Clinical trials: Stroke Acute
Ischemic Stroke
Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke
The ARCHIMEDES study (Anti-inflammatory and anti-thRombotic therapy with colCHicine and low dose rIvaroxaban for Major adverse cardiovascular Events reDuction in ischEmic Stroke) will be a randomized, double-blind, 2x2 factorial…
- Trial name
- ARCHIMEDES (NCT06396858)
- Testing
- Rivaroxaban 2.5 Mg Oral Tablet, Colchicine 0.5 MG
- Volunteers
- 4,500 people
- Sponsor
- Brazilian Clinical Research Institute
Sarcopenia, Cerebral Stroke
Prevalence of Sarcopenia in Stroke Patients
The goal of this observational study is to analyze the characteristics of sarcopenia-related variables in post-acute and chronic stroke patients using various clinical measurement tools.
- Conditions
- Sarcopenia, Cerebral Stroke, Cerebral Vascular Accident (CVA)/Stroke
- Trial name
- NCT07492849
- Testing
- Objective assessments, Subjective assessment
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Cishan Hospital, Ministry of Health and Welfare
Large Vessel Occlusion, Stroke Acute
Rescue Stenting and Intravenous Thrombolysis In Patients With Large Vessel Ischemic Stroke
Intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) are the standard of care for treating selected patients with acute large-vessel occlusion stroke (LVOS).
- Conditions
- Large Vessel Occlusion, Stroke Acute, Thrombolysis, Rescue Stenting
- Trial name
- STARS (NCT06727006)
- Where
- 7 sites in Italy
- Volunteers
- 400 people
- Sponsor
- ASST Santi Paolo e Carlo
Acute Stroke
Remote Ischemic Conditioning Paired With Endovascular Treatment for Acute Ischemic Stroke
Ischemic stroke, which is due to the occlusion of a cerebral blood vessel, comprises nearly 80-90% of all strokes. Currently, reperfusion of the salvageable tissue via thrombolytic drug or endovascular treatment is the most…
- Trial name
- REVISE-2 (NCT03045055)
- Testing
- Remote ischemic conditioning., Endovascular treatment.
- Volunteers
- 180 people
- Sponsor
- Capital Medical University
Large Infarct Core, Post-stroke Lymphocytopenia
Methylprednisolone for Stroke With Large Infarct Core and Post-stroke Lymphocytopenia
The efficacy and safety of early adjunctive methylprednisolone therapy in acute ischemic stroke patients with large infarct cores (ASPECTS score < 6) and post-stroke lymphocytopenia remain unclear.
- Trial name
- MIRACLE-2 (NCT07202143)
- Testing
- Methylprednisolone sodium succinate, Normal Saline
- Where
- China
- Volunteers
- 200 people
- Sponsor
- YiLin
Acute Ischemic Stroke
Study of Compound Edaravone Injection for Treatment of Acute Ischemic Stroke
The primary objective of the study is to confirm the efficacy of compound Edaravone Injection via intravenous infusion every 12 hours in the patients with Acute Ischemic Stroke(AIS) in a double-blind, active-controlled manner.
- Trial name
- NCT02430350
- Testing
- Compound Edaravone Injection, Edaravone Injection
- Where
- 48 sites in China
- Volunteers
- 1,200 people
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Ischemic Stroke
Evidence-based Evaluation of TCM Key Syndrome Differentiation and Treatment for Acute Ischemic Stroke
The main purpose of this trial is to determine whether Chinese medicine (CM) for eliminating phlegm and clearing heat (EPACH) recipe continuously with nourishing Qi and activating blood circulation (NQABC) recipe, oral within 72…
- Trial name
- NCT04199455
- Testing
- Integrative Treatment (EPACH Recipe Granules + NQABC Recipe Granules)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Acute Ischemic Stroke
MRI-based Artificial Intelligence Software (NNS-SOT) for Onset Time Estimation in Lesion With Acute Ischemic Stroke
This study evaluates the efficacy of investigational device named Stroke Onset Time Artificial Intelligence(AI) (Model name:NNS-SOT).
- Trial name
- NCT06160726
- Where
- South Korea
- Volunteers
- 474 people
- Sponsor
- Nunaps Inc
Acute Hemorrhagic Stroke
Clinical Evaluation of the Combination of Symptoms and Symptoms With General Treatment for Acute Hemorrhagic Stroke
Objective To evaluate whether Xingnaojing injection combined with Naoxueshu oral liquid can significantly improve the clinical outcome of patients with intracerebral hemorrhage.
- Trial name
- NCT04946474
- Testing
- Xingnaojing injection + Shuxuetong oral liquid
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Peking University Third Hospital
Acute Ischemic Stroke
Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke
The primary objective of the study is to assess the clinical effects of natalizumab versus placebo in acute ischemic stroke on clinical measures of functional independence and activities of daily living.
- Trial name
- ACTION2 (NCT02730455)
- Testing
- natalizumab
- Where
- 53 sites in United States, Germany and 2 more
- Volunteers
- 277 people
- Sponsor
- Biogen
Shock, Acute Respiratory Distress Syndrome
Correlation Between EIT-based Pulse Wave Method for Pulmonary Perfusion Monitoring and Pulmonary Artery Catheter-based Stroke Volume Measurement
The goal of this clinical study is to learn if a new, non-invasive monitoring method called EIT Pulse Wave can accurately measure blood flow to the lungs (pulmonary perfusion) and predict heart stroke volume (SV) in critically…
- Trial name
- EIT-Cath Corre (NCT07385963)
- Testing
- Synchronous Data Acquisition of EIT and Pulmonary Artery Catheter
- Where
- China
- Volunteers
- 19 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Stroke
1-year Clinical Outcomes in Recombinant Tissue Plasminogen Activator (Rt-PA) Treated Chinese Acute Ischaemic Stroke (AIS) Patients
The objective of the study is to find out the 1-year clinical outcomes among Acute Ischaemic Stroke (AIS) patients who were treated with intravenous (IV) Recombinant Tissue Plasminogen Activator (rt-PA) within 4.5 hours of…
- Trial name
- NCT05395338
- Testing
- rt-PA
- Where
- China
- Volunteers
- 12,551 people
- Sponsor
- Boehringer Ingelheim
Ischemic Stroke
Clinical Trial to Assess the Efficacy and to Evaluate Safety of HT047 in Patients With Acute Ischemic Stroke
To assess the efficacy and to evaluate safety of HT047 in patients with acute ischemic stroke
- Trial name
- NCT02828540
- Testing
- HT047 High-dose group, HT047 Low-dose group
- Where
- 8 sites in South Korea
- Volunteers
- 78 people
- Sponsor
- Hocheol Kim
Stroke
Stroke Team Remote Evaluation Using a Digital Observation Camera
The purpose of this trial is to determine if an experimental remote video camera system is an effective way for a stroke specialist to evaluate stroke patients from a distant site.
- Trial name
- STRokE DOC (NCT00283868)
- Where
- 4 sites in United States
- Volunteers
- 234 people
- Sponsor
- University of California, San Diego
Fall Due to Loss of Equilibrium, Acute Stroke
Turkish Version of Ottawa Sitting Scale in Patients With Stroke
The aim of the study is to describe the cultural adaptation of the Ottawa Sitting Scale and to examine the factor structure, reliability and validity of the scale in patients with stroke.
- Conditions
- Fall Due to Loss of Equilibrium, Acute Stroke, Balance; Distorted, Fear
- Trial name
- NCT04752878
- Testing
- Ottawa sitting scale
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gulhane School of Medicine
Prevention of Thromboembolic Events, Atrial Fibrillation
A Study to Learn How the Study Treatment Asundexian Moves Into, Through and Out of the Body, How it Works, How Safe it is, and How it Affects the Body in Participants With Mild or Moderate Reduction of Liver Function Compared to Participants With Normal Liver Function
Researchers are looking for a better way to prevent the formation of blood clots in people who have or have had: an irregular and often rapid heartbeat a blocked blood flow to the heart a blocked or reduced blood flow to a part…
- Conditions
- Prevention of Thromboembolic Events, Atrial Fibrillation, Acute Myocardial Infarction, Non-cardioembolic Ischemic Stroke
- Trial name
- NCT05419635
- Testing
- Asundexian (BAY2433334)
- Where
- Germany
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Bayer
Dehydration, Ischemic Stroke
BUN/Cr-based Hydration Therapy to Improve Outcome of Patients With Acute Ischemic Stroke
English Synopsis I. Title of Study: A trial of BUN/Cr-based hydration therapy to reduce stroke-in-evolution and improve short-term functional outcomes for dehydrated patients with acute ischemic stroke-version 2. II.
- Trial name
- NCT05121389
- Testing
- normal saline
- Where
- Taiwan
- Volunteers
- 288 people
- Sponsor
- Chang Gung Memorial Hospital
Intracranial Aneurysm, Cerebral Aneurysm
Safety and Clinical Effectiveness of Pipeline™ Shield Devices for Intracranial Aneurysms
This observational, retrospective, single-arm, multi-centre cohort study will use real-world data (RWD) to develop real-world evidence (RWE) of the safety and clinical effectiveness of the Pipeline™ Flex Embolization Device with…
- Conditions
- Intracranial Aneurysm, Cerebral Aneurysm, Subarachnoid Hemorrhage, Stroke, Acute
- Trial name
- SCOPE-AUS (NCT03815149)
- Testing
- Pipeline™ Flex Embolization Device with Shield Technology™
- Where
- 4 sites in Australia
- Volunteers
- 500 people
- Sponsor
- Gold Coast Hospital and Health Service
Aphasia
Study of Modified Constraint-Induced Aphasia Therapy Schedule to Treat Patients Following Sub-acute Stroke
The purpose of this study is to assess the feasibility of modified Constraint-Induced Aphasia Therapy (CIAT) in the early sub-acute stage and to examine the efficacy of modified CIAT versus standard treatment with the same…
- Trial name
- MCIAT (NCT01625676)
- Testing
- Investigate efficacy of modified ciat schedule, examine the efficacy of standard treatment versus modified ciat schedule
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- NRZ Magdeburg Median Kliniken GmbH & Co
Acute Ischemic Stroke
Impact of a Standardized Alarming System on Treatment Times and Workflow in Stroke Patients With Interhospital Transfer for Thrombectomy
The aim of this study is to evaluate the impact of a standardized alarming system on treatment times and workflow in stroke patients with interhospital transfer for mechanical thrombectomy (MT).
- Trial name
- NCT05963685
- Testing
- standardized MT alarming system
- Where
- Germany
- Volunteers
- 280 people
- Sponsor
- Munich Municipal Hospital