Clinical trials: Stroke, Cerebral
Cardiovascular Diseases, Hypertension
Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
The CONNECT: "Developing a learning COmmunity to increase eNgagemeNt and Enrollment in cardiovascular Clinical Trials" is comprehensive, participant-centered learning platform designed to increase diversity in cardiovascular…
- Conditions
- Cardiovascular Diseases, Hypertension, Diabetes Type 2, Stroke
- Trial name
- CONNECT (NCT06347484)
- Testing
- EHR-informed Recruitment Method of Contact, Educational Text-Messages and Connection to Cardiovascular Research Opportunities
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Stroke, Obesity
Secondary Prevention of Stroke Through Non-drug Therapeutic Weight Reduction
SCENARIO is a trial to investigate the role of non-drug weight reduction in secondary prevention of stroke. It is a single-blinded, randomized, controlled multicentre trial with two arms.
- Trial name
- SCENARIO (NCT01721538)
- Testing
- Weight reduction program, Lecture on healthy nutrition
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Philipps University Marburg
Stroke Gait Rehabilitation
The Effect of Cupping on Spasticity and Function of the Lower Extremity During Rehabilitation After Stroke
Physical therapists use dry static cupping for the treatment of many conditions, including spasticity for patients post-stroke. While research better describes the effects of dry static cupping for patients with orthopedic…
- Trial name
- NCT06653855
- Testing
- Dry Static Cupping, Standard physical therapy treatment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Scott Getsoian
Stroke
The Beneficial Effects of Naps on Motor Learning
Background: Memory consolidation is the process by which memories become stable, long-term representations in the brain. Consolidation of a motor skill is dependent upon sleep.
- Trial name
- NCT04312126
- Testing
- MRI system, MEG system
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Immersive Care - Virtual Mirror Therapy
The purpose of this implementation study is - primarily - to investigate the feasibility, acceptability, tolerability of a new virtual reality application in stroke patients, and -secondarily - to gain initial insights in the…
- Trial name
- NCT04592757
- Testing
- Virtual mirror therapy via VR headset
- Where
- 2 sites in Belgium
- Volunteers
- 9 people
- Sponsor
- Thomas More University of Applied Sciences
Atrial Fibrillation, Stroke
Hemostatic Activity Following LAAO
The primary objective of this study is to prospectively investigate hemostatic activity following transcatheter left atrial appendage occlusion (LAAO).
- Trial name
- NCT05011981
- Testing
- Left Atrial Appendage Occlusion
- Where
- Denmark
- Volunteers
- 135 people
- Sponsor
- University of Aarhus
Ischemic Stroke
SITS (Safe Implementation of Treatments in Stroke) Open Artery by Thrombectomy in Acute Occlusive Stroke Study
Ischemic stroke, i.e. irreversible damage of a part of the patient's brain, is caused by the formation of blood clot in the major vessel which gives blood supply to a certain part of the brain.
- Trial name
- SITS Open (NCT02326428)
- Testing
- Stent retriever endovascular device for thrombectomy, Intravenous thrombolysis by alteplase (Actilyse) (optional)
- Where
- Sweden
- Volunteers
- 341 people
- Sponsor
- Karolinska Institutet
Stroke
Implementation of a HABIT-ILE Intervention at Home for Chronic Stroke
This study will use a randomized controlled trial design to assess the possible difference between two intensive treatment programs: a classic "Hand and Arm Bimanual Intensive Therapy Including Lower Extremities" (HABIT-ILE)…
- Trial name
- HABITILEhome (NCT05727111)
- Testing
- Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) implemented at the patient home, Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE), Follow-up Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) at the patient's home
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Université Catholique de Louvain
Stroke
Rivaroxaban Versus Aspirin in Secondary Prevention of Stroke and Prevention of Systemic Embolism in Patients With Recent Embolic Stroke of Undetermined Source (ESUS)
This is a study in patients who recently had a brain attack (stroke) and in whom no clear cause of the stroke could be identified.
- Trial name
- NAVIGATE ESUS (NCT02313909)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Acetylsalicylic acid (Aspirin, BAY1019036)
- Where
- 454 sites in United States, Argentina and 29 more
- Volunteers
- 7,213 people
- Sponsor
- Bayer
Upper Limb Rehabilitation, Stroke
Activities of Daily Living (ADL) Virtual Reality (VR) for Acquired Brain Injury (ABI) Upper-Limb Rehabilitation
Acquired brain injury (ABI) individuals have shown greater engagement and functional recovery when trained in virtual reality (VR)-assisted rehabilitation therapies.
- Trial name
- NCT07026630
- Testing
- Cooking In the Kitchen
- Where
- United States
- Sponsor
- Indiana University
Stroke Sequelae, Motor Disorders
Clinical Validation of a Hybrid BCI-controlled FES for Upper Limb Rehabilitation After Stroke
The RECOMMENCER project aims at developing and testing a novel hybrid Brain Computer Interface device based on cortico-muscular connectivity, that will be employed to activate Functional Electrical Stimulation (FES) of upper limb…
- Trial name
- RECOMMENCER (NCT05511207)
- Testing
- RECOM - hBCI training, CTRL - upper limb training with FES
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Donatella Mattia
Stroke, Acute, Stroke
Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke
Stroke is the leading cause of activity limitation among older adults in the United States. NeuroMuscular Electrical Stimulation (NMES) can assist stroke survivors in regaining motor ability and decreasing activity limitation…
- Conditions
- Stroke, Acute, Stroke, Hemiparesis
- Trial name
- NCT00142792
- Testing
- NMES device with EMG-triggered and Cyclic capabilities
- Where
- 3 sites in United States
- Volunteers
- 122 people
- Sponsor
- MetroHealth Medical Center
Ischemic Stroke, Thrombolytic (t-PA) Treatment
Long-Term Survival After Ischaemic Stroke: Ebrictus Study
A number of large trials have confirmed the benefits of thrombolysis in acute stroke, but there are gender differences. The authors sought to examine the relationship between sex and outcome after thrombolysis.
- Conditions
- Ischemic Stroke, Thrombolytic (t-PA) Treatment, Gender Bias, Long Term Adverse Effects
- Trial name
- EBRICTUS (NCT03247036)
- Testing
- IV thrombolytic (t-PA) treatment vs not
- Where
- Spain
- Volunteers
- 21,000 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Stroke
Adopting Dyad-focused Strategy Training to Stroke Survivors and Their Caregivers
The purpose of this study is to develop a dyad-focused intervention built upon the theoretical tenets of strategy training to help prepare stroke survivors and their caregivers to transit to community living.
- Trial name
- NCT05185271
- Testing
- Dyad-focused strategy training
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Stroke, Stroke Acute
Individual vs Co-Treatment in Acute Stroke Rehabilitation and Evaluation
This is a single center, pragmatic, randomized trial comparing the effectiveness of two commonly used approaches (co-treatment and individual treatment) in acute care rehabilitation.
- Trial name
- ICARE (NCT07411534)
- Testing
- Co-treatment, Individual Treatment
- Where
- United States
- Volunteers
- 567 people
- Sponsor
- Vanderbilt University Medical Center
Acute Ischemic Stroke
Reperfuse Ischemic Vessels With Endovascular Recanalization Device in JAPAN (RIVER JAPAN)
The main objective of this study is to document that the thrombectomy catheter (Rev-01) is effective and safe when used for revascularization in subjects with acute ischemic stroke within 8 hours of symptom onset who are…
- Trial name
- NCT01895634
- Testing
- Rev-01
- Where
- Japan
- Volunteers
- 49 people
- Sponsor
- Johnson & Johnson K.K. Medical Company
Atrial Fibrillation (AF)
Comparison of Different Pulsed Field Ablation Catheters in Atrial Fibrillation
Pulsed field energy ablation, a non-thermal ablation modality, can potentially reduce post-ablation tissue edema. Previous studies have confirmed the feasibility and safety of combined pulsed field ablation (PFA) and left atrial…
- Trial name
- COMBINATION 2P (NCT07036965)
- Testing
- CardiPulse, FaraPulse
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Hangzhou Dinova EP Technology Co., Ltd
Brain-injury, Stroke
Mechanical Ventilation in Brain-injured Patients
Protective ventilation (association of a tidal volume < 8 ml/kg with a positive end expiratory pressure) is poorly used in severe brain-injured patients.
- Conditions
- Brain-injury, Stroke, Subarachnoid Haemorrhage, Traumatic Brain Injury
- Trial name
- BI-VILI (NCT01885507)
- Testing
- Pass recommendations on ventilation factors and extubation
- Where
- 22 sites in France
- Volunteers
- 560 people
- Sponsor
- Nantes University Hospital
Stroke, Acute
Robot Mediated Therapy-Upper Limb Outcomes in Stroke
This study aims to determine the clinical outcomes of stroke patients who are provided with adjunctive robot-mediated task specific therapy(RMTT) and robot-mediated impairment training (RMIT) as compared to those who are provided…
- Trial name
- NCT05805644
- Testing
- Robot mediated upper limb therapy
- Volunteers
- 96 people
- Sponsor
- Changi General Hospital
Stroke Sequelae, Stroke
Mental Practice in Post-stroke Subjects
Among the limitations caused by cerebrovascular accident (CVA), the upper limb (MS) undergoes changes that limit the individual in his ability to maintain an active social life.
- Trial name
- NCT03251209
- Testing
- Physical practice, Mental practice, Videotherapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
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