Clinical trials: Subarachnoid Hemorrhage
Brain Injuries, Traumatic Brain Injury
Diet Induced Ketosis for Brain Injury - A Feasibility Study
Each year, approx. 100 patients with severe brain injury is admitted to the Clinic for Neurorehabilitation/TBI Unit, Rigshospitalet.
- Conditions
- Brain Injuries, Traumatic Brain Injury, Subarachnoid Hemorrhage, Stroke
- Trial name
- NCT04308577
- Testing
- Ketogenic diet with added MCT
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Jens Rikardt Andersen
Aneurysmal Subarachnoid Hemorrhage
Early Lumbar Drainage Plus Intrathecal Urokinase in Severe Aneurysmal Subarachnoid Hemorrhage (LD-ITUK)
The LD-ITUK is a multicenter, prospective, randomized, double-blind, blind endpoint, placebo-control design trial. All eligible patients with the diagnosis of severe aSAH will be randomly assigned to the treatment group or the…
- Trial name
- NCT06284642
- Testing
- Urokinase
- Where
- 25 sites in China
- Volunteers
- 424 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Aneurysmal Subarachnoid Hemorrhage
Efficacy and Safety Study of a Low-carbohydrate Tube Feed in Critically Ill Patients Under Insulin Therapy
The purpose of this study is to determine the efficacy and safety of a diabetes-specific tube feed in comparison to an isocaloric, isonitrogenous standard enteral formula in critically ill patients receiving insulin treatment for…
- Trial name
- NCT02503527
- Testing
- Diben 1.5 kcal HP, Fresubin HP Energy Fibre (1.5 kcal)
- Where
- Austria
- Volunteers
- 28 people
- Sponsor
- Fresenius Kabi
Aneurysmal Subarachnoid Hemorrhage (aSAH)
DIND in Patients With aSAH : Real World Study
In recent years, with the active application of clinical monitoring and treatment methods, the survival rate of patients with aneurysmal subarachnoid hemorrhage (SAH) has improved, but still a certain proportion of patients…
- Trial name
- NCT07160088
- Testing
- Observational
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Subarachnoid Hemorrhage, Cerebral Vasospasm
Safety Study of Dantrolene in Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a devastating acute brain injury due to bleeding onto the brain surface from a ruptured aneurysm.
- Trial name
- NCT01024972
- Testing
- Dantrolene
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Massachusetts, Worcester
Head Injuries, Subarachnoid Haemorrhage
Impact of Cranioplasty On Cerebral Perfusion
The purpose of this study is to examine the impact of cranioplasty on cerebral hemodynamic and blood flow as prognostic factor in patients receiving decompressive craniectomy for Head injuries, Subarachnoid haemorrhage…
- Conditions
- Head Injuries, Subarachnoid Haemorrhage, Intra-cerebral Haemorrhage, Cerebral Thrombosis
- Trial name
- CCP (NCT01113645)
- Testing
- Cerebral perfusion evaluation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spontaneous Subarachnoid Hemorrhage
The Bilirubin Levels in Cerebrospinal Fluid of Spontaneous Subarachnoid Hemorrhage Patients
According to Morgan et. al. (J Neurosurg 101:1026-1029, 2004): bilirubin as a cerebrospinal fluid marker of sentinel subarachnoid hemorrhage: a preliminary report in pigs, we're going to test the hypothesis in the cerebrospinal…
- Trial name
- NCT00173095
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Subarachnoid Hemorrhage, Aneurysmal, Time Delay
A Multicenter Registry Study of Aneurysmal SAH
Firstly, this study aims at clarifying the current situation of Emergency treatment of aneurysmal subarachnoid hemorrhage (SAH) in China, and analyzing the influencing factors contributing to transport delay, so as to improve the…
- Trial name
- NCT03094975
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Jian-min Liu
Subarachnoid Hemorrhage
HyperHAES Versus Placebo - Effect on Intracranial Pressure in SAH Patients
The purpose of this study is to determine whether 7.2% NaCl in 6% hydroxyethyl starch will lower intracranial pressure (ICP) in SAH-patients with normal or moderately elevated ICP in a placebo controlled study, and to describe…
- Trial name
- NCT00199706
- Testing
- 7.2% NaCl in 6% hydroxyethyl starch solution
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Aneurysmal Subarachnoid Hemorrhage
Human Albumin for Clinical Outcome in Aneurysmal Subarachnoid Hemorrhages
Aneurysmal subarachnoid hemorrhage (aSAH) is a dreadful acute neurological condition with overwhelmingly high rate of associated morbidities and mortality.
- Trial name
- HASH (NCT06548477)
- Testing
- Human albumin
- Where
- Qatar
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Ischemic and Hemorrhagic Stroke, Subarachnoid Hemorrhage
Early Tracheostomy in Ventilated Stroke Patients 2
Patients with severe ischemic and hemorrhagic strokes, who require mechanical ventilation, have a particularly bad prognosis. If they require long-term ventilation, their orotracheal tube needs to be, like in any other intensive…
- Trial name
- SETPOINT2 (NCT02377167)
- Testing
- Tracheostomy
- Where
- Germany
- Volunteers
- 380 people
- Sponsor
- University Hospital Heidelberg
Subarachnoid Hemorrhage, Spontaneous
Determinants of Rehabilitation Outcomes in Survivors of Primary Subarachnoid Haemorrhage
A retrospective, observational single centre study of electronic medical records of discharged patients who were admitted to from 1 January 2015 to 31 December 2018.
- Trial name
- DETERMINESAH (NCT04357626)
- Testing
- Inpatient Rehabilitation
- Where
- 2 sites in Singapore
- Volunteers
- 114 people
- Sponsor
- Tan Tock Seng Hospital
Aneurysmal Subarachnoid Hemorrhage (aSAH), Headache
Intranasal Sphenopalatine Ganglion Blockade for Headaches Following Aneurysmal Subarachnoid Hemorrhage
In patients with bleeding from a brain aneurysm, severe headache is the most common complaint. However, the pain is difficult to treat. The use of standard pain medications is common, but pain control remains poor.
- Trial name
- NCT07116408
- Testing
- Lidocaine (drug), Tx 360
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wright State University
Subarachnoid Haemorrhagic Stroke
Beta-sitosterol for Subarachnoid Hemorrhage: Mechanistic Analysis of Recovery and Therapy
Subarachnoid Hemorrhage (SAH), a devastating form of stroke, is associated with high mortality and disability rates due to complex secondary brain injuries-including neuroinflammation, oxidative stress, and blood-brain barrier…
- Trial name
- B-SMART (NCT07457333)
- Testing
- Supplementation of β -sitosterol, Standard medical treatment
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Subarachnoid Hemorrhage, Aneurysmal
Noninvasive Assessment of Cerebral Oxygenation and Cardiac Function in Patients With Neurovascular Diseases
This prospective observational study will assess the regional cerebral oxygen saturation and cardiac output non-invasively in patients with subarachnoid hemorrhage during nimodipine administration for the prevention/management of…
- Trial name
- NCT02991157
- Testing
- Nimodipine
- Where
- India
- Volunteers
- 25 people
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Stroke, Cerebral Infarction
SouthErn China REgisTry for Stroke on Traditional Chinese Medicine
Stroke is the first most common cause of death in China and one of the major causes of functional disability in the adult population.The burden of stoke is significantly increased in China in recent years.
- Conditions
- Stroke, Cerebral Infarction, Transient Ischemic Attack, Cerebral Hemorrhage
- Trial name
- SECRETS-TCM (NCT03380481)
- Testing
- observational only-no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Yefeng Cai
Subarachnoid Hemorrhage, Aneurysmal
Artificial Intelligence in Subarachnoid Hemorrhage
The overall aim of this study is to, with the help of computer/data scientist and machine learning processes, analyse collected heart rate variability data in order to evaluate whether specific patterns could be found in patients…
- Trial name
- AISAH (NCT04415736)
- Testing
- No intervention, observational study
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Göteborg University
Subarachnoid Hemorrhage, Platelet Dysfunction
Hemostasis Profile in Patients With Severe Subarachnoid Hemorrhage
Patients with severe subarachnoid hemorrhage (SAH) may present platelet and coagulation dysfunctions immediately after the stroke on admission at the hospital, and persisting up to 3-4 weeks after the onset.
- Conditions
- Subarachnoid Hemorrhage, Platelet Dysfunction, Coagulation Disorder
- Trial name
- NCT03745456
- Testing
- Blood samples for ROTEM and platelet function.
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Traumatic Intracranial Subarachnoid Hemorrhage
Appropriateness of Methodist Health System(MHS) Inter-facility Transfers of Traumatic Intracranial Subarachnoid Hemorrhage and Spontaneous Bleeds for Level-1 Advanced Surgical Intervention
Brain injuries are common and challenging problems faced by emergency physicians. These diagnoses may include traumatic intracerebral hemorrhage, subarachnoid hemorrhage, ruptured cerebral aneurysms, unruptured cerebral…
- Trial name
- NCT06136078
- Testing
- rate of appropriate and inappropriate transfers from Methodist interfacility transfers
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Methodist Health System
Arterial Aneurysm
SMCV Assessment on Brain Swelling in Patients With SAH From Ruptured Artery Aneurysm
Superficial cerebral veins findings in assessment of brain swelling in patients with aneurysmal subarachnoid hemorrhage who underwent intravenenous DSA examinations
- Trial name
- SMCV (NCT05714735)
- Testing
- Cerebral Venography
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Xuanwu Hospital, Beijing