Clinical trials: Stroke, Acute, Ischemic
Stroke
ExStroke Pilot Trial: Physical Exercise After Acute Ischaemic Stroke
Summary This study will look at physical exercise after acute ischaemic stroke. It is called the ExStroke Pilot Trial. Physical activity is associated with a lower risk of first-time stroke.
- Trial name
- NCT00132483
- Testing
- Instruction in physical training program
- Where
- Denmark
- Volunteers
- 314 people
- Sponsor
- Bispebjerg Hospital
Ischemic Stroke
The Safety and Efficacy of Cerebrolysin in Patients With Acute Ischemic Stroke
The study investigated the clinical efficacy and safety of a 10-day course of therapy with daily intravenous administration of 30mL Cerebrolysin based on a comparison with Placebo in patients with acute ischemic stroke.
- Trial name
- CASTA (NCT00868283)
- Testing
- Cerebrolysin, 0.9% Saline Solution
- Where
- 49 sites in China, Hong Kong and 1 more
- Volunteers
- 1,071 people
- Sponsor
- Ever Neuro Pharma GmbH
Stroke, Ischemic Stroke
Efficacy of Diterpene Ginkgolides Meglumine Injection in Elderly Patients With Ischemic Stroke
A randomized positived-controlled study of Diterpene Ginkgolides Meglumine Injection (DGMI) vs Ginaton in patients with ischemic stroke (IS) was conducted between7/2013 and 4/2014.
- Conditions
- Stroke, Ischemic Stroke, Nervous System Diseases, Cerebral Infarction
- Trial name
- NCT05169450
- Testing
- Diterpene ginkgolides meglumine injection, Ginaton
- Where
- China
- Volunteers
- 998 people
- Sponsor
- Dongzhimen Hospital, Beijing
Stroke, Cerebral Venous System
Study of Cerebral Venous System in Acute Ischemic Stroke Patients Receiving Reperfusion Therapy
The VAST study is a single-center prospective observational study that enrolled individuals with acute ischemic stroke (AIS) within 24 hours onset.
- Conditions
- Stroke, Cerebral Venous System, Reperfusion Injury
- Trial name
- VAST (NCT03838289)
- Testing
- multimodal magnetic resonance imaging or computed tomography
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ischemic Stroke, Acute, Cerebrovascular Disorders
Post-thrombectomy Intra-arterial Tenecteplase for Acute manaGement of Non-retrievable Thrombus and No-reflow in Emergent Stroke
Multicentre, prospective, Multi-arm Multi-stage (MAMS) seamless phase 2b/3 interventional randomized placebo-controlled double-blinded parallel-assignment (2 arms with 1:1 randomization) efficacy and safety trial to test…
- Conditions
- Ischemic Stroke, Acute, Cerebrovascular Disorders, Brain Disorder, Central Nervous System Diseases
- Trial name
- NCT05892510
- Testing
- Intra-arterial tenecteplase injection at the completion of thrombectomy
- Where
- 12 sites in Australia, New Zealand
- Volunteers
- 462 people
- Sponsor
- University of Melbourne
Ischemic Stroke, Acute
Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke
Early antiplatelet therapy is promising for further improvement of functional prognosis on the basis of intravenous thrombolytic therapy.
- Trial name
- TAPIS (NCT06316570)
- Testing
- Early Dual Antiplatelet Therapy
- Where
- 60 sites in China
- Volunteers
- 1,382 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke, Acute
Brain-Oscillation-Synchronized Stimulation to Enhance Motor Recovery in Early Subacute Stroke
We will investigate the therapeutic efficacy of EEG-synchronized noninvasive repetitive transcranial magnetic stimulation (rTMS) in the early subacute phase after ischemic stroke to improve upper limb motor rehabilitation.
- Trial name
- Boss-Stroke (NCT05600374)
- Testing
- Bossdevice
- Where
- 4 sites in Germany
- Volunteers
- 144 people
- Sponsor
- University Hospital Tuebingen
Ischemic Stroke, Hyperglycemia
Assessment of Markers of Stress in Acute Ischemic Stroke With Hyperglycemia
Hyperglycemia is present in 50 percent of patients with acute ischemic stroke. Patients with hyperglycemia have higher in hospital, 30 and 90 day mortality and morbidity.
- Trial name
- ASIIST (NCT03318679)
- Testing
- No intervention is planned.
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Minnesota
Ischemic Strokes, Traditional Chinese Medicine (TCM)
Spatiotemporal Evolution of Traditional Chinese Medicine Mechanisms in Acute Ischemic Stroke Treated With Dengzhan Xixin and Dengzhan Shengmai
To integrate large-scale RCT data on clinical symptoms, TCM syndromes, prognosis, and multi-omics profiles, construct a spatiotemporal dynamic network for disease-syndrome evolution of acute ischemic stroke (AIS) in the acute and…
- Conditions
- Ischemic Strokes, Traditional Chinese Medicine (TCM), Prognosis
- Trial name
- STEM-DZ (NCT07591883)
- Testing
- Dengzhan Shengmai - Erigeron breviscapus sequential intervention, corresponding control group sequential intervention
- Volunteers
- 358 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Stroke, Acute Ischemic, PCSK9 Inhibitor
The Effect of Early Administration of PCSK9 Inhibitor to Acute Ischemic Stroke Patients Associated With Atherosclerosis on the Stroke Prognosis and Lipid Profile
The goal of this clinical trial is to test the effect of proprotein convertase subtilisin/kexin type 9 (PCSK9 inhibitors) in acute ischemic stroke patients associated with atherosclerosis by investigating 1.
- Trial name
- NCT06083961
- Testing
- Alirocumab
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Sun U. Kwon
Acute Ischemic Stroke (AIS)
Deep Learning Enabled Endovascular Stroke Therapy Screening in Community Hospitals
After onset of Acute Ischemic Stroke (AIS), every minute of delay to treatment reduces the likelihood of a good clinical outcome.
- Trial name
- NCT05838456
- Testing
- Viz.AI software
- Where
- United States
- Volunteers
- 443 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, Post-Stroke Cognitive Impairment
Immune-Inflammatory Biomarkers in Predicting Early Cognitive Impairment in Adults With Acute Basal Ganglionic Stroke
Post-stroke cognitive impairment (PSCI) is a common and disabling complication that affects memory, thinking, and daily functioning after a stroke.
- Conditions
- Stroke, Post-Stroke Cognitive Impairment, Ischemic Stroke, Intracerebral Hemorrhage
- Trial name
- NCT07837466
- Volunteers
- 100 people
- Sponsor
- Assiut University
Ischemic Stroke
Predictors and Prognostic Factors on the Acute Ischemic Stroke
Through 5 years continuous observation of acute ischemic stroke patients in Neurology Department of Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, clinical data about emergency treatment…
- Trial name
- NCT03122002
- Testing
- Drug Therapy, Routine Blood Test and Image Scan, Intravascular therapy
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Tongji Hospital
Stroke Inflammation
Fingolimod in Endovascular Treatment of Ischemic Stroke
Proof-of concept clinical trials have indicated that the sphingosine-1-phosphate receptor modulator fingolimod may be efficacious in attenuating brain inflammation and improving clinical outcomes in patients with acute ischemic…
- Trial name
- NCT04629872
- Testing
- Fingolimod
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Ning Wang, MD., PhD.
Acute Ischemic Stroke
Acute Ischemic Stroke Registry for Endovascular Treatment
The Acute Ischemic Stroke Registry for Endovascular Treatment (AIS-EVT) is an academic, prospective, multicenter, observational registry study.
- Trial name
- NCT05213754
- Testing
- Endovascular Treatment
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Capital Medical University
Ischemic Stroke
Total Posterior-circulation Infarct Volume in Basilar Artery Stroke
Preprocedural predictors of outcome in patients with acute basilar artery occlusion (ABAO) who underwent endovascular treatment (EVT) remain controversial.
- Trial name
- TPCIV-ABAO (NCT04650022)
- Testing
- Mechanical thrombectomy
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Montpellier
Acute Ischemic Stroke
EndovaSCular TreAtment to imProve outcomEs for Medium Vessel Occlusions (ESCAPE-MeVO Trial)
Stroke occurs when a blood clot causes a blockage in a blood vessel (artery) within the brain. This type of stroke is called an ischemic stroke and carries a high risk of disability or death. Stroke must be treated very fast.
- Trial name
- ESCAPE-MeVO (NCT05151172)
- Testing
- endovascular thrombectomy (EVT), Standarad medical care
- Where
- 53 sites in United States, Canada and 2 more
- Volunteers
- 530 people
- Sponsor
- Dr. Michael D Hill
Acute Ischemic Stroke
BXOS110 Injection in the Treatment of Acute Ischaemic Stroke
The purpose of this study was to evaluate the effectiveness of early administration of BXOS110 for injection in reducing overall disability in patients with acute ischaemic stroke.
- Trial name
- NCT06322394
- Testing
- high-dose BXOS110, low-dose BXOS110
- Where
- 24 sites in China
- Volunteers
- 300 people
- Sponsor
- Biocells (Beijing) Biotech Co.,Ltd
Stroke
Edaravone and Argatroban Stroke Therapy Study for Acute Ischemic Stroke
Edaravone, a free radical scavenger, is a novel neuroprotective agent, and argatroban is a selective thrombin inhibitor. Both the drugs were approved by the Japanese Government, and have frequently been used for the treatment of…
- Trial name
- EAST (NCT00153946)
- Testing
- Edaravone
- Where
- Japan
- Volunteers
- 814 people
- Sponsor
- Combination Therapy for Acute Ischemic Stroke Study Group
Acute Ischemic Stroke, Blood Pressure Variability
Blood Pressure Variability and Ischemic Stroke Outcome
The goal of this observational study is to evaluate the role of blood pressure (BPV) variability in patients suffering from acute ischemic stroke. The main questions it aims to answer are: 1.
- Trial name
- BP-VISO (NCT05756257)
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Yale University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.