Clinical trials: Stress Testing
Physiological Conditions, Distress, Emotional
Hand in Hand: Feasibility of a Compassion-Focused App to Support Parents of Children With Mental Health Problems
Parents of children and adolescents with mental health problems may experience substantial caregiving burden and emotional distress, including persistent stress, self-criticism, shame, and parental burnout.
- Conditions
- Physiological Conditions, Distress, Emotional, Caregiving Stress, Burnout
- Trial name
- NCT07840404
- Testing
- App-based Compassion Program
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Post-Traumatic Stress Disorder
Effectiveness of a Web-based Intervention for Guardians of Children Whose One Parent Has Murdered the Other
This study will determine whether a specialized Web site geared for the guardians of children whose one parent has murdered the other can increase guardian capabilities, reduce guardian stress, and improve child behavior and…
- Trial name
- NCT00737035
- Testing
- Interactive Healthcare Communication Application, Control Web sites
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Heart Transplant Recipients
Intravenous Iron Supplement for Iron Deficiency in Cardiac Transplant Recipients
Iron deficiency is prevalent in heart transplant recipients, and may be associated with reduced functional capacity. The IronIC trial is designed to assess the effect of intravenous iron isomaltoside on exercise capacity, muscle…
- Trial name
- IronIC (NCT03662789)
- Testing
- Iron Isomaltoside 1000
- Where
- Norway
- Volunteers
- 102 people
- Sponsor
- Oslo University Hospital
Cardiorespiratory Fitness
Calibre vs. COSMED
This study evaluates agreement between the Calibre device and the COSMED Quark CPET system for measurement of cardiorespiratory fitness parameters during maximal exercise testing in adults aged 18-55 years.
- Trial name
- NCT07596108
- Testing
- COSMED Quark CPET metabolic cart, Calibre Biometrics
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Long-chain Fatty Acid Oxidation Disorders
Exercise Intolerance Study in Long Chain Fatty Acid Oxidation Disorders
In this study, the exercise tolerance in patients with long-chain fatty acid oxidation disorders (LcFAOD) will be compared to that of healthy volunteers who are carefully matched in terms of age, sex, BMI and physical activity…
- Trial name
- EXCITE LcFAOD (NCT05924555)
- Testing
- Intermittent cardiopulmonary exercise test, Incremental cardiopulmonary exercise test, Echography of upper leg
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pregnancy
Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)
The goal of this clinical trial is to evaluate the potential benefit to patients and providers from using the remote fetal-monitoring system NUVO along with its app to allow for pregnant patients requiring weekly non-stress…
- Trial name
- SHOW-ME (NCT06741735)
- Testing
- INVU fetal monitoring system
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Missouri-Columbia
Heart Failure
Exercise Oscillatory Breathing and Sildenafil in Heart Failure
Exercise oscillatory breathing (EOB) is a ventilatory abnormality that occurs in approximately 20% of heart failure (HF) patients and carries a very unfavourable prognosis.
- Trial name
- NCT01185925
- Testing
- Sildenafil
- Volunteers
- 32 people
- Sponsor
- University of Milan
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Spinal Stenosis
Validity and Reliability of the 2-minute Step Test in Patients With Lumbar Spinal Stenosis
The aim of this study was to investigate the validity and reliability of the 2 Minute Step Test (2MST) in patients with symptomatic degenerative lumbar spinal stenosis and to explore its correlation with objective assessment…
- Trial name
- NCT06060821
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Childhood Cancer
Cardiopulmonary Fitness and Its Clinical Determinants of a Population of Childhood Cancer Survivor
Medical progress have made it possible to considerably improve the survival of children with an oncological disease. Currently, the survival rate increased to above 90 % in the most developed countries .
- Trial name
- ONCO-SPORT (NCT04815447)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Montpellier
Type 1 Diabetes (T1D), Autoantibodies
Standardized Italian netwoRk Enrolling iNdividuals With Islet-Autoantibodies
This project characterizes the longitudinal progression of children and adults who have tested positive for one or more islet cell autoantibodies across the early stages of type 1 diabetes (T1D).
- Conditions
- Type 1 Diabetes (T1D), Autoantibodies, Hyperglycemia, Impaired Glucose Tolerance (Prediabetes)
- Trial name
- SIRENA (NCT07503366)
- Where
- 24 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Società Italiana di Endocrinologia e Diabetologia Pediatrica
Urodynamic Studies
Urodynamic Studies Prior to Surgery for Stress Urinary Incontinence
This retrospective descriptive study is to determine what proportion of Cincinnati Urogynecology Associates patients who underwent surgical management for stress urinary incontinence (SUI) would qualify for a basic office exam…
- Trial name
- NCT03107130
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- TriHealth Inc.
Prostate Cancer
Men With Metastatic Castrate-Resistant Prostate Cancer Treated With Either Sipuleucel-T (Provenge®), Abiraterone Acetate (Zytiga®) or Enzalutamide (Xtandi®) Undergoing Cardiopulmonary EXercise Testing
This is a pilot exercise physiology and quality of life study of subjects receiving standard of care therapy for their prostate cancer using FDA-approved drugs per their labeling (abiraterone, enzalutamide, or sipuleucel-T).
- Trial name
- PEAX (NCT02353715)
- Testing
- Enzalutamide, Abiraterone acetate, Sipuleucel-T
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Duke University
Coronary Artery Disease
Dynamic Cardiac SPECT Imaging
The investigators propose a 4 year prospective, observational study of 40 patients yearly, comparing conventional clinically indicated SPECT and PET perfusion with dynamic rest/stress MPI studies with coronary angiography, in…
- Trial name
- SPECT (NCT01934985)
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- University of California, San Francisco
Radionuclide Imaging (MIBG Scintigraphy), Exercise Test
The Effects of Continuous Positive Airway Pressure (CPAP) on Sympathetic Activity in Different Sites of Activation
Recent evidences suggest that obstructive sleep apnea (OSA) can contribute to cardiovascular disease even in the absence of hypertension.
- Conditions
- Radionuclide Imaging (MIBG Scintigraphy), Exercise Test, Blood Pressure Monitoring, Ambulatory, Sympathetic Nerve Activity
- Trial name
- NCT01336335
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Cystic Fibrosis, Fibrosis
The Alfred Step Test Exercise Protocol (A-STEP), for Adults With Cystic Fibrosis.
Exercise testing has become clinically important in the management and ongoing evaluation of patients with Cystic Fibrosis (CF) with higher rates of exercise tolerance and participation previously linked to lower mortality risk…
- Conditions
- Cystic Fibrosis, Fibrosis, Lung Diseases, Respiratory Diseases
- Trial name
- A-STEP (NCT02717650)
- Testing
- A-STEP, A-STEP (New Protocol), Comparator: CPET cycle ergometer (Gold Standard)
- Where
- Australia
- Volunteers
- 7 people
- Sponsor
- The Alfred
Heart Block AV
Micra AV Tracking During Exercise Testing
The purpose of this study is to determine the effectiveness of the Micra AV 2.0 device during exercise or elevated heart rates. Participation in research studies is voluntary.
- Trial name
- NCT05966168
- Testing
- Medtronic Micra AV Device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Cardiovascular Diseases, Cardiac Rehabilitation
Threshold-Based Versus Range-Based Exercise Intensity Prescription in Cardiac Rehabilitation
Cardiac rehabilitation is an important part of the treatment of patients with cardiovascular disease. Supervised aerobic exercise improves physical fitness, functional capacity, and quality of life.
- Trial name
- T-REXI-CR (NCT07908810)
- Testing
- Threshold-Based Aerobic Exercise Intensity Prescription, Range-Based Aerobic Exercise Intensity Prescription
- Where
- 9 sites in Belgium
- Volunteers
- 230 people
- Sponsor
- Hasselt University
Alcohol; Use, Problem, Posttraumatic Stress Disorder
Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault
Sexual assault can lead to devastating consequences including the development of chronic conditions including posttraumatic stress disorder (PTSD) and alcohol use disorders (AUD).
- Trial name
- NCT04124380
- Testing
- Imaginal Exposure, Alcohol Skills Training, Supportive Telehealth
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Washington
TOF
Quality of Life in Operated Adult Patients With Tetralogy of Fallot and Correlation With Myocardial Strain Analysis by CMR
Title: Functional Assessment and Arrhythmia Prediction in Adult Patients with Repaired Tetralogy of Fallot Using a Multimodality Approach Background: Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect.
- Trial name
- NCT07010510
- Testing
- CMR, stress ECG, Holter, BnP
- Volunteers
- 100 people
- Sponsor
- Assiut University