Clinical trials: Subcutaneous Fat
Characteristics of Subcutaneous Tissue
Histopathology Following CCH Injection
To evaluate the histopathology of subcutaneous tissue isolated after single or multiple Collagenase Clostridium Histolyticum (CCH) injection techniques in adult female participants undergoing abdominoplasty.
- Trial name
- NCT04236635
- Testing
- Collagenase Clostridium Histolyticum Single Injection Technique, Collagenase Clostridium Histolyticum Multiple Injection Technique
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Phaeohyphomycosis
Efficacy of PD-1 Monoclonal Antibody in the Treatment of Phaeohyphomycosis
The main objective was to evaluate the clinical efficacy of PD-1 inhibitor (PD-1 monoclonal antibody) in the treatment of skin and subcutaneous mucocytosis infection, including the comparison of immune cell groups before and…
- Trial name
- NCT06796231
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Breast Cancer, Obesity
A Pilot Study of Docosahexaenoic Acid (DHA) in Obese Menopausal Women
This study aims to determine if a supplement of an omega-3-fatty acid (docosahexaenoic - DHA) lowers inflammation in human fat tissue thereby lowering estrogen production and the potential risk for breast cancer.
- Trial name
- NCT01127867
- Testing
- dietary intervention
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Subcutaneous Fat
Clinical Investigation of Non Invasive Fat Reduction
The purpose of this study is to compare non invasive treatments using a YAG and Didode Laser to reduce the volume of fat.
- Trial name
- NCT01842802
- Testing
- Diode Laser, YAG laser
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Cynosure, Inc.
Body Sculpting
Subcutaneous Contouring Using High Intensity Focused Ultrasound
The device delivers High Intensity Focused Ultrasound (HIFU) energy that can disrupt subcutaneous adipose tissue (SAT) to provide a non-invasive approach to body sculpting, such as a reduction in waist circumference.
- Trial name
- NCT01104272
- Testing
- LipoSonix (Ultrasound treatment of Subcutaneous Adipose Tissue)
- Where
- 2 sites in Canada
- Volunteers
- 36 people
- Sponsor
- Medicis Technologies Corporation
Abdominal Subcutaneous Fat
Study to Evaluate the Effect of Injection Lypolysis (Lipodissolve) Treatments to Reduce Body Fat
The combination of phosphatidylcholine (PPC) and deoxycholate (DC) injected into subcutaneous fat is often popularly referred to as "Lipodissolve" therapy.
- Trial name
- NCT00757081
- Testing
- phosphatidylcholine and deoxycholate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- BodyAesthetic Research Center
HIV Infection
Magnetic Resonance Imaging of the Face and Bones
This study will examine risk factors for facial wasting and avascular necrosis (AVN, a type of damage to the hip and other bones) in HIV-infected patients. The prevalence and natural history of AVN are also being evaluated.
- Trial name
- NCT00001762
- Where
- United States
- Volunteers
- 532 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Abdominal Delivery
Closure Versus Non Closure of Subcutaneous Tissue After Cesarean Section in Diabetic Patients
The aim of this study is to determine the surgical site infection rate and the patient's satisfaction for closure of subcutaneous tissue versus non closure of subcutaneous tissue after cesarean delivery in women with diabetes…
- Trial name
- NCT02664285
- Testing
- closure of subcutaneous tissue, No closure of subcutaneous tissue
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Lumbar Disc Herniation
Imaging Characteristics of Chronic Lumbar Disc Herniation From the Perspective of Core Muscles and Subcutaneous Fat Tissue Thickness
Fat infiltration and atrophy of lumbar muscles are related to spinal degenerative conditions, which can be seen reliably on MRI scans of lumbar disc herniation (LDH) patients.
- Trial name
- ICCLDHPCMSFT (NCT05649592)
- Testing
- Magnetic Resonance Hydrolipid Separation Imaging
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Zhan Yunfan
Metabolic Dysfunction-Associated Steatohepatitis (MASH), Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)
A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
The main purpose of this study is to evaluate the safety and tolerability of the study drug LY3849891 in participants with metabolic dysfunction-associated steatotic liver disease (MASLD) who have the patatin-like phospholipase…
- Trial name
- NCT05395481
- Testing
- LY3849891
- Where
- 16 sites in United States, Japan and 1 more
- Volunteers
- 115 people
- Sponsor
- Eli Lilly and Company
Gastric Cancers, Colorectal Cancer
Predictive Effect of Abdominal Fat and Muscle Area Calculated Based on Abdominal CT on Gastric Cancer Patients
This study aims to create a clinical prediction model. Abdominal fat and muscle area also play an important role in the prediction of surgical outcomes in colorectal cancer.
- Conditions
- Gastric Cancers, Colorectal Cancer, Sarcopenia, Obesity and Overweight
- Trial name
- NCT06606912
- Testing
- Skeletal muscle, subcutaneous fat and visceral fat area
- Where
- 3 sites in China
- Volunteers
- 4,000 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Healthy
Relative Efficacy of Vitamins D2 and D3 in Adult Humans
Vitamin D2 in chronic dosing will produce less of an elevation of serum 25(OH)D than will the same dose of vitamin D3.
- Trial name
- NCT01139840
- Testing
- vitamin D2, vitamin D3
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Creighton University
Overweight and Obesity, Metabolic Syndrome
Testing the Adipose Expandability Hypothesis In Vivo During Overfeeding
Adipose, or fat, tissue is a plastic organ that retains the ability to expand and store excess calories during positive energy balance in humans.
- Trial name
- EAT 2 (NCT04583514)
- Testing
- Control, Overfeeding
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Diabetes, Diabetes Mellitus, Type 1
Localisation of Potential Insulin Deposits in Normal Weight and Obese Diabetics Using 6 mm and 12 mm Long Needles
This trial is conducted in Europe. The primary aim of this clinical trial is to locate and compare simulated insulin injections (injections of sterile atmospheric air) in normal weight and obese patients with diabetes mellitus.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Delivery Systems
- Trial name
- NCT00871416
- Testing
- NovoFine® needle 6 mm, NovoFine® needle 12 mm
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Novo Nordisk A/S
Moderate or Severe Submental Fullness
Evaluation of Safety and Efficacy of Deoxycholic Acid Injection (ATX-101) in the Reduction of Submental Fat
To evaluate the safety and efficacy of deoxycholic acid injection in the reduction of submental fat (fat below the chin).
- Trial name
- NCT01305577
- Testing
- Deoxycholic acid injection
- Where
- 30 sites in Belgium, France and 3 more
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- Kythera Biopharmaceuticals
Atrophy
Histology and Ultrasound Pilot Study of HA Gels Adipose Tissue
This study is a single-blind intra-individual comparative study to evaluate the short and medium term tissue response after the injection of 2 brands of hyaluronic acid gels (HA), designed for deep injection, that have been used…
- Trial name
- NCT02868749
- Testing
- Hyaluronic Acid filler
- Where
- 2 sites in Belgium
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Vandeputte, Joan, M.D.
HIV
Epidermal Nerve Fiber Density, Fat and Mitochondrial Parameters in Thai HIV+ Patients on d4T and HIV- Patients
This study will provide the range of Epidermal Nerve Fiber Density (ENFD) typically seen in Thai individuals. ENFD values from Thai HIV-negative subjects without neuropathy will be used as appropriate reference norm for Thai…
- Trial name
- NCT01178684
- Where
- Thailand
- Volunteers
- 113 people
- Sponsor
- SEARCH Research Foundation
Non-Alcoholic Fatty Liver Disease, Obesity, Morbid
Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
The study is aimed To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obesity, Morbid, Brown Fat, Metabolic Disease
- Trial name
- NCT03875625
- Testing
- Bariatric surgery, Dietitian led life style modification intervention, Conventional care (control)
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Cushing Syndrome Related to Cortisolic Adenoma
Pattern of Gene Expression in Adipose Tissue From Patients With Cushing Syndrome
The purpose of this trial is to investigate the impact of cortisol on adipose tissue functions, distribution and morphology. Patient with endogenous blood cortisol excess exhibit changes in adipose tissue, with fat gain in the…
- Trial name
- LIPOCUSH (NCT01688349)
- Testing
- analyze the role of glucocorticoid in AT distribution.
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris