Clinical trials: Strokes
Neuropathy, Stroke
Effect of Spasticity on Tibial Nerve Entrapment
Stroke is the most common cause of mortality and is one of the most common causes of morbidity in the world. Polyneuropathies and entrapment neuropathies are known as the complications of stroke
- Trial name
- NCT06092190
- Testing
- EMG
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- October 6 University
Facial Paralysis, Central, Stroke
Mimic Muscle Volume, Central Facial Palsy Severity and Dysphagia
70 stroke patients with central facial paralysis will be included and their demographic data will be questioned and facial nerve thickness, depressor labi inferior, depressor anguli oris, buccinator and risorius muscles will be…
- Trial name
- NCT06615297
- Testing
- ultrasonographic evaluation
- Volunteers
- 70 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Stroke, Transient Ischemic Attack
Smartwatch-Guided Secondary Prevention After Stroke
After a first stroke or transient ischemic attack (TIA), the risk of recurrence is high in the weeks and months following the initial event.
- Trial name
- WATCH-STEP (NCT07640360)
- Testing
- Smartwatch-Guided Secondary Prevention after Stroke
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Brest
Reversible Cerebral Vasoconstriction Syndrome
RCVS: The Rational Approach to Diagnosis and Treatment
This is a randomized clinical trial of short-acting nimodipine versus twice daily extended release verapamil to treat patients presenting with Reversible Cerebral Vasoconstriction Syndrome (RCVS).
- Trial name
- NCT03150524
- Testing
- TCD- cerebral blood flow velocities, Headache pain score, Neurological examination
- Where
- 2 sites in United States
- Sponsor
- Johns Hopkins University
Stroke
Heart-Brain Retraining for Stroke Rehabilitation
The purpose of this study is to gain a better understanding of how different types of exercise can help people after a stroke. The investigators want to study if different types of exercise will improve the use of arm and hand…
- Trial name
- NCT02076776
- Testing
- Repetitive Task Practice (RTP), Voluntary cycling + RTP, Assisted cycling + RTP
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The Cleveland Clinic
Post-ischemic Stroke
Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine.
This is an extension study to evaluate the long-term safety, tolerability, and efficacy of two dose strengths of dalfampridine-ER.
- Trial name
- MILESTONE℠ (NCT02422940)
- Testing
- dalfampridine-ER 7.5 mg, dalfampridine-ER 10 mg
- Where
- 66 sites in United States, Canada
- Volunteers
- 294 people
- Sponsor
- Acorda Therapeutics
Stroke, Brain Injuries
Clinical Effectiveness of iReadMore for People With Alexia
iReadMore will provide an app-based therapy for people with pure or central alexia. This study aims to test the clinical effectiveness of iReadMore for improving reading accuracy and speed in real world users of the therapy.
- Conditions
- Stroke, Brain Injuries, Aphasia, Alexia
- Trial name
- NCT04849091
- Testing
- iReadMore
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage
REpeated ASSEssment of SurvivorS in Intracerebral Hemorrhage Study
The investigators propose to perform serial detailed cognitive, motor, behavioral, and blood collection follow-up using longitudinal structured telephone interviews of an anticipated 350 ICH survivors enrolled in Minimally…
- Conditions
- Intra Cerebral Hemorrhage, ICH - Intracerebral Hemorrhage, ICH, Hemorrhage
- Trial name
- ICH03 (NCT05611918)
- Where
- 26 sites in United States
- Volunteers
- 350 people
- Sponsor
- Johns Hopkins University
Stroke, Quality of Life
EMG Analysis in ABI: Motor Imagery and Action
This study focuses on electromyographic analysis of upper limb muscle activation in stroke survivors during Motor Imagery (MI) and Action Observation (AO) rehabilitation techniques.
- Conditions
- Stroke, Quality of Life, Mirror Movement
- Trial name
- NCT06230718
- Testing
- Motor Imagery (MI), Action Observation (AO)
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- University of Salamanca
Goal-directed Fluid Therapy
Stroke Volume Variation- Guided Hemodynamic Therapy Versus Oxygen Extraction Ratio-guided Hemodynamic Therapy
The FloTrac/Vigileo is a minimal invasive device assessing flow based hemodynamic parameters by pulse contour analysis based on the radial artery pressure signal.
- Trial name
- NCT05487924
- Testing
- SVV-GDHT, O2ER-GDHT, conventional care
- Volunteers
- 610 people
- Sponsor
- Beijing Tongren Hospital
Neuro-Degenerative Disease
Synaptic Density, Tau and Multiparametric PET-MR in Brain Trauma, Stroke and Mild Cognitive or Behavioral Impairment.
Alzheimer's disease, stroke and TBI are frequently observed brain disorders, causing significant morbidity. For none of these disorders, there are in vivo diagnostic biomarkers available that allow determination of disease…
- Trial name
- NCT03514524
- Testing
- PET-MR imaging
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke, Upper Extremity Paresis
Transcutaneous Vagus Nerve Stimulation for Motor Recovery After Stroke
This study will evaluate the safety and effectiveness of Respiratory-gated Auricular Vagal Afferent Nerve Stimulation (RAVANS) for improving motor recovery after stroke.
- Trial name
- NCT03292159
- Testing
- Active RAVANS concurrent with arm motor training, Inactive RAVANS concurrent with arm motor training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Infant Development, Perinatal Stroke
Behavioral Assessment Method Index
The overall goal of this study is to develop and improve assessment methods for children with and without perinatal arterial ischemic stroke (PAS)/hemiparetic cerebral palsy (HCP).
- Conditions
- Infant Development, Perinatal Stroke, Hemiparesis, Cerebral Palsy
- Trial name
- BAM (NCT07291479)
- Testing
- Non interventional study
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Stroke
Low-frequency Transcranial Magnetic Stimulation To Enhance Motor Recovery In The Subacute Phase After Stroke
Low-frequency repetitive transcranial magnetic stimulation (rTMS) of the unaffected hemisphere (UH) transiently improves motor function in patients in the chronic phase after stroke.
- Trial name
- NCT01333579
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke, Unilateral Spatial Neglect
Therapeutic Serious Game and Rehabilitation of Stroke Patient
The growing field of new technologies offers new perspectives for neurorehabilitation. Serious games are a promising solution in the rehabilitation of cognitive impairments, and they may be useful in the rehabilitation of…
- Trial name
- NCT05661396
- Testing
- Serious game rehabilitation
- Volunteers
- 6 people
- Sponsor
- Hopitaux de Saint-Maurice
Lacunar Strokes
Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts
The aim of this study is to determine in patients with a recent lacunar strokes (<15 days), the natural history of cognitive disturbances and disability.
- Trial name
- DHU-LAC (NCT03552926)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke
Stroke COunseling for Risk REduction
The purpose of this study is to test the efficacy of the Stroke Counseling for Risk Reduction (SCORRE) intervention in increasing accuracy of perceived stroke risk and promoting lifestyle behavior change to reduce stroke risk in…
- Trial name
- SCORRE (NCT03076125)
- Testing
- SCORRE, Attention-Control Activity
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Stroke
Robot Assisted Gait Training in Patients With Infratentorial Stroke
The Effect of Robot Assisted Gait Training in Patients With Infratentorial Stroke
- Trial name
- NCT02680691
- Testing
- Robot, then conventional training, Conventional, then robot training
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Stroke, Spasticity, Muscle
Effects of PNF and Static Stretching on Architecture and Viscoelastic Properties of Hemiplegic Elbow
The patients who were diagnosed with stroke in governmental/university/private hospitals, and who needed rehabilitation because of the increased flexor tone in the elbow joint, decreased range of motion and/or decreased function…
- Trial name
- NCT05626790
- Testing
- Exercise, PNF Stretching, Prolonged Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Self-management, Quality of Life
Stroke - 65 Plus. Continued Active Life.
Since august 2016, the researchers at a highly specialized neurorehabilitation hospital in a Danish region with 1.2 inhabitants have in cooperation with health professionals from a specialized neurorehabilitation in a Danish…
- Trial name
- Stroke65+ (NCT03183960)
- Testing
- Mentor
- Where
- 2 sites in Denmark
- Volunteers
- 69 people
- Sponsor
- Central Jutland Regional Hospital
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