Clinical trials: Strokes
Cerebrovascular Accident, Stroke, Acute
Fabry and Cardiomyopathy (FaCard)
Primary objective and endpoint is the analysis of the long-term course of lyso-Gb3 and its clinical correlation to the progression of the cardiomyopathy in N215S-Fabry patients.
- Conditions
- Cerebrovascular Accident, Stroke, Acute, Cerebral Stroke
- Trial name
- FaCard (NCT01429597)
- Where
- Germany
- Sponsor
- CENTOGENE GmbH Rostock
Moyamoya Disease, Ischemic Cerebral Infarction
NBP in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular Events
An extracranial-to-intracranial (EC-IC) revascularization is the most widely used treatment to improve cerebral perfusion in patients with moyamoya disease (MMD), and it has been shown to reduce the risk of subsequent stroke and…
- Conditions
- Moyamoya Disease, Ischemic Cerebral Infarction, Ischemic Stroke, Ischemic Cerebrovascular Accident
- Trial name
- NICE-MMD (NCT04205578)
- Testing
- dl-3-n-butylphthalide (NBP), Normal Saline 0.9% Infusion Solution
- Where
- 2 sites in China
- Volunteers
- 450 people
- Sponsor
- yuanli Zhao
Muscle Spasticity, Stroke
OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity
This is a safety and efficacy study of onabotulinumtoxinA in poststroke patients with upper limb spasticity.
- Trial name
- NCT02145676
- Testing
- onabotulinumtoxinA
- Where
- 2 sites in United States, Canada
- Volunteers
- 53 people
- Sponsor
- Allergan
Stroke
The Relationship of Trunk Control With Lower Extremity Sense, Balance and Gait in Stroke
Cerebrovascular accident is the third leading cause of death in developed countries after heart disease and cancer. In adults, it ranks first among neurological diseases in terms of causing death and disability.
- Trial name
- NCT05244850
- Testing
- Test
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Stroke, Acute
The Effectiveness of Waiting Room Posters for Stroke Education
The purpose of this study is to determine the effectiveness of posters in improving patient awareness and knowledge of the signs and symptoms of stroke. The control group study will be conducted in the first two weeks.
- Trial name
- NCT03391713
- Testing
- Poster
- Where
- Malaysia
- Volunteers
- 1,064 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Stroke
Neuroplastic Change in Myelin of the Brain
The main goal of this research is to advance understanding of how stroke changes both the structure and function of the brain. The investigators will determine which is the key driver of recovery of arm function after stroke…
- Trial name
- Myelin (NCT01937910)
- Testing
- TRAIT Task
- Where
- Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Stroke, Acute
Timed Interval Measurement of Eotaxin in Stroke Study
Stroke is caused by sudden changes in blood flow in the brain. This can be fatal or can result in permanent disability. A fast diagnosis is essential to initiate effective interventions and optimize benefits to patients.
- Trial name
- TIMES (NCT03521882)
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Acute Ischemic Stroke From Large Vessel Occlusion
Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter
The objective of this study is to assess the safety and effectiveness of mechanical thrombectomy (MT) using the ANA funnel catheter in its intended use, which is to facilitate the navigation and deployment of other neurovascular…
- Trial name
- ATHENA (NCT06370182)
- Testing
- ANA Funnel Catheter, Control
- Where
- 22 sites in United States, France and 3 more
- Volunteers
- 327 people
- Sponsor
- Anaconda Biomed S.L.
Type 2 Diabetes Mellitus
Prediction of Findings From the Ongoing CAROLINA Trial Using Healthcare Database Analyses
This cohort study was initiated to predict the findings of CAROLINA trial in a real world setting using electronic claims data from insurance databases with results anticipated prior to the completion of CAROLINA.
- Trial name
- NCT03648424
- Where
- United States
- Volunteers
- 48,262 people
- Sponsor
- Brigham and Women's Hospital
Acute Ischemic Stroke AIS, Impaired Consciousness
Bovis Calculus Stativus Treat Acute Cerebral Ischemic Stroke With Impaired Consciousness
Acute ischemic stroke (AIS) is a severe and life-threatening condition, with 35% of AIS patients experiencing impaired consciousness upon admission within 24 hours of onset.
- Trial name
- ASCENT-BC (NCT07240467)
- Testing
- Bovis Calculus Stativus (BCS)
- Volunteers
- 220 people
- Sponsor
- Xiang Luo
Stroke, Subacute Stroke
Task Specific Training and Conventional Physical Therapy on Ankle Dorsiflexion in Sub-acute Stroke Patients
This study is a randomized clinical trial designed to compare two physiotherapy rehabilitation approaches for people in the sub-acute phase after stroke (2-6 months after stroke).
- Trial name
- NCT07338032
- Testing
- Task-Specific Training Combined With Conventional Physiotherapy, Conventional Physiotherapy for Ankle Dorsiflexor Strengthening
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- University of Lahore
Hemorrhagic Stroke, Intracerebral Hemorrhage (ICH)
Efficacy, Safety and Tolerability of BAF312 Compared to Placebo in Patients With Intracerebral Hemorrhage (ICH).
This is a randomized, placebo-controlled, subject and investigator-blinded study to evaluate efficacy, safety and tolerability of BAF312 in participants with intracerebral hemorrhage (ICH)
- Trial name
- NCT03338998
- Testing
- BAF312 solution, BAF312 tablet
- Where
- 11 sites in United States
- Volunteers
- 32 people
- Sponsor
- Novartis Pharmaceuticals
The Aim the Study is to Collect and Analyze Data on Patients With Acute Ischemic Stroke During Intravenous Thrombolytic Therapy With Alteplase
Russian Prospective Multicenter Registry Study of Intravenous Thrombolytic Therapy for Acute Ischemic Stroke
Russian prospective multicenter registry study of intravenous thrombolytic therapy for acute ischemic stroke.
- Trial name
- IVT-AIS-R (NCT04674293)
- Testing
- Revelisa
- Where
- Russia
- Volunteers
- 500 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Cerebrovascular Accident
Efficacy Study of the LARA Wheelchair System for Subacute Stroke Patients
This study will test the effectiveness of a new lever drive wheelchair, LARA - Lever Actuated Resonance Assistance. LARA facilitates patients in performing a high amount of practice using their moderate to severely impaired upper…
- Trial name
- NCT02830893
- Testing
- LARA, Standard
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, Irvine
Hyponatremia, SIADH
Tolvaptan for Patients With Acute Neurological Injuries
Hyponatremia occurs frequently in patients with acute brain injury in the days to weeks following injury, and may contribute to adverse outcome.
- Trial name
- NCT02545114
- Testing
- Tolvaptan
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Polderman, Kees, H., MD, PhD
Stroke
CUHK Jockey Club HOPE 4 Care Programme - Ankle Robot
The Hong Kong Jockey Club Charities Trust has supported CUHK to launch a three-year project 'CUHK Jockey Club HOPE4Care Programme' to implement four evidence-based advanced rehabilitation technologies in 40 local elderly day care…
- Trial name
- NCT03808428
- Testing
- Ankle Group
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Dysphagia, Stroke
Changes in Sensitivity, Taste and Smell in Stroke Patients
This study evaluates changes in swallowing using endoscopic swallowing studies and measuring of pharyngeal sensitivity, taste and smell in stroke patients.
- Trial name
- 5S (NCT03240965)
- Testing
- FEES (flexible endoscopic evaluation of swallowing), Sensitivity threshold, Taste-/smell-test
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Stroke, Ischemic, Transient Ischemic Attack
TIA Scores' Mortality Predictions and Recurrent TIA and Stroke Prediction
Our study adopts a prospective design. Our research aims to determine the significance of ABCD2, ABCD3-I, Canadian TIA Score, and NIHSS Score in predicting the likelihood of ischemic stroke within 30 days in patients presenting…
- Trial name
- NCT06515392
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Saglik Bilimleri Universitesi
COVID-19 Stress Syndrome, COVID-19 Vaccine Adverse Reaction
COVID-19 Vaccination Detoxification in LDL-C
The study hypothesizes that SARS-CoV-2 vaccination poisoning hibernates in human host in Low Density Lipoprotein Cholesterol (LDL-C). The clinical trial is a follow-up from the intervention trial with NCT number NCT05711810.
- Conditions
- COVID-19 Stress Syndrome, COVID-19 Vaccine Adverse Reaction, COVID-19-Associated Thromboembolism, COVID-19 Post-Intensive Care Syndrome
- Trial name
- NCT05839236
- Testing
- Atorvastatin Calcium Tablets
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Yang I. Pachankis
Ischemic Stroke, Thrombolytic (t-PA) Treatment
Long-Term Survival After Ischaemic Stroke: Ebrictus Study
A number of large trials have confirmed the benefits of thrombolysis in acute stroke, but there are gender differences. The authors sought to examine the relationship between sex and outcome after thrombolysis.
- Conditions
- Ischemic Stroke, Thrombolytic (t-PA) Treatment, Gender Bias, Long Term Adverse Effects
- Trial name
- EBRICTUS (NCT03247036)
- Testing
- IV thrombolytic (t-PA) treatment vs not
- Where
- Spain
- Volunteers
- 21,000 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
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