Clinical trials: Stroke Assessment
Acute Ischemic Stroke, Mechanical Thrombectomy
Rapid Local Ischemic Postconditioning in Acute Ischemic Stroke
The objective of this clinical trial is to determine whether rapid local ischemic postconditioning (RL-IPostC) is effective in preventing brain edema and safe in acute ischemic stroke (AIS) patients treated with mechanical…
- Conditions
- Acute Ischemic Stroke, Mechanical Thrombectomy, Ischemic Postconditioning, Brain Edema
- Trial name
- RAPID-SAVE (NCT06307743)
- Testing
- rapid local ischemic postconditioning
- Volunteers
- 135 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Stroke
Evaluation of Diagnostic Criteria for Chronic Critical Limb Ischemia
Chronic critical limb ischemia (CCI) is the most severe clinical form of occlusive arterial disease. Its prognosis is terrible, mortality estimated at 50% in five years.
- Trial name
- CRIMI (NCT02834143)
- Testing
- No intervention
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Ischemic Stroke
Efficacy Study of Huatuo Zaizao Pills in Improving of Neural Function in Acute Ischemic Stroke
The purpose of this study is to determine the efficacy of Huatuo Zaizao Pills in improving neural function and life quality in patients with acute ischemic stroke in China.
- Trial name
- HTZZP-INF (NCT01758536)
- Testing
- Huatuo Zaizao Pills
- Where
- 4 sites in China
- Volunteers
- 1,100 people
- Sponsor
- Huashan Hospital
Acute Ischemic Stroke
Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic Stroke
The primary objective of the study is to assess the clinical effects of natalizumab versus placebo in acute ischemic stroke on clinical measures of functional independence and activities of daily living.
- Trial name
- ACTION2 (NCT02730455)
- Testing
- natalizumab
- Where
- 53 sites in United States, Germany and 2 more
- Volunteers
- 277 people
- Sponsor
- Biogen
Stroke, CVA (Cerebrovascular Accident)
Translation And Psychometric Testing Of The Turkish Version Of Fugl-Meyer Assessment
The aim of this methodological study is to adapt the Fugl-Meyer assessment to Turkish culture and to test its validity and reliability in acute phase stroke patients.
- Conditions
- Stroke, CVA (Cerebrovascular Accident), Hemiplegia and/or Hemiparesis Following Stroke
- Trial name
- FMA-TR (NCT05823298)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke, Spinal Cord Injuries
ZEPU-AI3 Lower Limb Feedback Robot Training Study
Lower limb motor dysfunction resulting from stroke, spinal cord injury, or other neurological disorders substantially limits mobility, independence, and quality of life.
- Conditions
- Stroke, Spinal Cord Injuries, Gait Disorders
- Trial name
- ZEPUAI3RCT (NCT07705906)
- Testing
- ZEPU-AI3 Lower Limb Feedback Training and Evaluation Robot, Conventional Rehabilitation
- Where
- Bangladesh
- Volunteers
- 32 people
- Sponsor
- Bangladesh Medical University
Assessment of Intravascular Volume Status in Mechanically Ventilated Critically Ill Patients
Evaluation of Jugular Venous Distensibility Index in Intravascular Fluid Management and Comparison of the Effectiveness of Noninvasive and Minimally Invasive Methods
Assessment of intravascular volume status is an important component of hemodynamic management in critically ill patients. Several noninvasive and minimally invasive parameters, including the pleth variability index (PVI), pulse…
- Trial name
- NCT07807709
- Testing
- Pleth variability index, Pulse pressure variation, Stroke volume variation
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Post-stroke Spasticity
Pain During Injection With Botulinum Toxin in Post-stroke Spasticity Treatment
The aim of the study was to analyze which step of the procedure of toxin botulinum injection is the most painful between skin break-in, electric stimulation, injection and needle withdrawal.
- Trial name
- DOLOTOX (NCT03251521)
- Testing
- pain rating during injection with botulinum toxin
- Volunteers
- 46 people
- Sponsor
- University Hospital, Grenoble
Stroke, Post-stroke Depression
Physical Capacity Building for Chronic Stroke
Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery.
- Trial name
- NCT07039305
- Testing
- Physical capacity training for chronic stroke - building aerobic capacity and muscle strength
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Medical University of South Carolina
Hemiplegia, Stroke, Acute
Effects Of Sensory Training and Electrical Stimulation on Sole of The Foot Sensations in Patients With Acute Hemiplegia
The aim of this study is to investigate the effects of the sole of foot sensory education and electrical stimulation on proprioceptive and cortical senses in patients with acute hemiplegia.
- Conditions
- Hemiplegia, Stroke, Acute, Sensory Disorders
- Trial name
- NCT04252092
- Testing
- Sensory training, Electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yeditepe University
Cerebral Infarction
Physical Activity After Stroke: How Does it Effect Chronical Inflammation and Insulin Sensitivity
Decreased insulin sensitivity is and independent risk factor for stroke despite glycemic control. It is known that physical exercise increases insulin sensitivity in healthy subjects.
- Trial name
- NCT00376207
- Testing
- Physical exercise
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Bispebjerg Hospital
Acute Ischaemic Middle Cerebral Artery Stroke
A Study to Evaluate the Efficacy and Safety of Piracetam on Aphasia After Acute Ischemic Cerebral Artery Stroke
The aim of this study was to confirm the efficacy of piracetam after 12 weeks of treatment on the aphasic status of subjects suffering from aphasia after acute ischemic middle cerebral artery stroke and having received their…
- Trial name
- NCT01883011
- Testing
- Piracetam
- Where
- 44 sites in Argentina, Austria and 13 more
- Volunteers
- 571 people
- Sponsor
- UCB S.A. - Pharma Sector
Minor Stroke
Early-phase Telecare Programs for Minor Stroke
Minor strokes (few acute neurological symptoms ; NIHSS score <5), represent almost 65% of cerebrovascular ischemic events. The increasing incidence of stroke in people under 65, together with advances in diagnostic and…
- Trial name
- COGaDOM (NCT06306144)
- Testing
- Psychoeducation, Computerised Cognitive Stimulation, Usual Care
- Where
- 3 sites in France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Acute Ischemic Stroke
A Study to Evaluate the Intracranial Arterial Recanalization With Multiple Doses of LT3001 Drug Product in AIS Participant
This is a phase II, open-label, single-arm, exploratory study to evaluate the intracranial arterial recanalization of multiple doses of LT3001 drug product in participant with acute ischemic stroke (AIS)
- Trial name
- NCT07890298
- Testing
- LT3001 Drug Product
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Lumosa Therapeutics Co., Ltd.
TBI, Stroke
Virtual Reality and Social Cognition After Acquired Brain Injury
The study aim is to improve assessment and understanding of social cognitive impairment after acquired brain injury by developing and validating a virtual reality version of The Awareness of Social Inference Test (TASIT).
- Conditions
- TBI, Stroke, Acquired Brain Injury, Brain Injuries
- Trial name
- NCT05309005
- Testing
- VR TASIT, DT TASIT
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Stroke
Study of the Metrological Properties of Two Assessment Grids of the Driving Capacity After a Cerebrovascular Accident (ROADTRIP)
Precise recommendations concerning the methods of evaluation for the resumption of the driving after a not evolutionary stroke were recommended recently by the High Authority of Health.
- Trial name
- ROADTRIP (NCT03977506)
- Testing
- On-road driving evaluation
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hemiplegia, Cerebrovascular Accident
The Effects of the Swiss Ball on Cerebral Vascular Accident
The objective of this study was to investigate the effects of the Swiss ball on patients with hemiplegia due to CVA.
- Trial name
- NCT00735033
- Testing
- Physiotherapy with Swiss Ball
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fortaleza University
Acute Ischemic Stroke
Evaluation of Xueshuantong in Patients With AcutE IschemiC STroke
The aim is to assess the effects and harms of Xueshuantong lyophilized powder versus placebo in patients with acute ischemic stroke when initiated within 72 hours of symptom onset.
- Trial name
- EXPECT (NCT04415164)
- Testing
- Xueshuantong lyophilized powder, Guidelines-based standard care
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Dongzhimen Hospital, Beijing
Acute Ischemic Stroke
DS1040b/Aspirin Drug/Drug Interaction Study
This is a phase 1, open label, single dose study, after 5 days of aspirin treatment, in healthy male and female subjects. It is hypothesized that co-administering DS-1040b with aspirin at steady state will be safe and well…
- Trial name
- NCT02071004
- Testing
- DS-1040b, Aspirin
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Daiichi Sankyo
Fabry Disease
Alternative Dosing and Regimen of Replagal to Treat Fabry Disease
The main goal of this study is to assess the pharmacodynamic effects of different or more frequent doses of Replagal compared to the standard dosing regimen.
- Trial name
- NCT00075244
- Testing
- Replagal
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
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