Clinical trials: Subfertility, Female
Infertility, Female
Clinical Efficacy of Virtual Reality During Office Hysteroscopy and Endometrial Biopsy in Subfertility
This study is a comparison between the current standard practice of performing a diagnostic hysteroscopy and a relatively recently developed technology that is added to the standard diagnostic hysteroscopy.
- Trial name
- HYSVIR (NCT04438759)
- Testing
- Oncomfort, commercially available Virtual Reality headset
- Where
- Belgium
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Polycystic Ovary Syndrome, Infertility
Inositol in Letrozol Resistant PCOS Women
Polycystic ovary syndrome (PCOS),is a complex neuro-endocrine disorder affecting approximately 5% to 10% of women in reproductive age.Inositols are considered insulin sensitizers, as they modulate the members of insulin signaling…
- Trial name
- NCT07585396
- Testing
- Myoinositol, Metformin
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Kafrelsheikh University
Environmental Exposure to Harmful Algae and Toxins, Female Subfertility
Analysis of Toxins in Follicle Fluid
Environmental pollutants might be jointly responsible for increase of infertility among women. Especially endocrin active substances seem to be of particular importance.
- Trial name
- NCT01385605
- Where
- Germany
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Infertility Treatment Center Dortmund
Uterine Septum
Reproductive Outcomes Following Uterine Septum Resection
Nowadays, there is little data to validate the performance of surgical hysteroscopies in the case of septate uterus, particularly in the case of incidental discoveries.
- Trial name
- UTER-SEPTUM (NCT05139446)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Strasbourg, France
Infertility, Female, Unexplained Infertility
Serum Kisspeptin Levels in Infertile Women
The study population is comprise of 90 women those age varies between 18-38 year-old. The first group will comprise of 30 women with polycystic ovaries or anovulatory cycles, the second group will comprise of 30 women with…
- Conditions
- Infertility, Female, Unexplained Infertility, Anovulation
- Trial name
- NCT03018314
- Testing
- Blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Subfertility
Does Hormonal Luteal Support After Intra-uterine Insemination (IUI) Increase the Pregnancy Rate?
A randomized study to investigate if hormonal luteal support after intra-uterine insemination (IUI) in ovulation induction cycles with human menopausal gonadotropin increases the pregnancy rate
- Trial name
- NCT00700492
- Testing
- progesterone
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Subfertility
Assessment of Intralipid Efficacy in Women With Unexplained Recurrent Implantation Failure
The study will include 100 women with unexplained recurrent implantation failure undergoing IVF/ICSI cycle. Patients fulfilling the inclusion criteria will be randomised into two groups.
- Trial name
- NCT02487940
- Testing
- Intralipid 20%, Normal saline
- Volunteers
- 100 people
- Sponsor
- Dar El Teb Institute
Subfertility, Female
OCP Pretreatment in PCOS Patients Undergoing ICSI Using Antagonist Protocol
373 women with PCOS undergoing a trial of IVF/ICSI will receive OCP from day 2 of the preceding cycle for 21 days followed by GnRH antagonist COH.
- Trial name
- NCT03881904
- Testing
- 0.075mg gestodene/0.03mg ethinylestradiol
- Where
- Egypt
- Volunteers
- 740 people
- Sponsor
- Ain Shams University
Sub-Fertility
Influence of FSH/LH Ratio in Controlled Ovarian Stimulation
The aim of this study is to compare different FSH/LH ratios in controlled ovarian stimulation
- Trial name
- NCT02994550
- Testing
- FSH/LH
- Volunteers
- 447 people
- Sponsor
- Hospital de Cruces
Pregnancy Related, Infertility, Female
Innovation for Small-scale Experiments: ReceptIVFity Test
The ReceptIVFity acts as a timing-tool for prediction of optimal pregnancy chances and provides insight into the patient's current (two months after sampling) success rate of an IVF/IVF-ICSI treatment.
- Conditions
- Pregnancy Related, Infertility, Female, Subfertility, Female
- Trial name
- ReceptIVFity (NCT06051201)
- Testing
- ReceptIVFity test (vaginal microbiome swab)
- Where
- Netherlands
- Volunteers
- 683 people
- Sponsor
- Erasmus Medical Center
Subfertility, Female, Ovulation Disorder
Low Dose GnRHa Early Luteal Phase Down Regulation Versus GnRHa Ultra-short Protocol for Poor Ovarian Response
The management of the poor responder patients is very difficult. Currently, there is no any standard treatment for poor responder patients.
- Trial name
- NCT02940535
- Testing
- Diphereline (Triptorelin embonate), Decapeptyl (Triptorelin), human menopausal gonadotropin
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Navy General Hospital, Beijing
Ovarian Failure, Thyroid Diseases
Thyroid Function and Autoimmunity in Subfertility Women and Assisted Reproductive Therapy
The assessment of ovarian reserve is well established based on the dosage of anti-Mullerian hormone (AMH). The clinical applicability of detecting thyroid autoantibodies levels has been discussed as a potential marker of…
- Trial name
- NCT06394466
- Testing
- Non Applicable
- Where
- Brazil
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Subfertility, Female
Effect of Sildenafil Citrate Compared to Estrogen as Adjuvant Therapy for Unexplained Infertility
. This study aimed to determine and compare the effect of vaginal sildenafil citrate and estradiol valerate on endometrial thickness, blood flow and pregnancy rates in infertile women.
- Trial name
- NCT05753098
- Testing
- estrogen therapy, Sildenafil, Clomiphene Citrate 50mg
- Where
- Egypt
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Subfertility, Infertility
Analgesia for Endometrial Scratching
The aim of this study is to evaluate whether Ibuprofen alone or combined with lorazepam reduce the pain associated with endometrial scratching/injury.
- Trial name
- NCT02863614
- Testing
- Ibuprofen 600 mg, Lorazepam 1 mg
- Volunteers
- 150 people
- Sponsor
- University of Sao Paulo
Sub Fertility, Female, Fertility Disorders
Effects of Fasting on Success Rates of Assisted Reproductive Techologies
This exploratory study investigates fasting as a potential supportive therapy for infertility treatment in women undergoing in-vitro-fertilization (IVF) / intracystoplamsatic sperm injection (ICSI)
- Conditions
- Sub Fertility, Female, Fertility Disorders, Fertility Issues, Sub-fertility
- Trial name
- KiWuC (NCT04998591)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Charite University, Berlin, Germany
Endometritis; Chronic, Subfertility
The FLORA-project: in Search for the Microbial Cause of Chronic Endometritis and the Most Appropriate Treatment to Obtain a Successful Pregnancy IVF/ICSI
Chronic endometritis is an inflammatory condition of the endometrium. This inflammation can negatively affect fertility and pregnancy. The pathology is frequently (+-10%) observed in women with fertility problems.
- Trial name
- FLORA (NCT05337072)
- Testing
- Microbiome study
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Subfertility, Female, Ovulation Disorder
Serial Progesterone Level Measurements During the Menstrual Cycle in Subfertile Women
Ovulatory dysfunction is identified in 15% of all infertile couples and it accounts for 40% of female infertility. Ovulatory dysfunction may be more subtle in women with regular menses.
- Trial name
- NCT05211583
- Testing
- Serum progesterone levels
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Turgut Aydın
Subfertility
Clinical Effectiveness of Frozen Thawed Embryo Transfer Compared to Fresh Embryo Transfer
The objective of the present randomized controlled study is to compare clinical effectiveness and safety of freezing all embryos followed by frozen-thawed embryo transfer (FET) compared to fresh embryo transfer, in women…
- Trial name
- NCT02570386
- Testing
- Fresh embryo transfer, Frozen embryo transfer
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Male Infertility, Female Infertility
'SPRING'-Study: "Subfertility Guidelines: Patient Related Implementation in the Netherlands Among Gynaecologists"
The purpose of this study is to compare two different strategies to implement the existing Guideline programme on Subfertility, as issued by the Dutch Society of Obstetrics and Gynaecology (NVOG).
- Conditions
- Male Infertility, Female Infertility, Ovarian Hyperstimulation Syndrome, Premature Ovarian Failure
- Trial name
- NCT00119925
- Testing
- patient education, professional audit and feedback (guideline adherence), professional education (communication/shared decision making)
- Where
- 16 sites in Netherlands
- Volunteers
- 5,200 people
- Sponsor
- Radboud University Medical Center
Subfertility, Female
A Cross Sectional Evaluation of Vitamin D Status and Ovarian Reserve Markers
Evaluation of the association between vitamin D (VD) deficiency and ovarian reserve markers in a group of Pakistani sub fertile women was conducted
- Trial name
- NCT05137964
- Testing
- Vitamin D
- Volunteers
- 199 people
- Sponsor
- Australian Concept Medical Center