Clinical trials: Stroke Treatment
Pediatric Hemiparesis
Brain Stimulation and Hand Training in Children With Hemiparesis
Hemiparetic cerebral palsy influences motor function in children during development and throughout their lifetime. The deficits one sees are the result both of the congenitally induced brain lesion and the subsequent plasticity…
- Trial name
- NCT02250092
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Stroke
Development of a Tailored Life-Sustaining Treatment Decision Support Intervention for Stroke Surrogate Decision Makers
The trial is testing an investigator-developed decision support tool for surrogate decision makers for stroke patients that are unable to make medical decisions for themselves.
- Trial name
- NCT03427645
- Testing
- Decision tool
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Acute Ischemic Stroke
Hyperbaric Oxygen After Stroke Thrombectomy: A Multicenter Randomized Trial on Safety and Efficacy
1. The goal of this clinical trial is to evaluate the efficacy and safety of hyperbaric oxygen (HBO)in stroke patients after endovascular treatment 2.
- Trial name
- NOTICE-1 (NCT07049692)
- Testing
- Hyperbaric Oxygen Therapy, Conventional therapy group
- Where
- 2 sites in China
- Volunteers
- 424 people
- Sponsor
- Beijing Chao Yang Hospital
Acute Ischemic Stroke, Large Vessel Occlusion
Ischemic Post-conditioning in the Treatment of Acute Ischemic Stroke
Post-ischemic adaptation is a physical brain protective treatment strategy in which an ischemic event in an organ or tissue is treated and blood flow is restored, and an ischemic stimulus is given to local tissues to induce the…
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Intracranial Artery Occlusion With Cerebral Infarction, Endovascular Treatments
- Trial name
- NCT06456437
- Testing
- Post-conditioning Balloon dilation and contraction
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Ming Wei
Acute Ischemic Stroke, Intracranial Artery Occlusion
Intra-arterial TNK Following Endovascular Thrombectomy in Patients With Large Vessel Occlusion of Posterior Circulation
Rationale: Recently, one prospective multicenter RCT reported a potential beneficial effect of intra-arterial alteplase following successful endovascular thrombectomy (EVT) in patients with an acute intracranial large vessel…
- Conditions
- Acute Ischemic Stroke, Intracranial Artery Occlusion, Endovascular Thrombectomy
- Trial name
- NCT05684172
- Testing
- Tenecteplase, endovascular thrombectomy alone
- Where
- China
- Volunteers
- 208 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Stroke
Power-Assisted Therapeutic Electrical Stimulation to Upper Extremities
Power-assisted therapeutic electrical stimulation (TES) or conventional TES to upper extremities in acute stroke patients were performed in a randomized controlled trial. The changes in finger and hand function will be evaluated.
- Trial name
- TES (NCT00823537)
- Testing
- therapeutic electrical stimulation
- Sponsor
- Fujita Health University
Stroke
Effects of Task-Based Mirror Therapy for Post-stroke Shoulder-Hand Syndrome
The study aims to determine the effects of task-based mirror therapy on edema, pain and upper limb motor function with shoulder-hand syndrome in post stroke patients.
- Trial name
- NCT07428811
- Testing
- Task based mirror therapy, Conventional exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Cardioembolic Stroke, Multidisciplinary Communication
A Real-world Registry Study of Multidisciplinary Collaborative Diagnosis and Treatment Model for Cardioembolic Stroke
Study Title: A real-world registry of multidisciplinary collaborative diagnosis and treatment models for cardioembolic stroke Research Objectives: ① Main objective: To establish a multidisciplinary assisted diagnosis and…
- Trial name
- CSMDT (NCT05498909)
- Testing
- Multidisciplinary joint diagnosis and treatment mode
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Xiao Huang
Stroke
teleABLE to Reduce Post-Stroke Sedentary Behavior
The goal of this clinical trial to test whether a remotely delivered behavioral activation-based intervention called "teleABLE" works better than a health education intervention for (1) reducing sitting time and (2) improving…
- Trial name
- NCT06312709
- Testing
- teleABLE (telehealth-delivered Activating Behavior for Lasting Engagement), Health Education
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Minnesota
Stroke
Encouragement-induced Movement Therapy in Daily Life
Stroke places a major burden on health care and society. It often leads to a hemiparesis. Intensive stroke rehabilitation speeds up recovery.
- Trial name
- ISEAR (NCT03294187)
- Testing
- Wrist-worn wearables
- Where
- 3 sites in Switzerland
- Volunteers
- 42 people
- Sponsor
- University of Zurich
Stroke, Acute
Mirror Therapy Education for Acute Stroke Patients
In Canada, the number of stroke survivors is equivalent to the size of one of the four Atlantic Provinces. The incident rate of stroke has been increasing steadily since 1995.
- Trial name
- NCT04542772
- Testing
- Mirror Therapy, Regular Rehabilitation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Health Sciences North Research Institute
Shoulder Pain
Electrical Stimulation for the Treatment of Post-Stroke Shoulder Pain
Post-stroke shoulder pain is defined as pain in the shoulder area that starts after a person has had a stroke. The SPR System is an investigational device that is being studied for the relief of post-stroke shoulder pain.
- Trial name
- NCT01094301
- Testing
- The SPR System
- Where
- 4 sites in United States
- Volunteers
- 28 people
- Sponsor
- SPR Therapeutics, Inc.
Sickle Cell Anemia
Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea
The primary goal of the Phase III TWiTCH trial is to compare 24 months of alternative therapy (hydroxyurea) to standard therapy (transfusions) for pediatric subjects with sickle cell anemia and abnormally high (≥200 cm/sec)…
- Trial name
- TWiTCH (NCT01425307)
- Testing
- Hydroxyurea
- Volunteers
- 159 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Stroke, Acute, Intracerebral Hemorrhage
The Akershus Study of Ischemic Stroke and Thrombolysis -1
This observational study comprises consecutively patients with cerebrovascular diseases admitted to the Stroke Unit at Akershus University Hospital in Norway.
- Conditions
- Stroke, Acute, Intracerebral Hemorrhage, Stroke, Ischemic, TIA
- Trial name
- ASIST-1 (NCT05378490)
- Where
- Norway
- Volunteers
- 6,000 people
- Sponsor
- University Hospital, Akershus
Vertebral Artery Dissection, Cerebrovascular Accident
Changes in Cerebral Blood Flow With Spinal Manipulative Therapy vs. Voluntary Motion
The investigators are performing a study to determine whether changes in blood flow occur in the neck and back of the brain following a series of head positions and a manipulation of the upper neck.
- Conditions
- Vertebral Artery Dissection, Cerebrovascular Accident, Cerebrovascular Stroke
- Trial name
- NCT01205490
- Testing
- head positions and spinal manipulation
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Canadian Memorial Chiropractic College
Stroke, Cerebral Palsy
Usability Testing of a Bilateral Activities of Daily Exercise Robot for Stroke Therapy
In stroke rehabilitation, unilateral training of the impaired limb after stroke is often the frequent strategy used over bilateral ones.
- Trial name
- BiADLER (NCT02882646)
- Testing
- Bi-ADLER
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke, Rehabilitation
Effect of Intensive Language Therapy in Subacute Stroke Patients
Early stroke rehabilitation is known to be an effective and essential therapy in gaining functional independence and preventing complications.
- Conditions
- Stroke, Rehabilitation, Language
- Trial name
- NCT03168373
- Testing
- language rehabilitation therapy
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Samsung Medical Center
Stroke Patients
Effect of mCIMT on Upper Extremity Functions of Stroke Patients With Right/Left Hemiplegia
The investigators aimed To analyze effect of modified constraint induced movement therapy on upper extremity functions and quality of life of subacute and chronic phase stroke patients with right/left hemisphere damage.
- Trial name
- NCT04013750
- Testing
- Modified Constraint Induced Movement Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Ischemic Stroke, Acute
Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-D )
To compare the prognosis of patients with hyperacute ischemic stroke (arriving at the emergency department between 4.5-6 hours of symptom onset) managed in a standard stroke unit adherent to guidelines versus managed in Emergency…
- Trial name
- NCT06522282
- Testing
- Emergency Stroke Unit based on 0.23-T MRI, Standard stroke unit
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Hemiplegia
Treatment Protocol for Hemiplegic Shoulder Pain
The purpose of this study is to determine if a specific stretching and strengthening protocol, in addition to current standard treatment, is more effective for treating post-stroke shoulder pain than current standard treatment…
- Conditions
- Stroke, Hemiplegia, Shoulder Pain
- Trial name
- TPHSP (NCT01232218)
- Testing
- Standard education/exercises for hemiplegic shoulder pain, Three dimensional Scapular-Humeral Mobilizations
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Toronto Rehabilitation Institute