Clinical trials: Stress Fractures
Stress Fracture of Tibia or Fibula
Fracture Recovery for Returning to Duty (Teriparatide STRONG)
The project goals are to improve combat readiness of U.S. Soldiers and sustain the availability of the military to deploy by, 1) decreasing the number of days not physically ready for duty after diagnosis of a diaphyseal tibial…
- Trial name
- NCT04589819
- Testing
- Teriparatide
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- University of South Carolina
Acute Stress Reaction, Cognitive Performance
Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress Reaction
The objective of this study is to test the effects of transcutaneous auricular neurostimulation (tAN) in treating or preventing performance degradation after an acute stressor.
- Trial name
- ASR (NCT06390267)
- Testing
- Sparrow Hawk (Active)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Spark Biomedical, Inc.
Plaster of Paris Injury to Skin
The Effect of Stress Ball in Reducing Anxiety and Fear in 6-12 Year Old Children
The aim of this study was to determine the effect of stress ball application on procedure-related anxiety and fear during plaster cast procedure in children aged 6-12 years.
- Trial name
- TSA-2023-12759 (NCT06486831)
- Testing
- Squeeze the stress ball.
- Volunteers
- 116 people
- Sponsor
- Ataturk University
Stress Reaction, Opioid Use
Effect of Fentanyl on Main Opioid Receptor (OPRM1) on Human Granulosa Cells.
Opioids is known that produce not only analgesia but also hyperalgesia through activation of central glutaminergic system-GABA. At the same time, recently it was found that the main opioid receptor (OPRM1) is present on human…
- Trial name
- NCT03248076
- Testing
- Fentanyl Citrate
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- George Papanicolaou Hospital
Premature Infant
Bonding Quality and Gene Expression in Fullterm Infants Compared to Late Preterm Infants and Preterm Infants With Early Skin to Skin or Visual Contact
Recent research has identified differences in the quality of mother-child interaction and gene expression of six key molecules involved in stress response and neurobehavioral development in preterm infants (born <32 weeks of…
- Trial name
- NCT03366285
- Testing
- Attachment story completion taks (ASCT)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University of Cologne
Anesthesia, Intravenous
Target Effect-site Concentration of Remifentanil in Transperineal Prostate Puncture
The research about the target effect-site concentration of remifentanil, inhibiting stress reaction of the perineal prostate puncture when Dexmedetomidine being continuous pumping
- Trial name
- NCT03428191
- Testing
- Remifentanyl+Dexmedetomidine
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese Medical Association
Acute Stress Reaction, Acute Stress Disorder
BXCL501 After Stress to Increase Recovery Success
This study will examine the safety and efficacy of BXCL501 to reduce ASR symptoms and behavioral changes among patients presenting to the Emergency Department (ED) after Motor Vehicle Collision (MVC).
- Conditions
- Acute Stress Reaction, Acute Stress Disorder, Post-traumatic Stress Disorder
- Trial name
- RISE (NCT06943404)
- Testing
- BXCL501 (dexmedetomidine HCl)
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Osteoarthritis, Knee
Clinical Trial to Evaluate the Efficacy and Safety of MegaCarti® in Knee Cartilage Defects
The MegaCarti® is the decellularized allogeneic cartilage and acts as a cover after bone marrow stimulation to prevent the loss of blood clots and induces cartilage regeneration by assisting in the location of stem cells derived…
- Trial name
- NCT05440370
- Testing
- MegaCarti®, Microfracture
- Where
- 4 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- L&C Bio
Stress Reaction, Behavior, Social
The Effects of Therapy Dogs on Child Biology and Behavior
The objective of this study is to apply a rigorous experimental design to test whether children's interactions with therapy dogs increase immediate prosocial behavior and reduce immediate biological response to stress.
- Trial name
- NCT03949569
- Testing
- Therapy Dog, Stuffed Toy Dog, 5 Minute Puppy Video
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Intensive Care Unit Patients, Pain Management
Effects of Voice Records on Patient Outcomes Surgical Intensive Care Unit
This randomized kontrolled study is aimed to contribute to the literature on recognising, evaluating and reducing stress in the intensive care unit, which is one of the main responsibilities of surgical nurses, and to increase…
- Conditions
- Intensive Care Unit Patients, Pain Management, Stress Response
- Trial name
- NCT07007754
- Testing
- Voice recording playback
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Aydin Adnan Menderes University
Preterm Infant
The Effects of Mother-infant Skin-to-skin Contact on Stress Response of Preterm Infants
This study will evaluate the effect of maternal-infant skin-to-skin contact (SSC) versus routine care on general stress in preterm infants in the neonatal intensive care unit (NICU).
- Trial name
- NCT05503238
- Testing
- Skin-to-skin contact, Routine care
- Where
- China
- Sponsor
- Children's Hospital of Fudan University
Insulin Resistance, Elderly Patient
The Effect of Taurine on Morbidity and Mortality in the Elderly Hip Fracture Patient
The purpose of this study is to reduce the postoperative morbidity and mortality in the elderly hip fracture patient, by giving them taurine peri-operatively.
- Conditions
- Insulin Resistance, Elderly Patient, Oxidative Stress
- Trial name
- TAUP (NCT00497978)
- Testing
- taurine
- Where
- Netherlands
- Volunteers
- 236 people
- Sponsor
- Medical Center Alkmaar
Rotator Cuff Tears, Microfractures
Microfracture Combined With Suture Bridge Technique Versus Greenhouse Technique in Treating of Rotator Cuff Injuries
Several biological augmentation procedures have recently been suggested to enhance tendon healing after Arthroscopic rotator cuff repair, such as marrow-stimulating technique with microfractures of the greater tuberosity.
- Trial name
- NCT04686968
- Testing
- Greenhouse Technique, Microfracture Combined With Suture Bridge Technique
- Volunteers
- 48 people
- Sponsor
- Beijing Jishuitan Hospital
Stress Fractures, Bone Geometry
Bone Geometry, Strength, and Biomechanical Changes in Runners With a History of Stress Fractures
Stress fractures are a common and debilitating injury for a variety of athletes however current evidence does not clearly allow easy prediction of athletes at risk for a first fracture.
- Conditions
- Stress Fractures, Bone Geometry, Bone Strength, Biomechanical Changes
- Trial name
- NCT00766077
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Utah
Rotator Cuff Tears, Micro Fracture
The Effect of Microfracture Procedure on Rotator Cuff Tendon Healing
Patients with complaints of shoulder pain or limitation of motion and had rotator cuff rupture diagnosed with magnetic resonance imaging will be analyzed and the patients with surgical indication will be included in a randomized…
- Trial name
- NCT04421417
- Testing
- Microfracture + Standard Arthroscopic Rotator Cuff Repair, Standard Arthroscopic Rotator Cuff Repair
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Göker Utku değer
Anhedonia, Stress Response
Stress Trajectories and Anhedonia in Adolescence Research Study
This project will examine how multiple biological measures from the brain and the body's stress response system contribute to anhedonia (the loss of pleasure) in adolescence.
- Conditions
- Anhedonia, Stress Response, Adolescent Development
- Trial name
- STAARS (NCT07040449)
- Testing
- Montreal Imaging Stress Task, Trier Social Stress Test for Children
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Prematurity, Stress Reaction
Pilot Study of Nursing Touch and Biobehavioral Stress
Randomized cross-over clinical trial to determine the effect of a nurse-administered comforting touch intervention on the biobehavioral stress responses of preterm infants hospitalized in the neonatal intensive care unit.
- Trial name
- P-NAT-BIO (NCT05030233)
- Testing
- Nurse-Administered Touch Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Ohio State University
Sleep Deprivation, Military Activity
Can Ammonium Inhalants Maintain Performance in Sleep Deprived Soldiers?
This study aims to examine the effectiveness of ammonia inhalants in countering the effects of total sleep deprivation on cognitive and physical performance tests relevant to military personnel.
- Conditions
- Sleep Deprivation, Military Activity, Sleep, Cognitive Change
- Trial name
- NCT05868798
- Testing
- Ammonia Inhalant
- Where
- Czechia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Jan Malecek
Stress Reaction, Coping Behavior
Influence of Medical Student Coping Behaviour Types on Health Related Behaviour and Stress Level on the Day of OSCE
Objective structured clinical examinations (OSCEs) have recently been incorporated in the French medical studies. They will soon be an important part of the national evaluation of the students, therefore being responsible for a…
- Conditions
- Stress Reaction, Coping Behavior, Exam Stress, Sleep Hygiene
- Trial name
- NCT05393206
- Where
- France
- Volunteers
- 490 people
- Sponsor
- Claude Bernard University
Suicide Mortality
The Developmental Origins of Suicide Mortality
Background: Suicide rates are rising. In 2013, it was the third leading cause of death in children ages 10-14. It was the second leading cause of death for ages 15-24. Many risk factors for suicide have been found.
- Trial name
- NCT03027440
- Where
- United States
- Volunteers
- 52,966 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)