Clinical trials: Stress Reduction, open to volunteers
Acute Stress Reaction, Acute Stress Disorder
Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)
This study will examine the safety and efficacy of TNX-102 SL to reduce ASR symptoms and behavioral changes among patients presenting to the emergency department (ED) after motor vehicle collision (MVC).
- Conditions
- Acute Stress Reaction, Acute Stress Disorder, Neurocognitive Function, Post-traumatic Stress
- Trial name
- OASIS (NCT06636786)
- Testing
- Cyclobenzaprine HCl
- Where
- 9 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of North Carolina, Chapel Hill
Post Traumatic Stress Disorder
Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course
Investigators' overall objective is to compare methods of identifying individuals who may be experiencing challenges in Cognitive Processing Therapy (CPT) and compare methods of intervening to optimize treatment retention and…
- Trial name
- STEER (NCT06957067)
- Testing
- CPT Skills, Cognitive Processing Therapy, Present Centered Therapy
- Where
- 4 sites in United States
- Volunteers
- 280 people
- Sponsor
- United States Department of Defense
Post Traumatic Stress Disorder
Effect of Attentional Therapy on Post-traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is associated with an attentional bias towards negative stimuli, which is supposed to contribute to the development and the maintenance of the disorder.
- Trial name
- BATRAUMA (NCT05331534)
- Testing
- Eye-tracking assisted attention control training (ACTo), Attention control training (ACT)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Lille
Nurse, Burnout, Healthcare Workers
Adaptation and Evaluation of RESTORE
The purpose of this clinical trial is to test whether the RESTORE intervention works to reduce nurse burnout, by engaging nursing staff in system redesign to reduce job demands and increase job resources.
- Trial name
- NCT07104474
- Testing
- RESTORE
- Where
- United States
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Chronic Low-back Pain
Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment
This study will identify unique signatures that people have which can cause pain by evaluating biological, psychological, and social markers using artificial intelligence.
- Trial name
- IMPACT (NCT06106191)
- Testing
- Mindfulness meditation, Perspectives on pain, Discussion
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Boston Medical Center
PTSD - Post Traumatic Stress Disorder
Reported Experience Measurement on Reducing Patient Discomfort in Intensive Care
Hospitalisation in intensive care is always traumatic and can lead to a long rehabilitation process, slowed down by symptoms of anxiety and/or depression, and/or post-traumatic stress disorder (PTSD).
- Trial name
- PREMREA (NCT07525284)
- Testing
- PREMREA program
- Where
- France
- Volunteers
- 1,242 people
- Sponsor
- Almaviva Sante
Reduction of Empathy-Based Stress in Healthcare Staff
Compassion Project: Developing an Empathy-Based Stress Intervention
Compassion is recognising that someone is suffering and wanting to help them. Compassion fatigue is a reduction in capacity to feel compassion for others.
- Trial name
- NCT06343818
- Testing
- The Compassion Project: Intervention to Reduce Empathy-Based Stress in Staff
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bath
Body Image, Mindfulness Based Stress Reduction
MBSR Effects on Aging Anxiety and Body Image
This study was designed to determine the effect of a mindfulness-based stress reduction (MBSR) program on aging anxiety and body image among middle-aged women.
- Conditions
- Body Image, Mindfulness Based Stress Reduction, Middle Aged
- Trial name
- NCT07344896
- Testing
- bilinçli farkındalık temelli stres azaltma programı
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Menopause, Hot Flashes
Effect of a Mindfulness-Based Stress Reduction Program on Hot Flashes and Sleep Quality in Menopausal Women: A Randomized Controlled Trial
Menopause is a natural transition characterized by vasomotor symptoms such as hot flashes and sleep disturbances, which can significantly impair quality of life.
- Conditions
- Menopause, Hot Flashes, Sleep Wake Disorders
- Trial name
- MBSR-MENO (NCT07402096)
- Testing
- Mindfulness-Based Stress Reduction (MBSR)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Inonu University
Irritable Bowel Syndrome, Anxiety
Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is the most common cause of recurrent abdominal pain in children. IBS is a functional gastrointestinal disorder that is linked to motor and sensory physiology, as well as the central nervous system…
- Conditions
- Irritable Bowel Syndrome, Anxiety, Quality of Life
- Trial name
- NCT05719246
- Testing
- Yoga
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cooper Norcross Health
Sickle Cell Disease, Pain
Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease
Children with sickle cell disease may experience frequent painful episodes. This, together with the traumatic experiences during a hospitalization, can lead to the development of posttraumatic stress reactions.
- Conditions
- Sickle Cell Disease, Pain, Pain, Chronic Disease
- Trial name
- RELAX (NCT07001631)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR)
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Post-traumatic Stress Disorder (PTSD), Intrusive Memories of Traumatic Event(s)
Tetris Intervention Following Subliminal Reactivation for Intrusive Memories
Intrusive memories of traumatic events are a core feature of Post-Traumatic Stress Disorder (PTSD) and can cause substantial distress and functional impairment.
- Trial name
- NCT07495917
- Testing
- Subliminal Reactivation Followed by Visuospatial Interference, Computer-based Visuospatial Task (Tetris)
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Shaanxi Normal University
Stress, Trauma
Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness
The purpose of this study is to investigate justice-involved Black/African American female adolescents' (JI BAFAs; N=35) self-reported outcomes: stress, posttraumatic stress disorder (PTSD), recidivism, etc., as well as their…
- Conditions
- Stress, Trauma, PTSD, HPA
- Trial name
- NCT06311188
- Testing
- ITR Healing intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Postpartum Anxiety, Postpartum Period
Short-Term Mindfulness Intervention for Anxiety and Maternal Attachment in NICU Mothers
This randomized controlled study aims to evaluate the effects of a short-term mindfulness-based stress reduction (MBSR) program on anxiety levels and maternal attachment in mothers whose infants are admitted to the Neonatal…
- Conditions
- Postpartum Anxiety, Postpartum Period, Maternal Behavior, Psychological Stress
- Trial name
- NCT07520435
- Testing
- Mindfulness-Based Stress Reduction (MBSR) Program
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Depression, Posttraumatic Stress Disorder
Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa
Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in preventing HIV.
- Conditions
- Depression, Posttraumatic Stress Disorder, Pregnancy Related, Medication Adherence
- Trial name
- NCT05624931
- Testing
- Brief CBT-Based Intervention, Enhanced Treatment as Usual
- Where
- 2 sites in United States, South Africa
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Type 2 Diabetes Risk Reduction in Young Adults
Holistic Lifestyle mHealth Intervention for Risk Reduction of Type 2 Diabetes Mellitus in Young Adults
The goal of this clinical trial (randomized controlled trial) is to examine the effectiveness of a holistic lifestyle mHealth intervention in reducing the risk of type 2 diabetes mellitus.
- Trial name
- NCT07604012
- Testing
- Holistic mHealth Intervention
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Pregnancy in Adolescence, Fear
Effect of MBSR Training on Childbirth Fear, Bonding and Breastfeeding in Adolescent Pregnant Women
This randomized controlled study aims to evaluate the effect of Mindfulness-Based Stress Reduction (MBSR) training given to adolescent pregnant women and their partners on fear of childbirth, maternal and paternal bonding, and…
- Conditions
- Pregnancy in Adolescence, Fear, Mother-Child Relations, Mindfulness
- Trial name
- NCT07540923
- Testing
- Mindfulness-Based Stress Reduction (MBSR) Training
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Inonu University
LGBTQ, Racial Disparities
Lakota Family Acceptance Project Pilot RCT
Although research documents the concerning rates of mental and behavioral health problems (e.g., substance use/initiation) among Indigenous LGBTQ2S+ youth, there is very little known about how to prevent these deleterious issues…
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP (NCT07865858)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Post Traumatic Stress Disorder
Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
This study addresses PTSD symptoms in First Responders and Healthcare workers. Specifically, it tests whether a brief PTSD treatment (talk therapy) effectively treats PTSD when provided to First Responders and Healthcare workers…
- Trial name
- NCT05751473
- Testing
- Prolonged Exposure for Primary Care (PE-PC), EAP Treatment as Usual (TAU)
- Where
- 14 sites in United States
- Volunteers
- 410 people
- Sponsor
- University of Michigan
Alzheimer's Disease (AD), Older Adults (65 Years and Older)
Improv Music Therapy for Older Adults
Older adults and their care partners will participate in music therapy sessions for approximately 8 weeks. Before and after the 8 week study period, participants will fill out questionnaires about their mood, stress levels, and…
- Trial name
- NCT07419022
- Testing
- Clinical Improvisation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco