Clinical trials: Stroke Assessment
Ischemic Stroke
Augmenting Cerebral Blood Flow to Preserve the Penumbra Trial
The primary objective of the study is to demonstrate that SPG (Sphenopalatine Ganglion) stimulation started within 6 hours from stroke onset slows the expansion of the infarct core volume in acute ischemic stroke.
- Trial name
- ImpACT-P (NCT04014621)
- Testing
- SPG stimulation
- Where
- 4 sites in Georgia
- Volunteers
- 100 people
- Sponsor
- BrainsGate
Cerebral Infarction
Chinese Assessment for Vinpocetine In Neurology
Trial Title：The treatment of Vinpocetine（Cavinton）in patients with cerebral infarction, an open, randomized, multi-center control study 1.
- Trial name
- CAVIN (NCT01400035)
- Where
- China
- Volunteers
- 610 people
- Sponsor
- Shanghai Rxmidas Pharmaceuticals Co. Ltd.
Stroke
Follow-up of Patients' Physical Activity in Post-hospitalization
Physical exercise has been identified as a major item of many affecting many chronic diseases and stroke rehabilitation. It contributes to an improvement in the quality of life and to a decrease in the current treatment…
- Trial name
- TICAA'DOM (NCT01822938)
- Testing
- incentive program for physical activity
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Limoges
Ischemic Stroke
Systematic Evaluation of Patients Treated With Stroke Devices for Acute Ischemic Stroke (STRATIS) Registry
The purpose of this registry is to assess clinical outcomes, and different factors that may affect these clinical outcomes such as systems of care, associated with the use of Covidien market-released neurothrombectomy devices…
- Trial name
- NCT02239640
- Where
- 55 sites in United States
- Volunteers
- 984 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Heart Failure, Atrial Fibrillation
Left Atrial Distensibility to Predict Prognosis in Consecutive Patients
Left ventricular filling pressure (LVFP) has prognostic significance in patients with heart failure. Traditionally, it should be assessed by invasive method, as cardiac catheterization and Swan-Gung catheter.
- Conditions
- Heart Failure, Atrial Fibrillation, Stroke
- Trial name
- NCT01171040
- Testing
- Echocardiography, including the measurements of left atrial (LA) distensibility
- Where
- Taiwan
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Stroke, Gait, Hemiplegic
Validity of a Belt Mounted Accelerometer to Assess Walking Measures in Patients With Chronic Stroke
The aim of this study is to validate the G-walk for several gait parameters, tested against a gold standard three dimensional camera system.
- Trial name
- NCT04288960
- Testing
- Gwalk accelerometer walking trials
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Winchester
Stroke
Impact of Verticalization on Intracranial Hemodynamics Assessed in Transcranial Doppler at the Acute Phase of Cerebral Infarction
The management of patients with ischemic stroke or transient ischemic attack is based on the preservation of a brain area by maintaining sufficient intracranial hemodynamics (IH) and with rapid recanalization.
- Trial name
- STAND (NCT03985059)
- Testing
- Transcranial Doppler
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Aphasia, Communication
Communication Book in Pragmatic Communication in Vascular Aphasics
This study aims to evaluate, in communication tasks, the pragmatic effectiveness of the communication book in the general conditions of use and its maintenance in the implementation of the compensatory strategies of communication…
- Trial name
- APHACOM (NCT04070625)
- Testing
- Communication book group, Control group
- Volunteers
- 34 people
- Sponsor
- University Hospital, Bordeaux
Stroke, Genetic Association Studies
Genetic Variants in Stroke
Stroke is the leading cause of death and disability in Brazil and worldwide, with a significant socioeconomic impact. Despite advances in prevention and treatment, the role of genetic variants in ischemic stroke remains…
- Trial name
- ÁRTEMIS-Brasil (NCT07186517)
- Where
- 11 sites in Brazil
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hospital Moinhos de Vento
Stroke
Goal-setting in Stroke: From Guideline Towards Implementation: a Realist Evaluation
Overall objective: The aim of the project is to integrate the quality improvement programme on goal setting into the current care of people with stroke and to test and refine this programme. Target group: 1.
- Trial name
- NCT06065397
- Testing
- Goal setting improvement program
- Where
- Belgium
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Aortic Stenosis
Femoral vs Radial Approach and MRI Evaluation of Strokes
Symptomatic cerebral infarction following cardiac catheterization is rare but silent brain injury could occur at an unexpectedly high rate.
- Trial name
- NCT00329979
- Testing
- vascular access site
- Where
- France
- Volunteers
- 152 people
- Sponsor
- University Hospital, Caen
Acquired Brain Injury, Stroke
A Blended Psychological Intervention for Depression After Acquired Brain Injury
1.3 million people in the UK live with an Acquired Brain Injury (ABI) as a result of experiencing a stroke or traumatic brain injury (TBI). Up to 50% of individuals with ABI will experience depression.
- Conditions
- Acquired Brain Injury, Stroke, Head Injury
- Trial name
- NCT05788146
- Testing
- Cognitive Behavioural Therapy
- Volunteers
- 20 people
- Sponsor
- King's College London
Ventricular Dysfunction, Left, Ventricular Function, Left
Federated Learning for Point-of-Care Cardiac Ultrasound
This prospective, multicenter study will evaluate a federated machine-learning system designed to analyze focused cardiac point-of-care ultrasound examinations.
- Conditions
- Ventricular Dysfunction, Left, Ventricular Function, Left, Echocardiography, Ultrasonography
- Trial name
- FL-POCUS (NCT07800962)
- Testing
- Focused Cardiac Point-of-Care Ultrasonography, FL-POCUS Federated Machine-Learning Analysis System
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Truway Health, Inc.
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Atrial Fibrillation, Stroke
Galectin-3 for Thromboembolic Formation in Patients With Atrial Fibrillation CHA₂DS₂-VASc Scoring
Atrial Fibrillation is considered as one of a common cardiac arrhythmia that presented with rapid and irregular rhythm and has an increased incidence.There are different types of atrial fibrillation one of these is paroxysmal…
- Trial name
- NCT03413072
- Volunteers
- 140 people
- Sponsor
- Assiut University
Cerebrovascular Accident, Paralysis
Motor Recovery in Recent Stroke Patients Treated With Amphetamine and Physical Therapy
The purpose of this study is to determine if giving amphetamines along with standard rehabilitation speeds motor recovery after a stroke.
- Trial name
- NCT00001783
- Testing
- 0-15 Water
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Cerebrovascular Accident
Cardiac Rehabilitation of Stroke Survivors (SRP-CROSS)
This study examines the effectiveness of the cardiac rehabilitation program for stroke patients. The study will examine if patients with stroke, who receive cardiac rehabilitation in addition to their standard of care treatments…
- Trial name
- SRP-CROSS (NCT05651945)
- Testing
- Cardiac rehabilitation program
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Hackensack Meridian Health
Coronary Disease, Coronary Artery Bypass
Integrated Assessment of Cervicocerebral Vessels to Improve the Brain Injury for CAGB Patients (IACV Study)
The goal of this study is to establish a prospective study to focus on the high-risk stroke population who require coronary artery bypass graft surgery.
- Conditions
- Coronary Disease, Coronary Artery Bypass, Strokes Thrombotic
- Trial name
- NCT06275139
- Testing
- Integrated Assessment of Cervicocerebral Vessels
- Where
- China
- Volunteers
- 348 people
- Sponsor
- China National Center for Cardiovascular Diseases
Neurological Diseases or Conditions, Fluid Responsiveness
A Gray Zone Approach to Stroke Volume Variation Derived From NICOM
Optimal fluid management has been considered as crucial part to determine postoperative outcome and organ function. Recently developed, non invasive cardiac output measurement(NICOM, Cheetah Medical, Portland, OR)has enabled…
- Conditions
- Neurological Diseases or Conditions, Fluid Responsiveness, Non Invasive Cardiac Output Monitoring, Gray Zone
- Trial name
- NCT01898975
- Testing
- 500ml fluid loading
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Stroke
Single and Repeat Doses of DMT in Healthy Subjects
This study aims to assess the safety and tolerability of single ascending, and fixed repeated doses of N,N-Dimethyltryptamine (DMT) in healthy subjects, when given by intravenous (IV) infusion.
- Trial name
- NCT05559931
- Testing
- N,N-Dimethyltryptamine
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Algernon Pharmaceuticals
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