Clinical trials: Stroke, Acute, Ischemic
Stroke, Ischemic, Acute Pain
Effects of Mirror Therapy Versus Fine Motor Activities on Hand Function in Chronic Stroke Patients.
to compare the effects of the Mirror therapy and fine motor activities on hand function in chronic stroke patients
- Conditions
- Stroke, Ischemic, Acute Pain, Weakness, Muscle
- Trial name
- NCT05506826
- Testing
- fine motor activities, conventional therapy and mirror therapy
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Ischemic Stroke
Epicardial Adipose Tissue Volume and Attenuation in Acute Ischemic Stroke
Excessive accumulation or abnormal distribution of adipose tissue is a recognized risk factor for ischemic stroke. However, the impact of overweight or obesity on clinical outcomes of ischemic stroke is uncertain.
- Trial name
- EATVAS (NCT05631808)
- Testing
- Epicardial adipose tissue volume and attenuation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Acute Ischemic Stroke
Safety and Efficacy of Heparin and Nadroparin in the Acute Phase of Ischemic Stroke
The goal of this study is to show the efficacy and safety of heparin and nadroparin in the acute phase of ischemic stroke. Therapeutic agents are administered at intervals of 4.5 to 2 hours after onset of clinical signs.
- Trial name
- Heparinas (NCT01862978)
- Testing
- Heparin, Nadroparin
- Where
- Slovakia
- Volunteers
- 150 people
- Sponsor
- University Hospital, Martin
Acute Stroke
Safety and Efficacy of Glibenclamide Combined With Rt-PA in Acute Cerebral Embolism
This study is designed to evaluate the safety and efficacy of oral glibenclamide in acute ischemic stroke patients who under intravenous rt-PA thrombolysis.
- Trial name
- SE-GRACE (NCT03284463)
- Testing
- Glibenclamide
- Where
- 8 sites in China
- Volunteers
- 306 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Acute Ischemic Stroke
Prospective Evaluation to Characterize the Real-World Performance of the EMBOVAC Aspiration Catheter
A post-market study evaluating the EMBOVAC Aspiration Catheter in acute ischemic stroke patients with confirmed intracranial large vessel occlusion.
- Trial name
- PERFECT (NCT04531904)
- Testing
- EMBOVAC Aspiration Catheter
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 102 people
- Sponsor
- Cerenovus, Part of DePuy Synthes Products, Inc.
Acute Ischemic Stroke
Impact of a Standardized Alarming System on Treatment Times and Workflow in Stroke Patients With Interhospital Transfer for Thrombectomy
The aim of this study is to evaluate the impact of a standardized alarming system on treatment times and workflow in stroke patients with interhospital transfer for mechanical thrombectomy (MT).
- Trial name
- NCT05963685
- Testing
- standardized MT alarming system
- Where
- Germany
- Volunteers
- 280 people
- Sponsor
- Munich Municipal Hospital
Stroke, Acute
Perfusion and Antihypertensive Therapy in Acute Ischemic Stroke
The purpose of this study is to provide a description of blood flow changes in the brain after blood pressure lowering drugs are given.
- Trial name
- PATIS (NCT02327793)
- Testing
- Nitroglycerin, Labetalol
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University of Alberta
Acute Ichemic Stroke, Brain Ischemia
Multimodal Investigation of Intracranial Clot Environment
Analysis of peri clot blood collected at the acute phase of stroke in order to understand physiopathological mechanisms involved in the cerebrovascular damage
- Trial name
- MISO (NCT04421326)
- Testing
- Analysis of the clot
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Trauma Injury, Acute Coronary Syndrome
Smart Glasses in Emergency Medicine From the Hangzhou Asian Games
The findings of our study will reveal that using smart glasses in the emergency department(ED) could facilitate patient admission. AR Smart Glasses offer the potential to enhance the effectiveness and speed of treatment within ED.
- Conditions
- Trauma Injury, Acute Coronary Syndrome, Stroke, Acute, Septic Shock
- Trial name
- SGINHZAG (NCT06623825)
- Testing
- teleconsultation by Augmented Reality smart glasses, teleconsultation by two-way radio connection.
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Sir Run Run Shaw Hospital
Acute Ischemic Stroke, Large Vessel Occlusion
Tenecteplase vs Medical Management in 4.5-24h LVO no Access to EVT
The goal of this clinical trial is to learn if tenectplase works to acute ischemic stroke (AIS) with onset 4.5-9 hours. It will also learn about the safety of tenectplase in AIS with onset 4.5-9 hours.
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Tenecteplase, Thrombolysis
- Trial name
- TNK LATE (NCT07168278)
- Testing
- TNK, Standard medical treatment
- Where
- China
- Volunteers
- 794 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Acute Ischemic Stroke
Real-World Evaluation of Recombinant Human Prourokinase for Acute Ischemic Stroke Within 4.5 Hours
Acute ischemic stroke is a major cause of disability and death. Intravenous thrombolytic therapy is an important treatment option when given within the appropriate time window.
- Trial name
- PRISM (NCT07787325)
- Testing
- Recombinant Human Prourokinase
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Acute Ischemic Stroke, Coronary Artery Disease
Cardiac CT Angiography in Patients With Acute Ischemic Stroke
Mortality rates after acute ischemic stroke remain high despite continuously improving treatment. In this context, it is important to note that a relevant portion of acute ischemic stroke patients die from adverse cardiovascular…
- Trial name
- ACUTE (NCT06176872)
- Testing
- Cardiac Computed Tomography Angiography
- Volunteers
- 165 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Ischemic Stroke
Impact of Remote Ischemic Postconditioning on Autonomic Function in Stroke Patients
The purpose of this study is to determine whether remote ischemic postconditioning (RIPostC) initiates autonomic nervous system response and affects the prognosis in patients with acute ischemic stroke.
- Trial name
- IRAS (NCT02777099)
- Testing
- remote ischemic postconditioning
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Stroke
Safety Study of External Counterpulsation as a Treatment for Acute Ischemic Stroke
The purpose of this study is to determine if external counterpulsation (ECP) is feasible to perform, tolerable, and safe as a treatment for patients with acute ischemic stroke (i.e., a blockage of one of the arteries supplying a…
- Trial name
- CUFFS (NCT00983749)
- Testing
- Full-pressure ECP
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of California, San Diego
Stroke, Ischemic, Medium Vessel Occlusions
Advancing Reperfusion Therapy for Ischemic Stroke (ARTS): Tenecteplase in Medium Vessel Occlusion (MeVO) for Acute Ischemic Stroke
Results from recent several trials provided data showing limits to the effectiveness of thrombectomy for ischemic stroke due to medium vessel occlusions.The benefit-risk profile of thrombolysis for these patients has never been…
- Trial name
- ARTS-MeVO (NCT07047014)
- Testing
- Tenecteplase (0.25mg/kg), Standard medical treatment
- Where
- 7 sites in China
- Volunteers
- 596 people
- Sponsor
- Beijing Tiantan Hospital
Acute Ischemic Stroke
Intravenous Thrombolysis With rhTNK-tPA for Acute Non-large Vessel Occlusion in Extended Time Window
This study is designed to evaluate the efficacy of IV rhTNK-tPA between 4.5 to 24 hours from symptom onset in patients presenting with a non-large vessel occlusion ischemic stroke.
- Trial name
- OPTION (NCT05752916)
- Testing
- rhTNK-tPA, Antiplatelet Agents
- Where
- China
- Volunteers
- 570 people
- Sponsor
- Xuanwu Hospital, Beijing
Ischemic Stroke, Minor Stroke
Butylphthalide for Long-term Efficacy in Minor Stroke Study
This study is a multicenter, randomized, double-blind, placebo-controlled trial designed to evaluate the long-term efficacy and safety of butylphthalide in patients with minor acute ischemic stroke (BLESS Trial).
- Trial name
- BLESS (NCT07230587)
- Testing
- Butylphthalide
- Volunteers
- 1,200 people
- Sponsor
- Peking Union Medical College Hospital
Ischemic
Exploratory Study on the Effects of Early Rosuvastatin Treatment in Patients With Acute Ischemic Stroke
This is an exploratory, randomized, open-label, 2-arm, parallel-group study exploring the efficacy of rosuvastatin (20mg/day) in patients with acute ischemic stroke.
- Trial name
- AIS (NCT02643784)
- Testing
- Rosuvastatin, Control
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Ischemic Stroke, Cardioembolic Stroke
Diagnostic Yield of Cardiac CT to Detect Cardiac Thrombi in Acute Ischemic Stroke: an Individual Patient Data Meta-Analysis
The aim of the AIS of HEARTS registry is to establish a database to collect, maintain and provide accessible individual patient data from international cohorts and to provide pooled analyses about the yield and value of cardiac…
- Conditions
- Ischemic Stroke, Cardioembolic Stroke, Thrombus, Cardiac CT
- Trial name
- AIS of HEARTS (NCT07165093)
- Where
- Netherlands
- Volunteers
- 3,940 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Acute Ischemic Stroke
Association of Prophylactic Use of Stress Ulcer Drugs and Clinical Outcomes in Patients With Acute Anterior Circulation Thrombectomy
Ischemic stroke accounts for a relatively high proportion of strokes. In recent years, intravenous thrombolysis and endovascular therapy have significantly improved the revascularization rate in patients with large vessel…
- Trial name
- NCT05845372
- Where
- 19 sites in China
- Volunteers
- 2,592 people
- Sponsor
- Nanfang Hospital, Southern Medical University
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