Clinical trials: Stroke Ischemic
Stroke, Gait, Hemiplegic
Assessing the Reliability and Validity of 4-meter and 10-meter Walking Test
The 4-meter walk test and 10-meter walk test is currently applied to assess gait speed.These tools are frequently used in clinical trials and were also shown to be reliable measurement methods.
- Conditions
- Stroke, Gait, Hemiplegic, Cerebral Infarction, Cerebrovascular Disorders
- Trial name
- NCT04919772
- Testing
- Assessment
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universitat Internacional de Catalunya
Acute Ischemic Stroke
Association of Prophylactic Use of Stress Ulcer Drugs and Clinical Outcomes in Patients With Acute Anterior Circulation Thrombectomy
Ischemic stroke accounts for a relatively high proportion of strokes. In recent years, intravenous thrombolysis and endovascular therapy have significantly improved the revascularization rate in patients with large vessel…
- Trial name
- NCT05845372
- Where
- 19 sites in China
- Volunteers
- 2,592 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Subjects With Acute Ischemic Stroke
The Efficacy and Safety of Edaravone Dexborneol Sequential Therapy in the Treatment of Patients With AIS
SIM0308-302 is a multicenter, randomized, double-blind, placebo-controlled clinical III trial with the primary objective of evaluating the efficacy of Edaravone Dexborneol sequential therapy, consisting of Edaravone Dexborneol…
- Trial name
- NCT06176781
- Testing
- Edaravone Dexborneol Sequential Therapy
- Volunteers
- 880 people
- Sponsor
- Simcere Pharmaceutical Co., Ltd
Stroke Acute, Endovascular Treatment
Advancing Reperfusion Therapy for Ischemic Stroke: Safety and Efficacy of Anakinra for Futile Reperfusion Following Endovascular Treatment in Patients With Acute Ischemic Stroke
The investigators initiated a multicenter, prospective, randomized, open label, blinded-endpoint (PROBE) controlled trial to explore the safety and efficacy of different dose of Anakinra compared to standard medical care for…
- Trial name
- ARTS-SAFE (NCT07423975)
- Testing
- High-dose Anakinra, Low-dose Anakinra, Standard medical treatment
- Where
- 6 sites in China
- Volunteers
- 159 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke, Upper Extremity Weakness
Memantine for Enhanced Stroke Recovery
This will be a randomized double blind placebo-controlled pilot study using a repeated measures design in which participants with acute ischemic stroke and upper extremity weakness are randomized to either drug or placebo
- Trial name
- NCT02144584
- Testing
- Memantine XR
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Acute Stroke
Danhong Injection in the Treatment of Acute Ischemic Stroke
The purpose of this study is to determine whether Danhong injection is effective in the treatment of acute ischemic stroke.
- Trial name
- NCT01677208
- Testing
- Danhong injection, Standard medical care
- Where
- 62 sites in China
- Volunteers
- 1,503 people
- Sponsor
- China Academy of Chinese Medical Sciences
Acute Ischemic Stroke
Efficacy of Semaglutide in Improving Neurological Outcomes After Endovascular Thrombectomy for Acute Ischemic Stroke: A Randomized Double-Blind Controlled Trial
The trial will be a randomized, double-blind, controlled, single-center trial. The purpose of this trial is to determine the efficacy and safety of semaglutide in improving neurological outcomes after endovascular thrombectomy…
- Trial name
- STARS (NCT07030621)
- Testing
- Semaglutide 0.5 mg, Normal Saline
- Where
- China
- Volunteers
- 436 people
- Sponsor
- RenJi Hospital
Stroke, Dementia
Predictors for Poststroke Outcomes: Tel Aviv Brain Acute Stroke Cohort Acute Stroke Cohort (TABASCO)
Background: Recent studies have demonstrated that even mild stroke survivors experience residual damage, which persists and in fact increases in subsequent years.
- Conditions
- Stroke, Dementia, Cerebrovascular Disorders, Alzheimer's Disease
- Trial name
- TABASCO (NCT01926691)
- Where
- Israel
- Volunteers
- 575 people
- Sponsor
- Eli Sprecher, MD
Ischemic Stroke, Patent Foramen Ovale
Patent Foramen Ovale in Cryptogenic Stroke Study
The study sought to assess the rate of recurrent stroke and death in stroke patients with a patent foramen ovale randomized to treatment with warfarin or aspirin. This was a multicenter study conducted at 48 U.S. Institutions.
- Trial name
- PICSS (NCT00697151)
- Testing
- Warfarin, Aspirin
- Where
- United States
- Volunteers
- 630 people
- Sponsor
- Columbia University
Ischemic Stroke, Hemiplegia
Evaluating the Therapeutic Effect of Scalp Acupuncture Treatment for Motor Dysfunction in Ischemic Stroke Patients
The investigators design a randomized, control study to evaluate the therapeutic effect of scalp acupuncture using Jiao's motor area for motor dysfunction in ischemic stroke patients using the following outcomes: motor function…
- Trial name
- NCT02871453
- Testing
- Scalp Acupuncture Treatment, Rehabilitation treatment
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Intubation Complication, Stroke, Ischemic
Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning
Adults who are unconscious or severely ill and need a breathing tube connected to a ventilator are at high risk of developing a lung infection (pneumonia) within the first few days in the intensive care unit.
- Conditions
- Intubation Complication, Stroke, Ischemic, Stroke Hemorrhagic, Head Trauma
- Trial name
- PIRAMIDES (NCT06113939)
- Testing
- airway clearance, subglottic secretion aspiration, Ceftriaxone 2 grams daily
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital San Carlos, Madrid
Neurocritical Conditions, Traumatic Brain Injury
Protein Intake Dosage on the Prognosis of Neurocritical Patients
This study investigates the effect of different early protein supplementation levels (1.0-2.0g/kg/d, divided into three groups) on the prognosis of neurocritical patients, focusing on the 28-day Glasgow Coma Scale (GCS) score…
- Conditions
- Neurocritical Conditions, Traumatic Brain Injury, Ischemic Stroke
- Trial name
- NCT07295301
- Testing
- Low-Dose Enteral Protein Supplementation (Enteral Nutrition Formulas + Whey Protein Powder), Moderate-Dose Enteral Protein Supplementation (Enteral Nutrition Formulas + Whey Protein Powder), High-Dose Enteral Protein Supplementation (Enteral Nutrition Formulas + Whey Protein Powder)
- Volunteers
- 216 people
- Sponsor
- Wenshan City People's Hospital
Stroke, Acute, Stroke, Ischemic
Trustworthy Artificial Intelligence for Improvement of Stroke Outcomes
Stroke is a leading cause of death and disability worldwide. The clinical validation of explainable and interpretable Artificial Intelligence (AI) solutions to assist a timely, personalised management of the acute phase of…
- Conditions
- Stroke, Acute, Stroke, Ischemic, Stroke
- Trial name
- TRUSTroke (NCT06710028)
- Testing
- NORA
- Where
- 3 sites in Belgium, Italy and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sleep Apnoea, Cerebral Palsy
Ischaemic Stroke and Sleep Apnea in Northern Part of Finland
Obstructive sleep apnoea is a risk factor for ischaemic stroke. study hypothesis: In prospective study the investigators want to know how many ischaemic stroke patients have sleep apnoea and does thrombolysis play a role in…
- Trial name
- NCT01861275
- Testing
- Nasal CPAP
- Where
- Finland
- Volunteers
- 256 people
- Sponsor
- University of Oulu
Ischemic Stroke, Cardioembolic Stroke
Detecting Cardiac Thrombi in Acute Ischemic Stroke on Cardiac CT Versus Transoesophageal Echocardiography
Rationale: Cardiac CT acquired during the acute stroke imaging protocol (acute cardiac CT) has recently been shown to have a superior diagnostic yield than transthoracic echocardiography, which is currently the most commonly used…
- Conditions
- Ischemic Stroke, Cardioembolic Stroke, Thrombus; Embolism, Left Atrial Thrombosis
- Trial name
- MtH-DETECT (NCT06585228)
- Testing
- Cardiac Computed Tomography, Transesophageal echocardiography, Repeated Cardiac Computed Tomography
- Where
- Netherlands
- Volunteers
- 39 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Post-stroke Disorders
"Cognitive, Motor and Sleep Evaluation in Patients With Ischemic Stroke of Basal Ganglia After Thrombectomy"
The goal of this interventional study is to learn about the clinical outcomes of acute ischemic stroke treated with mechanical thrombectomy resulting in a selective ischemia of the basal ganglia.
- Trial name
- CMS - SBGT (NCT05878002)
- Testing
- polysomnography
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stroke, Vascular Occlusion
REperfusion Therapy for Acute Ischemic STrOke Due to Large aRtEry Occlusion
The aim of the study was to establish a clinical and advanced imaging database of acute ischemic stroke patients treated with mechanical thrombectomy due to large vessel occlusion of anterior circulation within 24 hours from…
- Conditions
- Stroke, Vascular Occlusion, Endovascular Treatment, Mechanical Thrombectomy
- Trial name
- RESTORE (NCT05311605)
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Hemorrhages, Acute Ischemic Stroke
AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Intracranial Hemorrhages, Acute Ischemic Stroke, Hydrocephalus, Cerebral Infarction
- Trial name
- AI-REACT (NCT06018545)
- Testing
- Ground truthing, Reading
- Where
- 4 sites in United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Stroke, Atrial Fibrillation (AF)
Early Anticoagulation Therapy After Endovascular Treatment for Acute Ischemic Stroke With Atrial Fibrillation
The goal of this clinical trial is to learn whether starting a direct oral anticoagulant (DOAC) early after endovascular treatment works to improve outcomes in patients with ischemic stroke related to atrial fibrillation.
- Trial name
- EATAF (NCT07849777)
- Testing
- Early Initiation of DOAC Therapy, Antiplatelet Bridging Followed by DOAC Therapy
- Where
- 2 sites in China
- Volunteers
- 474 people
- Sponsor
- The Fourth Affiliated Hospital of Soochow University
Ischemic Stroke
The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Stroke
This randomized controlled trial investigates the effect of a single dose of glucagon-like peptide-1 (GLP-1) receptor agonist in the subacute phase of stroke in humans.
- Trial name
- EGRABIS1 (NCT02829502)
- Testing
- Byetta, Normosaline
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Christina Kruuse