Clinical trials: Study Recruitment
Common Cold, Upper Respiratory Tract Infections
Hypertonic Saline Nasal Irrigation and Gargling for the Common Cold.
Viral upper respiratory tract infections (URTI), one of the commonest infection faced by humans, have a significant impact on individuals, families, health service and economy.
- Trial name
- ELVIS (NCT02438579)
- Testing
- Nasal Irrigation & Gargling
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- NHS Lothian
Central Sensitisation, Motor Disorders
Motor Unit Abnormalities After Experimentally Induced Sensitization
Central sensitization is a condition that represents a cascade of neurological adaptations, resulting in an amplification of nociceptive responses from noxious and non-noxious stimuli.
- Trial name
- NCT04361149
- Testing
- Capsaicin Topical Cream (0.075%), Delsys Trigno Galileo System, Excaliber, Natus Medical
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Toronto Rehabilitation Institute
Pulmonary Atelectasis
Descriptive and Comparative Study of Respiratory Function in the Postoperative Cardiac Surgery Patient
The study comprises two different objectives. Longitudinal description of postoperative pulmonary dysfunction in the cardiothoracic surgery patient, and the comparison of two different lungrecruitment strategies.
- Trial name
- NCT03009331
- Testing
- Lungrecruitment manoeuver in prone position., Lungrecruitment manoeuver in supine position.
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Sahlgrenska University Hospital
Mechanical Ventilator Weaning, Respiratory Muscle Training
Muscle Recruitment During Neck Flexion and Inspiratory Muscle Training
Respiratory muscle dysfunction is highly prevalent in patients with prolonged weaning from mechanical ventilation and is strongly associated with weaning failure.
- Trial name
- FLEX (NCT05710432)
- Testing
- Quasi-Isometric Neck Flexion, Inspiratory Muscle Training
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Unity Health Toronto
Assessing Interest in a Platform for Early Phase Clinical Trial Recruitment
Assessing Interest in Web/App Platforms for Early Phase Clinical Trial Recruitment
Study objective: To assess whether the different stakeholders (volunteers, patients, doctors and industry) involved in early phase trials would be interested in using a platform to facilitate recruitment and engagement in this…
- Trial name
- NCT06302647
- Testing
- Questionnaires
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Decreased Lung Compliance, Hypoxia
Alveolar Recruitment Maneuver During Cesarean Section Improves Lung Compliance
The investigators tested the hypothesis that alveolar recruitment maneuver during cesarean section and in women under general anesthesia improves lung compliance and gas exchange.
- Conditions
- Decreased Lung Compliance, Hypoxia, Hypercapnia, Atelectasis
- Trial name
- CSRecGHPyr (NCT01826968)
- Testing
- Alveolar Recruitment maneuver
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- General Hospital Of Pyrgos
Acute Respiratory Distress Syndrom
Selective Lung Recruitment in Moderate to Severe ARDS : a Pilot Study
Acute respiratory distress syndrome (ARDS) is an acute condition affecting the lung after clinical aggression ( infectious process, pancreatitis, acute inflammatory event).
- Trial name
- SRIMSA (NCT06609629)
- Testing
- Selective lung recruitment
- Volunteers
- 10 people
- Sponsor
- University Hospital, Caen
Electrical Impedance Tomography (EIT), Postoperative Pulmonary Complications (PPCs)
EIT-guided PEEP Titration Versus Standard Ventilation in Bariatric Surgery
This study is a prospective, single-center, single-blind, randomized controlled clinical trial. Patients scheduled for laparoscopic bariatric surgery will be selected and randomly assigned to either the EIT-guided individualized…
- Conditions
- Electrical Impedance Tomography (EIT), Postoperative Pulmonary Complications (PPCs), Recruitment, Mechanical Ventilation Complication
- Trial name
- EIT (NCT07207772)
- Testing
- Group P-eit, Group P-8
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Jianbo Wu
Anesthesia, Surgery
Effects of Recruitment Maneuver on Functional Residual Capacity
Recruitment maneuver is frequently used in daily anaesthesia routine to prevent athelectasia and ventilation perfusion mismatch.
- Conditions
- Anesthesia, Surgery, Atelectasis
- Trial name
- NCT04208737
- Testing
- recruitment maneuver
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Dementia, Cognitive Dysfunction
A Relational Research Recruitment and Engagement Intervention for Cognitive Aging Research
Despite well-documented disparities in Alzheimer's disease and related dementia (AD) prevalence, incidence, treatment, and mortality, individuals from disadvantaged backgrounds (e.g.
- Conditions
- Dementia, Cognitive Dysfunction, Alzheimer Disease, Lewy Body Disease
- Trial name
- NCT05444244
- Testing
- Relational Research Recruitment and Engagement Intervention
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Shoulder Pain
Randomized Study in the Prevention of Pain Shoulders After Laparoscopic Surgery
The purpose of this study is to assess shoulder pain at rest (average over the last 24 hours) assessed by visual analogue scale from 0 to 100mm on Day 1.
- Trial name
- POPPLaS (NCT06039761)
- Testing
- Digestive or gynecological surgery by laparoscopy
- Where
- France
- Volunteers
- 190 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Ovarian Reserve
Bone Marrow Transplantation to Promote Follicle Recruitment in Poor Ovarian Reserve
Women delay maternity and, as a consequence, available oocyte number and their quality decrease (9-18% of all IVF patients). Different treatment protocols have been developed nevertheless none of them optimal: the number of…
- Trial name
- NCT02240342
- Testing
- Bone marrow transplant into ovarian artery
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Universitario La Fe
Rotator Cuff Tear
Prospective Study for Safety and Efficacy of InSpace™ in Rotator Cuff Tear Subjects
Title: One-arm, international, multi-center with competitive recruitment, prospective study to assess the safety and efficacy of OrthoSpace's InSpace™ in rotator cuff tear subjects scheduled for surgery of the rotator cuff - A…
- Trial name
- NCT00916994
- Testing
- SpaceGuard Balloon
- Where
- Israel
- Volunteers
- 58 people
- Sponsor
- OrthoSpace Ltd.
Asthma, Chronic Obstructive Pulmonary Disease
Asthma & COPD Guideline Implementation
This is a report of a protocol developed to improve asthma and COPD care in a primary care setting. The study was approved by an Ethics Committee and support by the Canadian Thoracic Society through an unrestrictive grant from…
- Trial name
- NCT01766544
- Testing
- Standard Practice Group (SPG), TISG
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Laval University
Limb-Girdle Muscular Dystrophy, Type 2E
Limb Girdle Muscular Dystrophy Type 2E Recruitment Study
This study is to recruit and establish baseline measurements for potential subjects that may be eligible for a gene therapy trial.
- Trial name
- NCT03492346
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Nationwide Children's Hospital
Alveolar Recruitment Manoeuver, Anesthesia
Effect Alveolar Recruitment Manoeuver on Stroke Volume a Randomized Study
Objective: to compare the effect of alveolar recruitment manouver through stepwise increase and decrease in airway pressure or sustained 30 secondes 30 cmH2O continuous positive airway pressure on cardiac stroke volume estimated…
- Trial name
- hemorecrut-2 (NCT04802421)
- Testing
- alveolar recruitment manoeuver
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Caen
Acute Respiratory Distress Syndrome
Artificial Increase in Chest Wall Elastance as an Alternative to Prone Positioning in Moderate-to-severe ARDS.
During moderate to severe ARDS, sessions of prone positioning lead to lung and chest wall mechanics changes that modify regional ventilation, with a final redistribution of tidal volume and PEEP towards dependent lung regions…
- Trial name
- ALTERPRONE (NCT03719937)
- Testing
- weight on the anterior chest of the patient
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Catholic University of the Sacred Heart
Healthy Cohort
The NICOLA Recruitment Trial (NICOLA-RT)
The Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) is an opportunity to conduct methodology research relevant to many features of a large prospective study.
- Trial name
- NICOLA-RT (NCT01938898)
- Testing
- Invitation letter randomisation
- Where
- United Kingdom
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Septic Shock
Microcirculation Recruitment Using Albumin 20% and Terlipressin in Septic Patients
The aim of this study is to evaluate the effect of combining HSA 20% and terlipressin on the microcirculation in patients with septic shock using the following;- Microcirculation recruitment by Cytocam-IDF.
- Trial name
- NCT05080543
- Testing
- Albumin 20% and terlipressin
- Volunteers
- 36 people
- Sponsor
- Amany Mousa Salama Muhammed
Respiratory Distress Syndrome, Respiratory Insufficiency
Recruitment Manoeuvres in Critically Ill Patients
Diseases of the lungs can be life-threatening. When these organs fail to adequately work, treatments to support their function are offered, often in Intensive Care Units (ICU).
- Conditions
- Respiratory Distress Syndrome, Respiratory Insufficiency, Respiratory Failure, Shock Lung
- Trial name
- RMCIP (NCT05508724)
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University of Oxford