Clinical trials: Stress Disorder
Cardiorespiratory Failure
Mobile Coping Skills Training to Improve Cardiorespiratory Failure Survivors' Psychological Distress
This is a pilot randomized clinical trial involving adult survivors of cardiorespiratory failure treated in intensive care units (ICUs) that is designed to test the acceptability, feasibility, and clinical impact of a coping…
- Trial name
- Blueprint (NCT04329702)
- Testing
- Coping skills training mobile app with call from CST therapist, Coping skills training mobile app only
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Duke University
Posttraumatic Stress Disorder
Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy Trial
This study will consist of a single session of MDMA-assisted therapy with a full dose of MDMA for people who took part in a study of MDMA-assisted therapy in people with posttraumatic stress disorder (PTSD) whose PTSD symptoms…
- Trial name
- NCT01458327
- Testing
- Midomafetamine, Therapy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Resilient Pharmaceuticals
Urinary Incontinence, Stress
A Pre-Market Study of the American Medical Systems (AMS) Transobturator Male Sling System for the Treatment of Male Stress Urinary Incontinence
The purpose of this study is to obtain surgical technique data for use in physician education and training and to collect early clinical outcomes data for future publication.
- Trial name
- AMS051 (NCT00904969)
- Testing
- The AMS Male Transobturator Sling System, AdVance Male Sling
- Where
- 11 sites in United States, Canada
- Volunteers
- 55 people
- Sponsor
- American Medical Systems
Stress, Anxiety
The Effects of Smell on Mood and Physical Responses
The purpose of this study is to examine the body's response to relaxing and stimulating fragrances commonly used in aromatherapy.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- NCT00097253
- Testing
- Exposure to relaxant and stimulant odors
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
PTSD
Pilot Evaluation of AboutFace: Novel Peer Education Resource for Veterans
The purpose of this study is to evaluate the AboutFace peer education website for the purpose of reducing stigma and improving attitudes toward seeking mental health services among Veterans.
- Trial name
- NCT02486692
- Testing
- AboutFace Website
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Adrenocortical Carcinoma, Peritoneal Carcinomatosis
Surgery and Heated Chemotherapy for Adrenocortical Carcinoma
Background: Adrenocortical carcinoma (ACC) is a rare tumor of the adrenal gland. Few people who develop this disease live more than 5 years after being diagnosed.
- Trial name
- NCT01833832
- Testing
- Cisplatin, Cytoreductive surgery, sodium thiosulfate
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Cancer Institute (NCI)
Aging, Vascular Endothelium
Vascular Dysfunction During Physical Inactivity
Prolonged periods of reduced activity are associated with decreased vascular function and muscle atrophy. Physical inactivity due to a sedentary lifestyle or acute hospitalization is also associated with impaired recovery…
- Conditions
- Aging, Vascular Endothelium, Skeletal Muscle
- Trial name
- NCT04872998
- Testing
- Step Count Reduction
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Utah
Stroke
Mindfulness-Based Stress Reduction to Improve Neuropsychological Functioning in Acquired Brain Injury
Thousands of Veterans suffer a stroke every year, and these individuals often suffer emotional and cognitive changes that negatively affect their quality of life as well as their ability to recover.
- Trial name
- NCT03969563
- Testing
- Mindfulness-based Stress Reduction, Brain Health Education
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- VA Office of Research and Development
Generalized Anxiety Disorder, Seroquel XR
Generalized Anxiety and Seroquel
The 12 week clinical trial of Seroquel in Generalized Anxiety Disorder (GAD) patients will be combined with fMRI experiments.
- Trial name
- GAD (NCT01066143)
- Testing
- Seroquel XR
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Posttraumatic Stress Disorder
Suvorexant and Sleep's Benefits to Therapeutic Exposure for Posttraumatic Stress Disorder
The purpose of this study is to examine effects of blocking the orexin system with suvorexant after exposure-based intervention for posttraumatic stress disorder (PTSD) on sleep, PTSD symptoms, and intersession habituation.
- Trial name
- NCT02849548
- Testing
- suvorexant
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Howard University
Anxiety Disorders, Mood Disorders
Efficacy of Sleep Interventions for Posttraumatic Stress Disorder (PTSD)
The purpose of this research study is to evaluate and compare the effects of experimental treatments aimed at improving insomnia and nightmares in men and women military veterans between the ages of 18 and 60 years old, and who…
- Conditions
- Anxiety Disorders, Mood Disorders, Insomnia, Nightmares
- Trial name
- EASI-P (NCT00393874)
- Testing
- Behavioral Sleep Intervention, Prazosin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Substance Use Disorders, Post Traumatic Stress Disorder
A Trauma Informed Adaptation of Mindfulness-Based Relapse Prevention for Women in Substance Use Treatment
More than 90% of women in substance use treatment report history of physical and/or sexual trauma, and up to 60% meet criteria for both substance use disorder (SUD) and Post Traumatic Stress Disorder (PTSD).
- Trial name
- NCT03505749
- Testing
- Trauma Informed Mindfulness-Based Relapse Prevention, Treatment As Usual (TAU)
- Where
- 5 sites in United States
- Volunteers
- 96 people
- Sponsor
- Pacific University
Stress, Pain
Evaluation of the Surgical Pleth Index During Spinal and General Anesthesia
The Surgical Pleth index (SPI) has been introduced as a non invasive tool to "measure" stress and pain during surgery. Preliminary studies were performed in patients under general anaesthesia with propofol and remifentanil.
- Trial name
- NCT00789438
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- University Hospital Schleswig-Holstein
Anxiety Symptoms, Depressive Symptoms
Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
The goal of the project is to test whether a single-session intervention teaching incremental theories of personality, or the belief that one's personality is malleable, can strengthen recovery from social stress and reduce the…
- Trial name
- NCT03132298
- Testing
- Implicit Theories of Personality Program, Control Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Harvard University
HIV
Effects of Mindfulness Training on Chronic Inflammation in HIV-Infected Adults
By 2015 half of the people living with HIV infection in the U.S. are estimated be over the age of 50, and this cohort of patients with well-controlled plasma viremia is aging at a more rapid pace than their non-HIV peers.
- Trial name
- NCT02626949
- Testing
- MBSR Course, HEP Course
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Post Traumatic Stress Disorder
Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)
This study will examine the effects of psychotherapy as treatment for PTSD, and specifically how brain activity and brain connectivity is affected by Mindfulness Based Cognitive Therapy (MBCT) and an active mind-body comparison…
- Trial name
- NCT03874793
- Testing
- Mindfulness-Based Cognitive Therapy, Muscle Relaxation Therapy
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- Ohio State University
Stress Urinary Incontinence
Time Interval Between TVT and First Void (TIBT) Study
The primary aim of this study is to compare, in women undergoing tension-free vaginal tape (TVT) insertion under sedation and local anaesthetic infiltration, the time interval of first void following surgery between a group of…
- Trial name
- TIBT (NCT02443987)
- Testing
- Intravenous fluid
- Where
- 2 sites in United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Post-Traumatic Stress Disorder, Alcohol Use Disorder
Resolving Psychological Stress
The investigators have developed a mobile app called Resolving Psychological Stress (REPS) to help alleviate symptoms of PTSD. The app will administer threat-related attention bias modification to individuals who have both a…
- Trial name
- RePS (NCT03996876)
- Testing
- RePS (Resolving Psychological Stress) - Threat ABM Training, RePS (Resolving Psychological Stress) - Neutral Attention Training
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Francisco
Chronic Pain, PTSD
Management of Chronic Pain and PTSD in Gulf War Veterans With tDCS+Prolonged Exposure
Gulf War Veterans (a DoD/VA defined service era corresponding to the first Gulf War under operations Desert Storm and Desert Shield 1990-1991), especially those who present with Post-Traumatic Stress Disorder (PTSD), are…
- Trial name
- NCT04236284
- Testing
- Home-based tDCS, Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Posttraumatic Stress Disorder
Telemedicine Outreach for Post Traumatic Stress in CBOCs
The purpose of this study is improved outcomes for veterans with Post Traumatic Stress Disorder (PTSD) treated in small VA Community Based Outpatient Clinics (CBOCs).
- Trial name
- TOP (NCT00821678)
- Testing
- Telemedicine Outreach for PTSD
- Where
- 3 sites in United States
- Volunteers
- 265 people
- Sponsor
- VA Office of Research and Development
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