Clinical trials: Stroke, Cerebral
Acute Ischemic Stroke, Vessel Occlusion
REal-World Analyses of Stroke - Thrombus Occlusion REtrieval
To collect real-world evidence allowing assessment of functional, imaging, and safety outcomes of MicroVention market-released acute ischemic stroke devices when used at the direction of the treating physician.
- Conditions
- Acute Ischemic Stroke, Vessel Occlusion, Stroke, Ischemic
- Trial name
- "RESTORE" (NCT04451525)
- Testing
- MicroVention Mechanical Thrombectomy Devices as first-line treatment
- Where
- 37 sites in United States
- Volunteers
- 710 people
- Sponsor
- Microvention-Terumo, Inc.
Brain Ischemia
Magnetic Resonance Imaging to Investigate Silent Strokes During Neck and Skull Angioplasty
This study will use magnetic resonance imaging (MRI) to determine if silent strokes occur during angioplasty of the blood vessels in the neck or skull.
- Trial name
- NCT00015717
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Acute Stroke
Evaluate the Safety and Explore Efficacy of Umbilical Cord Mesenchymal Stem Cells in Acute Ischemic Stroke
This study is a first-in-human assessment of safety of using umbilical cord mesenchymal stem cells (UCMSCs) in patients with Acute Ischemic Stroke via a combination of intra arterial (IA) and intravenous (IV) stem cell…
- Trial name
- NCT04434768
- Testing
- UMSC01
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Ever Supreme Bio Technology Co., Ltd.
Stroke, Cognitive and Attention Disorders and Disturbances
The RenAtt Method for Diagnosing and Treating Attention Problems After Stroke and Brain Injury, Further Validation of RehAtt® DiSTRO Assessment of Cognitive and Visual Function
Stroke is one of the most common long-term disabilities in the world. Despite better access to more effective acute treatment, WHO reports a prediction of almost a doubling of disability-adjusted life-years (DALYs) in 2050.
- Conditions
- Stroke, Cognitive and Attention Disorders and Disturbances, Digital Health, Screening Strategy
- Trial name
- NCT07762274
- Testing
- Oxford Cognitive Screen
- Where
- 3 sites in Italy, Sweden and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Umeå University
Dysphagia After Stroke, Aspiration Pneumonias
Tongue Brush (Orabrush) for Reducing Aspiration Pneumonia in Stroke Patients
The investigators conduct a controlled prospective experimental intervention study to examine whether the use of a tongue brush (Orabrush) can improve the rate of aspiration pneumonia and dysphagia in patients with ischemic…
- Conditions
- Dysphagia After Stroke, Aspiration Pneumonias, Ischemic Stroke
- Trial name
- StrOra (NCT06765018)
- Testing
- Tongue Brush (Orabrush)
- Where
- Germany
- Volunteers
- 252 people
- Sponsor
- University Hospital Marburg
Cerebral Stroke, Malondialdehyde
Effect of Astaxanthin Supplementation on Plasma Malondialdehyde Levels and NIHSS of Stroke Patients
This is an interventional randomized, controlled trial in analyzing the effects of astaxanthin supplementation on plasma malondialdehyde levels and NIHSS of acute ischemic stroke patients.
- Conditions
- Cerebral Stroke, Malondialdehyde, Oxidative Stress
- Trial name
- NCT03945526
- Testing
- Astaxanthine
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Universitas Indonesia
Stroke
Comparing Mirror Therapy and CIMT for Hand and Arm Function in Post-Stroke Patients
The goal of this clinical trial is to find out whether Mirror Therapy (MT) combined with Constraint-Induced Movement Therapy (CIMT) improves hand and arm function after a stroke.
- Trial name
- NCT07139015
- Testing
- CONSTRAINT-INDUCED MOVEMENT THERAPY, MIRROR THERAPY
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Cerebral Stroke
FitMi Plus Home Therapy for Stroke Patients
The investigators will investigate the efficacy of a newly developed functional exercise device (FitMi Plus) for people in the chronic stage after a stroke compared to the FitMi Basic (i.e. without functional exercises).
- Trial name
- NCT03935425
- Testing
- FitMi Plus, FitMi Basic
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Flint Rehabilitation Devices, LLC
Stroke
A Self-efficacy Enhancing Stroke Self-management Program for Community-dwelling Stroke Survivors
The aim of this study is to examine the effectiveness of a nurse-led self-efficacy enhancing stroke self-management program on recovery of community-dwelling stroke survivors.
- Trial name
- SESSMP (NCT02112955)
- Testing
- Stroke self-management program, Usual care
- Where
- 3 sites in Hong Kong
- Volunteers
- 128 people
- Sponsor
- Queensland University of Technology
Ischemic Stroke, Coronary Heart Disease
Safety Study of Dengzhanxixin (a Chinese Medicine Injection) Used in Hospitals in China
This study was advocated by Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences in October 2011.
- Trial name
- NCT01612585
- Volunteers
- 30,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Stroke
AI-assisted Continuous Stratification in Neurorehabilitation of Stroke Using Personalized Digital Twins
The goal of this clinical trial is to learn if a rehabilitation application on a smartphone, an app, can be used by adults who have had a stroke.
- Trial name
- STRATIF-AI (NCT07488143)
- Testing
- Smartphone rehabilitation application "app"
- Volunteers
- 30 people
- Sponsor
- University of Leeds
Elderly, Atrial Fibrillation (AF)
Low Dose Edoxaban in Elderly Patients With AF and a History of Stroke
This prospectively enrolled, pragmatic randomized trial aims to investigate whether very low dose edoxaban regimen (15 mg daily) achieves similar edoxaban concentrations as low dose edoxaban regimen (30 mg daily), while…
- Conditions
- Elderly, Atrial Fibrillation (AF), Ischemic Stroke
- Trial name
- LEAVE-Stroke (NCT06900725)
- Testing
- edoxaban, Edoxaban 30 mg
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Cerebral Stroke
Facilitating Implicit Learning to Improve Neurorehabilitation in Stroke
Stroke is one of the leading causes of chronic disability in Veterans. Stroke is associated with significant loss of mobility, increased risk of falling, cardiovascular disease, depression and neuro-cognitive impairment.
- Trial name
- NCT02017574
- Testing
- Reaching Task
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Intracranial Aneurysm, Subarachnoid Hemorrhage
Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial
Aneurysmal subarachnoid hemorrhage (SAH) is a form of stroke in which secondary neurological deterioration is an important cause of mortality and morbidity.
- Trial name
- DASH (NCT02875262)
- Testing
- Deferoxamine
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Stroke, Stroke Sequelae
The StrokeCog Study: Cognitive Rehabilitation Intervention in Stroke
This study aims to progress to the next stage of feasibility testing, by conducting a pilot randomised controlled study with consecutive stroke patients who have mild to moderate cognitive impairment following stroke.
- Conditions
- Stroke, Stroke Sequelae, Cognitive Impairment
- Trial name
- StrokeCog-R (NCT06021470)
- Testing
- Cognitive rehabilitation intervention
- Volunteers
- 64 people
- Sponsor
- Royal College of Surgeons, Ireland
User of an Upper Limb Assistance Device, User Experience
Impact Study on Users of Upper Limb Assistive Devices
This impact study of upper limb (UL) assistance devices is part of the Exploratory PEPR O2R "Robotic assistance for human movements." The integrated project PI3 "ASSISTMOV," composed of a multidisciplinary team in engineering and…
- Conditions
- User of an Upper Limb Assistance Device, User Experience, Post-stroke, Spinal Cord Injury
- Trial name
- AMUSE (NCT07429188)
- Testing
- interviews and questionnaires
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Association APPROCHE
Stroke, Ischemic Stroke
Clinician JUdgment Versus Risk Score to Predict Stroke outComes: The JURASSIC Clinical Trial
Background: Several risk score models are now available to assist clinicians estimate outcomes after an acute ischemic stroke. Limited information is available on the predictive value of these scores compared to real outcomes and…
- Conditions
- Stroke, Ischemic Stroke, Cerebrovascular Disease
- Trial name
- JURASSIC (NCT01657279)
- Testing
- Clinical scenarios
- Where
- 4 sites in United States, Canada
- Volunteers
- 111 people
- Sponsor
- Unity Health Toronto
Acute Stroke
Which Factors Influence the Duration and the Success of Mechanical Thrombectomy During the Acute Phase of Cerebral Infarction?
This study aims to identify factors influencing the time span and success of reperfusion after a mechanical thrombectomy in the acute phase of cerebral infarction, and in particular the effect of intra-venous thrombolysis.
- Trial name
- REPAIR-FC (NCT03451903)
- Testing
- Actilyse, Mechanical thrombectomy
- Volunteers
- 106 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Atrial Fibrillation
The Role of Multimodality Imaging in Left Atrial Appendage Closure
The aim of the present prospective, randomized single-centre study is to examine the success rate, safety, overall preoperative and operative burden and long-time outcome of percutaneous left atrial appendage closure procedures…
- Trial name
- MILAAC (NCT04800913)
- Testing
- Multimodal imaging, Standard imaging
- Where
- Hungary
- Volunteers
- 44 people
- Sponsor
- Hungarian Institute of Cardiology
Stroke
Transcranial Direct Current Stimulation in Acute Ischemic Stroke Treatment
This prospective interventional single center randomized sham controlled dose-escalation study will assess safety, tolerability, feasibility and potential efficacy of transcranial direct current stimulation (tDCS) in acute stroke…
- Trial name
- DICAST-SF (NCT04801446)
- Testing
- Soterix Medical 1X1 tDCS stimulator (active C-tDCS)
- Where
- Czechia
- Volunteers
- 25 people
- Sponsor
- General University Hospital, Prague
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