Clinical trials: Stroke, Acute, Ischemic
Stroke Acute, Acute Ischemic Stroke AIS
One-Stop manaGemEnT For A Swift Initiation of Endovascular Therapy
Stroke, especially acute ischemic stroke (AIS) caused by a blocked blood vessel in the brain, is a leading cause of death and long-term disability.
- Conditions
- Stroke Acute, Acute Ischemic Stroke AIS, Hemorrhagic Stroke, Intracerebral
- Trial name
- GET-FAST (NCT07052045)
- Testing
- One Stop Management, Usual care management
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 390 people
- Sponsor
- Prof. Dr. Jan Liman
Acute Ischemic Stroke
Research Into the Effect of a Clot-dissolving Agent and Its Inhibitor
Single-chain urokinase-type plasminogen activator (pro-urokinase) is a highly effective thrombolytic drug. At pharmacologic concentrations however, pro-urokinase is converted to urokinase - a non specific thrombolytic, limiting…
- Trial name
- NCT01694381
- Testing
- M5, C1-inhibitor
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- TSI, LLC
Ischemic Stroke, Stroke
Effective Translation of Endovascular Thrombectomy Trials Into Real-world Practice in the Asia-Pacific
As a major breakthrough of acute stroke treatment over the past decade, endovascular thrombectomy (EVT) drastically improved neurological recovery and survival in patients with large vessel occlusion (LVO) ischemic strokes in…
- Conditions
- Ischemic Stroke, Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- NCT05578300
- Testing
- Thrombus analyses, Imaging assessment
- Where
- 3 sites in China, Hong Kong
- Volunteers
- 350 people
- Sponsor
- Chinese University of Hong Kong
Acute Ischemic Stroke
Registration of Acute Ischemic Stroke With Large and Medium-sized Vascular Occlusion in Southwest China(LMVOS)
This study is designed to observe the treatment options in real-world clinical practice as well as the safety and efficacy of different treatment strategies.
- Trial name
- LMVOS (NCT06125236)
- Testing
- Visit at D90
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Zhengzhou Yuan
Traumatic Brain Injury, Intracerebral Hemorrhage
Clinical Decision Support System for Early Mobilization in the Neuro-ICU
This study aims to evaluate the feasibility, safety, and user acceptability of a tablet- and smartphone-based Clinical Decision Support System (CDSS) designed to guide early mobilization for patients with severe neurological…
- Conditions
- Traumatic Brain Injury, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Spontaneous, Acute Ischemic Stroke
- Trial name
- CDSS-EM-ICU (NCT07685145)
- Testing
- Clinical Decision Support System (CDSS) for Early Mobilization
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
Acute Cerebral Stroke Within 12 Hours for the First Time
Dl-3-n-butylphthalide and Cerebrolysin Treatment in Acute Ischemic Stroke
The investigators conducted a randomized, double-blind, trial enrolled 60 patients within 12 hours of acute ischemic stroke (AIS) in China.
- Trial name
- NCT02149875
- Testing
- Dl-3-n-butylphthalide, Cerebrolysin
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shanghai 6th People's Hospital
Stroke, Acute Coronary Syndrome
Factors Associated With Perioperative Outcomes in Non-emergency Surgery
This epidemiological study investigates the association of recent stroke, acute coronary syndrome or pneumonia and adverse perioperative outcomes following elective non-cardiac and cardiac surgery using routinely collected UK…
- Conditions
- Stroke, Acute Coronary Syndrome, Pneumonia
- Trial name
- NCT02455492
- Testing
- stroke or myocardial infarction or pneumonia
- Volunteers
- 266,436 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Acute Ischemic Stroke
Heparin for RAO Post-Transradial Angiography in AIS
Cerebral angiography is a critical diagnostic tool in neurology, serving as the "gold standard" for evaluating cerebrovascular stenosis, hemodynamics, aneurysms, and arteriovenous malformations.
- Trial name
- NCT07162064
- Testing
- Heparin - Therapeutic dosage, Saline (0.9% NaCl)
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Xiang Luo
Cerebral Infarction
The Effect of Erigeron Injection on Acute Cerebral Infarction Serum VEGF, MMP-9 and EPC Levels
To study the effects of Erigeron Injection on human serum VEGF, MMP-9 and EPC levels after acute cerebral infarction,test is made by random double-blind controlled.patients with acute cerebral infarction were divided randomly…
- Trial name
- NCT01926834
- Testing
- Erigeron Injection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Acute Ischemic Stroke
Head Pulse for Ischemic Stroke Detection
Accurate diagnosis of stroke due to large vessel occlusion (LVO) is an essential step in providing acute stroke care to a community.
- Trial name
- EPISODE (NCT03824496)
- Testing
- Cranial Accelerometry Measurement
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Francisco
Acute Ischemic Stroke
Acute Ischemic Stroke Registry for Endovascular Treatment
The Acute Ischemic Stroke Registry for Endovascular Treatment (AIS-EVT) is an academic, prospective, multicenter, observational registry study.
- Trial name
- NCT05213754
- Testing
- Endovascular Treatment
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Capital Medical University
Ischemic Stroke
SITS (Safe Implementation of Treatments in Stroke) Open Artery by Thrombectomy in Acute Occlusive Stroke Study
Ischemic stroke, i.e. irreversible damage of a part of the patient's brain, is caused by the formation of blood clot in the major vessel which gives blood supply to a certain part of the brain.
- Trial name
- SITS Open (NCT02326428)
- Testing
- Stent retriever endovascular device for thrombectomy, Intravenous thrombolysis by alteplase (Actilyse) (optional)
- Where
- Sweden
- Volunteers
- 341 people
- Sponsor
- Karolinska Institutet
Acute Ischemic Stroke, Hemorrhagic Stroke
Mapping the Natural History of Parenychymal and Cerebral Perfusion Changes in Acute Ischemic and Hemorrhagic Strokes
Study using ultrasound of the brain as a diagnostic tool to differentiate between ischemic stroke and hemorrhagic stroke. Correlation of brain perfusion and size of stroke in relation to systemic hemodynamic targets will be…
- Trial name
- NCT05865795
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Wake Forest University Health Sciences
Ischemic Stroke, Acute
Stroke Process in FEmoral Versus Radial Access
In patients with suspected acute stroke due to large vessel occlusion with indication for endovascular treatment, radial access is just as safe, fast, and effective as femoral access, and it improves the entire stroke treatment…
- Trial name
- SFERA (NCT05225636)
- Testing
- thrombectomy
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Stroke
Beta Blockers In Acute Ischemic Stroke
The objective of this trial is to assess the safety and efficacy of neuro- and cardioprotective effects of propranolol in acute ischemic stroke.
- Trial name
- BIAS (NCT01061190)
- Testing
- Propranolol
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Wilhelm Haverkamp
Acute Stroke
Evaluate the Safety and Explore Efficacy of Umbilical Cord Mesenchymal Stem Cells in Acute Ischemic Stroke
This study is a first-in-human assessment of safety of using umbilical cord mesenchymal stem cells (UCMSCs) in patients with Acute Ischemic Stroke via a combination of intra arterial (IA) and intravenous (IV) stem cell…
- Trial name
- NCT04434768
- Testing
- UMSC01
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Ever Supreme Bio Technology Co., Ltd.
Acute Stroke, Cerebral Ischemia
A Study to Evaluate the Q Revascularization System for Neurointervention in Acute Ischemic Stroke
Assess the safety and efficacy of the Q Revascularization System to remove thrombi and emboli from the neurovasculature in patients experiencing an acute ischemic stroke
- Trial name
- EvaQ (NCT04437862)
- Testing
- Q Revascularization System
- Where
- 8 sites in United States, France
- Volunteers
- 121 people
- Sponsor
- MIVI Neuroscience, Inc.
Cerebral Infarction
Contrast Enhanced Ultrasound of Carotid Plaque in Acute Ischemic Stroke
This is a biomedical, single-center, and prospective study of a consecutive patients cohort in acute ischemic stroke with carotid plaque.
- Trial name
- CUSCAS (NCT03115242)
- Testing
- Contrast injection Sonovue®
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Versailles Hospital
Ischemic Stroke
Indicators of Quality Care and Services for Adults With Acute Ischemic Stroke in Different Types of Hospitals in Quebec : Research Protocol
The goal of this study is to describe the performance of care and services offered to people hospitalized with ischemic stroke. More specifically, this study aims to answer the following questions: Is stroke care and service…
- Trial name
- IndiQ-AVC (NCT06638242)
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Amelie Belanger
Ischemic Stroke
Change in Serum Biomarkers After Endovascular Treatment for Acute Anterior Circulation Large Vessel Occlusion
Acute ischaemic stroke (AIS) results in high rates of neurological morbidity and mortality, especially in patients with large vessel occlusion (LVO).
- Trial name
- NCT06383182
- Testing
- endovascular treatment
- Where
- China
- Volunteers
- 800 people
- Sponsor
- General Hospital of Shenyang Military Region
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