Clinical trials: Strokes
Acute Basilar Artery Occlusion, Endovascular Therapy
The Efficacy and Safety of Endovascular Therapy for Acute Ischemic Stroke Due to Large Core Infarction
This study assesses the efficacy and safety of endovascular therapy in patients with acute basilar artery occlusion with large core infarction within a multicenter, prospective, open-label, blinded endpoint, randomized controlled…
- Conditions
- Acute Basilar Artery Occlusion, Endovascular Therapy, Large Core Infarction
- Trial name
- NCT07333950
- Testing
- Endovascular Recanalization Strategy, Best Medical Management
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Beijing Tiantan Hospital
Stroke
Effects of Augmented Reality (AR) and Transcranial Direct Current Stimulation (tDCS)
The aim of this randomized controlled trial is to determine the effects of Augmented Reality (AR)-based balance training on improving balance and postural control in chronic stroke survivors and whether the addition of…
- Trial name
- NCT07629791
- Testing
- Augmented reality combined with tDCS & Convention therapy
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Stroke, Intracardiac Thrombus
Brain MRI in Stroke Patients With Intracardiac Thrombus
Acute infarction patterns have been described in cardioembolic stroke, mainly with atrial fibrillation (AF) or patent foramen ovale.
- Trial name
- BRAIN IRM (NCT04456309)
- Testing
- No intervention,
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke
Feasibility of the Adapted H-GRASP Feedback Program in the Chronic Phase Post Stroke.
In a recent cross-sectional study, it was shown that people with a good observed upper limb (UL) motor function but low perceived UL activity show a reduced daily-life UL activity.
- Trial name
- NCT05227521
- Testing
- Adapted H-GRASP feedback program
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- KU Leuven
Stroke
Robot Mediated Therapy-Feasibility Study and Preliminary Effects
The goal of this clinical trial is to investigate the feasibility of the application of robot mediated impairment-training (RMIT) and robot mediated task-specific training (RMTT) in acute stroke patients with upper limb…
- Trial name
- NCT05729633
- Testing
- Robot mediated upper limb therapy
- Volunteers
- 4 people
- Sponsor
- Changi General Hospital
Stroke
Non-invasive Neuromodulation NESA Application in the Rehabilitation of Stroke Sequelae
To evaluate whether NESA microcurrents can be used as an effective treatment for various sequelae present in stroke patients, specifically in the treatment of spasticity, balance, pain; and whether it affects quality of life…
- Trial name
- NCT05853952
- Testing
- Non-invasive Neuromodulation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Las Palmas de Gran Canaria
Stroke, Ischemic
Effect of Transcutaneous Vagus Nerve Stimulation on Upper Limb Function in Stroke Patients
The goal of this interventional study is to investigate the therapeutic efficacy of non-invasive vagus nerve stimulation on upper limb function in chronic stroke patients .
- Trial name
- NCT06048055
- Testing
- Transcutaneous auricular vagus nerve stimulation, selected physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cerebrovascular Accident, Hemiparesis
Effects of Strength Training on Upper-Limb Function in Post-Stroke Hemiparesis
Our overall goal is to develop therapeutic interventions to improve upper-limb motor function in hemiparetic persons based on an improved understanding of the mechanisms responsible for its loss and recovery.
- Trial name
- NCT00037908
- Testing
- Strength training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- US Department of Veterans Affairs
Acute Ischemic Stroke, Endovascular Thrombectomy
The Prediction of Hemorrhage Transformation by Cerebral Autoregulation in AIS Patient After Endovascular Thrombectomy
This observational study was designed for observe the cerebral hemodynamics and dynamic cerebral autoregulation (dCA) after endovascular thrombectomy (EVT) in acute ischemic stroke (AIS) patients.
- Conditions
- Acute Ischemic Stroke, Endovascular Thrombectomy, Dynamic Cerebral Autoregulation
- Trial name
- PHASE (NCT06361017)
- Testing
- endovascular thrombectomy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Motor Cortex; Lesion
Imaging Laterality in Chronic Stroke Patients
In healthy individuals, unimanual movement (with either the left or right hand) is associated with activity in a network of predominantly contralateral brain regions, including the primary motor cortex (PMC).
- Trial name
- NCT03584425
- Testing
- Rasch modified version of the Fugl-Meyer Motor assessment, Anatomical image acquisition, Functional MRI task and acquisition
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Chronic Troublesome Sialorrhea, Cerebral Palsy
Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability
The objective of this study is to investigate the efficacy and safety of NT 201 compared with placebo for the treatment of chronic troublesome sialorrhea associated with neurological disorders (e.g.
- Conditions
- Chronic Troublesome Sialorrhea, Cerebral Palsy, Stroke, Traumatic Brain Injury
- Trial name
- SIPEXI (NCT02270736)
- Testing
- NT 201
- Where
- 31 sites in Georgia, Hungary and 4 more
- Volunteers
- 256 people
- Sponsor
- Merz Pharmaceuticals GmbH
Stroke
rTMS and Conventional Physical Therapy After Stroke
Given previous evidence that non invasive brain stimulation enhances the effects of conventional therapies, this randomized sham-controlled trial with 4-weeks follow-up aimed to determine if the repetitive transcranial magnetic…
- Trial name
- NCT01875536
- Testing
- rTMS, conventional physical therapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Laparoscopic Surgery
The Use of Tidal Volume Challenge of Dynamic Parameters During Laparoscopic Surgery
Laparoscopy is increasingly used for major abdominal and pelvic surgery. As this approach is also recommended in elderly patients with serious comorbidities, optimal fluid therapy guidance during this procedure is important.
- Trial name
- NCT03467711
- Testing
- tidal volume challenge, volume expansion
- Where
- South Korea
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Hemispatial Neglect
The Effectiveness of Transcranial Magnetic Stimulation and Mirror Therapy in Hemispatial Neglect
The aim of this study is to evaluate the effectiveness of continuous Theta Burst Stimulation added to mirror therapy on neglect associated with stroke.
- Trial name
- NCT07228871
- Testing
- Mirror Therapy, cTBS, Cognitive rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Ankara Etlik City Hospital
Stroke
The Missing Link- Development and Feasibility Evaluation of Person-centred Transitions From the Stroke Unit to the Home
The aim is to design, implement and evaluate new person-centred transitions between stroke units and the home. The development of person-centred transition will be performed together by people with stroke, significant others…
- Trial name
- Missing Link (NCT02925871)
- Testing
- Co-designed person-centred care transitions, Current care transitions
- Where
- 2 sites in Sweden
- Volunteers
- 49 people
- Sponsor
- Karolinska Institutet
Craniectomy, Trephined Syndrome
External Post-Operative Skull Prosthesis to Prevent Sunken Flap Syndrome in Craniectomy Patients
Patients that undergo decompressive craniectomy are at risk of delayed changes in brain function known as "Sunken Flap Syndrome" or "Syndrome of the Trephined." The goal of this clinical trial is to see if placing a prosthetic…
- Conditions
- Craniectomy, Trephined Syndrome, Traumatic Brain Injury (TBI) Patients, Ischemic Stroke
- Trial name
- ExO-Skull (NCT06899711)
- Testing
- External Cranial Prosthesis
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Johns Hopkins University
Stroke
Comparative Effects of Virtual Reality and Frenkel's Exercises in Patients With Stroke.
To compare the effects of Virtual reality and Frenkel's exercises on balance, gait and quality of life in patients with stroke.
- Trial name
- NCT06509698
- Testing
- virtual reality, Frenkel's exercise
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Basal Ganglia Hemorrhage, Intraventricular Hemorrhage
RAINBOW-ICH Trial of AI Guided Minimally Invasive Neurosurgery for ICH
Intracerebral hemorrhage (ICH) is one of the most devastating forms of stroke, with high rates of death and disability worldwide. Despite advances in medical and surgical care, effective therapeutic options remain limited.
- Conditions
- Basal Ganglia Hemorrhage, Intraventricular Hemorrhage, Brainstem Stroke, Intracranial Hemorrhage, Spontaneous
- Trial name
- RAINBOW-ICH (NCT07205263)
- Testing
- AI-assisted robotic-guided endoscopic hematoma evacuation, Conventional craniotomy, AI-assisted robotic-guided puncture and hematoma evacuation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke
Tolerability of Enecadin (INN) in Acute Ischemic Stroke Trial - TEST
The main objective of this study is to investigate the tolerability of enecadin in patients with acute ischemic stroke. Furthermore, the pharmacokinetics of enecadin in both male and female patients with acute ischemic stroke…
- Trial name
- NCT00331721
- Testing
- Enecadin
- Where
- 26 sites in Austria, Belgium and 1 more
- Volunteers
- 24 people
- Sponsor
- PAION Deutschland GmbH
Stroke, Dysphagia
Improving Dysphagia in Stroke Patients With Chin Tuck Against Resistance Exercise
According to a 2014 report from the Ministry of Health and Welfare, cerebrovascular disease is one of the leading causes of death, with a mortality rate of 51.6 per 100,000 population, ranking fourth among the top ten causes of…
- Trial name
- NCT07630116
- Testing
- Chin Tuck Against Resistance (CTAR), Routine Rehabilitation
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Taichung Veterans General Hospital
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