Clinical trials: Stroke Assessment
Upper Limb Spasticity After Stroke
A Prospective, Non-interventional Survey to Evaluate Injection Intervals and Treatment Modalities of Botulinum Toxin A (BoNT-A) in Adult Patients Suffering From Upper Limb Spasticity After Stroke
The purpose of the protocol is to evaluate injection intervals and treatment modalities up to 3 years follow-up of botulinum toxin A (BoNT-A) in adult patients suffering from upper limb spasticity after stroke.
- Trial name
- DECIDE (NCT01239628)
- Where
- 11 sites in Belgium
- Volunteers
- 45 people
- Sponsor
- Ipsen
Ischemic Cerebrovascular Disease, Acute Ischemic Stroke
Efficacy and Safety of Calculus Bovis Sativus (CBS) for Ischemic Cerebral Vascular Disease (CBSinICVD)
The most common cause of death for Chinese patients is ischemic cerebrovascular diseases(ICVD), particularly cerebral infarction.
- Conditions
- Ischemic Cerebrovascular Disease, Acute Ischemic Stroke, Cerebral Small Vessel Diseases
- Trial name
- NCT06474507
- Testing
- Calculus bovis sativus (CBS)
- Where
- 2 sites in China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Stroke, Ischemic
Testing a New Treatment Strategy to Improve Secondary Stroke Prevention for Older Adults: The STROKE75+ Trial
The overall aim of this research is to improve secondary stroke prevention for older patients with stroke. In current practice, patients with stroke are often prescribed antiplatelet therapy with either aspirin or clopidogrel to…
- Trial name
- STROKE75+ (NCT07454707)
- Testing
- Edoxaban 15 mg, Aspirin or clopidogrel
- Where
- Canada
- Volunteers
- 1,204 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke
Telehealth Intervention Involving HEARTS Technical Package and Activity Monitor to Promote Physical Activity Post-stroke
Objectives: The aim of this feasibility randomized controlled trial (RCT) study is to investigate whether the theoretically informed telehealth intervention involving the HEARTS Technical Package and the use of an activity…
- Trial name
- NCT06068036
- Testing
- Telehealth intervention: HEARTS technical package + activity monitor (Smartwatch Mi Band 7®), Telehealth intervention: HEARTS technical package
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Federal University of Minas Gerais
Cerebrovascular Stroke
Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke
The purpose of this study is to examine how different areas in the brain interact with each other and how using brain imaging and brain stimulation approaches can influence these interactions.
- Trial name
- NCT02465034
- Testing
- Transcranial Magnetic Stimulation, Traditional Paired Associative Stimulation, Median Nerve Stimulation
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Emory University
Stroke, Sleep Apnea
Impact of Early Ventilation in Stroke Outcomes in Patients With Sleep Apnea After First Ever Stroke
To evaluate the impact of early ventilation in stroke outcomes in patients with sleep apnea and first ever stroke, 1 month after stroke.
- Trial name
- NCT04903951
- Testing
- Adaptive Servoventilation (ASV) therapy, Best medical treatment
- Where
- Portugal
- Volunteers
- 90 people
- Sponsor
- Philips Portuguesa S.A.
Stroke, Post Stroke
An Ecological Momentary Assessment Based Program to Support Self-Management for Post-stroke Patients
The goal of this feasibility study is to test whether a new approach that combines real-time symptom tracking (Ecological Momentary Assessment) with machine learning can help people recovering from a stroke to better manage…
- Trial name
- NCT07691411
- Testing
- Ecological Momentary Assessment based Self-management Program
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Hypertension
CEEEC-II: A 12-Week Physical and Cognitive Enrichment Extension Study in Older Stroke Survivors With Multimorbidity
CEEEC-II is a 12-week, community-based, prospective extension study conducted in 32 community health service stations in Kunshan, China.
- Conditions
- Stroke, Hypertension, Type 2 Diabetes Mellitus (T2DM), Multimorbidity
- Trial name
- CEEEC-II (NCT07778771)
- Testing
- Physical Enrichment, Cognitive Enrichment
- Where
- China
- Volunteers
- 365 people
- Sponsor
- Duke Kunshan University
Stroke, Ischemic
A Phase Ⅱb Study of XY03-EA Tablets in Acute Ischemic Stroke
This was a multicenter, randomized, double-blind, placebo-controlled, parallel-group Phase Ⅱb/Ⅲ clinical study to evaluate the efficacy and safety of XY03-EA tablets, a novel oral neuroprotective agent, and explore the…
- Trial name
- XY03-EA (NCT06755944)
- Testing
- XY03-EA 150 mg (per dose), XY03-EA 300 mg (Regimen A), XY03-EA 300 mg (Regimen B)
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Shijiazhuang Yiling Pharmaceutical Co. Ltd
Post-stroke Disorders
"Cognitive, Motor and Sleep Evaluation in Patients With Ischemic Stroke of Basal Ganglia After Thrombectomy"
The goal of this interventional study is to learn about the clinical outcomes of acute ischemic stroke treated with mechanical thrombectomy resulting in a selective ischemia of the basal ganglia.
- Trial name
- CMS - SBGT (NCT05878002)
- Testing
- polysomnography
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stroke, Cardiovascular Diseases
Kinesio Taping in Stroke Patient
Despite being nearly independent in daily life, chronic high-functioning stroke survivors still experienced mild impairments in skilled hand function.
- Conditions
- Stroke, Cardiovascular Diseases, Physical Disability
- Trial name
- Kinesio taping (NCT06188845)
- Testing
- Kinesio taping
- Where
- Taiwan
- Volunteers
- 17 people
- Sponsor
- Taiwan Municipal An-Nan Hospital-China Medical University
Stroke
Effects of Multi-direction Stepping and Weight Shifting Exercises in Stroke Patients
Stoke is a leading cause of disability that results not only in persistent neurological deficits but also profound physical de-conditioning that propagates stroke-related secondary disability.
- Trial name
- NCT05285241
- Testing
- Multidirectional stepping exercises, Conventional physiotherapy group
- Where
- Saudi Arabia
- Volunteers
- 24 people
- Sponsor
- King Saud University
Dysphagia Following Cerebral Infarction, Dysphagia Following Nontraumatic Intracerebral Hemorrhage
Validation and Reliability Testing of Dysphagia Trained Nurse Assessment
Nurses at Royal Derby Hospital, UK have been trained to use a comprehensive protocol based dysphagia assessment (Dysphagia Trained Nurse Assessment (DTNAx)) to assess all acute stroke patients on admission.
- Trial name
- NCT03700853
- Testing
- Dysphagia Trained Nurse Assessment (DTNAx)
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- University of Nottingham
Cardiovascular Risk Factors, Metabolic Syndrome
Cardiovascular Risk Factors in an Ambulatory Urban Patient Population
According to WHO estimations, cardiovascular diseases (CVDs) are the number one cause of death globally. More people die annually from CVDs than from any other cause.
- Conditions
- Cardiovascular Risk Factors, Metabolic Syndrome, Lifestyle Modification, Coronary Artery Disease
- Trial name
- AsuRiesgo (NCT00486993)
- Testing
- Dietary and nutritional modification, Stop smoking, Regular physical activities
- Where
- Paraguay
- Volunteers
- 18,287 people
- Sponsor
- Heidelberg University
Stroke, Traumatic Brain Injury
Validation of an Obstacle Course Used in Patients With Muscle Tightness
This study is being conducted to compare healthy patients versus patients with muscle tightness in their leg(s) after an acquired brain injury using walking trials time, a balance test, and foot pressure data.
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity
- Trial name
- NCT00776048
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Ischemia Stroke, Electro-acupuncture
Electroacupuncture-Induced Changes in Tongue Features in Early Stroke Patients Using ZMT-1A Imaging System
This prospective clinical study aims to evaluate changes in tongue characteristics before and after a four-week course of electroacupuncture in patients undergoing early rehabilitation following ischemic stroke.
- Trial name
- ZMT-StrokeEA (NCT07107958)
- Testing
- Electroacupuncture
- Where
- 3 sites in Vietnam
- Volunteers
- 200 people
- Sponsor
- Dr Nguyen Ngo Le Minh Anh MD, PhD
Stroke
Follow-up of Patients' Physical Activity in Post-hospitalization
Physical exercise has been identified as a major item of many affecting many chronic diseases and stroke rehabilitation. It contributes to an improvement in the quality of life and to a decrease in the current treatment…
- Trial name
- TICAA'DOM (NCT01822938)
- Testing
- incentive program for physical activity
- Where
- France
- Volunteers
- 84 people
- Sponsor
- University Hospital, Limoges
Disorder of Consciousness, Paralysis
Awareness Detection and Communication in Disorders of Consciousness
STUDY OVERVIEW Brain injury can result in a loss of consciousness or awareness, to varying degrees. Some injuries are mild and cause relatively minor changes in consciousness.
- Conditions
- Disorder of Consciousness, Paralysis, Motor Neuron Disease, Stroke
- Trial name
- NCT03827187
- Testing
- Motor imagery based EEG-BCI
- Where
- 18 sites in Ireland, United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Ulster
Stroke
The Assessment of Knee Joints Function in People After Stroke
The study aims to assess the function of knee joints in patients after stroke compared to healthy people and evaluate the impact of rehabilitation on the function of knee joints in people after stroke.
- Trial name
- NCT06746493
- Testing
- Rehabilitation
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Stroke
Argatroban Plus R-tPA for Acute Ischemic Stroke
Acute ischemic stroke (AIS) is the most common type of stroke, which has high rate of morbidity, mortality and disability. A large number of studies have confirmed that the thrombolytic therapy can effectively open blood vessels…
- Trial name
- NCT03740958
- Testing
- rt-PA, Argatroban
- Where
- China
- Volunteers
- 808 people
- Sponsor
- General Hospital of Shenyang Military Region
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