Clinical trials: Strokes
Stroke
Association of Vestibular and Postural Impairments With Functional Status in Stroke
: Stroke is leading cause of long-term disability in individuals. The location and extent of brain injury determines the severity of neurological deficits. The incidence of stroke dramatically increases in old age.
- Trial name
- NCT05139537
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Riphah International University
Aphasia
tDCS and Aphasia Treatment
This project will investigate the use of noninvasive brain stimulation in the form of tDCS (transcranial direct current stimulation) in conjunction with speech-language therapy, for the improvement of language production in…
- Trial name
- NCT01922245
- Testing
- Soterix 1x1 tDCS
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Hunter College of City University of New York
Acute Ischemic Stroke
Evaluation of the Safety and Efficacy of Hemacord HPC, Cord Blood in Subjects With Acute Ischemic Stroke
This is a phase one study investigating the safety and efficacy profile of allogeneic cord blood hematopoietic progenitor cells (HPC, Cord Blood), when administered by intravenous infusion and intrathecal injection, in subjects…
- Trial name
- NCT03735277
- Testing
- HPC, Cord Blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- BHI Therapeutic Sciences
Aphasia
Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function.
To explore the mechanism of five-tone speech training in reshaping language fluency function and the clinical efficacy of aphasia language function, daily communication ability and communication efficiency based on the temporal…
- Trial name
- NCT07329751
- Testing
- Traditional Chinese Medicine Five-Tone Therapy, Melodic Intonation Training, Standard speech therapy; Routine medical treatment; Health education
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fujian University of Traditional Chinese Medicine
Stroke
Thoracolumbar Fascia Thickness in Chronic Stroke Patients
The main objective of this study was to examine the thoracolumbar fascia thickness in chronic stroke patients using objective methods and to reveal the relationship of this flexibility with balance, trunk control, trunk…
- Trial name
- NCT07107295
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara University
Cerebrovascular Accident, Thrombolysis
Prospective Study of Cerebrovascular Accidents (CVA) in 3 French Cities (Besançon, Cayenne and Tours)
The objective of this study is to specify the typology of CVA in French Guiana by prospectively comparing consecutive strokes observed at each of the three study sites (Cayenne, Tours, Besançon)
- Trial name
- AVCBCT (NCT04925869)
- Testing
- Observational study
- Where
- French Guiana
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier de Cayenne
Ischemic Stroke
Effect of Acetaminophen on Neurological Outcome in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment
Neuro-inflammation response plays an important role in the development of acute ischemic stroke(AIS). The aim of this study was to conduct a prospective randomized controlled study on the effect of acetaminophen on long-term…
- Trial name
- ACEAIS (NCT06767969)
- Testing
- Acetaminophen
- Volunteers
- 892 people
- Sponsor
- Beijing Tiantan Hospital
Hemiplegia and/or Hemiparesis Following Stroke
Immersive v/s Non-immersive Virtual Reality in Enhancing Upper Limb Functions Among Individuals With Subacute Stage Hemiplegia
The goal of this randomized controlled trial is to compare the effectiveness of immersive virtual reality combined with conventional therapy to the effectiveness of non-immersive virtual reality combined with conventional therapy…
- Trial name
- NCT06615141
- Testing
- Oculus Quest 3, Neofect Smartboard and Tyromotion Myro
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Gulf Medical University
Stroke, Stroke, Ischemic
Telerehabilitation With Aims to Improve Lower Extremity Recovery Post-Stroke (TRAIL-RCT)
The purpose of this study is to compare the effectiveness of a 4-week lower extremity telerehabilitation protocol with aims to improve lower extremity function to a 4-week attention-controlled education program on lower extremity…
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Cerebral Injury
- Trial name
- TRAIL-RCT (NCT04908241)
- Testing
- TRAIL, EDUCATION
- Where
- 5 sites in Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Stroke, Acute
Volumetric Impedance to Guide Stroke Response
Assess the ability of the Visor System to detect hemispheric bioimpedance asymmetry
- Trial name
- VIGOR (NCT03767842)
- Testing
- Visor System
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Cerebrotech Medical Systems, Inc.
Acute Ischemic Stroke
SUMMIT RISE Study of Acute Ischemic Stroke Patients
SUMMIT RISE Study of Acute Ischemic Stroke Patients
- Trial name
- NCT07436156
- Testing
- Route 92 Medical Reperfusion Systems
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Route 92 Medical, Inc.
Brain Edema, Craniocerebral Trauma
A Comparison Between Two Techniques for Performing Decompressive Craniectomy
The purpose of this study is to compare two surgical techniques for a neurosurgical procedure used to treat cerebral edema (decompressive craniectomy): with watertight duraplasty vs.
- Conditions
- Brain Edema, Craniocerebral Trauma, Infarction, Middle Cerebral Artery
- Trial name
- NCT02594137
- Testing
- Without watertight duraplasty
- Volunteers
- 58 people
- Sponsor
- Hospital of the Restoration, Recife
PET/MR, Stroke Ischemic
PET/MR Multimodal Quantitative Analysis of CBF and CMRGlc in Cerebral Ischemia
Research Purpose: This project focuses on clinical research issues in the diagnosis, treatment, and evaluation of patients with cephalic and carotid atherosclerosis.
- Trial name
- PMQIC (NCT07079345)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Ischemic Stroke
Albumin in Acute Ischemic Stroke Trial
The goal of the trial is to determine whether human albumin, administered within 5 hours of symptom onset, improves the 3-month outcome of subjects with acute ischemic stroke.
- Trial name
- ALIAS (NCT00235495)
- Testing
- Albumin, Saline
- Where
- 89 sites in United States, Canada and 2 more
- Volunteers
- 841 people
- Sponsor
- University of Miami
Aquired Brain Injury, Traumatic Brain Injuries
Effectiveness of a Customized Digital Platform to Increase Coordination of Care and Uptake of Evidence-based Practices
Background: Cardiovascular and neurological conditions are major causes of disability worldwide. Early, intensive rehabilitation is essential but often challenging to access in current healthcare systems.
- Conditions
- Aquired Brain Injury, Traumatic Brain Injuries, Stroke, Cardiovascular Diseases
- Trial name
- NCT06867081
- Testing
- The intervention will be the BRILLIANT Platform, an online platform which provides five Modules aimed at increasing coordination of care and direct rehabilitation time
- Where
- 2 sites in Canada
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Ischemic Stroke, TIA
Colchicine in High-risk Patients With Acute Minor-to-moderate Ischemic Stroke or Transient Ischemic Attack (CHANCE-3)
This study is a multicentre, randomized, double-blind, placebo-controlled, investigator-sponsored study that aims to investigate the efficacy of colchicine in preventing recurrent stroke in the patients with acute…
- Trial name
- NCT05439356
- Testing
- Colchicine
- Where
- 244 sites in China
- Volunteers
- 8,343 people
- Sponsor
- Beijing Tiantan Hospital
Drug Resistance, Microbial
Intestinal Microbiota and Antimicrobial Resistance
Antimicrobial resistance is regarded as one of the major global public health threats, causing at least 700,000 deaths per year.
- Trial name
- NCT03794453
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Acute Ischemic Stroke
PET Perfusion Imaging Techniques and Comparing Them to CT Perfusion Imaging in Stroke
Adult patients who are diagnosed with an acute supratentorial ischemic stroke within 48 hrs of onset will be enrolled into the study. Participants will undergo both a CT Scan and PET scan within 7 days of onset.
- Trial name
- NCT04571177
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Stroke, Intra Cerebral Hemorrhage
Influence of Cerebral Oedema in Intracerebral Haemorrhage
In 2020, IntraCerebral Haemorraghe (ICH) remains the most devastating type of stroke. Besides stroke unit care, no specific treatment has been proven effective yet.
- Trial name
- COPITCH (NCT04621357)
- Testing
- Brain MRI, Biological biomarkers
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Lille
Complication, Postoperative
Perioperative Fluid Management: Goal-directed Versus Restrictive Strategy
There is no ideal "cookbook recipe" for fluid prescription that would fit every surgical patient. In this study, the investigators working hypothesis is that the adoption of an integrative algorithm for perioperative fluid and…
- Trial name
- NCT02625701
- Testing
- Goal-directed therapy, Restrictive fluid therapy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Geneva
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