Clinical trials: Stroke Technique
Aphasia Non Fluent, Stroke
Mirror Speech Entrainment: A Novel Technique for Voice Personalized Speech Entrainment for Nonfluent Aphasia
The goal of this clinical trial is to test the use of voice personalization through artificial intelligence (AI) voice cloning on speech entrainment tasks to improve language production of persons with aphasia (PWA).
- Conditions
- Aphasia Non Fluent, Stroke, Aphasia
- Trial name
- MSE (NCT06829420)
- Testing
- Mirror speech entrainment, Traditional speech entrainment: auditory-only, Traditional speech entrainment: auditory-visual
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of South Florida
Fluid Responsiveness
Accuracy of Pulse Pressure Variation and of Pleth Variability Index to Predict the Response to a Fluid Challenge
The aim of this study is to compare the accuracy of Pleth Variability Index (Radical 7 device) and of Pulse Pressure Variation (Nexfin device) with the Doppler measurement of stroke volume (esophageal Doppler) to detect the…
- Trial name
- Nexfin2 (NCT02040948)
- Testing
- - Nexfin (Pulse Pressure Variation) - Radical 7 (Pleth Variability Index) - CardioQ (stroke volume)
- Where
- 2 sites in France
- Volunteers
- 68 people
- Sponsor
- Hopital Foch
Acute Ischemic Stroke
Anesthesia Technique and Outcomes in Mechanical Thrombectomy for Acute Ischemic Stroke
This retrospective cohort study examined clinical outcomes in patients who underwent mechanical thrombectomy for acute ischemic stroke under general anesthesia or sedoanalgesia.
- Trial name
- NCT07422649
- Testing
- General Anesthesia, Sedoanalgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 481 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Hemiparesis
Post-stroke Motor Rehabilitation Using Functional Near-infrared Spectroscopy-based Brain-computer-interface
Chronic stroke survivors suffering from weaknesses or movement difficulties in their hand/arm are provided a system to aid in at-home rehabilitation for 6 weeks.
- Trial name
- fNIRS-PROMOTE (NCT05258591)
- Testing
- Axem Home
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Axem Neurotechnology Inc.
Stroke
Ventilation Strategies, Anesthetic Techniques and Cerebral Oxygenation in the Beach Chair Position
The seated or "beach chair" position during surgery and general anesthesia decreases brain oxygen levels and can result in stroke. As such, poor neurological outcome following beach chair positioning is a growing concern.
- Trial name
- NCT01535274
- Testing
- Inspired oxygen fraction / end tidal carbon dioxide
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Michigan
Symptomatic Paroxysmal Atrial Fibrillation
Mesh Ablator Versus Cryoballoon Pulmonary Vein Ablation of Symptomatic Paroxysmal Atrial Fibrillation
The purpose of this prospective randomized single-center trial is to compare efficiency and safety of two pulmonary vein ablation systems in patients with symptomatic paroxysmal atrial fibrillation using the Arctic Front® versus…
- Trial name
- MACPAF (NCT01061931)
- Testing
- Arctic Front® catheter vs. HD Mesh Ablator® catheter
- Where
- Germany
- Volunteers
- 108 people
- Sponsor
- Charite University, Berlin, Germany
Stroke, Hemiplegia
Air Stacking-Assisted Diaphragmatic Breathing in Stroke
The purpose of this study is to investigate whether a diaphragmatic breathing exercise using the air stacking technique can improve respiratory function and trunk control in patients with stroke.
- Trial name
- NCT07577076
- Testing
- Air stacking-assisted diaphragmatic breathing, diaphragmatic breathing
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- jang ji-hun
Stroke Patient, Caregiver
Improving Resilience and Quality of Life of Stroke Patients
This study aims to (1) test the effect of Family System Care and Theme Care Action Module on resilience, family function, self-efficacy, and quality of life for stroke patients and their families and caregivers; and (2) interview…
- Trial name
- NCT05291442
- Testing
- To integrate Family System Care and Theme Care Action Module
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Chung Shan Medical University
Stroke, Acceptance and Commitment Therapy
A Mixed-methods Evaluation of an Adapted Acceptance and Commitment Therapy (ACT) Group for Stroke Survivors
Stroke is one of the main causes of acquired adult disability in the UK. Many psychological problems can also occur post-stroke; this has a marked impact on health service usage.
- Trial name
- NCT03295032
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- 4 sites in United Kingdom
- Volunteers
- 53 people
- Sponsor
- Cardiff University
Stroke
The Feasibility and Acceptability of a Gait Training Program Based on Telerehabilitation After Stroke
Gait impairments following stroke significantly reduce functional mobility, making walking recovery a primary rehabilitation goal to improve safety, speed, and quality of life while reducing fall risk.
- Trial name
- NCT07623018
- Testing
- STEP-Tech intervention
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 12 people
- Sponsor
- University of Exeter
Cerebrovascular Accident
Investigation of Changes in Lower Limb Muscles After Cerebrovascular Accident
The aim of this study is to investigate lower limb muscles after cerebrovascular accident
- Trial name
- NCT04607486
- Testing
- 3DfUS and IPSA of leg muscles
- Where
- Belgium
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy, Stroke
A Longitudinal Study of Motor Control and Brain Images in Patients With Brain Damage
The primary goal of this study is to establish and evaluate an image-based biomarker for the impaired motor control and sensory information processing present in Cerebral palsy (CP) and stroke patients.
- Trial name
- NCT01883960
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Hemiplegia
Tele-rehabilitation in the Home With Gaming as a Method of Improving Upper Extremity Function After Stroke
The purpose of the study is to determine whether a novel computer gaming hand exercise regimen would improve hand and arm function and be feasible in people with hemiplegia after Stroke affecting the hand.
- Trial name
- NCT02494362
- Testing
- Computer gaming hand exercise regimen.
- Where
- 2 sites in Canada
- Volunteers
- 15 people
- Sponsor
- University of Manitoba
Acute Ischemic Stroke
Combined Use of Contact Aspiration and the Stent Retriever Technique Versus Stent Retriever Alone for Recanalisation in Acute Cerebral Infarction
Mechanical thrombectomy (MT) with a stent retriever (SR) device is now the standard intervention in ischemic stroke with large vessel occlusion. Favorable outcome is strongly associated with the successful reperfusion status.
- Trial name
- ASTER2 (NCT03290885)
- Testing
- Combined contact aspiration/Stent Retriever Technique, Stent retriever technique
- Where
- 11 sites in France
- Volunteers
- 408 people
- Sponsor
- Hopital Foch
Posterior Circulation Brain Infarction
Choice of Anesthesia for Endovascular Treatment of Acute Ischemic Stroke in Posterior Circulation
There is few randomized controlled clinical to investigated the impact of anesthetic type on outcome in patients with acute ischemic stroke in posterior cerebral circulation.
- Trial name
- CANVAS-II (NCT03317535)
- Testing
- General anesthesia, Local anesthesia/concious sedation, Spontaneous breath
- Where
- 2 sites in China
- Volunteers
- 93 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Atrial Fibrillation
Novel Methods for Arrhythmia Detection: Preliminary Study
Approximately 20-25% of strokes are of cardioembolic origin, atrial fibrillation (AF) being a significant cause of cardioembolic strokes. AF is often symptomless and intermittent, making its detection a clinical challenge.
- Trial name
- NCT03721601
- Testing
- Heart rate monitor chest strap, Wrist band photoplethysmography
- Where
- 3 sites in Finland
- Volunteers
- 220 people
- Sponsor
- Kuopio University Hospital
Stroke Syndrome Sequela Spasticity
Perfetti Method on Upper Extremity Spasticity of Stroke Patient
This study objective is to study the immediate effect of Perfetti Method in reducing spasticity of upper extremity in stroke patients at the Department of Physical Medicine,Faculty of Medicine Ramathibodhi Hospital, Thailand.
- Trial name
- NCT04869748
- Testing
- Perfetti method, passive stretching
- Where
- Thailand
- Volunteers
- 14 people
- Sponsor
- Mahidol University
Stroke
Investigation of Factors Causing Knee Hyperextension During Walking in Chronic Stroke Patients
In this study, it is aimed to examine the factors that cause knee hyperextension in chronic stroke patients. Although the presence of weakness or spasticity in the quadriceps muscle, weakness or spasticity in the plantar flexors…
- Trial name
- NCT05513781
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Hacettepe University
Stroke, Emotionality
Piloting the Attention Training Technique for Post-Stroke Emotionalism
The aim of this mutli-phasic systematic case series is to explore if the Attention Training Technique (ATT) can improve symptoms of Post Stroke Emotionalism.
- Conditions
- Stroke, Emotionality, Pseudobulbar Affect, Lability Emotional
- Trial name
- NCT06457126
- Testing
- Attention Training Technique
- Where
- 2 sites in United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Manchester
Stroke, Depressive Symptoms
Instant Message-delivered Brief Internet-based Cognitive Behavioural Therapy (iCBT) for Post-stroke Depression
Around one third of stroke survivors develop depression at any point of time following the stroke event. Post-stroke depression (PSD) is associated with negative care outcomes including poorer function, longer hospital stays…
- Conditions
- Stroke, Depressive Symptoms, Mobile Phone Use
- Trial name
- NCT05892965
- Testing
- iCBT-based EMI
- Where
- 7 sites in Hong Kong
- Volunteers
- 160 people
- Sponsor
- The University of Hong Kong