Clinical trials: Stroke, Cerebral
Stroke, Multiple Sclerosis
Design and Validation of Innovative Strategies Based on Dual-Task Approach
People affected by Stroke, Multiple Sclerosis (MS), and Parkinson's disease (PD) share severe and complex disabilities. Widespread neuro-inflammatory processes represent an important pathogenetic component in all three…
- Conditions
- Stroke, Multiple Sclerosis, Parkinson Disease, Dual Task Exercises
- Trial name
- START (NCT07254377)
- Testing
- Dual Task exercise, Physical therapy
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Brain Injuries, Traumatic Brain Injury
Diet Induced Ketosis for Brain Injury - A Feasibility Study
Each year, approx. 100 patients with severe brain injury is admitted to the Clinic for Neurorehabilitation/TBI Unit, Rigshospitalet.
- Conditions
- Brain Injuries, Traumatic Brain Injury, Subarachnoid Hemorrhage, Stroke
- Trial name
- NCT04308577
- Testing
- Ketogenic diet with added MCT
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Jens Rikardt Andersen
Idiopathic Toe Walking, Cerebral Palsy
The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in Children
Tight ankle muscles can produce ankle equinus (limited ability to pull the foot upward) and occur often in children, significantly impacting their ability to walk.
- Conditions
- Idiopathic Toe Walking, Cerebral Palsy, Hereditary Spastic Paraparesis, Traumatic Brain Injury
- Trial name
- Plantaris Sx (NCT07090057)
- Testing
- Tendoachilles (TA) lengthening or gastrocnemius (GN) recession, then Plantaris tenotomy, Plantaris tenotomy, then Tendoachilles (TA) lengthening or gastrocnemius (GN) recession
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Alberta
Ischemic Stroke
ERic Acute StrokE Recanalization (ERASER)
To monitor the effect of the ERIC® device in combination with SOFIA™ Distal Access Catheter on artery recanalization and on clinical outcomes in stroke patients using data from clinical routine application (ERASER).
- Trial name
- ERASER (NCT02534701)
- Testing
- ERIC® and SOFIA™
- Where
- 9 sites in Germany, Switzerland
- Volunteers
- 53 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine
Stroke
Treatment for Word Retrieval Impairments in Aphasia
In this study the investigators are examining the effectiveness of two different speech therapy protocols for word retrieval impairments experienced by individuals with stroke-induced aphasia.
- Trial name
- NCT00764400
- Testing
- Word Retrieval Treatments for Aphasia
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Old Dominion University
Stroke
Cognitive Motor Therapy Applications Using Videogame Platform
This study designs and develops an evidence-based game approach that will enhance the investigators understanding and usability of electronic tools to measure cognitive and sensorimotor abilities in an inpatient rehabilitation…
- Trial name
- NCT02256007
- Testing
- Paper and Pencil Assessments
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Cedars-Sinai Medical Center
ANCA-associated Primary Necrotizing Vasculitides
Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides
The purpose of this study is to assess whether rosuvastatin could reduce the subclinical markers of atherosclerosis and the incidence of major cardiovascular events in patients with primary necrotizing vasculitides.
- Trial name
- STATVAS (NCT02117453)
- Testing
- Rosuvastatin
- Where
- France
- Volunteers
- 121 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke, Motor Activity
Observational Study of Ischaemic Stroke
The rationale for this study is to facilitate future Phase II/III clinical trials and improve outcome for patients suffering residual disability after an ischaemic stroke.
- Trial name
- OSIS (NCT01859572)
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- ReNeuron Limited
Stroke, Acute, Stroke, Ischemic
Neuroimaging in Acute Stroke
The main aim of this study is to identify the predictive value of CT parameters (e-ASPECTS, CTP, collateral vessel status, volume, and location of ischemic lesion volume) at a 3-month functional outcome defined by the modified…
- Trial name
- e-Stroke (NCT05864495)
- Where
- Czechia
- Volunteers
- 500 people
- Sponsor
- University Hospital Ostrava
Atrial Fibrillation, T2DM (Type 2 Diabetes Mellitus)
RE-ELECT. Dabigatran vs Warfarin in AF Patients With T2DM and CKD
Kidney function in patients with atrial fibrillation (AF) is tending to decline over a time which is clearly demonstrated in clinical studies.
- Conditions
- Atrial Fibrillation, T2DM (Type 2 Diabetes Mellitus), Chronic Kidney Diseases
- Trial name
- RE-ELECT (NCT03789695)
- Testing
- Dabigatran Etexilate
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Irina Ermolaeva
Adverse Drug Reaction, Cinepazide
Post-Marketing Surveillance of the Cinepazide Maleate Injection: a Real World Study
Cinepazide Maleate Injection is widely used in cerebrovascular disease in china. The safety of the cinepazide, especially the blood system, has not been fully evaluated in Chinese population.
- Conditions
- Adverse Drug Reaction, Cinepazide, Stroke
- Trial name
- PACER (NCT01946919)
- Where
- 61 sites in China
- Volunteers
- 18,260 people
- Sponsor
- Peking University Third Hospital
Stroke, Parkinson Disease
Videofluoroscopic Swallowing Study (VFSS)
The study procedure of simultaneous VFSS and DDS measurement will be completed in one day and the subject will be followed within 2 business days after the study procedure to monitor for adverse events.
- Conditions
- Stroke, Parkinson Disease, Multiple Sclerosis, Oropharyngeal Dysphagia
- Trial name
- PORSCHE (NCT03387267)
- Testing
- Dysphagia Detection System
- Where
- 13 sites in United States, Finland
- Volunteers
- 452 people
- Sponsor
- Société des Produits Nestlé (SPN)
TIA, Ischemic Stroke
Sleep Disordered Breathing in Transient Ischemic Attack (TIA)/Ischemic Stroke and Continuous Positive Airway Pressure (CPAP) Treatment Efficacy
The study aims to observe the short term effect (3-month) of sleep disordered breathing (SDB) on cardiovascular parameters, heart rate variability, endothelial function and surrogate markers of atherosclerosis after acute…
- Trial name
- SAS-CARE (NCT01097967)
- Testing
- CPAP
- Where
- 5 sites in Germany, Italy and 1 more
- Volunteers
- 246 people
- Sponsor
- Prof. Claudio Bassetti
Stroke
EvolvRehab for Telerehabilitation
This study includes two stages to develop the use of EvolvRehab telerehabilitation in the use of Stroke patients, early after stroke. All tasks will be conducted by multiple research sites.
- Trial name
- NCT05875792
- Testing
- EvolvRehab - MoveWell
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Exeter
Stroke
Repetitive Transcranial Magnetic Stimulation (rTMS) to Promote Hand Recovery in Stroke
Paralysis following stroke stems not only from the loss of neurons killed by the stroke but also from the loss of neurons lying dormant in the stroke hemisphere.
- Trial name
- rTMS (NCT00913211)
- Testing
- rTMS, Motor learning training, rTMS and Tracking
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
Stroke, Acute, Angiography
Comparison Between TOF and SWAN Sequences in the Detection of Arterial Occlusion in Acute Ischemic Stroke Using MRI
Optimizing the MRI protocol in acute ischemic stroke remains a challenging issue. In this field, susceptibility-weighted sequences have proved their superiority over T2.
- Conditions
- Stroke, Acute, Angiography, Magnetic Resonance Imaging, Diagnosis
- Trial name
- TOF-SWAN (NCT03645902)
- Testing
- Magnetic resonance imaging
- Volunteers
- 34 people
- Sponsor
- Lille Catholic University
Chronic Stroke Patients
Combined Effect of Sensory Training With Bobath Therapy in Patients With Chronic Stroke
Chronic stroke causes moderate to severe impairments in proprioception, balance, and motor functions, which can impact upon an individual's ability to perform activities of daily living, leading to reduced quality of life and…
- Trial name
- NCT07139002
- Testing
- Bobath Therapy, Sensory Training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Stroke
Comparative Effects of Dual Task and PNF on Balance ,Cognition and Motor Function in Chronic Stroke Patients .
The aim of this study is to compare the effect of dual tasking and proprioceptive neuromuscular facilitation on balance, cognition and motor function in chronic stroke patients. It will be randomized clinical trial.
- Trial name
- NCT05931172
- Testing
- Dual tasking, PNF(proprioceptive neuromuscular facilitation exercises)
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Coronary Heart Disease and Stroke
A Comparison of the Estimates of Fuwai and Reynolds Risk Model
There are many risk prediction models. And their estimates are different. This study aimed to investigate the differences between the estimates of Fuwai and Reynolds risk model in Chinese, and investigate the reason for the…
- Trial name
- NCT02241239
- Where
- 2 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Wuhan Asia Heart Hospital
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