Clinical trials: Study Adherence, active
Multiple Myeloma or Amyloidosis
Prospective Evaluation of Subcutaneous Administration of Daratumumab by the FreedomEDGE® Infusion System
This study is evaluating a new method for administering daratumumab, a treatment commonly used in the management of multiple myeloma and amyloidosis.
- Trial name
- ESCAPE (NCT07721350)
- Testing
- Subcutaneous Daratumumab Administration Using FreedomEDGE®
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Prediabetic State, PreDiabetes
Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center
The purpose of the study is to assess the feasibility and acceptability of incorporating hands-on nutritional demonstrations to enhance the Diabetes Prevention Program (DPP) curriculum among patients who are at-risk for…
- Conditions
- Prediabetic State, PreDiabetes, Health Knowledge, Attitudes, Practice, Nutrition, Healthy
- Trial name
- NCT06897982
- Testing
- One-arm feasibility pilot of a nutrition intervention to recruit, engage, and retain DPP participants in the safety-net setting in Los Angeles
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Type 2 Diabetes
A Two-armed Real-world Study of Ozempic (OW Semaglutide) to Evaluate Its Adherence and Persistence Compared With Other Anti-diabetic Drugs Among Adult T2DM Patients in China
The study is testing the incidence of MACE and incidence of renal events between Ozempic® users and users with other anti-diabetic medications in T2D patients.
- Trial name
- SPOTLIGHT (NCT07456774)
- Where
- China
- Volunteers
- 100,000 people
- Sponsor
- Novo Nordisk A/S
Laryngeal Carcinoma, Quality of Life (QOL)
Quality of Life and Functional Outcomes in Laryngeal Cancer Patients
Laryngeal squamous cell carcinomas are head and neck malignancies that directly affect both swallowing and voice functions and are associated with a significant deterioration in patients' quality of life throughout the treatment…
- Conditions
- Laryngeal Carcinoma, Quality of Life (QOL), Patient Satisfaction, Voice Quality
- Trial name
- QoL in LSSC (NCT07320820)
- Testing
- Quality of Life Assessment, Patient Satisfaction Assessment, Swallowing Function Assessment
- Volunteers
- 120 people
- Sponsor
- Saglik Bilimleri Universitesi
Anemia
Menstruation and Anemia Research: A Community Health Study
This research is studying if a community-based, community health worker (CHW) led psychosocial intervention improves hemoglobin levels among Black/African American and/or Hispanic or Latino women with anemia compared to standard…
- Trial name
- MARCH (NCT07832526)
- Testing
- Standard of Care, Informational Series and follow-up support
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Michigan
Patient Satisfaction
This Study Will Assess Whether the Treatment Provided by Dentist is Successful in Meeting the Expectations of Patient by Asking Questions Related to Aesthetics, Chewing Ability, Comfort and Phonetics Before and After Providing Treatment and the Patient Will Tell Through Visual Analog Scale
This study aims to assess patient satisfaction after receiving porcelain-fused-to-metal fixed dental prostheses. Patients will be asked about their expectations before treatment and their satisfaction afterward.
- Trial name
- NCT07100678
- Testing
- Porcelain-Fused-to-Metal Fixed Dental Prosthesis
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Khyber College of dentistry
Human Immunodeficiency Virus Infection (HIV), HIV-1 Infection in Adults
Long-Term Real-World Evidence Study to Evaluate Effectiveness, Persistence, Adherence, Safety and Tolerability of Long-acting Cabotegravir Plus Rilpivirine.
The RELATIVITY study is a nationwide, multicenter, ambispective observational cohort evaluating the long-term effectiveness, safety, persistence, and tolerability of long-acting injectable cabotegravir plus rilpivirine (CAB+RPV…
- Trial name
- NCT07703748
- Where
- Spain
- Volunteers
- 3,346 people
- Sponsor
- FUNDACIÓN HOSPITAL UNIVERSITARIO INFANTA LEONOR Y DEL HOSPITAL UNIVERSITARIO DEL SURESTE
Breast Cancer, Hyperglycemia
Risk-Stratified Management of Inavolisib-Induced Hyperglycemia and Patient Adherence
Inavolisib is an effective targeted therapy for certain patients with breast cancer, but it may cause high blood sugar (hyperglycemia) as a side effect.
- Trial name
- NCT07817056
- Testing
- Risk-stratified hyperglycemia management strategy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Rheumatoid Arthritis
Methotrexate in Patients with Early Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disease primarily affecting the small joints of hands and feet, but may also present with systemic, extraarticular features.
- Trial name
- MTXRA (NCT05353829)
- Testing
- Methotrexate
- Where
- 13 sites in Sweden
- Volunteers
- 212 people
- Sponsor
- Region Västerbotten
Fall Prevention
Pilot Feasibility Study of a Fall Prevention Exercise Programme for Community-dwelling Older Adults in Nanchang, China
The goal of this pilot clinical trial is to evaluate the feasibility of a fall prevention exercise programme for older adults living in urban communities in China.
- Trial name
- NCT07341802
- Testing
- Safe & Joyful Walk, Tai Chi
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS)
Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test
The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression).
- Conditions
- Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis
- Trial name
- NCT07158892
- Testing
- Diagnostic Advance Care Planning Discussion, Informational Statement Only
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas at Austin
Nursing Education
Health Nanotechnology Education for Nursing Interns
This quasi-experimental study evaluates the effect of a health nanotechnology educational program on nursing interns' knowledge and self-perceived innovation readiness.
- Trial name
- NCT07795775
- Testing
- Health Nanotechnology Educational Program
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Mona Gabr
Patient Satisfaction, Waiting Times, Patient Pathways, Effect of Lifestyle-related, Clinical and Demographic Parameters on Outcomes
Reducing Waiting Time for Vision Refraction Services
The Out-Patient Departments (OPD) is often the first point of contact for patients seeking healthcare services and involves the coordination of both administrative and clinical processes.
- Trial name
- NCT07416175
- Testing
- VRR service optimization
- Volunteers
- 350 people
- Sponsor
- Seva Canada Society
Acute Coronary Syndrome (ACS), High Bleeding Risk (HBR)
Optimization and Validation of Quality Control Indicators for Coronary Revascularization Based on Antiplatelet Therapy
Study Purpose Coronary heart disease (CAD) is a leading global cause of death, with Acute Coronary Syndrome (ACS) as its acute and life-threatening subtype.
- Conditions
- Acute Coronary Syndrome (ACS), High Bleeding Risk (HBR), Coronary Artery Disease (CAD)
- Trial name
- NCT07354828
- Where
- China
- Volunteers
- 3,500 people
- Sponsor
- Shenyang Northern Hospital
Hearing Loss, Adult-Onset, Tinnitus
AI-assisted Diagnosis, Triage and Assessment of Hearing Loss and Tinnitus
Hearing loss affects approximately 11 million people in the UK, while tinnitus impacts around 7 million. Both conditions can significantly reduce quality of life and are linked to poorer mental health and employment challenges.
- Trial name
- NCT07586098
- Testing
- Artificial Intelligence (AI) Assisted Clinical Decision Support Tool for managing Hearing Loss and Tinnitus
- Where
- United Kingdom
- Volunteers
- 1,500 people
- Sponsor
- Royal Cornwall Hospitals Trust
Breast Cancer, Quality of Life
Factors Influencing Breast Cancer Resection Volumes And Their Impact on Treatment Outcome (FIBRATIO)
The number of breast cancer survivors is constantly growing. Breast conserving surgery (BCS) is equal or superior to mastectomy both regarding survival and quality of life (QoL).
- Conditions
- Breast Cancer, Quality of Life, Patient Satisfaction, Resection Margin
- Trial name
- FIBRATIO (NCT05257577)
- Testing
- Breast conserving surgery
- Where
- 4 sites in Finland
- Volunteers
- 220 people
- Sponsor
- Tampere University Hospital
Breast Neoplasms, Breast Self-Examination
Health Belief Model-Based Survey on Breast Self-Examination Awareness and Practice Among Community-Dwelling Middle-Aged and Older Women
This observational study aims to evaluate the current status of breast self-examination (BSE) practices and related influencing factors among middle-aged and older women in urban communities, using the Health Belief Model (HBM)…
- Conditions
- Breast Neoplasms, Breast Self-Examination, Cancer Screening, Health Belief Model
- Trial name
- HBM-BSE (NCT07149636)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Stage I Colon Cancer AJCC v8, Stage I Rectal Cancer AJCC v8
Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers
This clinical trial develops and tests a mobile health (mHealth) intervention to improve adherence to lifestyle recommendations in colorectal cancer (CRC) survivors and their family caregivers.
- Conditions
- Stage I Colon Cancer AJCC v8, Stage I Rectal Cancer AJCC v8, Stage II Colon Cancer AJCC v8, Stage II Rectal Cancer AJCC v8
- Trial name
- NCT06746012
- Testing
- Discussion, Educational Activity, Internet-Based Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Bone Sarcoma, Osteosarcoma
Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas
Randomized, non-comparative, multicentre exploratory phase II study. Two arms concerning patients with bone sarcoma after the first line therapy: in the first arm, patients will be treated with Regorafenib for a maximum of 12…
- Conditions
- Bone Sarcoma, Osteosarcoma, Ewing Sarcoma, Chondrosarcoma
- Trial name
- REGOSTA (NCT04055220)
- Testing
- Treatment by Regorafenib, Surveillance
- Where
- 16 sites in France
- Volunteers
- 168 people
- Sponsor
- Centre Leon Berard
Cataract Surgery Deneyimi, Cataract Surgery
Katarak Surgery and Care
Although cataract surgery is an effective treatment method for improving visual function, it is important to evaluate the quality of life, daily living activities, independence level and psychosocial well-being of patients in the…
- Trial name
- NCT07807761
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University