Clinical trials: Stroke, Cardiovascular
Stroke
The Efficacy of Acupuncture on Patients With First Acute Ischemic Stroke, With Signs of Hemiplegia and Hemiparesis
Chinese Acupuncture can improve the motor ability of patients after having first acute ischemic stroke, in time scale up to 3 weeks from when the ischemic stroke occur and in minimum receiving number of 3 Acupuncture treatments.
- Trial name
- NCT02612441
- Testing
- real Acupuncture Needles
- Where
- Israel
- Volunteers
- 2 people
- Sponsor
- Rambam Health Care Campus
Basilar Artery Occlusion, Acute Cerebrovascular Accident
Intravenous Tenecteplase Plus EVT Versus EVT Alone on 4.5 to 24 Hours After Basilar Artery Occlusion
To assess the effect of intravenous tenecteplase plus endovascular thrombectomy (EVT) compared to EVT alone on 4.5 to 24 hours after stroke due to basilar artery occlusion.
- Conditions
- Basilar Artery Occlusion, Acute Cerebrovascular Accident, Stroke Due to Basilar Artery Occlusion
- Trial name
- NCT05701956
- Testing
- Tenecteplase, Endovascular thrombectomy
- Where
- China
- Volunteers
- 330 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Carotid Stenosis, Coronary Artery Disease
Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk Patients
Prospective, single-center, clinical registry of patients with symptomatic/critical carotid artery stenosis at risk of stroke coexisting with unstable or multivessel severe coronary artery disease and/or severe valvular heart…
- Conditions
- Carotid Stenosis, Coronary Artery Disease, Valvular Heart Disease, Myocardial Infarction
- Trial name
- SIM-GUARD (NCT04973579)
- Testing
- Simutaneous (single anaesthesia) carotid artery stenting with MicroNet covered stent (CGuard) and cardiac surgery (CABG or surgical valve replacement / repair procedure)
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- John Paul II Hospital, Krakow
Carotid Stenosis
Risk Prediction Model for Cerebrovascular Events in Carotid Artery Stenosis
Atherosclerotic carotid artery stenosis is a major cause of stroke, and early identification of high-risk patients combined with surgical intervention can significantly reduce stroke risk.
- Trial name
- NCT06452173
- Testing
- Plasma, carotid high-resolution magnetic resonance imaging
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Dysphagia
The Use of Transcranial Direct Current Stimulation in the Rehabilitation of Post-Stroke Dysphagia During the Subacute Phase in Hospitalized Patients: A Randomized Clinical Trial
The purpose of this clinical trial is to determine whether the use of tDCS in dysphagia rehabilitation during the subacute phase of stroke assists in the recovery process while patients are still hospitalized.
- Trial name
- NCT07732673
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Juliane Lisboa Pereira
Stroke, Upper Limb Paresis
Video-based Training for Rehabilitation of Upper Limb Functions After Stroke
The study hypothesizes superiority of the video-based training (observation combined with motor exercise, "video") over motor exercise alone ("non-video") and standard rehabilitation ("standard").
- Trial name
- NCT01242956
- Testing
- verum group
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Dysphagia, Stroke
Reduction of Aspiration Through Cohesive Thin Liquids (CTL) in Patients With Mild Oropharyngeal Dysphagia
The aim of the trial is to identify any systematic effect of cohesiveness on the efficacy of swallowing in patients having dysphagia problems.
- Trial name
- NCT02522351
- Testing
- Cereal extract concentration 1, Cereal extract concentration 2, Cereal extract concentration 3
- Where
- 2 sites in Belgium, France
- Volunteers
- 35 people
- Sponsor
- Société des Produits Nestlé (SPN)
Acute Myocardial Infarction, Heart Failure
The Benefits of Wearable AI in Post-Discharge Management of AMI Patients
Myocardial infarction (MI) remains a major threat to human health. Although interventional treatment techniques have advanced rapidly, many patients still experience major adverse cardiovascular events (MACE) and require hospital…
- Trial name
- NCT07288229
- Testing
- Optimized Integrated Management Based on AI-Guided Wearable Data
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Stroke, Stroke, Acute Ischemic
NeuroAiD Patient-Reported Outcomes in Patients With Mild to Moderate Ischemic Stroke
This is a randomized, controlled, open-label study of MLC901 (NeuroAiD™ II) in patients with mild to moderate ischemic stroke. Eligible participants will be randomized in a 1:1 ratio to receive MLC901 in combination with standard…
- Conditions
- Stroke, Stroke, Acute Ischemic, Stroke, Ischemic, Stroke, Cryptogenic
- Trial name
- NAiD-PRO (NCT07828210)
- Testing
- MLC901, Standard treatment for acute ischemic stroke
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- EVD Pharmacy and Medical Company Limited
Stroke
Efficacy of Modified Constraint Induced Movement Therapy Combined With Threshold Electrical Stimulation in Stroke Patients
This study, it is aimed to investigate the effectiveness of applied modified constraint-induced movement therapy (MCIMT) with threshold electrical stimulation (TES) in addition to conventional therapy (therapeutic exercise…
- Trial name
- NCT05076123
- Testing
- Modified Constraint Induced Therapy and Threshold Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul Medeniyet University
Unilateral Spatial Neglect (USN)
Rehabilitation Methods for Unilateral Spatial Neglect in Stroke Patients
Stroke remains one of the leading causes of mortality and disability worldwide. Between 30% and 40% of patients who have had an acute cerebral hemorrhage, develop unilateral spatial neglect syndrome (USN).
- Trial name
- NCT06802159
- Testing
- Conventional therapy, Eye tracking based therapy, Cognitive therapy
- Where
- 2 sites in Russia
- Volunteers
- 30 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Stroke, Intracerebral Hemorrhage Basal Ganglia
Neuroendoscopic Hematoma Evacuation Combined With Methylprednisolone Sodium Succinate in the Treatment of Basal Ganglia Intracerebral Hemorrhage at the Early Stage
The aim of this trial is to investigate whether neuroendoscopic hematoma evacuation combined with early use of methylprednisolone sodium succinate can improve the efficacy and safety in the treatment with that of simple…
- Conditions
- Stroke, Intracerebral Hemorrhage Basal Ganglia, Methylprednisolone, Surgery
- Trial name
- NEMP-BGH (NCT06924983)
- Testing
- Simple neuroendoscopic hematoma evacuation, Neuroendoscopic hematoma evacuation combined with sodium methylprednisolone succinate
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yong Jiang
Blood Pressure, Stroke
Phone-based Intervention Under Nurse Guidance After Stroke 2
The overall objective of Phone-based Intervention under Nurse Guidance after Stroke II (PINGS-2) is to deploy a hybrid study design to firstly, demonstrate the efficacy of a theoretical-model-based, mHealth technology-centered…
- Conditions
- Blood Pressure, Stroke, Cardiovascular Diseases
- Trial name
- NCT04404166
- Testing
- PINGS 2, Standard of Care
- Where
- 10 sites in Ghana
- Volunteers
- 500 people
- Sponsor
- Northern California Institute of Research and Education
Stroke
The Effects of Vibration on Lower Limb Muscle Strength, Functional Status, and Psychological Health in Stroke Patients
The goal of this clinical trial is to the effect of vibration training on lower limb muscle strength, functional status and psychological health of stroke patients.
- Trial name
- NCT07333456
- Testing
- wearable vibration, vertical vibration, early rehabilitation
- Where
- Taiwan
- Volunteers
- 115 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Coronary Artery Disease, Ischemic Heart Disease
Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial
This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Non ST Segment Elevation Myocardial Infarction
- Trial name
- ECLIPSE (NCT03108456)
- Testing
- Orbital Atherectomy, Balloon
- Where
- 104 sites in United States
- Volunteers
- 2,005 people
- Sponsor
- Abbott Medical Devices
Stroke
Investigation of Activation of Latissimus Dorsi Muscle Segments During Functional Reach Activity in Chronic Stroke Patients
Latissimus Dorsi (LD); Medial sacrum, lumbar vertebrae and lower thoracic vertebrae 10-12 lateral to the spinous processus. It is a fan-like wide muscle that connects to the inferior angle of the scapula and ribs, adheres to the…
- Trial name
- NCT04181151
- Testing
- Electromyographic device
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cardiogenic Shock
Levosimendan Efficacy for Veno-arterial ECMO Weaning: a Retrospective Study
Failure of Weaning from ECMO is a serious complication, reaching an incidence between 29 and 58%. Inotrops are frequently used to help separating patient from ECMO.
- Trial name
- LEVO-ECMO (NCT03346824)
- Where
- France
- Volunteers
- 65 people
- Sponsor
- University Hospital, Strasbourg, France
Coronary Artery Disease, Myocardial Ischemia
Dual Therapy With Dabigatran/Ticagrelor Versus Dual Therapy With Dabigatran/Clopidogrel in ACS Patients With Indication for NOAC Undergoing PCI
A real world registry to compare dual therapy with Dabigatran/Ticagrelor to dual therapie with Dabigatran/Clopidogrel in patients with an indication for NOAC undergoing PCI in the setting of ACS.
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Myocardial Infarction, Atrial Fibrillation
- Trial name
- RE-DUAL PCI (NCT04688723)
- Testing
- Dabigatran + Ticagrelor, Dabigatran + clopidogrel
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Zuyderland Medisch Centrum
Stroke
Personalized Upper Extremity Rehabilitation for Persons With Stroke
Approximately 80% of individuals with chronic stroke present with long lasting upper extremity (UE) impairments. Advances in rehabilitation technology, such as robotics, virtual reality (VR) and neuromuscular electrical…
- Trial name
- SUPER (NCT03903770)
- Testing
- Upper extremity rehabilitation
- Where
- 2 sites in Canada
- Volunteers
- 32 people
- Sponsor
- McGill University
Cerebral Infarction
Sarpogrelate-Aspirin Comparative Clinical Study for Efficacy and Safety in Secondary Prevention of Cerebral Infarction (S-ACCESS)
Sarpogrelate (MCI-9042) is an antiplatelet drug that decreases 5-hydroxytryptamine (5-HT) levels in platelets via a blockade of 5-HT2 receptors; it has been used in atherosclerotic peripheral arterial disease.
- Trial name
- NCT00129805
- Testing
- MCI-9042, Aspirin
- Volunteers
- 1,510 people
- Sponsor
- Tanabe Pharma Corporation