Clinical trials: Stroke, Acute, Ischemic
Acute Ischemic Stroke
A Qualitative Study of Delays in Hospital Admission in Patient With Acute Stroke
To identify the circumstance during decision making processes to seek medical help in patients with symptoms of acute ischemic stroke.
- Trial name
- NCT00694395
- Volunteers
- 20 people
- Sponsor
- Far Eastern Memorial Hospital
Stroke, Acute
Statins Role in Acute Ischemic Stroke
Strokes is amajor cause of death and disabilities in different countried
- Trial name
- observation (NCT06371495)
- Testing
- rosuvastatin
- Volunteers
- 105 people
- Sponsor
- Assiut University
Acute Stroke
Cytoflavin in Combination With Reperfusion in Stroke Patients
Evaluation of the efficacy and safety of Cytoflavin®, solution for intravenous administration, (OOO NTFF POLYSAN, Russia) for 10 days, patients with cerebral infarction who receive reperfusion therapy, with the start of treatment…
- Trial name
- NCT05297851
- Testing
- Cytoflavin (succinic acid + inosine + nicotinamide + riboflavin), Control
- Where
- 7 sites in Russia
- Volunteers
- 200 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
Ischemic Stroke
Connectomic Alterations Following Acute Ischemic Stroke in the MCA Territory
This study seeks to use safe, powerful, non-invasive computing tools, including machine learning and advanced neuroimaging analysis, to better understand how stroke affects the brain's network of connections.
- Trial name
- NCT07584681
- Testing
- MRI with connectomic sequencing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Northwell Health
Acute Ischemic Stroke
Safety Study of PP-007 in Subjects With Acute Ischemic Stroke
The HEMERA-1 Extension (Part III) is a prospective, open-label, multicenter study to evaluate safety of two doses of PP-007 in Acute Ischemic Stroke (AIS) subjects receiving Intravenous Thrombolysis (IVT) or mechanical…
- Trial name
- HEMERA-1 (NCT04677777)
- Testing
- PP-007 (Two doses administered 24±6 hours apart) + SOC (IVT or MT or IVT+MT)
- Where
- 8 sites in United States
- Volunteers
- 24 people
- Sponsor
- Prolong Pharmaceuticals
Stroke
CT Based Definition of a Tissue Window for Acute Stroke Thrombolysis
Aim of this study is to define a CT-based "tissue window" for stroke thrombolysis. Our primary hypothesis is that 1. patients with a "tissue window" (favourable non-contrast CT (NCCT) scan and an intracranial occlusion on CT…
- Trial name
- CT-DEFINE (NCT00463281)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technische Universität Dresden
Stroke, Ischemic, Stroke Hemorrhagic
Study on the Performance of a Machine Learning Algorithm Recognizing and Triaging Large Vessel Occlusions Using Non-contrast CT Scans
The goal of this prospective observational study is to assess the effectiveness and performance of Methinks AI stroke imaging software platform in acute Code Stroke patients, and as a comparator to study sites utilizing existing…
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Acute, Brain Ischemia
- Trial name
- SMART-LVO (NCT06216457)
- Testing
- AI software for Stroke
- Volunteers
- 5,000 people
- Sponsor
- Methinks Software SL
Acute Stroke, Ischemic Stroke
Analysing the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke
The main purpose of this trial is to analyse the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke by Metabonomics, proteomics and clinical parameters.
- Trial name
- NCT04813445
- Testing
- Xingnaojing injection
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dongzhimen Hospital, Beijing
Ischemic Stroke
Intra-arterial Bone-marrow Mononuclear Cells Infusion for Acute Ischemic Stroke
This trial aims to test that intra-arterial injection of autologous bone marrow mononuclear cells in acute ischemic stroke patients is safe and improves neurological outcomes.
- Trial name
- NCT02178657
- Testing
- Autologous bone marrow mononuclear cell intra-arterial injection
- Where
- 4 sites in Spain
- Volunteers
- 76 people
- Sponsor
- Andalusian Initiative for Advanced Therapies
Acute Stroke
Evaluation Study of Early Administration of Evolocumab After Thrombolysis in Patients With Atherosclerotic Acute Ischemic Stroke
This study is a Phase IIa clinical trial initiated by the researchers, which is prospective, single-center, randomized, open-label, with blinded endpoint evaluation (PROBE design).
- Trial name
- EPOCH-LYSIS (NCT07301372)
- Testing
- Ivolumab 420mg (three vials)
- Where
- China
- Volunteers
- 132 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Ischemic Stroke
Ticagrelor Versus Cilostazol in Minor Ischemic Stroke or TIA
Along with the current clinical trial, the efficacy and safety of ticagrelor and aspirin administered within the first 24 hours of first-ever ischemic stroke compared to cilostazol and aspirin were assessed through NIHSS, mRS…
- Trial name
- NCT06196047
- Testing
- Ticagrelor 90 MG, Cilostazol 100 MG
- Where
- Egypt
- Volunteers
- 900 people
- Sponsor
- Kafrelsheikh University
Acute Ischemic Stroke
Eptifibatide for Extended Window Ischemic Stroke After Thrombolysis
This is a multicenter, randomized, open-label, blinded-endpoint clinical trial designed to evaluate the efficacy and safety of early administration of eptifibatide following intravenous thrombolysis in patients with acute…
- Trial name
- E-TWIST (NCT07347626)
- Testing
- Eptifibatide (Integrilin), Standard Medical Therapy
- Where
- 6 sites in China
- Volunteers
- 786 people
- Sponsor
- Xinqiao Hospital of Chongqing
Acute Ischemic Stroke, Intracranial Artery Occlusion
Rescue Stenting for Failed Endovascular Thrombectomy in Acute Ischemic Stroke (ReSET)
This study is a prospective, open-label, multi-center, registry study, designed to show that rescue stenting is safe and effective for emergency large vessel occlusion (ELVO) patients who have mechanical thrombectomy failure.
- Trial name
- NCT03993340
- Testing
- Rescue stenting
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Yonsei University
Atrial Fibrillation, Ischemic Stroke
Using 14-day Continuous Electrocardiography Patch Monitoring to Detect Paroxysmal Atrial Fibrillation After Stroke
In this prospective, single-center, open-label, non-randomized, single- arm, historically controlled study, we will compare the detection rate of paroxysmal atrial fibrillation in acute ischemic stroke patients without known…
- Trial name
- NCT05218473
- Testing
- Prolonged ECG monitoring, Conventional procedure group
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Ischemic Stroke, Acute
Electroacupuncture on Modifying Inflammatory Levels of Cytokines and Metabolites in Stroke Patients.
The study will make an association between the diagnosis of traditional Chinese medicine that establishes that the syndrome of blood stagnation generates alteration in blood flow, vascular dysfunction, and damage to the…
- Trial name
- NCT05734976
- Testing
- electroacupuncture
- Where
- Taiwan
- Volunteers
- 17 people
- Sponsor
- China Medical University Hospital
Stroke, Acute, Pulmonary Rehabilitation
Effect of Pulmonary Rehabilitation Program on Patients With Acute Ischemic Stroke, Mortality and Disability
Severe stroke remains an important cause of mortality and morbidity, despite advances in disease management, acute treatment and secondary measures.
- Conditions
- Stroke, Acute, Pulmonary Rehabilitation, Morality
- Trial name
- NCT04110652
- Testing
- pulmonary rehabilitation program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Acute Ischemic Stroke
Ischemic Post-conditioning in Acute Ischemic Stroke Thrombectomy
Ischemic post-conditioning is a neuroprotective strategy that has been proven to attenuate reperfusion injury in animal models of stroke.
- Trial name
- PROTECT (NCT05153655)
- Testing
- Local ischemic post-conditioning
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Capital Medical University
Ischemic Stroke, Hypothermia
Reperfusion With Cooling in Cerebral Acute Ischemia II
The purpose of this study is to determine whether reducing a patients body temperature (mild hypothermia of 33 degrees Centigrade) will significantly reduce the risk of brain injury (notably reperfusion injury and hemorrhagic…
- Trial name
- ReCCLAIM II (NCT01728649)
- Testing
- Mild Hypothermia
- Where
- United States
- Sponsor
- WellStar Health System
Acute Ischemic Stroke, Mechanical Thrombectomy
Rapid Local Ischemic Postconditioning in Acute Ischemic Stroke
The objective of this clinical trial is to determine whether rapid local ischemic postconditioning (RL-IPostC) is effective in preventing brain edema and safe in acute ischemic stroke (AIS) patients treated with mechanical…
- Conditions
- Acute Ischemic Stroke, Mechanical Thrombectomy, Ischemic Postconditioning, Brain Edema
- Trial name
- RAPID-SAVE (NCT06307743)
- Testing
- rapid local ischemic postconditioning
- Volunteers
- 135 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Stroke
Reduce Inefficiencies in Management of Spasticity
The purpose of this study is to evaluate the effectiveness of a spasticity screener and to determine if the spasticity screener results are useful to healthcare providers and impact clinical decision making
- Trial name
- ReIMage (NCT07639632)
- Testing
- Screener, Standard of care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
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