Clinical trials: Stroke Treatment
Fluid Therapy
The Effect of Goal-directed Therapy Guided by Stroke Volume Variation and Cardiac Index in Non-severe Surgical Patients
To evaluate the application of fluid-infusion therapy with the combination of stroke volume variation (SVV) and cardiac index (CI) as the primary judgment in non-severe patients underwent resection of gastrointestinal tumor.
- Trial name
- NCT02841046
- Testing
- cardiac index, Stroke Volume Variation
- Volunteers
- 50 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Cerebral Stroke
FitMi Plus Home Therapy for Stroke Patients
The investigators will investigate the efficacy of a newly developed functional exercise device (FitMi Plus) for people in the chronic stage after a stroke compared to the FitMi Basic (i.e. without functional exercises).
- Trial name
- NCT03935425
- Testing
- FitMi Plus, FitMi Basic
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Flint Rehabilitation Devices, LLC
Obstructive Sleep Apnea, Stroke
Sleep Apnea Treatment After Stroke (SATS)
The purpose of this study is to determine if treating stroke patients who have obstructive sleep apnea with continuous positive airway pressure will improve symptoms caused by the stroke.
- Trial name
- NCT00282815
- Testing
- continuous positive airway pressure or CPAP
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Michigan
Stroke, Hemiplegia, Spastic
Condensed and Distributed Robotic Therapy in Spastic Stroke Post Botulinum Toxin Injection
The purpose of this project is to examine and compare the immediate and long-term effects of combined Botulinum toxin type A (BoNT-A) injection between condensed and distributed robot-assisted training (RT) programs in patients…
- Trial name
- NCT03321097
- Testing
- condensed RT group, distributed RT group
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke
Safety Study of External Counterpulsation as a Treatment for Acute Ischemic Stroke
The purpose of this study is to determine if external counterpulsation (ECP) is feasible to perform, tolerable, and safe as a treatment for patients with acute ischemic stroke (i.e., a blockage of one of the arteries supplying a…
- Trial name
- CUFFS (NCT00983749)
- Testing
- Full-pressure ECP
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of California, San Diego
Cerebrovascular Accident
FINGER Robot Therapy Study
The purpose of this study is to determine the effectiveness of training hand movement using FINGER robot after stroke. FINGER is a robot that measures finger movements and allows users to play computer games using those movements.
- Trial name
- NCT02048826
- Testing
- FINGER I, FINGER II
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of California, Irvine
Peripheral Artery Disease
A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease
The purpose of this study is to compare the effects of ticagrelor and clopidogrel in patients with Peripheral Artery Disease.
- Trial name
- EUCLID (NCT01732822)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 776 sites in United States, Argentina and 26 more
- Volunteers
- 13,885 people
- Sponsor
- AstraZeneca
Post-Stroke Spasticity, Cerebrovascular Accident
Study of GSK1358820 In Patients With Post-Stroke Lower Limb Spasticity
This is a study to confirm the superior efficacy of GSK1358820 over placebo in patients with equinus deformity associated with post-stroke lower limb spasticity using the Modified Ashworth Scale (MAS) ankle score.
- Trial name
- NCT00460655
- Testing
- GSK1358820
- Where
- 20 sites in Japan
- Volunteers
- 120 people
- Sponsor
- GlaxoSmithKline
Atherosclerosis, Adherence, Medication
Stroke Minimization Through Additive Anti-atherosclerotic Agents in Routine Treatment
The overarching objective of the Stroke Minimization through Additive Anti-atherosclerotic Agents in Routine Treatment (SMAART) trial is to assess whether a polypill containing fixed doses of (2/3) antihypertensives, a statin and…
- Conditions
- Atherosclerosis, Adherence, Medication, Tolerance
- Trial name
- NCT03329599
- Testing
- Polycap
- Where
- Ghana
- Volunteers
- 148 people
- Sponsor
- Northern California Institute of Research and Education
Stroke, Healthy
Use of Transcranial Direct Current Stimulation (tDCS) Coupled With Constraint Induced Movement Therapy in Stroke Patient
The purpose of this study is to determine whether noninvasive brain stimulation associated with motor learning offers an additional benefit than motor learning alone in patients with stroke.
- Trial name
- tdcs (NCT01143649)
- Testing
- transcranial direct current stimulation (tDCS), constraint induced movement therapy (CIMT), transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Atrial Fibrillation
Patient Convenience Study- NIS RELATE
The aim of this non-interventional study is to describe patient's perception of anticoagulant treatment when using Pradaxa® to prevent stroke and systemic embolism while suffering from atrial fibrillation (according to its…
- Trial name
- NCT02849509
- Testing
- Pradaxa (dabigatran), Vitamin K antagonist
- Where
- 50 sites in Indonesia, Malaysia and 3 more
- Volunteers
- 1,313 people
- Sponsor
- Boehringer Ingelheim
Stroke, Cerebrovascular Accident
Clinic-Based AMES Treatment of Stroke
This study investigates whether assisted movement with biofeedback and muscle vibration applied to the lower limb reduces impairment and improves gait.
- Trial name
- NCT00847704
- Testing
- Assisted movement and enhanced sensation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Oregon Health and Science University
Stroke
Niche Trial: Navigated Inhibitory rTMS to Contralesional Hemisphere Trial
A pivotal, prospective, multi-center, randomized, controlled, double-blinded study combining active Nexstim NBS-guided 1Hz rTMS or sham-rTMS targeting the healthy hemisphere with standardized task oriented rehabilitation will be…
- Trial name
- NICHE (NCT02089464)
- Testing
- NBS-guided rTMS, Task oriented rehabilitation
- Where
- 12 sites in United States
- Volunteers
- 199 people
- Sponsor
- Nexstim Ltd
Ischemic Stroke, Hemorrhagic Stroke
BCI-FES Therapy for Stroke Rehabilitation
There are over 7 million stroke survivors in the US alone, with approximately 795,000 new cases annually. Despite the best available physiotherapy, 30-60% of stroke survivors remain affected by difficulty walking, with foot…
- Trial name
- NCT04279067
- Testing
- BCI-FES dorsiflexion therapy, Physiotherapy one hour, Physiotherapy two hours
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, Irvine
Atrial Fibrillation, Stroke
Intention to Prescribe/Take OAC Depending on the Number of Risk Diagrams , and Period for the Estimation of the Risk.
Randomized study concerning the effect of the number of risk diagrams (with treatment +/- without treatment), the period of stroke risk estimation (one year or five years) and the target of prescription (the patient with atrial…
- Trial name
- NCT02746107
- Testing
- decision aid
- Where
- Romania
- Volunteers
- 968 people
- Sponsor
- Cristian Baicus
Stroke
Robots Paired With tDCS in Stroke Recovery
The purpose of this study is to evaluate if multiple therapy sessions of Transcranial Direct Current Stimulation (tDCS non-invasive brain stimulation) combined with robotic arm therapy lead to a greater functional recovery in…
- Trial name
- NCT01726673
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Northwell Health
Atrial Fibrillation (AF), Stroke
Safety and Tolerability of Abelacimab (MAA868) vs. Rivaroxaban in Patients With Atrial Fibrillation
The purpose of the ANT-006 study is to evaluate the bleeding profile of abelacimab relative to rivaroxaban in patients with atrial fibrillation (AF) at moderate-to-high risk of stroke.
- Trial name
- AZALEA-TIMI 71 (NCT04755283)
- Testing
- Abelacimab, Rivaroxaban
- Where
- 92 sites in United States, Canada and 5 more
- Volunteers
- 1,287 people
- Sponsor
- Anthos Therapeutics, Inc.
Dysphagia, Oral Phase, Stroke, Ischemic
Lingual Endurance Exercise in Treating Post-Stroke Dysphagia
Aim 1: Determine feasibility of lingual endurance training for individuals with persistent dysphagia after ischemic stroke. Primary outcome measures: % patient adherence (# of attempted repetitions/# prescribed repetitions) and %…
- Trial name
- NCT05523973
- Testing
- Lingual Endurance Training
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Cincinnati
Stroke, Aphasia
Improving Aphasia Using Electrical Brain Stimulation
Language and communication are essential for almost every aspect of human life, but for people who have aphasia, a language processing disorder that can occur after stroke or brain injury, even simple conversations can become a…
- Trial name
- NCT04963803
- Testing
- Active transcranial direct current stimulation (tDCS), Language Specific Attention Treatment
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Syracuse University
Stroke
Telerehabilitation in the Home Versus Therapy In-Clinic for Patients With Stroke
The current study will test the effectiveness of a novel home-based telehealth system designed to improve motor recovery and patient education after stroke.
- Trial name
- NCT02360488
- Testing
- Telerehabilitation Therapy, In-Clinic Therapy
- Where
- 12 sites in United States
- Volunteers
- 124 people
- Sponsor
- University of California, Irvine