Clinical trials: Stress Hyperglycemia, open to volunteers
Type 1 Diabetes, Type 2 Diabetes
Closed Loop Glucose Control in a Simulated ICU Setting
This is a proof of concept safety study of a rule-based closed loop glucose control system designed for use in the intensive care unit setting.
- Conditions
- Type 1 Diabetes, Type 2 Diabetes, Stress Induced Hyperglycemia
- Trial name
- NCT07646067
- Testing
- FUSION closed loop glucose control system
- Volunteers
- 6 people
- Sponsor
- Ideal Medical Technologies
Occupational Stress, Gender Related Stress
Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women
The goal of this hybrid Type 1 effectiveness-implementation trial is to test the extent to which a peer support and community resource navigation intervention improves psychological well-being, addresses non-biologic drivers of…
- Conditions
- Occupational Stress, Gender Related Stress, Social Isolation, Hypertension
- Trial name
- NCT07111026
- Testing
- Sisters for Heart Health, Basic intervention
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Emory University
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female
Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
The goal of this clinical trial is to determine the effectiveness of using a freeze-dried wild blueberry powder on cardiometabolic health, cognitive function, and gut microbiota composition in adult women with prediabetes.
- Conditions
- Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female, Adult, Endothelial Function (Reactive Hyperemia)
- Trial name
- NCT06735651
- Testing
- Wild Blueberry
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Georgia State University
Diabetes, Pre-diabetes
Effect of Oral L-arginine 3.32 g a Day on Oxidative Stress Influencing Beta Cell Function and Insulin Resistance.
The objective of this clinical trial is to explore whether L-arginine supplementation with 3.32g/day may enhance antioxidant defenses in overweight and obese patients with pre-diabetes and metabolic syndrome, possibly providing…
- Conditions
- Diabetes, Pre-diabetes, Metabolic Syndrome
- Trial name
- L-BIOARG (NCT06686069)
- Testing
- bioarginina zero
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Federico II University
Pancreatitis, Acute, Hyperglycaemia
Glucose Levels in Acute Pancreatitis and the Impact of Insulin Depletion and Bacterial Endotoxaemia
There are currently no early predictive biomarkers for severity of acute pancreatitis (AP) that would allow stratification of patients for potential early interventional therapies.
- Trial name
- GLIDE (NCT06972238)
- Volunteers
- 30 people
- Sponsor
- Manchester University NHS Foundation Trust
Type 1 Diabetes (T1D), Autoantibodies
Standardized Italian netwoRk Enrolling iNdividuals With Islet-Autoantibodies
This project characterizes the longitudinal progression of children and adults who have tested positive for one or more islet cell autoantibodies across the early stages of type 1 diabetes (T1D).
- Conditions
- Type 1 Diabetes (T1D), Autoantibodies, Hyperglycemia, Impaired Glucose Tolerance (Prediabetes)
- Trial name
- SIRENA (NCT07503366)
- Where
- 24 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Società Italiana di Endocrinologia e Diabetologia Pediatrica
Anesthesia, Continuous Glucose Monitoring
Metabolic Control in Anesthesia and Surgery
The goal of this observational study is to investigate how a standard dose of the drug dexamethasone affects blood sugar levels during and after non-cardiac surgery in adult patients.
- Conditions
- Anesthesia, Continuous Glucose Monitoring, Hyperglycemia Steroid-induced, Hyperglycemia Stress
- Trial name
- MACS (NCT07573930)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Zealand University Hospital
Prediabetes or Diabetes, Surgery Complications
The Prevalence of Hyperglycemia in Surgical Patients With Pre-diabetes
The goal of this study is to measure the prevalence and risks of hyperglycemia in surgical patients with prediabetes. The main questions it aims to answer are: What is the prevalence of hyperglycemia in surgical patients with…
- Conditions
- Prediabetes or Diabetes, Surgery Complications, Non-Cardiac/ Non-Thoracic Surgery, Stress Hyperglycemia
- Trial name
- NCT07662980
- Where
- Canada
- Volunteers
- 750 people
- Sponsor
- University of Calgary
Diabetic Macular Edema, Visual Impairment
Evaluation of Serum- and OCT Biomarkers in Patients With DME Treated With Anti-VEGF or Dexamethasone Implant
This study aims to investigate the association between serum biomarkers and clinical response to anti-VEGF or dexamethasone implant by assessing OCT-biomarkers in patients with diabetic macular edema, DME, and to compare these…
- Conditions
- Diabetic Macular Edema, Visual Impairment, Diabetes Mellitus, Hyperglycaemia (Diabetic)
- Trial name
- BiomarkerOCT (NCT06984822)
- Testing
- Anti-VEGF treatment, Dexamethasone implant, Treatment with intravitreal anti-VEGF OR Dexamethasone implant
- Where
- 2 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Vastra Gotaland Region
Hyperglycemia, Hyperglycemia Stress
Diabetes Clinical Decision Support
The purpose of this study is to determine the impact of an electronic medical record clinical decision support tool on rates of dysglycemia in the hospital, and its clinical and economical outcomes.
- Conditions
- Hyperglycemia, Hyperglycemia Stress, Diabetes, PreDiabetes
- Trial name
- NCT05447806
- Testing
- Active Electronic Medical Record Inpatient Diabetes Clinical Decision Support
- Where
- 2 sites in United States
- Volunteers
- 15,732 people
- Sponsor
- Milton S. Hershey Medical Center
Critical Illness, Hyperglycemia
Prognostic Value of Stress Hyperglycemia Ratio in Critically Ill Patients
Critically ill patients admitted to intensive care units (ICUs) frequently develop elevated blood sugar levels (hyperglycemia) as a result of acute illness-related stress, even if they do not have diabetes.
- Conditions
- Critical Illness, Hyperglycemia, Acute Kidney Injury, Multiple Organ Failure
- Trial name
- NCT07853911
- Volunteers
- 230 people
- Sponsor
- Assiut University
Critical Illness, Hyperglycemia
Stress Hyperglycemia Ratio and Glucose Variability in Critically Ill Patients
This prospective cohort study aims to evaluate the stress hyperglycemia ratio and glucose variability among critically ill patients admitted to the intensive care unit.
- Trial name
- NCT07892222
- Volunteers
- 75 people
- Sponsor
- Assiut University
Postoperative Delirium
Stress Hyperglycemia Ratio and Postoperative Delirium
Postoperative delirium is a common and serious complication associated with prolonged hospitalization, increased morbidity and mortality, and elevated healthcare costs.
- Trial name
- NCT07194096
- Testing
- no intervention
- Volunteers
- 15,000 people
- Sponsor
- Rao Sun
Posttraumatic Stress Disorder, Metabolic Syndrome
Assessing Trauma-related Links Between Affective and Metabolic Systems
KEY INFORMATION: The purpose of this study is to understand how insulin resistance (how your body processes sugar) and PTSD might be related. The goal is to improve the health of Veterans in three ways: 1.
- Conditions
- Posttraumatic Stress Disorder, Metabolic Syndrome, Insulin Resistance
- Trial name
- ATLAS (NCT07862712)
- Testing
- prazosin
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- VA Office of Research and Development