Clinical trials: Stroke Assessment
Stroke, Chronic Stroke
Virtual Physical Activity Seated Exercise - Phase 2
This study will determine the acceptability of delivering seated exercises online and if seated exercises can improve balance, mobility, quality of life, and cardiometabolic health in those living with a stroke related mobility…
- Conditions
- Stroke, Chronic Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- V-PASE (NCT05724823)
- Testing
- Virtual Physical Activity Seated Exercises (V-PASE)
- Where
- 5 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Post Stroke Upper Limb Spasticity
A Single Center, Phase I Clinical Trial to Evaluate the Safety of LIZTOX Inj in the Treatment of Post Stroke Upper Limb Spasticity
Investigational Product: LIZTOX inj 100unit(HU-014) Title : A Single Center, Phase I Clinical Trial to Evaluate the Safety of LIZTOX Inj in the Treatment of Post Stroke Upper Limb Spasticity Sites and investigators : Asan Medical…
- Trial name
- NCT04415346
- Testing
- HU-014 Inj
- Where
- South Korea
- Volunteers
- 13 people
- Sponsor
- Huons Co., Ltd.
Self Rehabilitation Combined With BTI on Upper Limb
Upper Limb Botulinum Toxin Injection Combined With Self Rehabilitation
To show that the addition of a self-rehabilitation program to standard treatment, involving repeated BTI and usual physiotherapy, improves impairment and activity limitation of the paretic upper limb more than the control…
- Trial name
- Armautotox (NCT02699762)
- Testing
- self rehabilitation of upper limb in experimental group
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Arterial Ischemic Stroke
A Proof of Concept Study to Evaluate the Safety of Afamelanotide in Patients With Acute Arterial Ischaemic Stroke (AIS)
The primary study objective is to assess the safety of afamelanotide while the secondary objective is to assess whether the therapy affects the size of the penumbra, by increasing blood flow, restoring oxygen supply to the brain…
- Trial name
- NCT04962503
- Testing
- Afamelanotide
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Acute Ischemic Stroke
Construction and Evaluation of an Intelligent Decision System for Reperfusion Therapy in Acute Ischemic Stroke
This multicenter, cluster-randomized controlled trial will evaluate the effectiveness and safety of the LingBao System, an AI-enabled clinical decision support platform for reperfusion therapy in acute ischemic stroke (AIS).
- Trial name
- NCT07316049
- Testing
- LingBao System, Standard Care
- Volunteers
- 3,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke Assessment, National Institutes of Health Stroke Scale
Effect of E-learning Training on National Institutes of Health Stroke Scale (NIHSS) and Modified Rankin Scale (mRS) Assessment
The goal of this web-based randomized clinical trial is to evaluate whether an e-learning training program improves the accuracy of National Institutes of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS) assessments…
- Conditions
- Stroke Assessment, National Institutes of Health Stroke Scale, Modified Rankin Scale, Clinical Competence
- Trial name
- NCT07318376
- Testing
- Educational intervention
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Stuby Loric
Stroke, Stroke Acute
Individual vs Co-Treatment in Acute Stroke Rehabilitation and Evaluation
This is a single center, pragmatic, randomized trial comparing the effectiveness of two commonly used approaches (co-treatment and individual treatment) in acute care rehabilitation.
- Trial name
- ICARE (NCT07411534)
- Testing
- Co-treatment, Individual Treatment
- Where
- United States
- Volunteers
- 567 people
- Sponsor
- Vanderbilt University Medical Center
Coronary Artery Disease, Stroke
The SMART-ORACLE Study
After having had a first cardiovascular event, there is a considerable risk of developing a subsequent event. Only recently, a risk prediction model was developed for this group of patients.
- Conditions
- Coronary Artery Disease, Stroke, Peripheral Arterial Disease, Hypertension
- Trial name
- SMART-ORACLE (NCT01932671)
- Where
- Netherlands
- Volunteers
- 1,500 people
- Sponsor
- UMC Utrecht
Carotid Artery Stenosis, Atherosclerosis
Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis
The aim of this study is to determine whether optimal medical treatment can postpone carotid endarterectomy.
- Conditions
- Carotid Artery Stenosis, Atherosclerosis, Stroke
- Trial name
- AMTEC (NCT00805311)
- Testing
- Carotid Endarterectomy, atorvastatin, aspirin, losartan, amlodipine
- Where
- 2 sites in Russia
- Volunteers
- 400 people
- Sponsor
- Russian Cardiology Research and Production Center
Stroke, Upper Limb Hypertonia
An Algorithm for Prognosis of Upper Limb Paresis in Patients With Subacute Stroke
Aim study 1:Assess the accuracy of PREP2 when applied in a subacute rehabilitation setting. Aim study 2: Prediction of real life UL use. Method: A prospective cohort study.
- Conditions
- Stroke, Upper Limb Hypertonia, Physical Activity
- Trial name
- NCT03632499
- Testing
- rehabilitation
- Where
- Denmark
- Volunteers
- 103 people
- Sponsor
- University of Aarhus
Stroke
OASIS STUDY Outcome Assessment Using SF-36 v2 in Stroke Patient Study(OASIS STUDY)
1. To survey the health-related quality of life using the SF-36v2 score of patients with chronic brain infarction in Japan 2. Chronic brain infarction in Japan is better than EU/USA
- Trial name
- NCT00281034
- Where
- Japan
- Volunteers
- 2,069 people
- Sponsor
- Kyorin Pharmaceutical Co.,Ltd
Ischemic Stroke, Thrombectomy
IMMunological resPonse Assessment afteR Acute iSchemic Stroke Treated With Endovascular Therapy (IMPRESS)
IMPRESS study aims to describe the immuno-inflammatory and thrombo-inflammatory profiles during the first 24/36 hours of treatment of patients suffering from AIC treated with TM, and to study the possible impact of these profiles…
- Trial name
- IMPRESS (NCT04663399)
- Testing
- Prospective patient
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Ischemic Stroke, Atrial Fibrillation
Lixiana Acute Stroke Evaluation Registry
Study Design: Lixiana Acute Stroke Evaluation Registry (LASER) is a randomized controlled trial with an associated registry. Patients with previously known or newly diagnosed atrial fibrillation (AF) and acute ischemic stroke…
- Conditions
- Ischemic Stroke, Atrial Fibrillation, Hemorrhagic Transformation Stroke
- Trial name
- LASER (NCT03494530)
- Testing
- Edoxaban 60 MG, Edoxaban 30 mg
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Alberta
Heart Attack, Cardiac Arrest
Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys
Based on limited published epidemiological data, up to an alarming 1 in 50 surgical inpatients die within 30 postoperative days.
- Conditions
- Heart Attack, Cardiac Arrest, Congestive Heart Failure, Atrial Fibrillation
- Trial name
- SATISFY-SOS (NCT02032030)
- Where
- United States
- Volunteers
- 73,952 people
- Sponsor
- Washington University School of Medicine
Post Stroke
Rehabilitation Based on Hybrid Neuroprosthesis
The study is a pilot, multi-center, prospective, and open study to test feasibility, functionality and usability of a device defined as a hybrid neuroprosthesis.
- Trial name
- ReHyb (NCT07270484)
- Testing
- ReHyb-HPP, ReHyb-LPP
- Where
- 2 sites in Germany, Italy
- Volunteers
- 24 people
- Sponsor
- Villa Beretta Rehabilitation Center
Acute Ischemic Stroke, Ischemic Stroke
Clinical Trial to Evaluate the Safety of Continuous IV Tirofiban in Acute Ischemic Stroke
We will recruit men and non-pregnant women of any ethnic background between the age ≥ 18 and ≤ 90 years that have acute ischemic stroke and underwent Mechanical Thrombectomy (MT) with TICI 2b or 2b following MT.
- Trial name
- iTREMT (NCT04818944)
- Testing
- Tirofiban Hydrochloride
- Where
- United States
- Sponsor
- University of Iowa
Ischemic Stroke, Blood Pressure
Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Stroke Patients
Elevated blood pressure (BP) consists of a major public health concern especially in low and middle income countries. Besides being a highly prevalent condition, it is also a risk factor for several major cardiovascular events…
- Conditions
- Ischemic Stroke, Blood Pressure, Cognitive Impairment, Vascular Diseases
- Trial name
- OPTIMAL Stroke (NCT04036409)
- Testing
- Intensive Control of Systolic Blood Pressure (SBP), Standard control of Systolic Blood Pressure (SBP)
- Where
- 30 sites in Brazil
- Volunteers
- 4,368 people
- Sponsor
- Hospital Israelita Albert Einstein
Stroke
Robot-Assisted Rehabilitation in Individuals With Stroke
Stroke has a high rate of morbidity and mortality worldwide. This disease is the third leading cause of death after ischemic heart disease and cancer. Stroke is also the leading cause of disability in adults.
- Trial name
- NCT05550311
- Testing
- Robot-assisted rehabilitation, Conventional rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biruni University
Family Caregivers, Stroke
Telehealth Assessment and Skill-Building Intervention for Stroke Caregivers (TASK III)
Caring for a family member after a stroke can be very difficult and worsen the physical and mental health of untrained caregivers.
- Trial name
- NCT05304078
- Testing
- Telehealth Assessment and Skill-Building Kit (TASK III) Group, Information Support and Referral (ISR) Group
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Acute Ischemic Stroke, Cerebral Stroke
Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke
Extensive research is being conducted in search of neuroprotective agents for possible use in the acute phase of stroke and agents that can be used for neurorepair in later stages of stroke.
- Trial name
- RESPECT-ETB (NCT05691244)
- Testing
- Drug: Normal Saline, Sovateltide
- Where
- 54 sites in United States, Germany and 2 more
- Volunteers
- 514 people
- Sponsor
- Pharmazz, Inc.
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