Clinical trials: Stunting, open to volunteers
Stunting, Gender Equality
Evaluation of REACTS-IN, an Intervention to Improve Nutrition, Hygiene, and Sexual and Reproductive Health Services
This is an independent evaluation of World VIsion's 7-year quasi-experimental intervention to improve nutrition, nutrition-related rights and gender equality for women, adolescent girls, and children under five years of age in…
- Conditions
- Stunting, Gender Equality, Acceptability of Health Care, Diet; Deficiency
- Trial name
- REACTS-IN (NCT06362837)
- Testing
- Education intervention on nutrition, gender equity, WASH, sexual and reproductive health rights, school-based iron-folic acid supplement program, Health service training on equitable access to nutrition, health, and sexual and reproductive services
- Where
- 3 sites in Bangladesh, Kenya and 1 more
- Volunteers
- 13,500 people
- Sponsor
- McGill University
Healthy Volunteers
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants
This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors…
- Trial name
- NCT04286464
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pregnancy, Malaria
L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE)
There are few safe, effective, and affordable interventions to improve pregnancy outcomes in low resource settings where the highest rates of poor birth outcomes occur.
- Conditions
- Pregnancy, Malaria, Nutrition, Placental Development
- Trial name
- AGREE (NCT05934318)
- Testing
- L-citrulline
- Where
- Kenya
- Volunteers
- 2,960 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Malnutrition, Child
Hens Hatching Hope
The study is a prospective community-cluster non-randomized trial that will evaluate the effectiveness of a program that will provide 30-day egg vouchers to mothers of 6 to 24 month-old children living in rural areas of Intibucá…
- Trial name
- NCT04721197
- Testing
- Egg vouchers, Standard of Care
- Where
- Honduras
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Stillbirth, Fetal Death
Investigating the Structured Use of Ultrasound Scanning for Fetal Growth
Fetal growth restriction during pregnancy represents one of the biggest risk factors for stillbirth (Gardosi et al, 2013), with 'about one in three term, normally formed antepartum stillbirths are related to abnormalities of…
- Conditions
- Stillbirth, Fetal Death, Fetal Growth Retardation, Small for Gestational Age
- Trial name
- OxGRIP (NCT03662178)
- Where
- United Kingdom
- Volunteers
- 56,000 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Stunting of Growth, Chronic Malnutrition
Pilot Study of a Modified Therapeutic Food Compared With a Standard Nutrient Supplement in Young Children in Rural Guatemala
The goal of this clinical trial is to learn whether a modified food supplement is acceptable and well tolerated by children aged 12 to 24 months with mild-to-moderate stunting in rural Guatemala.
- Trial name
- NCT07804667
- Testing
- Modified Therapeutic Food Formulation, Nutri Listo SQ-LNS
- Where
- Guatemala
- Volunteers
- 36 people
- Sponsor
- Wuqu' Kawoq, Maya Health Alliance
Pregnancy Related, Fetal Growth Retardation
Pregnancy Repository
An essential part of clinical research is the availability and accessibility of human biospecimens for the identification of biomarkers, new treatments and measurement of response to therapy.
- Conditions
- Pregnancy Related, Fetal Growth Retardation, Placental Insufficiency, Preeclampsia
- Trial name
- PR (NCT06339606)
- Testing
- Biospecimen collection
- Volunteers
- 7,000 people
- Sponsor
- Sunnybrook Health Sciences Centre
Adrenal Insufficiency, Growth Disorder
Evaluation of Children With Endocrine and Metabolic-Related Conditions
Background: Endocrine glands give off hormones. Researchers want to learn more about the disorders that affect these glands in children. These disorders might be caused by changes in genes.
- Conditions
- Adrenal Insufficiency, Growth Disorder, Endocrine Diseases, Metabolic Disease
- Trial name
- NCT02769975
- Where
- United States
- Volunteers
- 15,000 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pre-eclampsia, Pre-Term
Study of Pregnancy Pathologies Associated With Placental Abnormalities
Pregnancy pathologies can occur from implantation until childbirth. The investigators are interested in the development mechanisms of these pathologies and aim to develop therapies to treat them.
- Conditions
- Pre-eclampsia, Pre-Term, Fetal Growth Retardation
- Trial name
- NCT05188066
- Testing
- Histology
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Fetal Growth Restriction (FGR)
DIFFUSION WEIGHTED MRI FINDINGS IN FETUSES WITH AND WITHOUT FETAL GROWTH RESTRICTION
This prospective observational study aims to compare fetal brain diffusion-weighted magnetic resonance imaging (DWI) findings in fetuses with and without fetal growth restriction (FGR) and to evaluate the association between…
- Trial name
- NCT07769957
- Testing
- Diffusion-weighted fetal brain MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Fetal Growth Retardation, Fetal Neurodevelopmental Disorder
Fetal Magnetic Resonance Imaging: Z-score Reference Ranges for a Large Patient Population in Normal Neuroimaging Measurement
This study aims to establish the z score reference ranges of fetal head circumference and other measurement of fetal measurements including biparietal diameter, fronto-occipital diameter, length of the corpus callosum, lateral…
- Trial name
- FMZSCORE (NCT07004283)
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Nutrition, Growth
Impact of Diet and Nutrition on Growth and Development in Young Children
The association between nutrition in early life and its long-term health consequences has long been known. However, there is a scarcity of scientific evidence on how nutritional status affects child growth and development in…
- Conditions
- Nutrition, Growth, Development, Stunting
- Trial name
- DIGEST (NCT06018636)
- Where
- Pakistan
- Volunteers
- 832 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Stillbirth
Research On Advanced Diagnostics and Management of All Pregnancies to Prevent Stillbirth (ROADMAPS)
The primary objective of the Stillbirth Research Consortium (SBRC) longitudinal cohort study is to develop and evaluate a robust multivariable prediction model to identify pregnancies at <14 weeks gestation that are at increased…
- Trial name
- ROADMAPS (NCT07745101)
- Where
- 5 sites in United States
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Iron-Deficiency Anemia, Neurobehavioral Manifestations
Impact of Iron Deficiency Anemia on Neurobehavioral and Cognitive Development in Children Aged 6 to 24 Months
The goal of this observational study is to explore the relationship between iron-deficiency anemia and neurobehavioral development in children aged 6-24 months.
- Conditions
- Iron-Deficiency Anemia, Neurobehavioral Manifestations, Growth Disorders, Nutritional Status
- Trial name
- NCT06662045
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Pingshan District Maternal & Child Healthcare Hospital of Shenzhen
Hypertension, Pregnancy-Induced, HELLP Syndrome
PROTECT-Africa: Biomarker Validation for Preeclampsia Triage
Preeclampsia is a serious high blood pressure condition that can develop during pregnancy. It is one of the leading causes of death and illness for mothers and babies in Africa.
- Conditions
- Hypertension, Pregnancy-Induced, HELLP Syndrome, Eclampsia, Fetal Growth Retardation
- Trial name
- PROTECT-Africa (NCT07810439)
- Where
- Zimbabwe
- Volunteers
- 1,106 people
- Sponsor
- Africa Clinical Research Network (ACRN)
Pregnancy, Neonatal Mortality
Scalable Public Health Empowerment, Research, and Education Sites (SPHERES)
SPHERES is a health service research trial in the Indonesian primary care system designed to improve health system performance using a structured data-driven action model.
- Conditions
- Pregnancy, Neonatal Mortality, Tuberculosis, Hepatitis B
- Trial name
- SPHERES (NCT07126041)
- Testing
- Prescription for Action (SPHERES Model)
- Where
- 2 sites in Indonesia
- Volunteers
- 1,750,000 people, healthy volunteers welcome
- Sponsor
- Oxford University Clinical Research Unit Indonesia
Fetal Growth Restriction, Perinatal Outcome
Relationship of DV Doppler Parameters to Perinatal Outcomes in IUGR vs Non-IUGR
This observational study investigates whether blood flow in the ductus venosus, a small fetal vein measured by Doppler ultrasound, is related to pregnancy outcomes.
- Conditions
- Fetal Growth Restriction, Perinatal Outcome, Pregnancy, High Risk
- Trial name
- DV-FGR (NCT07190157)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Izmir City Hospital
Undernutrition
Effectiveness of Small-Quantity vs Medium-Quantity Lipid-Based Nutrient Supplements for Prevention of Undernutrition in Young Children
Nutrition is essential for a child's growth, brain development, and protection from disease. While breastmilk provides the best nutrition for young infants, children older than six months may not get all the nutrients they need…
- Trial name
- NCT07451951
- Testing
- Medium-quantity lipid-based nutrient supplement (MQ-LNS), Small-quantity lipid-based nutrient supplement (SQ-LNS)
- Where
- 2 sites in Pakistan
- Volunteers
- 1,568 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Prognathism, Retrognathism
Natural History of Craniofacial Anomalies and Developmental Growth Variants
Background: Some head and facial abnormalities are rare and present at birth. Others are more common, and may not show up until puberty. These conditions have different causes and characteristics.
- Conditions
- Prognathism, Retrognathism, Dentofacial Deformities
- Trial name
- NCT02639312
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)