Clinical trials: Stroke, Acute, Ischemic
Acute Ischemic Stroke
XuanwuH Acute Ischemic Stroke Registry
Acute ischemic stroke registry--Xuanwu Hospital(XSR) is an academic, independent, prospective, single center, observational registry study.
- Trial name
- NCT05208203
- Testing
- telephone call d90
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Cerebral Infarction
Stroke Telemedicine for Arizona Rural Residents Trial
The STARR network registry consists of a 4 spoke 1 hub system. Which will consist of prospective collection, recording, and regular analysis of telestroke patient consultation and care data for the purpose of quality measure…
- Conditions
- Stroke, Cerebral Infarction, Vascular Diseases, Brain Ischemia
- Trial name
- STARR (NCT00829361)
- Testing
- Telemedicine
- Where
- United States
- Volunteers
- 447 people
- Sponsor
- Mayo Clinic
Ischemic Stroke, Hyperglycemia
Assessment of Markers of Stress in Acute Ischemic Stroke With Hyperglycemia
Hyperglycemia is present in 50 percent of patients with acute ischemic stroke. Patients with hyperglycemia have higher in hospital, 30 and 90 day mortality and morbidity.
- Trial name
- ASIIST (NCT03318679)
- Testing
- No intervention is planned.
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Minnesota
Acute Ischemic Stroke
The Efficacy and Safety of HRS-4029 in Acute Ischemic Stroke Patients
This trial will evaluate the efficacy and safety of HRS-4029 compared with placebo in participants with acute ischemic stroke (AIS).
- Trial name
- NCT07739160
- Testing
- HRS-4029
- Where
- China
- Volunteers
- 340 people
- Sponsor
- Beijing Suncadia Pharmaceuticals Co., Ltd
Ischemic Stroke
AdminiStration of Statin On Acute Ischemic stRoke patienT Trial
Investigators will study whether immediate statin treatment after the onset of stroke is beneficial on the neurological protection
- Trial name
- ASSORT (NCT02549846)
- Testing
- Statin
- Where
- Japan
- Volunteers
- 270 people
- Sponsor
- Hyogo Medical University
Acute Ischemic Stroke
Efficacy and Safety of Human Urinary Kallidinogenase for Acute Ischemic Stroke Patients Receiving Reperfusion Treatment
This study aims to explore the efficacy and safety of Human Urinary Kallidinogenase for acute ischemic stroke patients receiving intravenous thrombolysis and/or endovascular treatment.
- Trial name
- UNITE (NCT06848894)
- Testing
- Human urinary kallidinogenase (HUK)
- Where
- China
- Volunteers
- 1,204 people
- Sponsor
- Beijing Tiantan Hospital
Cognitive Impairment
Induced Pluripotent Stem Cells-derived Small Extracellular Vesicles May Promote Neurological Function and Improve Cognitive Impairment in Acute Ischemic Stroke Patients
This study primarily evaluates whether iEV nasal administration can improve neurological impairment and cognitive dysfunction in patients with acute cerebral infarction and cognitive impairment, and preliminarily explores its…
- Trial name
- NCT07145294
- Testing
- iEV, Basic treatments
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Hongmei Wang
Stroke
Neuroprotection With Statin Therapy for Acute Recovery Trial (Neu-START)
The purpose of this dose escalation study is to evaluate the use of lovastatin for the treatment of acute ischemic stroke.
- Trial name
- Neu-START (NCT00243880)
- Testing
- lovastatin
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Columbia University
Ischemic Stroke
The Norwegian Sonothrombolysis in Acute Stroke Study Part 2
BACKGROUND: Thrombolytic drugs may dissolve blood vessel clots in acute ischemic stroke. The overall benefit of intravenous thrombolysis is substantial, but up to 2/3 of patients with large clots may not achieve re-opening of the…
- Trial name
- NOR-SASS 2 (NCT01949961)
- Testing
- Ultrasound
- Where
- Norway
- Volunteers
- 59 people
- Sponsor
- Haukeland University Hospital
Ischemic Stroke
Predictors and Prognostic Factors on the Acute Ischemic Stroke
Through 5 years continuous observation of acute ischemic stroke patients in Neurology Department of Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, clinical data about emergency treatment…
- Trial name
- NCT03122002
- Testing
- Drug Therapy, Routine Blood Test and Image Scan, Intravascular therapy
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Tongji Hospital
Ischemic Stroke, Acute Stroke
Aerobic Exercise Training in Acute Ischaemic Stroke
Stroke is a leading cause of adult disability in the UK. There are few treatment options that improve long-term disability outcomes after stroke.
- Conditions
- Ischemic Stroke, Acute Stroke, Cerebrovascular Accident
- Trial name
- ATAS (NCT04742686)
- Testing
- Aerobic exercise training
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sheffield Hallam University
Acute Ischemic Stroke, Ischemic Stroke
Zeit Alert for Stroke at Home (ZASH) Protocol
This is a single-arm, observational, feasibility study to evaluate if the Halo Alert System can be used in the future to detect stroke events in individuals at risk for stroke wearing the Halo Alert System overnight.
- Conditions
- Acute Ischemic Stroke, Ischemic Stroke, Stroke
- Trial name
- ZASH (NCT05669456)
- Testing
- Halo Alert System
- Volunteers
- 300 people
- Sponsor
- Zeit Medical, Inc.
Atherosclerosis, Inflammation
Atherosclerosis and Acute Ischemic Stroke Study
A significant proportion of strokes are thromboembolic in nature, arising from atherosclerotic plaque at the carotid bifurcation. It is now wellknown that inflammation plays a key role in atherogenesis and plaque destabilization.
- Conditions
- Atherosclerosis, Inflammation, Ischemic Stroke
- Trial name
- NCT03685006
- Where
- Norway
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Acute Ischemic Stroke
Evaluate Endovascular Treatment of Large Ischemic Stroke With Substantial Penumbra.
Large cerebral infarctions are frequent and associated with a poor outcome. Previous cohort studies results suggest that patients with an acute ischemic stroke with large core and substantial penumbra on perfusion imaging benefit…
- Trial name
- FrameLP (NCT05539404)
- Testing
- Endovascular treatment in addition of best medical treatment.
- Where
- 9 sites in France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Toulouse
Acute Ischemic Stroke
Efficacy and Safety of the KPCXM18 Injection in Patients With Acute Ischemic Stroke
This study is a multicenter, randomized, double-blind, parallel, placebo-controlled trial design to evaluate the efficacy and safety of the KPCXM18 injection at different doses for the treatment of acute ischemic stroke.
- Trial name
- KPCXM18 (NCT07279493)
- Testing
- The KPCXM18 injection
- Where
- 23 sites in China
- Volunteers
- 300 people
- Sponsor
- Kunming Pharmaceuticals, Inc.
Ischemic Stroke, Acute
Lumbrokinase vs Placebo in Moderate-to-Severe Ischemic Stroke
LUMEN is a multicenter, randomized, double-blind, placebo-controlled superiority trial designed to evaluate whether oral lumbrokinase enteric-coated capsules combined with aspirin improve functional outcomes compared with aspirin…
- Trial name
- NCT07763405
- Testing
- Lumbrokinase
- Volunteers
- 1,196 people
- Sponsor
- Xinqiao Hospital of Chongqing
Post-stroke Cognitive Impairment
Edaravone Dexborneol Sublingual Tablet for the PSCI in Acute Ischemic Stroke Patients
This is a multicenter, randomized, double-blind, placebo-controlled, exploratory Phase II clinical trial. The goal of this clinical trial is to assess the safety and efficacy of edaravone dexborneol sublingual tablets for…
- Trial name
- NCT06315231
- Testing
- Edaravone dexborneol sublingual tablet
- Where
- 21 sites in China
- Volunteers
- 226 people
- Sponsor
- Simcere Pharmaceutical Co., Ltd
Acute Ischemic Stroke
Effect of Serial Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation in Patients With Intravenous Thrombolysis (SRICDCA-IVT)
The purpose of this study is to determine the effect of serial remote ischemic conditioning on dynamic cerebral autoregulation in patients with intravenous thrombolysis with alteplase.
- Trial name
- SRICDCA-IVT (NCT05550103)
- Testing
- Remote ischemic conditioning, Standard medical treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yi Yang
Stroke, Ischemic
Sensory Versus Motor Level Neuromuscular Electrical Stimulation
Dysphagia is a serious cause of morbidity and mortality in stroke survivors. Electrical stimulation is often included as part of the treatment plan for dysphagia, and can be applied at a sensory or motor level intensity.
- Trial name
- NMES (NCT05102877)
- Testing
- Neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Ischemic Stroke
Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism (RESCUE)-Japan RCT
The aim of this study is to clarify the efficacy of the endovascular treatment for acute ischemic stroke patients with large vessel occlusion and are not respond to intravenous recombinant tissue plasminogen activator (rt-PA)…
- Trial name
- NCT02419781
- Testing
- Rescue endovascular therapy, No endovascular therapy
- Where
- Japan
- Volunteers
- 19 people
- Sponsor
- Shinichi Yoshimura
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