Clinical trials: Stroke, Cerebral
Parkinson's Disease, Stroke
Training With Exergame and Treadmill on Executive Function and Dual-task Performance
This study aimed to investigate the effects of dual-task training with exergame and treadmill on executive function and dual-task performance in individuals with PD and stroke and discuss the correlation between the change values…
- Trial name
- NCT03623841
- Testing
- Dual-task training, Treadmill training
- Where
- Taiwan
- Volunteers
- 28 people
- Sponsor
- National Yang Ming Chiao Tung University
Postoperative Delirium, Postoperative Stroke
Impact of Personalised Cardiac Anaesthesia and Cerebral Autoregulation on Neurological Outcomes in Patients Undergoing Cardiac Surgery
This international, multicentre prospective cohort study will assess whether perioperative duration and magnitude of mean arterial pressure (MAP) outside of an individual's cerebral autoregulation (CA) limits using near-infrared…
- Conditions
- Postoperative Delirium, Postoperative Stroke, Postoperative Cognitive Dysfunction
- Trial name
- PRECISION (NCT05595954)
- Testing
- Preoperative data collection, Intraoperative NIRS, Intraoperative TCD
- Where
- 4 sites in Switzerland, United Kingdom
- Volunteers
- 500 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Ischemic Stroke, Cerebral Infarction
Safely Quenching Complement in Stroke Survivors
This study will include adults (ages 18-80) who have had a stroke caused by a large blood clot blocking blood flow in the brain.
- Trial name
- SUCCESS (NCT07495722)
- Testing
- Pegcetacoplan Injection [Empaveli]
- Volunteers
- 20 people
- Sponsor
- Columbia University
Stroke, Peripheral Neuropathy
Arm Motor Control on Bi and Uni ADLs
This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs.
- Conditions
- Stroke, Peripheral Neuropathy, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- BiAs (NCT02778529)
- Testing
- Bilateral assessment robots (BiAS)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dysphagia, Aspiration
Effect of Afferent Oropharyngeal Pharmacological and Electrical Stimulation on Swallow Response and on Activation of Human Cortex in Stroke Patients With Oropharyngeal Dysphagia
Oropharyngeal dysphagia (OD) is a major complaint among many patients with stroke and causes severe complications. There is no specific treatment for these patients.
- Conditions
- Dysphagia, Aspiration, Stroke
- Trial name
- NCT01777672
- Testing
- Dietary and oral hygiene recommendations, oral TRPV1 agonist, pharyngeal electrical stimulation
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital de Mataró
Stroke, Cerebrovascular Accident
AMES Treatment of the Proximal Arm in Chronic Stroke
Subjects will receive 30 treatments with AMES, to the proximal arm which has been affected by a chronic stroke.
- Trial name
- AMES (NCT01934439)
- Testing
- 30 PAAD treatments
- Where
- United States
- Sponsor
- Oregon Health and Science University
Acute Ischemic Stroke
C-arm Cone Beam CTP Guided Cerebrovascular Interventions
The study objective for the Phase 2 of this research is to demonstrate and confirm the substantial time savings that can be obtained using cone beam computed tomography (CB-CT) for both complete image acquisition and rapid image…
- Trial name
- NCT05536895
- Testing
- C-Arm Cone Beam Computed Tomography, Multi-detector Computed Tomography
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Ischemic Stroke
Ischemic Stroke, Obesity and Thrombolysis
This study focuses on the relationship between obesity and stroke, which are both characterized by increasing incidence and prevalence with epidemic proportions worldwide and tremendous socio-economic consequences.
- Trial name
- ISOT (NCT04196894)
- Where
- 2 sites in Switzerland
- Volunteers
- 280 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ischemic Stroke, Anticoagulant Adverse Reaction
Evaluataion of NOAC Levels in Acute Stroke
Non-vitamin K antagonist oral anticoagulants (NOACs) are recommended over warfarin in preventing stroke and thromboembolism among patients with atrial fibrillation (AF) in several guidelines.
- Trial name
- NCT06144866
- Testing
- Dabigatran, rivaroxaban, apixaban, edoxaban
- Where
- Taiwan
- Volunteers
- 1,000 people
- Sponsor
- National Taiwan University Hospital
Cerebral Stroke, Stroke, Acute
Safety and Effectiveness of NXY-059 for the Treatment of Patients Who Have Suffered From a Stroke
This study will determine if NXY-059 will improve recovery from an acute stroke. The study is designed to look at both overall recovery and recovery of motor function, for example muscle strengthen and coordination.
- Conditions
- Cerebral Stroke, Stroke, Acute, Cerebrovascular Stroke, Ischemic Attack, Transient
- Trial name
- NCT00061022
- Testing
- NXY-059
- Where
- 256 sites in United States, Argentina and 28 more
- Volunteers
- 3,200 people
- Sponsor
- AstraZeneca
Acute Ischaemic Stroke
Perfluorocarbon (ABL-101) Oxygenation for Stroke: Trial With GOLD (Glasgow Oxygen Level Dependent Technology) Imaging Theranostic
This study evaluates the safety and tolerability of 3 dose levels of ABL-101 and supplemental oxygen in acute stroke patients.
- Trial name
- POST-IT (NCT03463551)
- Testing
- ABL-101, 0.9% NaCl
- Volunteers
- 18 people
- Sponsor
- NHS Greater Glasgow and Clyde
Hemianopia, Visual Field Defect Following Cerebrovascular Accident
Screening and Rehabilitation of Visual Field Defects in Post-Stroke Patients
In this study, the investigators will use a wearable device capable of performing this bedside assessment to evaluate the incidence of visual field loss in post-stroke patients.
- Trial name
- SCRiCaViPS (NCT07317739)
- Testing
- Early multisensory audio-visual stimulation training, Early visual field test
- Volunteers
- 300 people
- Sponsor
- Fondazione David Chiossone - Impresa Sociale
Ischemic Stroke, Acute
MRI Biomarkers of Effective Tissue Reperfusion After Thrombectomy of an Acute Proximal Occlusion of the Anterior Circulation
Cerebral infarction by proximal occlusion of the anterior circulation is common with major personal and societal consequences. MRI is the gold standard for exploring stroke, especially ischemic, and a number of biomarkers on…
- Trial name
- MR-Reperfusion (NCT04952077)
- Testing
- MRI
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Central Hospital, Nancy, France
Acute Ischemic Stroke
Heart Evaluation of Acute Ischemic Stroke With Reperfusion Therapy
Heart Evaluation of Acute ischemic stroke with Reperfusion Therapy (HEART) is a single-center observational registry evaluating the heart of patients hospitalized for acute ischemic stroke with reperfusion therapy.
- Trial name
- HEART (NCT06882577)
- Testing
- observational only- no intervention
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Soochow University
Stroke
Investigation of Factors Causing Knee Hyperextension During Walking in Chronic Stroke Patients
In this study, it is aimed to examine the factors that cause knee hyperextension in chronic stroke patients. Although the presence of weakness or spasticity in the quadriceps muscle, weakness or spasticity in the plantar flexors…
- Trial name
- NCT05513781
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Hacettepe University
Stroke
ExStroke Pilot Trial: Physical Exercise After Acute Ischaemic Stroke
Summary This study will look at physical exercise after acute ischaemic stroke. It is called the ExStroke Pilot Trial. Physical activity is associated with a lower risk of first-time stroke.
- Trial name
- NCT00132483
- Testing
- Instruction in physical training program
- Where
- Denmark
- Volunteers
- 314 people
- Sponsor
- Bispebjerg Hospital
Stroke
Tailored Hospital-based Risk Reduction to Impede Vascular Events After Stroke
The purpose of this study is to determine whether a culturally-sensitive multipronged post-discharge intervention can significantly reduce blood pressure, enhance achievement of guideline recommended targets for risk factor…
- Trial name
- THRIVES (NCT01900756)
- Testing
- THRIVES
- Where
- 3 sites in Nigeria
- Volunteers
- 400 people
- Sponsor
- Medical University of South Carolina
Stroke
Optimizing Parameters of Low-Intensity Focused Ultrasound for Cortical Modulation in Stroke Patients
The purpose of this research study is to find out the optimal intensity and frequency of Low Intensity Focused Ultrasound (LIFU) that is safe and tolerable in people who have had a stroke.
- Trial name
- LIFU (NCT05016531)
- Testing
- Low Intensity Focused Ultrasonic Stimulation, Low Intensity Focused Ultrasonic Stimulation Frequency
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Duke University
Stroke
Association of Vestibular and Postural Impairments With Functional Status in Stroke
: Stroke is leading cause of long-term disability in individuals. The location and extent of brain injury determines the severity of neurological deficits. The incidence of stroke dramatically increases in old age.
- Trial name
- NCT05139537
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Riphah International University
Aphasia
tDCS and Aphasia Treatment
This project will investigate the use of noninvasive brain stimulation in the form of tDCS (transcranial direct current stimulation) in conjunction with speech-language therapy, for the improvement of language production in…
- Trial name
- NCT01922245
- Testing
- Soterix 1x1 tDCS
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Hunter College of City University of New York
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