- Cardiovascular Disease (CVD), Hypertension, Hyperlipemia, Obesity
- Trial name
- Vet-COACH (NCT02697422)
- Testing
- Community-based peer health coach intervention
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- VA Office of Research and Development
Alcoholism, Stress Disorders, Post-Traumatic
Reducing Alcohol Use & Post-traumatic Stress Disorder (PTSD) With Cognitive Restructuring & Experiential Acceptance
The purpose of this study is to determine whether an experiential acceptance therapy intervention is effective in the treatment of alcohol dependency and post-traumatic stress disorder (PTSD) symptoms in individuals who suffer…
- Trial name
- COPE (NCT00760994)
- Testing
- Experiential acceptance, Cognitive restructuring, No-intervention control: Nutrition information
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Stress Disorders, Post-Traumatic, Brain Injuries, Traumatic
Interventions for Parent Caregivers of Injured Military/Veteran Personnel
This randomized clinical trial will test a behavioral caregiving intervention that has been used successfully for dementia and spinal cord injury caregivers to provide services to stressed and burdened parent caregivers of post…
- Trial name
- NCT03309046
- Testing
- REACH Individual Session, Education Webinar
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Memphis VA Medical Center
Posttraumatic Stress Disorder
Imaginal Exposure & D-Cycloserine (DCS) for Posttraumatic Stress Disorder (PTSD)
This study proposes to evaluate the effects of D-cycloserine (DCS) combined with cognitive-behavioral treatment with exposure therapy in a sample of patients who developed posttraumatic stress disorder (PTSD) as a consequence of…
- Trial name
- NCT00875342
- Testing
- DCS
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Weill Medical College of Cornell University
PTSD
Dexamethasone Plus Virtual Reality Exposure Therapy for PTSD
Evidence from preliminary studies suggests that people with PTSD have heightened fear responses and that cortisol suppression reduces this heightened fear.
- Trial name
- Dex (NCT01965366)
- Testing
- Virtual reality exposure therapy, 0.5 mg DEX
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Emory University
Stress Disorders, Post-Traumatic
Breathing Meditation Intervention for Post Traumatic Stress Disorder
Post traumatic stress disorder (PTSD) is a condition that develops as a result of exposure to a traumatic event. The purpose of this study is to determine whether a breathing meditation technique (Sudarshan Kriya Yoga; SKY)…
- Trial name
- NCT02366403
- Testing
- SKY meditation, CPT-C
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- VA Office of Research and Development
Diastolic Dysfunction
Early Diagnosis of Diastolic Dysfunction and Reliability of DSE in Detecting Stress Diastolic Dysfunction
The heart becoming "stiff" due to increased fibrous tissue or decreased elasticity of the heart tissue is one of the earliest changes caused by heart failure.
- Trial name
- NCT00998205
- Testing
- Dobutamine stress echo (DSE), Atropine bolus
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Infant of Diabetic Mother, Oxidative Stress
NAC +taVNS in IDM Who Are Poor Oral Feeders
Infants of diabetic mothers who are failing to learn oral feeding by term age equivalence have greater CNS oxidative stress, which interact to predict poor neuroplasticity response to transcutaneous vagus nerve stimulation paired…
- Conditions
- Infant of Diabetic Mother, Oxidative Stress, Vagus Nerve Stimulation, Feeding Disorders
- Trial name
- NCT04632069
- Testing
- N acetyl cysteine + vagus nerve stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Medical University of South Carolina
Depression, Quality of Life
Internet and Telephone Support Intervention for Stroke Caregivers
This study will test a problem-solving and support intervention for caregivers of veterans with stroke. The investigators will assign caregivers to one for four groups: 4-session intervention, 8-session intervention, attention…
- Conditions
- Depression, Quality of Life, Recovery of Function, Self Efficacy
- Trial name
- NCT04348851
- Testing
- Caregiver problem-solving, Attention Control
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Smoking Cessation
Supplemental Nicotine Administration for Smoking Cessation in Posttraumatic Stress Disorder (PTSD)
The investigators propose to evaluate the relationship between PTSD, mood, craving and withdrawal symptoms and factors associated with relapse in the context of a randomized clinical smoking cessation trial.
- Trial name
- NCT01055886
- Testing
- nicotine patch
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Duke University
Kidney Failure, Chronic
Exercise Intolerance in Renal Failure
Patients with chronic kidney disease have profound exercise intolerance which contributes to an increased risk of cardiovascular disease.
- Trial name
- EIRF (NCT01356966)
- Testing
- Tetrahydrobiopterin, Folate
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Emory University
Posttraumatic Stress Disorder
Teaching Loved Ones to Help Veterans Optimize Their PTSD Care and Healing
PTSD occurs in as many as 17% of US military Veterans and is associated with a host of negative, long-term consequences to the individual, their families, and society at large.
- Trial name
- NCT04241094
- Testing
- Loved one assisted treatment
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Opioid-use Disorder
Cannabidiol on Reward- and Stress-related Neurocognitive Processes in Individuals With Opioid Use Disorder
The purpose of this study is to determine the impact of cannabidiol on reward- and stress-related neurocognitive processes among individuals with opioid use disorder on buprenorphine or methadone treatment.
- Trial name
- NCT04982029
- Testing
- Cannabidiol 100 MG/ML [Epidiolex]
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Brigham and Women's Hospital
Older Adults, Healthy Aging
danceSing Care Evaluation: Testing the Effectiveness
This pilot randomised controlled trial aims to compare the effectiveness of a 12-week music and movement intervention in older adults in care homes compared to a waitlist control group.
- Conditions
- Older Adults, Healthy Aging, Aging, Quality of Life
- Trial name
- NCT05601102
- Testing
- danceSing Care
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Posttraumatic Stress Disorder
Evaluating a Novel Working Memory Training Program to Decrease Symptoms of PTSD
The study is designed to evaluate the effect of a novel computer training program on PTSD.
- Trial name
- NCT02139137
- Testing
- Computerized Cognitive Training - active
- Volunteers
- 47 people
- Sponsor
- Rick Gulizia
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