Clinical trials: Stroke Assessment
Chronic Subdural Hematoma, Anticoagulant-induced Bleeding
Management of Anticoagulants and Antithrombotics in Patients With CSDH
Primary objective of the study will be to compare, up to 6 months after surgery, number of relapses (post operative re-bleeding) or intracerebral hemorrhage (others than subdural hematomas) and thromboembolic or cardiovascular…
- Conditions
- Chronic Subdural Hematoma, Anticoagulant-induced Bleeding, Thromboembolic Stroke, Cardiovascular Stroke
- Trial name
- THERCA (NCT05079295)
- Testing
- CSDH evacuation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University Hospital of Ferrara
Mitochondrial Diseases, Maternally Inherited Diabetes and Deafness (MIDD)
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
The KHENERFIN study aims to determine whether the study medicine, sonlicromanol, is able to reduce symptoms of fatigue and the impact of fatigue on daily life, and whether sonlicromanol is able to improve physical abilities of…
- Conditions
- Mitochondrial Diseases, Maternally Inherited Diabetes and Deafness (MIDD), Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS), Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation
- Trial name
- KH176-301 (NCT06451757)
- Testing
- Sonlicromanol
- Where
- 10 sites in United States, Denmark and 5 more
- Volunteers
- 220 people
- Sponsor
- Khondrion BV
Stroke, Brain Computer Interface
Evaluation of an Adaptive Neurotechnology Based on Motor Imagery in Patients Who Suffered a Left Hemisphere Stroke
This randomized clinical trial will evaluate the feasibility and performance of a co-adaptive motor imagery brain-computer interface (BCI) for upper-limb rehabilitation in adults with subacute left-hemisphere stroke.
- Conditions
- Stroke, Brain Computer Interface, Motor Imagery, Neurofeedback
- Trial name
- NCT07875257
- Testing
- BCI sessions with neurofeedback, BCI sessions without neurofeedback
- Where
- Argentina
- Volunteers
- 20 people
- Sponsor
- Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia
Stroke, Intracranial Atherosclerotic Stenosis
SeQuent ® Please CIS for the Treatment of INtracranial Atherosclerotic Stenosis
This study is aiming to evaluate the safety and efficacy of SeQuent® Please CIS in the endovascular treatment of symptomatic intracranial atherosclerotic stenosis and restenosis after interventional therapy.
- Trial name
- SPINAS (NCT06047964)
- Testing
- DCB, POBA
- Where
- 9 sites in China
- Volunteers
- 281 people
- Sponsor
- B. Braun Medical International Trading Company Ltd.
Cerebrovascular Stroke
Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke
The purpose of this study is to examine how different areas in the brain interact with each other and how using brain imaging and brain stimulation approaches can influence these interactions.
- Trial name
- NCT02465034
- Testing
- Transcranial Magnetic Stimulation, Traditional Paired Associative Stimulation, Median Nerve Stimulation
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Emory University
Acute Coronary Syndrome, Ischemic Stroke
Study to Assess Pharmacokinetics, Pharmacodynamics and Safety of Tiprogrel in Healthy Subjects
This study is designed to evaluate the pharmacokinetics, pharmacodynamics and safety in healthy subjects with multiple administration of Tiprogrel.
- Trial name
- NCT06584812
- Testing
- Tiprogrel, Clopidogrel, Ticagrelor
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Tianjin Institute of Pharmaceutical Research Co., Ltd
Stroke, Stroke, Ischemic
Understanding the Need and Feasibility of Transitional Care Training Program Among Family Caregivers of Geriatric Stroke Survivors in Pakistan
The main intention of the study is to understand the need and feasibility of transitional care training program among family caregivers of geriatric stroke survivors in Pakistan
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- NCT06341881
- Testing
- Transitional Care Training Program
- Where
- 3 sites in Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Acute Ischemic Stroke
Evaluation of the Safety and Efficacy of Hemacord HPC, Cord Blood in Subjects With Acute Ischemic Stroke
This is a phase one study investigating the safety and efficacy profile of allogeneic cord blood hematopoietic progenitor cells (HPC, Cord Blood), when administered by intravenous infusion and intrathecal injection, in subjects…
- Trial name
- NCT03735277
- Testing
- HPC, Cord Blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- BHI Therapeutic Sciences
Ischemic Stroke
Evaluation of Clinical Decision Support System for Scoring of ASPECT Score Using Brain CT Images
cASPECTS is a software that has been pre-learned based on ASPECTS Score of ischemic stroke patients using brain CT images, and clinical decision support system for scoring ASPECTS score by automatically analyzing brain CT images…
- Trial name
- NCT04983927
- Testing
- cASPECTS
- Where
- South Korea
- Volunteers
- 326 people
- Sponsor
- Heuron Inc.
Stroke
VAlidity and Reliability of the Telephone Interview Form for Stroke Outcome Evaluation
The investigators combined the mRS questionnaire and BI questionnaire and then developed a telephone interview form as a simple questionnaire with internal rules.
- Trial name
- ARISE (NCT04062188)
- Testing
- Telephone Interview Form
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Dongzhimen Hospital, Beijing
Stroke, Psychological Well-Being
Aspirational Rehabilitation Coaching for Holistic Health (ARCH): A Pilot Pre-Post Experimental Study
The ARCH programme is a novel, strength-based, dyadic, multicomponent psychosocial intervention that blends together psychoeducation, psychosocial support and self-compassion practices to aid first-time stroke survivors and their…
- Conditions
- Stroke, Psychological Well-Being, Psychosocial Functioning
- Trial name
- NCT06596551
- Testing
- Pre-Post ARCH Intervention
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Ischemic Stroke, Ischemic Cerebrovascular Disease
Clinical Evaluation of New Biomarkers for Ischemic Cerebrovascular Disease
The goal of this single-center prospective observational study is to identify and evaluate new biomarkers for ischemic cerebrovascular disease (ICVD) to aid in early diagnosis, individualized treatment planning, and prognosis…
- Trial name
- NCT06890702
- Testing
- biomaker levels
- Where
- 2 sites in China
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Hemiplegia
The Effect of Virtual Reality-Mediated Rehabilitation in Ischemic Stroke Patients
The aim of the study was to investigate the effectiveness of virtual reality-mediated upper extremity rehabilitation added to the conventional rehabilitation program on upper extremity, quality of life, range of motion and…
- Trial name
- NCT05869786
- Testing
- Virtual Reality Mediated Upper Extremity Rehabilitation (SensoRehab®), conventional rehabilitation program, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University
Acute Ischemic Stroke
A Phase 2a Study to Evaluate the Dose-response, Safety, Tolerability, Efficacy, and Population Pharmacokinetics of Intravenous NTS-521 Infusions in the Early Recovery Treatment From Acute Ischemic Stroke
This is a trial to evaluate the safety and effect of three intravenous (IV) doses of NTS-521 for the early recovery treatment of acute ischemic stroke (AIS). Participants will be followed for 90 days.
- Trial name
- ACT-IVATE (NCT07742098)
- Testing
- NTS-521
- Volunteers
- 140 people
- Sponsor
- NeuroTrauma Sciences, LLC
Stroke, Cerebrovascular Accident
Robot-assisted Rehabilitation of the Upper Limb in Acute and Subacute Post-stroke Patients
The goal of this study is to determine if robot aided rehabilitation therapy can be equivalent to or more effective than conventional rehabilitation therapy at promoting functional recovery of the paretic upper limb in acute and…
- Conditions
- Stroke, Cerebrovascular Accident, Upper Extremity Paresis
- Trial name
- NCT01102309
- Testing
- Robot therapy (NeReBot), Conventional therapy
- Where
- Italy
- Volunteers
- 27 people
- Sponsor
- Eremo Hospital, Arco
Stroke
Effect of an Electromagnetic Trainer on Gait and Balance Recovery After Stroke
This study aims to evaluate the effectiveness of an electromagnetic trainer in improving lower limb motor function, gait, and balance in patients after cerebral stroke.
- Trial name
- NCT07898657
- Testing
- Electromagnetic trainer, Standard medical rehabilitation
- Where
- 2 sites in Kazakhstan
- Volunteers
- 80 people
- Sponsor
- Karaganda Medical University
Subcortical Aphasia, Ischemic Stroke
The Effect of Venlafaxine on Language Function in Patients With Subcortical Aphasia: A fMRI Study
Previous studies have demonstrated that venlafaxine significantly improves the language function of healthy subjects and increase of fMRI activation in cortical language area.
- Trial name
- NCT03588572
- Testing
- Venlafaxine hydrochloride capsules
- Where
- 2 sites in China
- Volunteers
- 43 people
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Rheumatic Heart Disease
INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Superiority
This program is a comprehensive evaluation of rheumatic valvular heart disease (RVHD), Atrial fibrillation (AF)/flutter and stroke.
- Trial name
- INVICTUS-ASA (NCT02832531)
- Testing
- Rivaroxaban (15 mg), Aspirin
- Sponsor
- Population Health Research Institute
Stroke
Impact of Gait Training on Lower Extremity Motor Function and Balance Performance in Stroke Survivors.
This randomized clinical trial evaluates and compares the effectiveness of three physiotherapy-based rehabilitation strategies in improving gait, motor function, balance, and independence in individuals recovering from stroke.
- Trial name
- NCT07066319
- Testing
- Gait Training with Proprioceptive Neuromuscular Facilitation (PNF), Gait Training with Conventional Physiotherapy, Combined PNF and Conventional Physiotherapy (without direct gait training)
- Where
- Pakistan
- Volunteers
- 99 people
- Sponsor
- University of Lahore
Chronic Hemorrhagic Stroke
Alexander Technique, Routine Physical Therapy, Balance, Posture, Functional Mobility , Chronic, Hemorrhagic, Stroke
MATERIALS AND METHODS Design: The randomized controlled trial. Setting: Nusrat Abdul Rauf Centre for Enablement, Faisalabad. Sample size:40 in each group.
- Trial name
- NCT05255809
- Testing
- Alexander Technique + Routine Physical Therapy, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- University of Lahore
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