Clinical trials: Stroke, Cerebral
Stroke, Aphasia
Study of the Participation of People With Aphasia Post Stroke and Their Caregivers in Valladolid Region (Spain)
The objective of this study is to determine the level of community participation of people with post-stroke aphasia and their caregivers, as well as the factors that facilitate or interfere with this participation in the…
- Trial name
- SPART-A (NCT06948721)
- Volunteers
- 50 people
- Sponsor
- Centro Integral de Rehabilitación
Traumatic and/or Non-traumatic Brain Injury
Assessing Special Features of Impaired Gait After Acquired Brain Injury With an Instrumented Treadmill
Hemiparetic gait following acquired brain injury (ABI) is grossly characterized by decreased speed of walking, increased stance time on the unaffected side, and decreased stance time on the affected side.These abnormalities are…
- Trial name
- NCT01413321
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Stroke
Energy Consumption and Cardiorespiratory Load During Robot-Assisted Gait Training in Non-Ambulatory Stroke Patients
The aim of this study will be to investigate the energy consumption, cardiorespiratory load and perceived exertion in non-ambulatory subacute stroke patients during a robot-assisted gait training (RAGT) session and to compare the…
- Trial name
- NCT02995616
- Testing
- Regular therapy settings, 100% guidance force, 60% guidance force
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Vrije Universiteit Brussel
Stroke
Neuromodulation and Dynamic Balance in Stroke
Portable Neuromodulation Stimulator (PoNS) is non-invasive stimulation device placed on the tongue to stimulate those brain regions understood to be important for maintaining balance.
- Trial name
- NCT05135533
- Testing
- Portable Neuromodulation Stimulation, Gait and balance training
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Medical University of South Carolina
Stroke, Fatigue Symptom
Physical Exercise as Treatment Post-stroke Fatigue - a Feasibilty Study.
The goal of this clinical trial is to evaluate the feasibility the treatment FaStEx (FatigueStrokeExercise) which consists of strength exercise in people with brain fatigue after stroke, referred to as post-stroke fatigue.
- Trial name
- NCT07206147
- Testing
- FaStEx - Structured strength training, Control group
- Where
- Sweden
- Volunteers
- 16 people
- Sponsor
- Region Örebro County
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)
This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis, stroke-like episodes (MELAS) and Leber's hereditary optic…
- Trial name
- NCT06792500
- Testing
- Glycerol Tributyrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- George Washington University
Acute Ischemic Stroke
Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke
Many patients with acute ischemic stroke are ineligible for currently available standard treatments (clot-busting medication, also known as intravenous thrombolytic or mechanical removal of a clot), and many are non-responders…
- Trial name
- TESSERACT 2 (NCT06440707)
- Testing
- High-definition Cathodal Transcranial Direct Current Stimulation (HD C-tDCS)
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Infarction, Middle Cerebral Artery, Infarction, Anterior Cerebral Artery
Effect of Mesenchymal Stem Cells(MSCs) Transplantation for Acute Cerebral Infarction Patients
This is a placebo controlled, randomized, double blinded study including Phase 1 and Phase 2. Phase I study is a safety assessment and Phase 2 study is incline to assess effectiveness of MSCs.
- Conditions
- Infarction, Middle Cerebral Artery, Infarction, Anterior Cerebral Artery, Cerebral Infarction, Stroke, Ischemic
- Trial name
- NCT04093336
- Testing
- human umbilical cord mesenchymal stem cells, standardized treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai East Hospital
Stroke, Aphasia
Studying Language With Brain Stimulation in Aphasia
The overall goal of this study is to evaluate whether stimulation of two brain areas alongside behavioral speech-language therapy increases connectivity to improve language functions in stroke-aphasia patients.
- Trial name
- NCT05660304
- Testing
- Cortico-cortical paired associative stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Stroke
Efficacy of the Non-invasive Brain Stimulation Techniques for Lower Limb Recovery in Stroke Patients
This study is to compare the efficacy of two types of non-invasive brain stimulation (NIBS) in lower limb motor function recovery in stroke patients.
- Trial name
- NCT02920333
- Testing
- conventional rehab training, tDCS, rTMS
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Stroke, Chronic Stroke
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
The central objective of this application is to explore the neural substrate of personalized tDCS (ptDCS) and to determine whether the paradigm for each stroke patient can predict the amount of sustained clinical improvement…
- Conditions
- Stroke, Chronic Stroke, Hemorrhage Brain, Ischemic Stroke
- Trial name
- NCT06286800
- Testing
- Transcranial direct current stimulation (tDCS) with OT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Methodist Hospital Research Institute
Perceptual Disorders, Stroke
Neurobiomarker for Prism Adaptation Treatment Response
Preliminary data will be collected about which individuals with spatial neglect from right hemisphere stroke (aiming vs perceptual neglect) improve with Prism Adaptation Training and if there is a particular pattern of damage in…
- Conditions
- Perceptual Disorders, Stroke, Biomarker
- Trial name
- NCT04966000
- Testing
- Prism Adaptation Therapy
- Where
- United States
- Sponsor
- University of Utah
Acute Ischemic Stroke
Hemodynamic Optimization of Cerebral Perfusion After Endovascular Therapy in Patients With Acute Ischemic Stroke
Mechanical thrombectomy is a very effective treatment in patients who have suffered an acute ischemic stroke associated with intracranial large vessel occlusion.
- Trial name
- HOPE (NCT04892511)
- Testing
- Adjusted medication
- Where
- Spain
- Volunteers
- 814 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Stroke
RIsk of Apoplexia Cerebri in CLOpidogrel Non-responders
Stroke patients are given prophylactic treatment with clopidogrel to prevent new strokes. Some of these patients (the investigators don't know precisely how many, but previous studies indicate 4-34%) are so called non-responders…
- Trial name
- RISCLON (NCT02093299)
- Testing
- Clopidogrel
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- Zealand University Hospital
Stroke
A Rehabilitation Therapy for Post-stroke Fatigue
Stroke is a leading cause of adult disability in the community. Fatigue affects about a third of stroke survivors. It results in difficulty taking part in everyday activities, and increases risk of hospitalization and death after…
- Trial name
- NCT02131532
- Testing
- A brief psychological intervention
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Edinburgh
Atrial Fibrillation, Ischemic Stroke
Precision Medicine in Ischemic Stroke and Atrial Fibrillation
The overall goal of this study is to minimize morbidity due to Atrial Fibrillation (AF). The specific objective is to develop and implement a rational and personalized approach to AF risk estimation that can inform management…
- Trial name
- PreMISe-AF (NCT04637087)
- Testing
- Atrial fibrillation risk electronic health record alert
- Where
- United States
- Volunteers
- 805 people
- Sponsor
- Massachusetts General Hospital
Post Stroke
Perception of Advanced Rehabilitation Technologies Among Post-Stroke Patients and Rehabilitation Staff
This observational study aims to assess the perception of advanced rehabilitation technologies among three key groups involved in stroke recovery: post-stroke patients, physicians specialized in Physical and Rehabilitation…
- Trial name
- P-TECH-AVC (NCT06986421)
- Testing
- completion of a structured questionnaire
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Brain Health
Brain Health in the Time of COVID-19
This is a nationwide research program to study the neurological effects of COVID-19. It is open to the public. Healthy individuals and individuals who are or have been infected with COVID-19 are encouraged to join the effort.
- Trial name
- NCT04438967
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Miro Health
Stroke
Randomized Trial of Transcranial Theta-burst Stimulation and Transcranial Direct Current Stimulation
Background: Stroke is a leading cause of adult disability. Non-invasive brain stimulation can induce significant and sustained improvements in functional outcome.
- Trial name
- NCT02031107
- Testing
- cTBS, cathodal tDCS
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- Adrian Guggisberg
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