Clinical trials: Stroke, Cerebral
Sickle Cell Anemia in Children
Stroke Prevention With Hydroxyurea Enabled Through Research and Education (SPHERE)
This study will 1) Evaluate the prevalence of elevated (conditional or abnormal) transcranial Doppler (TCD) velocities in a cross-sectional analysis of children with Sickle Cell Anemia (SCA) living in Tanzania; 2) Obtain…
- Trial name
- NCT03948867
- Testing
- Hydroxyurea, Elevated Arm TCD Examination, Normal Arm TCD Examination
- Where
- 2 sites in United States, Tanzania
- Volunteers
- 202 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Ischemic Stroke
The Efficacy of a Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Subacute Ischemic Stroke Patients - a Pivotal Study (THE "EMAGINE" STUDY)
This is a multicenter study that will be conducted at approximately 20 centers. BQ 2.0 is a wearable medical device that produces and delivers non-invasive, extremely-low-intensity and low-frequency, frequency-tuned…
- Trial name
- BQ5 (NCT05044507)
- Testing
- BQ 2.0
- Where
- 15 sites in United States
- Volunteers
- 100 people
- Sponsor
- BrainQ Technologies Ltd.
Ventilator Associated Pneumonia ( VAP)
Role of Inhaled Polymyxin as an Adjunct to Intravenous Therapy in Multidrug Resistant Ventilator-associated Pneumonia in Stroke Patients
This study investigates whether adjunctive inhaled colistin enhances clinical recovery and microbiological clearance in multidrug resistant ventilator-associated pneumonia in stroke patients
- Trial name
- NCT07865871
- Testing
- Inhaled colistin, Saline
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Stroke
Sit-to-stand Training in Stroke Patient
Background: It is unknown whether the self-initiated sit-to-stand training with assistive device is effective to regain the independence of sit-to-stand in stroke patients.
- Trial name
- NCT03273101
- Testing
- Mechanical assisted sit-to-stand training group, Manual assisted sit-to-stand training group
- Volunteers
- 52 people
- Sponsor
- Tai Po Hospital
Acute Ischemic Stroke
SELECT2: A Randomized Controlled Trial to Optimize Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke
SELECT 2 evaluates the efficacy and safety of endovascular thrombectomy compared to medical management alone in acute ischemic stroke patients due to a large vessel occlusion in the distal ICA and MCA M1 who have large core on…
- Trial name
- SELECT2 (NCT03876457)
- Testing
- Endovascular Thrombectomy, Medical Management
- Where
- 31 sites in United States, Australia and 4 more
- Volunteers
- 352 people
- Sponsor
- University Hospitals Cleveland Medical Center
Cognitive Impairment, Stroke
SMARTease Trial: Evaluating Stroke Help Distance Interventions to Improve Cognitive Performance Post-Stroke
The purpose of this study is to provide evidence for the feasibility and initial effectiveness of a manualized, telephone-based (telehealth) approach to the delivery of cognitive interventions (SMARTease) targeted to improve…
- Trial name
- SMARTease (NCT01407081)
- Testing
- Telerehabilitation Cognitive Strategy Training
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Nova Scotia Health Authority
Stroke, Hemiparesis After Stroke
Prospective Real-World Evidence Study of the IpsiHand® System in Adult Stroke Survivors
This study focuses on monitoring real-world customers who have been prescribed the IpsiHand® as part of their rehabilitation post-stroke.
- Conditions
- Stroke, Hemiparesis After Stroke, Brain Computer Interface
- Trial name
- NCT07147881
- Testing
- IpsiHand
- Volunteers
- 100 people
- Sponsor
- Neurolutions, Inc.
Chronic Stroke
Game-Based Home Exercise Programs in Chronic Stroke: A Feasibility Study
Study will look at the effect of a game-based, task-oriented home exercise program on adherence in persons with chronic (> 6 months post) stroke as compared to a standard home exercise program.
- Trial name
- NCT03531567
- Testing
- Virtual Reality Mystic Isle Game, Standard Home Exercise Program
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Missouri-Columbia
Stroke, Hemiparesis
Proprioceptive Stimulation With Manual Bilateral Rhythmic Exercise in Post-stroke Patients
The purpose of this study is to evaluate the effect of the repetitive proprioceptive bilateral stimulation for the early recovery of the voluntary muscle contraction in stroke patients.
- Trial name
- BAT (NCT03155399)
- Testing
- Proprioceptive based training (PBT), Conventional neuromotor treatment (CNT).
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Acute Ischemic Stroke
Identification of Stroke Patients ≤ 3 and ≤ 4.5 Hours of Symptom Onset by Fluid Attenuated Inversion Recovery (FLAIR) Imaging and Diffusion Weighted Imaging (DWI)
The aim of the study is to evaluate the use of combined fluid attenuated inversion recovery (FLAIR) imaging and diffusion weighted imaging (DWI) as surrogate marker of lesion age within the first 6 hours of ischemic stroke in…
- Trial name
- PRE-FLAIR (NCT01021319)
- Where
- 2 sites in Germany
- Volunteers
- 643 people
- Sponsor
- Götz Thomalla, MD
Stroke Syndrome
The Effect of Mirror Therapy With Virtual Reality Application on Motor-Sense Acquisition and Quality of Live in Home Care of Stroke Patients
: Aim: Stroke is increasing day by day in our country as in the world. Early rehabilitation after stroke accelerates motor-sensory gains of individuals. This also increases the quality of life.
- Trial name
- NCT05624892
- Testing
- Mirror Therapy with Virtual Reality Application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Hemodynamic Instability, Anesthesia, General
Hemodynamics During Induction of General Anesthesia With Medium or Low Remifentanil Doses.
In this trial the investigators want to examine if there is any difference in hemodynamic stability during induction when comparing two low and a medium remifentanil dose and keeping propofol induction dose at about 2.0 mg/kg.
- Conditions
- Hemodynamic Instability, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- RH (NCT03861377)
- Testing
- Remifentanil R2, Remifentanil R4, Remifentanil R8
- Where
- Norway
- Volunteers
- 99 people
- Sponsor
- Helse Fonna
Stroke, Acute Traumatic Brain Injury
Clinimetric Application of FOUR Scale as in Treatment and Rehabilitation of Patients With Acute Cerebral Injury
The aim of this study is to increase the effectiveness of clinical monitoring of patients with acute cerebral insufficiency by improving the discriminative ability of the FOUR scale.
- Conditions
- Stroke, Acute Traumatic Brain Injury, Subarachnoid Hemorrhage
- Trial name
- FOURACI (NCT06043167)
- Testing
- The predictive value russian rendition the FOUR score.
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Surgut Clinical Trauma Hospital
Stroke
Telehealth Intervention Involving HEARTS Technical Package and Activity Monitor to Promote Physical Activity Post-stroke
Objectives: The aim of this feasibility randomized controlled trial (RCT) study is to investigate whether the theoretically informed telehealth intervention involving the HEARTS Technical Package and the use of an activity…
- Trial name
- NCT06068036
- Testing
- Telehealth intervention: HEARTS technical package + activity monitor (Smartwatch Mi Band 7®), Telehealth intervention: HEARTS technical package
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Federal University of Minas Gerais
Stroke, Physical Disability
Robotic Versus Conventional Therapy For Post-Stroke Hand Motoric Recovery
This clinical trial aims to compare the effectiveness of Robotic versus conventional mirror therapy among post-stroke patients. The main questions it aims to answer are: Effectiveness of both interventions in hand motoric…
- Conditions
- Stroke, Physical Disability, Upper Extremity Paresis
- Trial name
- NCT06155058
- Testing
- SYREBO, Conventional Mirror Method
- Where
- 3 sites in Indonesia
- Volunteers
- 40 people
- Sponsor
- Hasanuddin University
Basilar Artery Occlusion
OUTCOME AND SAFETY OF RECANALIZATION TREATMENTS IN ISCHEMIC STROKE DUE TO ACUTE BASILAR ARTERY OCCLUSION
Rationale: Recently, two prospective multicenter RCT reported a potential beneficial effect of endovascular thrombectomy (EVT) in patients with an acute symptomatic basilar artery occlusion (BAO).
- Trial name
- NCT05402878
- Where
- Vietnam
- Volunteers
- 150 people
- Sponsor
- 115 People's Hospital
Stroke, Atrial Fibrillation
Differences in ECG- vs. proLonged cardIac MonItor-DeTected Atrial Fibrillation in STROKE Patients (DELIMIT AF-STROKE)
The present study is an investigator-initiated, single-center, retrospective study based on data from the London Ontario Stroke Registry (LOSR), aiming to compare the characteristics and outcomes of ECG-detected and…
- Conditions
- Stroke, Atrial Fibrillation, TIA
- Trial name
- NCT05822791
- Testing
- Prolonged cardiac monitoring, ECG
- Where
- Canada
- Volunteers
- 366 people
- Sponsor
- Luciano A. Sposato
Ischemic Stroke, Covid 19
Endovascular Thrombectomy in COVID-19 Infected Patients
About 5% of COVID-19 patients may present symptoms related to acute ischemic stroke (AIS). Treatment-management and outcomes related to mechanical thrombectomy (MT) for COVID-19 infected patients harboring large vessel occlusion…
- Trial name
- ET-COVID-19 (NCT04406090)
- Testing
- Mechanical Trombectomy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Stroke
Efficacy and Acceptability of the Luna EMG Rehabilitation Robot on Motor Recovery of the Upper Limb in the Chronic Phase of Stroke
Recent work on large cohorts of chronic stroke (>6 months post-stroke) have shown that intensive training of the upper limb in the chronic stroke patients can lead to substantial motor and functional gains that are maintained at…
- Trial name
- LUNASTROKE (NCT05902910)
- Testing
- LUNA-EMG Robot
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Brest
Carotid Artery Disease, Stroke
Carotid Artery Stenting Outcomes in the Standard Risk Population for Carotid Endarterectomy
The objective of the CANOPY trial is to assess the continued safety and effectiveness of the RX Acculink Carotid Stent System under commercial use in subjects at standard risk for adverse events from Carotid Endarterectomy (CEA)…
- Conditions
- Carotid Artery Disease, Stroke, Amaurosis Fugax, Transient Ischemic Attack (TIA)
- Trial name
- CANOPY (NCT01445613)
- Testing
- RX Acculink Carotid Stent System (RX Acculink)
- Where
- United States
- Volunteers
- 1,203 people
- Sponsor
- Abbott Medical Devices
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