Clinical trials: Stroke Treatment
Stroke, Depression
Can Acupuncture Treat Post-stroke Depression?
An 8-week, assessor-blind, randomized controlled trial will be conducted. A total of 138 patients with post-stroke depression (PSD) will be randomly assigned to the combination acupuncture treatment (CAI) (n = 69) or least…
- Conditions
- Stroke, Depression, Stroke Sequelae
- Trial name
- PSD2 (NCT02644161)
- Testing
- Dense cranial electroacupuncture stimulation, Body acupuncture, Antidepressant
- Where
- 2 sites in Hong Kong
- Volunteers
- 91 people
- Sponsor
- The University of Hong Kong
Ischemic Stroke
Predictors of Outcome in t-PA Treated Stroke.
Stroke is among the most disabilitating diseases worldwide in terms of numbers affected and its consequences. A relatively new and well documented treatment of acute ischemic stroke today is tPA (tissue plasminogen activator…
- Trial name
- NCT01498042
- Where
- Norway
- Volunteers
- 162 people
- Sponsor
- Sorlandet Hospital HF
Acute Ischemic Stroke
COOLing of the Ischemic PENumbra in Patients With Acute Ischemic Stroke.
This study will develop and validate a novel, active/conductive combined head and neck cooling system to selectively cool the ischemic penumbra during the acute phase of stroke, reducing neuronal damage and improving stroke…
- Trial name
- PEN-Cool (NCT07844096)
- Testing
- PEN-Cool Conductive Head-and-Neck Cooling System, Standard Reperfusion Therapy / Routine Care
- Where
- 5 sites in India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Stroke, Motor Disorders
Acupuncture Treatment on Motor Dysfunction in Stroke Patients
The objective of this proposed study is to determine whether acupuncture combined with rehabilitation treatment could improve significantly motor function in ischemic stroke patients.
- Trial name
- NCT02975362
- Testing
- Acupuncture Treatment, Rehabilitation Treatment
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Stroke, Stroke, Acute
Improving Medication Self-Administration and Health After Brain Injury
The purpose of this research study is to assess medication self-administration (MSA) and the impact of three different interventions on improving medication adherence.
- Conditions
- Stroke, Stroke, Acute, Cognitive Impairment, Brain Injuries, Traumatic
- Trial name
- NCT03885674
- Testing
- Video Call Reminder Condition, Automated Text Message Reminder Condition
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Kessler Foundation
Stroke
Effects of Intensive Robot-assisted Therapy in Patients With Subacute Stroke
Robot-assisted training (RT) devices developed to date have a significant impact on stroke rehabilitation. Several research groups have developed the robotic devices and examined their efficacy on improving upper limb function…
- Trial name
- RT (NCT01767480)
- Testing
- RT, Conventional rehabilitation (CR)
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stroke, Hypothermia Treatment
Prognostic Biomarkers for Selective Intra-Arterial Cooling Infusion Combined with Endovascular Thrombectomy in Acute Ischemic Stroke Based on Proteomics and Metabolomics.
Endovascular Thrombectomy has emerged as a pivotal treatment modality for acute ischemic stroke. However, despite successful thrombus removal, a substantial proportion of patients still experience poor outcomes.
- Trial name
- NCT06665386
- Testing
- hypothermia
- Where
- China
- Volunteers
- 258 people
- Sponsor
- Capital Medical University
Sensory Neglect, Stroke
Feasibility and Effectiveness Study of Implementing Prism Adaptation as a Treatment for Spatial Neglect After Stroke
Spatial neglect is a common attention disorder after right hemisphere stroke and is associated with decreased independence and quality of life.
- Trial name
- NCT02680171
- Testing
- Prism Goggles, Non-Shifting Goggles
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Nova Scotia Health Authority
Weakness of Extremities as Sequela of Stroke, Modified Constraint Induced Movement Therapy After Stroke
Peer Group Regulated mCIMT Program for Adult Stroke Patients: Effects on Functional Activities
Each year more than 17 million people in the world are experiencing a stroke. Stroke is a major cause of mortality and one of the prevalent causes of serious disablement.
- Conditions
- Weakness of Extremities as Sequela of Stroke, Modified Constraint Induced Movement Therapy After Stroke, Upper Extremity Functional Performance After Stroke
- Trial name
- PEPS-MIT (NCT04264195)
- Testing
- Constraint-induced movement therapy: PEPS-MIT, Bimanual manipulation exercises (PEPS-Bimanual)
- Where
- Bangladesh
- Volunteers
- 140 people
- Sponsor
- Centre for the Rehabilitation of the Paralysed, Bangladesh
Stroke
Investigating Effects of High-intensity Gait Training on Gait, Balance and Depression Post-stroke
The purpose of this research is to study the improvements from walking practice that is vigorous enough to keep participants' heart rate over a certain target level during their physical therapy sessions.
- Trial name
- NCT06373107
- Testing
- High intensity gait training
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Alvernia University
Stroke
Study Impact of Nutritional Supplementary Treatment of Undernourished Stroke Patient on Functional Outcome Measures
Undernutrition after stroke is frequent and is due to cognitive impairment, visuospatial perceptive deficits, hemiparesis, depression and dysphagia.
- Trial name
- NCT00332800
- Testing
- Nutritional Supplementation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Burke Rehabilitation Hospital
Post-stroke Depression
Integrated Rehabilitation in Treating Post-stroke Depression
Post-stroke depression (PSD) is a common complication of stroke that leads to dysfunction and reduces the quality of life. PSD exacerbates cognitive dysfunction, delays the recovery process, and increases the disability…
- Trial name
- IRTPD (NCT05187975)
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 202 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Stroke Outcome Prediction Supported by Deep Learning Algorithm
STOP-stroke: STroke Outcome Prediction in the Acute Treatment Setting
The STOP-stroke project aims at improving prediction of outcome early after stroke. In order to achieve this, we need to understand reasons (important variables) for prediction in a real clinical prognostication process.
- Trial name
- STOP-STroke (NCT06534645)
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- University of Zurich
Thrombosis
Ex Vivo Test of New Stroke Treatment Using Magnetic Nanorobots
Tissue plasminogen activator (tPA) is the FDA approved thrombolytic drug for patients with acute ischemic stroke. While transcatheter endovascular therapy is widely accepted as an effective method for targeted blood vessels via a…
- Trial name
- NCT04644653
- Where
- 2 sites in Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke
Clinic to Home Robotics-assisted Telerehabilitation for Upper Limb (CHISEL)
Hemiparetic weakness is common after stroke and only a small group of patients achieve useful upper limb function despite best rehabilitation efforts.
- Trial name
- NCT05212181
- Testing
- H-Man
- Where
- Singapore
- Volunteers
- 12 people
- Sponsor
- Tan Tock Seng Hospital
Stroke
Efficacy Study of FES Controlled by Electromyographic Signal for the Treatment of Upper Limb in Post-stroke Patients
Goal of the present study is to evaluate the efficacy of Myoelectrically-controlled Functional Electrical Stimulation (MeCFES) for the rehabilitation of upper limb in post-stroke patients.
- Trial name
- RiSES (NCT03019744)
- Testing
- MeCFES-assisted task-oriented upper limb rehabilitation, Usual Care task-oriented upper limb rehabilitation
- Volunteers
- 82 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Occupational Therapy, Epidemiology
Interactive Self-Management Augmented by Rehabilitation Technologies
Background: Stroke is a leading cause of long-term disability in the US. Mild stroke comprises half of stroke hospital admissions, but most people with mild stroke receive no rehabilitation services.
- Conditions
- Occupational Therapy, Epidemiology, Neurologic Disorder
- Trial name
- iSMART (NCT04743037)
- Testing
- iSMART
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Washington University School of Medicine
Stroke, Acute Ischemic
Community Health Worker Assisted Task Specific and Cognitive Therapy at Home With Exposure After Stroke
CATCHES is a novel intervention for preliminary testing, integrating Task Specific Therapy at home guided by Community Health Workers (CHW) under supervision of a licensed Physical Therapist (PT) guided by telehealth based…
- Trial name
- CATCHES (NCT06314308)
- Testing
- CATCHES
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Columbia University
Biofeedback, Rehabilitation
Effects of Myoelectric Biofeedback on Upper Limb Function in Post-stroke Patients
The purpose of this clinical trial is to investigate the effect of myoelectric biofeedback therapy on upper limb function in elderly patients with cerebral infarction, and to analyze the adjustment of stroke condition and quality…
- Conditions
- Biofeedback, Rehabilitation, Cerebral Infarction
- Trial name
- NCT06443008
- Testing
- Observation Group
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Stroke Patients
Prevention and Treatment of Reperfusion Injury After Mechanical Thrombectomy in Acute Ischemic Stroke
Ischemic stroke accounts for 80% of all strokes and there is a lack of effective treatment options.Mechanical thrombectomy can significantly improve the vascular recanalization rate and reduce the disability rate of stroke, but…
- Trial name
- NCT05282290
- Testing
- Antihypertensive drugs (no restriction on the type of drugs)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital