Clinical trials: Stroke, Cerebral
Ischemic Stroke, TIA
Cilostazol and Aspirin in Stroke and TIA
This study is a randomized, open-labelled trial. We randomly assigned patients within 24 hours after the onset of minor ischemic stroke or high-risk TIA to combination therapy with cilostazol and aspirin or to clopidogrel plus…
- Trial name
- NCT06522113
- Testing
- Cilostazol, Clopidogrel
- Where
- South Korea
- Volunteers
- 378 people
- Sponsor
- Incheon St.Mary's Hospital
Aphasia, Acquired, Aphasia
Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia
The goal of this clinical trial is to establish the feasibility and fidelity of a high-intensity exercise program for individuals with post-stroke aphasia.
- Conditions
- Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia Non Fluent
- Trial name
- NCT06185023
- Testing
- Low-intensity physical exercise, High-intensity physical exercise
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of California, Berkeley
Stroke
Low-frequency Transcranial Magnetic Stimulation To Enhance Motor Recovery In The Subacute Phase After Stroke
Low-frequency repetitive transcranial magnetic stimulation (rTMS) of the unaffected hemisphere (UH) transiently improves motor function in patients in the chronic phase after stroke.
- Trial name
- NCT01333579
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke Patients With Symptomatic Intracranial Atherosclerotic Stenosis
Evolocumab Added to Statin Therapy in Symptomatic Intracranial Atherosclerotic Stenosis (EAST-ICAS)
The primary goal of the trial is to investigate whether the experimental arms (receiving the Proprotein Convertase Subtilisin-Kexin Type 9 [PCSK9] inhibitor Evolocumab plus statin) could cause more changes from baseline in…
- Trial name
- EAST-ICAS (NCT05741086)
- Testing
- Evolocumab, Atorvastatin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Stroke
Active Smart Wearable Orthosis for Enhanched Rehabilitation THErapy
The purpose of this study is to investigate the usability of a new upper limb robot assisted therapy device in stroke patients.
- Trial name
- ARTHE (NCT03153254)
- Testing
- Test upper limb robot assisted therapy device, Training with new upper limb robot assisted therapy device
- Where
- 4 sites in Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas More Kempen
Dyslexia, Acquired, Brain Injuries
Therapy for Reading Problems in Adults After Brain Injury
Adults who sustain brain damage due to stroke, head injury, or traumatic surgery may develop difficulty reading. This study examines the effectiveness of behavior-based programs to improve reading ability in these individuals.
- Conditions
- Dyslexia, Acquired, Brain Injuries, Cerebrovascular Accident
- Trial name
- NCT00064805
- Testing
- Cognitive Therapy to Improve Reading
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stroke, Hemiplegia
Cardiovascular Function in Sub Maximal Exercise and Performance in Three Daily Activity Tests After Stroke
The purpose of this study is to explore the relationship between cardiovascular function of persons with post stroke conditions and their performance in three field tests.
- Trial name
- NCT01396746
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hillel Yaffe Medical Center
Stroke, Ischemic Stroke
Feasibility of a First-Line Physical Activity Intervention After Stroke
The goal of this study is to explore a new intervention that supports physical activity within the first 6 weeks after stroke. All participants will complete assessments at weeks 0 and 7.
- Conditions
- Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- PA-ChatS (NCT06679803)
- Testing
- Physical Activity Chats after Stroke (PA-ChatS)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Minnesota
Chronic Stroke
Differential Effectiveness of Robotic Assisted Therapy on Upper Extremity Function in Patients With Chronic Stroke
The objectives of this study are to: determine the effects of exoskeleton vs. end effector training systems on upper extremity motor and physiological function, daily functions, quality of life and self-efficacy in patients with…
- Trial name
- NCT04260061
- Testing
- training systems
- Where
- Taiwan
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Cerebrovascular Disorders
Transcranial Direct Current Stimulation Associate to Constraint Induced Movement Therapy Over Premotor Cortex in Severe Stroke
The purpose is to compare the effects of tDCS and constraint induced movement therapy (CIMT) in the premotor cortex vs. primary motor cortex in severely subacute stroke survivors.
- Conditions
- Stroke, Cerebrovascular Disorders, Cerebral Infarction
- Trial name
- NCT02628561
- Testing
- Transcranial direct current stimulation, Constraint-Induced Movement Therapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Paraíba
Chronic Stroke Patients, Lower Extremity
Evaluation of Lower Extremity Interventions in Individuals With Chronic Stroke
This study aims to evaluate the effectiveness of closed kinetic chain (CKC) exercises and kinesio taping on knee joint proprioception, balance, functional performance, and quality of life in individuals with chronic stroke.
- Conditions
- Chronic Stroke Patients, Lower Extremity, Knee Proprioception, Closed Kinetic Chain Exercises
- Trial name
- NCT07258342
- Testing
- Measurement of Knee Joint Position Sense, Berg Balance Scale (BDS), Timed Up and Go Test (TUG)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Stroke
Atrial Cardiomyopathy in Patients With Stroke of Undetected Mechanism
The goal of this study is to evaluate left atrial structural and functional abnormalities in stroke of undetected mechanism and atherosclerotic stroke with cardiac MRI.
- Trial name
- NCT03830983
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Stroke
A Caregiver-mediated Intervention Improves the Functional Ability of Home-living Chronic Stroke Patients
To examine the feasibility of improving stroke patients' physical functional recovery and social participation through improving caregiver's care capability.
- Trial name
- NCT01693341
- Testing
- Care-giver mediated training
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Asia University
Ischemic Stroke
Efficacy and Safety Evaluation of 3K3A-APC in Ischemic Stroke
The purpose of this study is to evaluate the efficacy and safety of intravenous doses of 3K3A-APC, a recombinant variant of human activated protein C (APC), in the treatment of acute ischemic stroke following treatment with…
- Trial name
- RHAPSODY-2 (NCT05484154)
- Testing
- 3K3A-APC
- Sponsor
- ZZ Biotech, LLC
Being Between 40-80 Years Old, Being Diagnosed With Haemiplegia
The Relationship Between Lower Limb Functionality, Foot Joint Position Sensation and Balance in Haemiplegic Patients
Stroke is defined as a neurological disorder resulting from acute focal damage to the central nervous system caused by vascular factors, which may include cerebral infarction, intracerebral haemorrhage and subarachnoid…
- Conditions
- Being Between 40-80 Years Old, Being Diagnosed With Haemiplegia, Getting 20 Points or More in the Mini Mental Test, Volunteering to Participate in the Study
- Trial name
- NCT06043960
- Testing
- Humac Norm İsokinetic Machine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Stroke
Measurement of Cerebral Oxygen Extraction Fraction Using MRI Technique
All images in this study were acquired on a 1.5 T Sonata whole body scanner (Siemens Medical Inc., Erlangen, Germany) using 2D multi-echo gradient echo/spin echo sequence and 2D single-shot gradient echo-planar imaging sequence…
- Trial name
- NCT00166920
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ischemic Stroke, Hemorrhagic Stroke
A Novel Transition Program to Reduce Disability After Stroke
This study evaluates a program designed to help individuals transition home from inpatient rehabilitation following an ischemic or hemorrhagic stroke.
- Trial name
- COMPASS (NCT03485820)
- Testing
- COMPASS, Stroke education
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Washington University School of Medicine
Acute Ischemic Stroke
Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events(TRACE)
To explore the safe and efficacious dose of rhTNK-tPA injection administered within 3 hours after onset of hyperacute ischemic stroke; to provide dose evidence for phase III clinical trial.
- Trial name
- NCT04676659
- Testing
- TNK-tPA
- Where
- 24 sites in China
- Volunteers
- 240 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Ischemic, Cerebrovascular Accident
The Effects of Blood Flow Restriction With Low-intensity Resistance Training Versus Traditional Resistance Exercise on Lower Limb Strength, Walking Capacity, and Balance in Patients With Ischemic Stroke: (BFR-Stroke RESILIENCE Trial)
Stroke is the leading neurological disease in the world that causes long-term disability. The most common cause of disability after stroke is motor impairment resulting from brain damage which ultimately causes mobility and…
- Trial name
- NCT05281679
- Testing
- Low-intensity resistance exercise with blood flow restriction group (L-BFR), High-intensity resistance exercise without blood flow restriction group (H-BFR).
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University - Cerrahpasa
Ischemic Stroke, Acute
Accuracy of Transcranial Colour Coded Duplex in Comparing With CT Angiography
Investigator will compare accuracy of transcranial colour coded duplex with CT angiography in detecting arterial obstructions in patients presenting or with history of cerebrovascular ischemic strokes
- Trial name
- NCT06920303
- Testing
- transcranial colour coded duplex
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
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