Clinical trials: Stress Disorders
Stress, Anxiety
Cereset Research Long-Term Healthcare Worker Study
Randomized, controlled study of long-term maintenance Cereset Research after an initial 4-session intervention bolus versus usual care control following an initial 4-session intervention bolus.
- Conditions
- Stress, Anxiety, Autonomic Dysregulation, Acoustic Stimulation
- Trial name
- LT-HW (NCT05994261)
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Sleep Apnea
The Role of Oxidative Stress in the Cardiovascular Consequences of Sleep Apnea
Obstructive Sleep Apnea (OSA) is the most common sleep disorder affecting up to 9-24 percent of middle aged adults, and is becoming increasingly implicated in the pathogenesis of hypertension, and other cardiovascular disorders.
- Trial name
- NCT00701441
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Rami Khayat
Posttraumatic Stress Disorder
Nepicastat for Posttraumatic Stress Disorder (PTSD) in OIF/OEF Veterans
This study proposes a multi-site, randomized, double-blind, placebo-controlled clinical trial of the dopamine-ß-hydroxylase (DBH) inhibitor, nepicastat, for the treatment of posttraumatic stress disorder (PTSD) in outpatients who…
- Trial name
- Nepicastat (NCT00659230)
- Testing
- Nepicastat
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tuscaloosa Research & Education Advancement Corporation
Alcohol Dependence, PTSD
Neuromodulation of Trauma Memories in PTSD & Alcohol Dependence
The purpose of this study is to examine the effect of propranolol versus placebo on craving, distress and cue reactivity to trauma and alcohol cues.
- Trial name
- NCT01055171
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Sexual Dysfunction, Stress Incontinence
A Study to Measure the Degree and Effectiveness of the Various vSculpt Operating Modes
A pilot study to determine the degree and effectiveness of the various modes of vSculpt, an over-the-counter "OTC" medical device, on enhanced genital blood flow and improvement in quality of life in menopausal women who suffer…
- Trial name
- NCT02856490
- Testing
- vSculpt, InTone
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Joylux, Inc.
Posttraumatic Stress Disorder, Substance Use Disorders
Treating Violence-related PTSD and Substance Risk in Low-income, Urban Adolescents
This project will provide initial feasibility and efficacy data for the implementation of Narrative Exposure Therapy (NET) to urban, at-risk youth.
- Trial name
- POWER-NET (NCT03737383)
- Testing
- Narrative Exposure Therapy
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Posttraumatic Stress Disorder
MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD
The goal of this clinical trial is to learn if cognitive-behavioral conjoint therapy (CBCT) in combination with MDMA-assisted therapy is safe and effective in people with chronic PTSD and their partners.
- Trial name
- NCT02876172
- Testing
- MDMA, CBCT, Therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Resilient Pharmaceuticals
Hypertension
Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients
The purpose of this study is to determine if Nebivolol improves microvascular perfusion in skeletal muscle during exercise in hypertensive patients and whether this improvement is accompanied by reduction in vascular oxidative…
- Trial name
- NCT01501929
- Testing
- Metoprolol succinate, Nebivolol, Non-invasive measurement of Cardiac Output (CO)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Depression, Stress Disorders, Post-Traumatic
Effectiveness and Implementation of eScreening in Post 9/11 Transition Programs
Electronic screening is effective for timely detection of, and intervention for, suicidal ideation and other mental health symptoms.
- Conditions
- Depression, Stress Disorders, Post-Traumatic, Suicide
- Trial name
- NCT04506164
- Testing
- eScreening, Screening As Usual
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chronic Kidney Disease
Peer-mentoring, Quality of Life and Caregiver Burden in Patients With Chronic Kidney Disease and Their Caregivers
Receiving supportive mentoring from well-adjusted individuals who share similar experiences has had a positive influence on adjustment with some chronic diseases.
- Trial name
- NCT02429115
- Testing
- Mentoring
- Where
- United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Generalized Anxiety Disorder, Seroquel XR
Generalized Anxiety and Seroquel
The 12 week clinical trial of Seroquel in Generalized Anxiety Disorder (GAD) patients will be combined with fMRI experiments.
- Trial name
- GAD (NCT01066143)
- Testing
- Seroquel XR
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Major Depressive Disorder (MDD), History of Childhood Sexual Abuse (CSA)
An Investigation of Early Life Stress and Depression
The purpose of this study is to investigate brain pathways within adult females (with a history of CSA that occurred between the ages of 5-14) with and without a current diagnosis of major depressive disorder (MDD).
- Trial name
- NCT01701258
- Testing
- Amisulpride
- Where
- 2 sites in United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Posttraumatic Stress Disorder, Sexual Assault
RCT for Innovating Stress-related eHealth
The Randomized Control Trial for Innovating Stress-related eHealth (RISE) Study tests the hypotheses that a highly promising digital therapeutic (RISE Guide) targeting anxiety sensitivity (AS) will be acceptable to women sexual…
- Conditions
- Posttraumatic Stress Disorder, Sexual Assault, Pain
- Trial name
- RISE (NCT05305235)
- Testing
- RISE Guide, Relaxation Control
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Post-Traumatic Stress Disorder
Effect of Propranolol on Preventing Posttraumatic Stress Disorder
This study will assess the effectiveness of taking propranolol soon after a traumatizing incident in reducing the incidence and severity of posttraumatic stress disorder in acutely traumatized individuals.
- Trial name
- NCT00158262
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Breast Cancer, Lung Cancer
Developing a Virtual Stress Management Intervention for Spousal/Partnered Caregivers of Solid Tumor Cancer Patients.
This randomized control trial will investigate the ability of an effective stress management psychoeducation program for employed caregivers to mitigate psychological distress and pathophysiology in spousal or partnered…
- Conditions
- Breast Cancer, Lung Cancer, Colon Cancer, Solid Tumor, Adult
- Trial name
- eCare (NCT04739696)
- Testing
- PEPRR, Pep-Pal
- Where
- United States
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Premature Birth, Pregnancy Preterm
Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study
This is a randomized comparative effectiveness study of two forms of enhanced prenatal care among 674 Medi-Cal eligible pregnant individuals in Fresno, California.
- Conditions
- Premature Birth, Pregnancy Preterm, Prenatal Stress, Depression, Anxiety
- Trial name
- EMBRACE (NCT04154423)
- Testing
- Glow! Group Prenatal Care, Individual Prenatal Care with CPSP
- Where
- 2 sites in United States
- Volunteers
- 678 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Anxiety State
Cranial Electrotherapy Stimulation and Acute Stress
The goal of this study is to quantify the effects of 20 sessions of Cranial Electrotherapy Stimulation (CES) on measures of acute stress responses in Soldiers.
- Trial name
- NCT06034496
- Testing
- Active CES
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Tufts University
Stress Disorders, Post-Traumatic, Depression
Psychological and Psychosocial Intervention With War-Affected Children
The investigators are interested in knowing whether a group-based, trauma-focused intervention (Trauma Focused Cognitive Behavioral Therapy) is superior to a more general, non trauma-focused, psychosocial intervention (Child…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Anxiety, Conduct
- Trial name
- NCT01509872
- Testing
- Trauma Focused Cognitive Behavioral Therapy, Child Friendly Space
- Where
- Republic of the Congo
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
PTSD
Supported Education Pilot
The goal of this project is to gather data necessary for a full scale trial of a supported education service for OIF/OEF veterans with PTSD.
- Trial name
- SEd (NCT01073657)
- Testing
- Supported Education, General Peer Support
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Bisexuality, Homosexuality
Skills to Empower Affirmative Men
Participants are Vietnamese national. Over the course of the study activities, approximately 184 self-identified Vietnamese national gay and bisexual men ages 18 and above living in HCMC, Viet Nam, as well as 10 key informants…
- Conditions
- Bisexuality, Homosexuality, HIV Infections
- Trial name
- VINA STEAM (NCT05732675)
- Testing
- "VINA STEAM" (Skills to Empower Affirmative Men)
- Where
- Vietnam
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Florida State University